| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Preece, J W Dalley, D E H Theobald, T W Robbins, G P Reynold. Region specific changes in forebrain 5-hydroxytryptamine1A and 5-hydroxytryptamine2A receptors in isolation-reared rats: an in vitro autoradiography study. Neuroscience. vol 123. issue 3. 2004-03-31. PMID:14706784. |
regions of highest receptor density were observed in the frontal cortex for 5-ht(2a) receptors and in the frontal cortex, dorsal hippocampus and lateral septum for 5-ht(1a) receptors. |
2004-03-31 |
2023-08-12 |
rat |
| M A Preece, J W Dalley, D E H Theobald, T W Robbins, G P Reynold. Region specific changes in forebrain 5-hydroxytryptamine1A and 5-hydroxytryptamine2A receptors in isolation-reared rats: an in vitro autoradiography study. Neuroscience. vol 123. issue 3. 2004-03-31. PMID:14706784. |
by contrast, 5-ht(1a) receptor binding site densities were significantly reduced by 22% in the prelimbic cortex, and significantly increased by between 10 and 50% in the motor cortex, somatosensory cortex, dentate gyrus and ca fields of the hippocampus. |
2004-03-31 |
2023-08-12 |
rat |
| T A Kudina, V V Sudnitsyn, E B Kutyreva, V F Kichigin. [Serotonin reuptake blocker fluoxetine suppresses hippocampal theta oscillation in rabbits during EEG]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 53. issue 5. 2004-03-30. PMID:14658331. |
[serotonin reuptake blocker fluoxetine suppresses hippocampal theta oscillation in rabbits during eeg]. |
2004-03-30 |
2023-08-12 |
Not clear |
| M Joëls, J M Verkuyl, E Van Rie. Hippocampal and hypothalamic function after chronic stress. Annals of the New York Academy of Sciences. vol 1007. 2004-03-25. PMID:14993070. |
in the second study, responses of ca1 hippocampal neurons to serotonin were recorded with microelectrodes. |
2004-03-25 |
2023-08-12 |
rat |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effect of bupropion on hippocampal neurotransmitters and on peripheral hormonal concentrations in the rat. Journal of applied physiology (Bethesda, Md. : 1985). vol 95. issue 2. 2004-03-19. PMID:12692144. |
a microdialysis probe was inserted in the hippocampus, and samples for serotonin, dopamine, and norepinephrine were collected every 20 min before and after the injection of 17 mg/kg of bupropion, for a total sampling time of 180 min. |
2004-03-19 |
2023-08-12 |
rat |
| Janine Prange-Kiel, Gabriele M Rune, Csaba Lerant. Median raphe mediates estrogenic effects to the hippocampus in female rats. The European journal of neuroscience. vol 19. issue 2. 2004-03-18. PMID:14725625. |
the density of serotonin (5-ht) innervation of the strata lacunosum moleculare and radiatum of the ca1 region of the hippocampus was reduced in response to estradiol, as shown by a decrease in the length of fibers (27.6 and 48.3% decrease, respectively) and the number of large varicosities (32.5 and 38.8% decrease, respectively). |
2004-03-18 |
2023-08-12 |
rat |
| L Manuel-Apolinar, A Menese. 8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production. Behavioural brain research. vol 148. issue 1-2. 2004-03-01. PMID:14684258. |
thus, cortical and hippocampal increased on camp production was observed following administration of the 5-ht(1a/7) agonist 8-oh-dpat. |
2004-03-01 |
2023-08-12 |
Not clear |
| N Hanoun, F Saurini, L Lanfumey, M Hamon, S Bourgoi. Dihydroergotamine and its metabolite, 8'-hydroxy-dihydroergotamine, as 5-HT1A receptor agonists in the rat brain. British journal of pharmacology. vol 139. issue 2. 2004-02-27. PMID:12770948. |
7 as expected of 5-ht(1a) receptor partial agonists, dhe and 8'-oh-dhe prevented any subsequent hyperpolarization of ca1 pyramidal cells by 5-ht or 5-ct. 8 through their actions at 5-ht(1a) auto- (in the dorsal raphe nucleus) and hetero-(notably in the hippocampus) receptors, dhe, and even more its metabolite 8'-oh-dhe, can exert both an inhibitory influence on neuronal excitability and anxiolytic effects which might contribute to their antimigraine prophylactic efficiency. |
2004-02-27 |
2023-08-12 |
rat |
| Takashi Yoshitake, Fu-Hua Wang, Eugenia Kuteeva, Kristina Holmberg, Masatoshi Yamaguchi, Jacqueline N Crawley, Robert Steiner, Tamas Bartfai, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 1. 2004-02-25. PMID:14701907. |
enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. |
2004-02-25 |
2023-08-12 |
mouse |
| Takashi Yoshitake, Fu-Hua Wang, Eugenia Kuteeva, Kristina Holmberg, Masatoshi Yamaguchi, Jacqueline N Crawley, Robert Steiner, Tamas Bartfai, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 1. 2004-02-25. PMID:14701907. |
basal and forced swimming (fs) stress-induced release of noradrenaline (na) and serotonin (5-ht) were determined by in vivo microdialysis in the ventral hippocampus of mice overexpressing galanin under the platelet-derived growth factor b promoter (galoe/p) or under the dopamine beta-hydroxylase promoter (galoe/d) (only na). |
2004-02-25 |
2023-08-12 |
mouse |
| Takashi Yoshitake, Fu-Hua Wang, Eugenia Kuteeva, Kristina Holmberg, Masatoshi Yamaguchi, Jacqueline N Crawley, Robert Steiner, Tamas Bartfai, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 1. 2004-02-25. PMID:14701907. |
these results suggest that the na and 5-ht hippocampal afferents in galoe/p mice are hypersensitive to both conditioned and unconditioned stressful stimuli, such as fs, and that this effect is mediated by galanin receptors. |
2004-02-25 |
2023-08-12 |
mouse |
| Thomas Frodl, Eva M Meisenzahl, Peter Zill, Thomas Baghai, Dan Rujescu, Gerda Leinsinger, Ronald Bottlender, Cornelius Schüle, Peter Zwanzger, Rolf R Engel, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Mölle. Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. Archives of general psychiatry. vol 61. issue 2. 2004-02-24. PMID:14757594. |
reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. |
2004-02-24 |
2023-08-12 |
Not clear |
| Krzysztof Tokarski, Agnieszka Zahorodna, Bartosz Bobula, Grzegorz Hes. 5-HT7 receptors increase the excitability of rat hippocampal CA1 pyramidal neurons. Brain research. vol 993. issue 1-2. 2004-02-12. PMID:14642852. |
in the ca1 area of rat hippocampal slices, a combined application of 5-ct, a potent 5-ht(1a) and 5-ht(7) receptor agonist, and way 100635, a selective 5-ht(1a) receptor antagonist, resulted in a reversible increase of the ca1 extracellular population spike amplitude. |
2004-02-12 |
2023-08-12 |
rat |
| Daniel J Rubins, William P Melega, Goran Lacan, Baldwin Way, Alain Plenevaux, Andre Luxen, Simon R Cherr. Development and evaluation of an automated atlas-based image analysis method for microPET studies of the rat brain. NeuroImage. vol 20. issue 4. 2004-02-12. PMID:14683714. |
the accuracy and precision of this method for voi placement was determined using datasets from pet studies of the striatal dopamine and hippocampal serotonin systems. |
2004-02-12 |
2023-08-12 |
rat |
| Veronika Butterweck, Hilke Winterhoff, Miles Herkenha. Hyperforin-containing extracts of St John's wort fail to alter gene transcription in brain areas involved in HPA axis control in a long-term treatment regimen in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12865894. |
fluoxetine increased levels of mineralocorticoid (mr) (17%), glucocorticoid (gr) (18%), and 5-ht(1a) receptor (21%) mrnas in the hippocampus at 8, but not 2, weeks. |
2004-02-10 |
2023-08-12 |
rat |
| Akihiko Oshima, Cornelia Flachskamm, Johannes M H M Reul, Florian Holsboer, Astrid C E Linthors. Altered serotonergic neurotransmission but normal hypothalamic-pituitary-adrenocortical axis activity in mice chronically treated with the corticotropin-releasing hormone receptor type 1 antagonist NBI 30775. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12915860. |
owing to the intricate relationship between crh and serotonin (5-ht), we studied the effects of chronic oral treatment of c57bl6/n mice with the crh-r1 antagonist nbi 30775 (formerly known as r121919) on hippocampal serotonergic neurotransmission during basal (on 15th day of treatment) and stress (forced swimming; on 16th day of treatment) conditions by in vivo microdialysis. |
2004-02-10 |
2023-08-12 |
mouse |
| M T Toczek, R E Carson, L Lang, Y Ma, M V Spanaki, M G Der, S Fazilat, L Kopylev, P Herscovitch, W C Eckelman, W H Theodor. PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy. Neurology. vol 60. issue 5. 2004-02-09. PMID:12629228. |
activation of central serotonin (5-ht)1a receptors, found in high density in brainstem raphe, hippocampus, and temporal neocortex, exerts an anticonvulsant effect in various experimental seizure models. |
2004-02-09 |
2023-08-12 |
human |
| H Waage-Baudet, J M Lauder, D B Dehart, K Kluckman, S Hiller, G S Tint, K K Suli. Abnormal serotonergic development in a mouse model for the Smith-Lemli-Opitz syndrome: implications for autism. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 21. issue 8. 2004-02-09. PMID:14659996. |
using a targeting strategy designed to virtually eliminate dhcr7 activity, we have created a slos mouse model that exhibits commissural deficiencies, hippocampal abnormalities, and hypermorphic development of serotonin (5-ht) neurons. |
2004-02-09 |
2023-08-12 |
mouse |
| Shigekazu Mizokawa, Masaaki Tanaka, Akira Matsumura, Satoshi Nozaki, Yasuyoshi Watanab. Recovery from fatigue: changes in local brain 2-[18F]fluoro-2-deoxy-D-glucose utilization measured by autoradiography and in brain monoamine levels of rat. Neuroscience letters. vol 353. issue 3. 2004-02-09. PMID:14665408. |
rats resting for 1 h showed a significantly increased ratio of 5-hydroxyindoleacetic acid/5-hydroxytryptamine, an index of serotonin turnover, in the frontal cortex, hippocampus, and cerebellum, and the ratio of [3,4-dihydroxyphenylacetic acid+homovanillic acid]/dopamine, an index of dopamine turnover, tended to be increased as compared with the control. |
2004-02-09 |
2023-08-12 |
rat |
| Theresa Schweizer, Anja Birthelmer, Anelise Lazaris, Jean-Christophe Cassel, Rolf Jackisc. 3,4-DAP-evoked transmitter release in hippocampal slices of aged rats with impaired memory. Brain research bulletin. vol 62. issue 2. 2004-02-06. PMID:14638386. |
based on a slice superfusion technique, this study investigated the release of acetylcholine, noradrenaline and serotonin in the hippocampus of aged rats (25-27 months) showing no or severe deficits in a spatial reference-memory task (water maze). |
2004-02-06 |
2023-08-12 |
rat |