| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas J Pucadyil, Amitabha Chattopadhya. Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus. Biochimica et biophysica acta. vol 1663. issue 1-2. 2004-07-22. PMID:15157621. |
removal of cholesterol from bovine hippocampal membranes using varying concentrations of mbetacd results in a concentration-dependent reduction in specific binding of the agonist 8-oh-dpat to 5-ht(1a) receptors. |
2004-07-22 |
2023-08-12 |
cattle |
| Pierre Blier, Gabriella Gobbi, Nasser Haddjeri, Luca Santarelli, Gina Mathew, René He. Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. Journal of psychiatry & neuroscience : JPN. vol 29. issue 3. 2004-07-22. PMID:15173897. |
long-term, but not subacute, antagonism of nk1 receptors in rats increases 5-ht transmission in the hippocampus, a property common to all antidepressant treatments tested thus far. |
2004-07-22 |
2023-08-12 |
mouse |
| R C B Silva, Ana Carolina Gárgaro, M L Brandã. Differential regulation of the expression of contextual freezing and fear-potentiated startle by 5-HT mechanisms of the median raphe nucleus. Behavioural brain research. vol 151. issue 1-2. 2004-07-19. PMID:15084425. |
5-ht projections from this nucleus to the hippocampus are implicated in the acquisition and expression of contextual fear (background stimuli), as assessed by freezing. |
2004-07-19 |
2023-08-12 |
rat |
| Els van Riel, Neeltje G van Gemert, Onno C Meijer, Marian Joël. Effect of early life stress on serotonin responses in the hippocampus of young adult rats. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150736. |
effect of early life stress on serotonin responses in the hippocampus of young adult rats. |
2004-07-16 |
2023-08-12 |
rat |
| Els van Riel, Neeltje G van Gemert, Onno C Meijer, Marian Joël. Effect of early life stress on serotonin responses in the hippocampus of young adult rats. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150736. |
in this study, we investigated the effects of early life stress on several aspects of serotonin (5-ht) transmission in hippocampus, later on in life. |
2004-07-16 |
2023-08-12 |
rat |
| Els van Riel, Neeltje G van Gemert, Onno C Meijer, Marian Joël. Effect of early life stress on serotonin responses in the hippocampus of young adult rats. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150736. |
we conclude that maternal deprivation can alter specific aspects of hippocampal 5-ht transmission later on in life, possibly by post-translational modification of the 5-ht1a-receptor or changes in the 5-ht1a-receptor signal transduction pathway. |
2004-07-16 |
2023-08-12 |
rat |
| G Csaba, Barbara Knippel, Cs Karabélyos, Agnes Inczefi-Gonda, Mónika Hantos, L Tóthfalusi, Kornélia Teke. Effect of treatment at weaning with the serotonin antagonist mianserin on the brain serotonin and cerebrospinal fluid nocistatin level of adult female rats: a case of late imprinting. Life sciences. vol 75. issue 8. 2004-07-13. PMID:15193954. |
brain serotonin levels significantly decreased in four regions (hippocampus, hypothalamus, striatum and brainstem), without any change in the cortex. |
2004-07-13 |
2023-08-12 |
rat |
| Yasuyuki Abe, Atsushi Aoyagi, Takao Hara, Kazumi Abe, Reina Yamazaki, Yoshihiro Kumagae, Shunji Naruto, Kazuo Koyama, Shinji Marumoto, Keiko Tago, Narihiro Toda, Kazuko Takami, Naho Yamada, Mayuko Ori, Hiroshi Kogen, Tsugio Kanek. Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease. Journal of pharmacological sciences. vol 93. issue 1. 2004-07-09. PMID:14501158. |
actual simultaneous elevation of extracellular levels of 5-ht and ach in the rat hippocampus was confirmed by microdialysis. |
2004-07-09 |
2023-08-12 |
mouse |
| John F Cryan, Olivia F O'Leary, Sung-Ha Jin, Julie C Friedland, Ming Ouyang, Bradford R Hirsch, Michelle E Page, Ashutosh Dalvi, Steven A Thomas, Irwin Luck. Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 21. 2004-07-09. PMID:15148402. |
microdialysis studies demonstrated that the ability of fluoxetine to increase hippocampal serotonin was blocked in dbh(-/-) mice, whereas citalopram's effect was only partially attenuated. |
2004-07-09 |
2023-08-12 |
mouse |
| Pilar Rosel, Belén Arranz, Mikel Urretavizcaya, Miguel Oros, Luis San, Miguel Angel Navarr. Altered 5-HT2A and 5-HT4 postsynaptic receptors and their intracellular signalling systems IP3 and cAMP in brains from depressed violent suicide victims. Neuropsychobiology. vol 49. issue 4. 2004-07-06. PMID:15118356. |
serotonin 5-ht2a and 5-ht4 binding parameters and their second messengers 1,4,5-inositol triphosphate (ip3) and cyclic adenosyl monophosphate (camp) were studied in the frontal cortex, hippocampus, caudate nucleus and amygdala of 19 control subjects and 19 antidepressant-free, violent suicide victims. |
2004-07-06 |
2023-08-12 |
human |
| Hiske M van der Stelt, Laus M Broersen, Berend Olivier, Herman G M Westenber. Effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats. Psychopharmacology. vol 172. issue 2. 2004-06-28. PMID:14647968. |
effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats. |
2004-06-28 |
2023-08-12 |
rat |
| Chan Park, Keumok Cho, Jong Hoon Ryu, Ki Soon Shin, Junghye Kim, Heekyung Ahn, Youngbuhm Hu. 7-Nitroindazole upregulates phosphorylated cAMP response element binding protein, polysialylated-neural cell adhesion molecule and tryptophan hydroxylase expression in the adult rat hippocampus. Brain research. vol 1008. issue 1. 2004-06-28. PMID:15081390. |
our results indicate that nnos inhibition upregulates neural plasticity and increases 5-ht in the rat hippocampus, and suggest the existence of regulatory relationships between no, neural plasticity and 5-ht. |
2004-06-28 |
2023-08-12 |
rat |
| Roberto William Invernizzi, Giuseppina Sacchetti, Stefania Parini, Sabrina Acconcia, Rosario Samani. Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors. British journal of pharmacology. vol 139. issue 7. 2004-06-04. PMID:12890707. |
(2) flibanserin at 3 and 10 mg kg(-1) significantly reduced extracellular 5-ht in the prefrontal cortex (by 30 and 45%) and dorsal raphe (35 and 44%), but had no effect on extracellular 5-ht in the ventral hippocampus. |
2004-06-04 |
2023-08-12 |
human |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140183. |
anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by d and 5-ht receptors. |
2004-06-04 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140183. |
the present microdialysis study evaluated the anticonvulsant activity of extracellular hippocampal dopamine (da) and serotonin (5-ht) with concomitant assessment of the possible mutual interactions between these monoamines. |
2004-06-04 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptors. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140183. |
our results suggest that, within a certain concentration range, da and 5-ht contribute independently to the prevention of hippocampal epileptogenesis via, respectively, d(2) and 5-ht(1a) receptor activation. |
2004-06-04 |
2023-08-12 |
rat |
| Clotilde Mannoury la Cour, Naïma Hanoun, Maxette Melfort, René Hen, Klaus-Peter Lesch, Michel Hamon, Laurence Lanfume. GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140188. |
the functional properties of gaba(b) receptors were examined in the dorsal raphe nucleus (drn) and the hippocampus of knock-out mice devoid of the 5-ht transporter (5-htt-/-) or the 5-ht(1a) receptor (5-ht(1a)-/-). |
2004-06-04 |
2023-08-12 |
mouse |
| Clotilde Mannoury la Cour, Naïma Hanoun, Maxette Melfort, René Hen, Klaus-Peter Lesch, Michel Hamon, Laurence Lanfume. GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140188. |
in contrast, gaba(b) receptors appeared functionally intact in the hippocampus of 5-htt-/-, and in both this area and the drn of 5-ht(1a)-knock-out mice. |
2004-06-04 |
2023-08-12 |
mouse |
| M L Leret, V Peinado, L M Suárez, L Tecedor, A Gamallo, J C Gonzále. Role of maternal adrenal glands on the developing serotoninergic and aminoacidergic systems of the postnatal rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 22. issue 2. 2004-06-01. PMID:15036383. |
serotonin levels decreased significantly in males at postnatal day 22 in the hippocampus and cortex. |
2004-06-01 |
2023-08-12 |
rat |
| Eleanor J Bull, Peter H Hutson, Kevin C F Fon. Decreased social behaviour following 3,4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity. Neuropharmacology. vol 46. issue 2. 2004-05-28. PMID:14680758. |
on pnd 92, hippocampal, frontal cortical and striatal 5-hydroxytryptamine (5-ht) was significantly reduced in mdma pre-treated rats by between 16% and 22%, without any accompanying change in [(3)h]paroxetine binding in cortical homogenates. |
2004-05-28 |
2023-08-12 |
rat |