| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Drossopoulou, K Antoniou, E Kitraki, G Papathanasiou, E Papalexi, C Dalla, Z Papadopoulou-Daifot. Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207320. |
moreover, hypothalamic serotonin (5-ht)1a mrna levels were decreased in female rats while in male rats hippocampal 5-ht1a mrna levels were increased. |
2004-10-08 |
2023-08-12 |
rat |
| T P Semenov. [Specifics of monoaminergic regulation of the central nervous system of hibernating animals (Citellus undulatus)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 54. issue 2. 2004-10-05. PMID:15174262. |
biochemical analysis showed that in april the activity of mao a measured with serotonin as a substrate in the hippocampus was 1.8 times (p < 0.05) higher than the activity of mao a with respect to noradrenaline. |
2004-10-05 |
2023-08-12 |
Not clear |
| M-C Pardon, N Hanoun, F Perez-Diaz, C Joubert, J-M Launay, Y Christen, M Hamon, C Cohen-Salmo. Long-term treatment with the antioxidant drug EGb 761 at senescence restored some neurobehavioral effects of chronic ultramild stress exposure seen in young mice. Neurobiology of aging. vol 25. issue 8. 2004-10-04. PMID:15212832. |
the levels of serotonin (5-ht) and its metabolite 5-hydroxyindolacetic acid (5-hiaa) were measured in the brain stem, the cortex, the striatum and the hippocampus; the levels of dopamine (da) and its metabolite dihydroxyphenylacetic acid (dopac) were measured in the brain stem and the striatum. |
2004-10-04 |
2023-08-12 |
mouse |
| Ana García-Osta, Joaquín Del Río, Diana Frechill. Increased CRE-binding activity and tryptophan hydroxylase mRNA expression induced by 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rat frontal cortex but not in the hippocampus. Brain research. Molecular brain research. vol 126. issue 2. 2004-09-30. PMID:15249142. |
a single administration of either 3,4-methylenedioxymethamphetamine (mdma, "ecstasy") or p-chloroamphetamine (pca) produced a rapid and marked reduction of serotonin (5-ht) content in rat frontal cortex and hippocampus. |
2004-09-30 |
2023-08-12 |
rat |
| Milena Koprowska, Maria Krotewicz, Andrzej Romaniuk, Magdalena Strzelczu. Age-related changes in fear behavior and regional brain monoamines distribution in rats. Acta neurobiologiae experimentalis. vol 64. issue 2. 2004-09-30. PMID:15366246. |
differences in fear level assessment based on the time of motionless in the illuminated compartment, time spent in light compartment, number of head dipping from dark to the illuminated compartment and number of returns from dark to the illuminated compartment registered in light/dark transitions test and brain monoamines (na, da, 5-ht) and their metabolites (mhpg, dopac, 5-hiaa) in the hypothalamus, midbrain, amygdala, hippocampus and pons were examined in 3, 12 and 24 months old wistar rats. |
2004-09-30 |
2023-08-12 |
rat |
| Rouzanna L Djavadia. Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals. Acta neurobiologiae experimentalis. vol 64. issue 2. 2004-09-30. PMID:15366252. |
serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals. |
2004-09-30 |
2023-08-12 |
Not clear |
| Julie G Hensler, Clyde W Hodge, David H Overstree. Reduced 5-HT3 receptor binding and lower baseline plus maze anxiety in the alcohol-preferring inbred fawn-hooded rat. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751456. |
the binding of [3h]ly 278584 to 5-ht(3) receptors was significantly reduced in frontal cortex, ca1 region of hippocampus, and in the medial and lateral nuclei of the amygdala of fh/wjd versus aci/n rats. |
2004-09-28 |
2023-08-12 |
rat |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
late onset loss of hippocampal 5-ht and ne is accompanied by increases in bdnf protein expression in mice co-expressing mutant app and ps1. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
transgenic mice expressing both mutant amyloid precursor protein (appswe) and presenilin-1 (ps1deltae9) develop amyloid deposits as early as 4 months of age and preliminary evidence suggests that this may be associated with degenerative changes in serotonin axons innervating the dentate gyrus of the hippocampus. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
in the present investigation, which focused on further delineating the effects of amyloid deposition on hippocampal neurochemistry, decreases in serotonin neurotransmitter levels (-25%) were discovered to be present at 18 months in app+/ps1+ mice, while norepinephrine was reduced in the hippocampus of 12- (-30%) and 18-month-old (-45%) app+/ps1+ double mutants. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
furthermore, in a different model of serotonergic and noradrenergic degeneration, bdnf protein levels were similarly increased in response to depletions in hippocampal serotonin and norepinephrine caused by the chemical neurotoxin 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-nh2-mptp). |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
these findings show that early amyloid deposition in mice expressing mutant human app and ps-1 is associated with a progressive loss of serotonin and norepinephrine neurotransmitter levels in the hippocampus later in life. |
2004-09-24 |
2023-08-12 |
mouse |
| G Csaba, B Knippel, Cs Karabélyos, A Inczefi-Gonda, M Hantos, K Teke. Endorphin excess at weaning durably influences sexual activity, uterine estrogen receptor's binding capacity and brain serotonin level of female rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 36. issue 1. 2004-09-23. PMID:14983405. |
in the present study, single beta-endorphin doses was given to three-week old female rats at 3 microg/animal, and the serotonin in five brain regions (frontal cortex, striatum, hippocampus, hypothalamus and brain stem) and uterine estrogen receptor content were determined, thymic glucocorticoid receptor binding capacity was measured, and sexual behavior was tested at five months of age. |
2004-09-23 |
2023-08-12 |
rat |
| Fengju Bai, Tinggui Yin, Edward M Johnstone, Chen Su, Gabor Varga, Sheila P Little, David L Nelso. Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. European journal of pharmacology. vol 484. issue 2-3. 2004-09-21. PMID:14744596. |
quantitative real-time polymerase chain reaction (qrt-pcr) analysis showed that 5-ht(1e) mrna was present in the guinea pig brain with the greatest abundance in the hippocampus, followed by the olfactory bulb. |
2004-09-21 |
2023-08-12 |
mouse |
| Xiaohua Li, Wawa Zhu, Myoung-Sun Roh, Ari B Friedman, Kelley Rosborough, Richard S Jop. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 8. 2004-09-08. PMID:15039769. |
following administration to mice of d-fenfluramine to stimulate serotonin (5ht) release and reduce its reuptake, and clorgyline to inhibit 5ht catabolism, levels of phospho-ser9-gsk3beta were 300-400% of control levels in the prefrontal cortex, hippocampus, and striatum. |
2004-09-08 |
2023-08-12 |
mouse |
| Katarina Varnäs, Christer Halldin, Håkan Hal. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Human brain mapping. vol 22. issue 3. 2004-09-08. PMID:15195291. |
5-ht(1a) receptor densities were also high in limbic cortical regions (hippocampus, posterior entorhinal cortex, and subcallosal area) compared to the isocortex. |
2004-09-08 |
2023-08-12 |
human |
| Maria Lüttgen, Sven Ove Ogren, Björn Meiste. Chemical identity of 5-HT2A receptor immunoreactive neurons of the rat septal complex and dorsal hippocampus. Brain research. vol 1010. issue 1-2. 2004-09-01. PMID:15126129. |
the results suggest that serotonin acting on 5-ht2a receptors can modulate hippocampal functions via direct actions on hippocampal glutamatergic principal cells and indirectly via actions on hippocampal interneurons with different phenotypes as well as gabaergic and cholinergic septohippocampal neurons. |
2004-09-01 |
2023-08-12 |
rat |
| Toshimi Owashi, Shuji Iritani, Kazuhiro Niizato, Kenji Ikeda, Kunitoshi Kamijim. The distribution of serotonin transporter immunoreactivity in hippocampal formation in monkeys and rats. Brain research. vol 1010. issue 1-2. 2004-09-01. PMID:15126130. |
to elucidate the anatomical distribution of the serotonergic neurotransmitter system, we identified serotonin transporter (5-htt) in the hippocampus of rats and monkeys by immunohistochemistry. |
2004-09-01 |
2023-08-12 |
rat |
| Isabelle Merlet, Philippe Ryvlin, Nicolas Costes, Damien Dufournel, Jean Isnard, Isabelle Faillenot, Karine Ostrowsky, Franck Lavenne, Didier Le Bars, François Mauguièr. Statistical parametric mapping of 5-HT1A receptor binding in temporal lobe epilepsy with hippocampal ictal onset on intracranial EEG. NeuroImage. vol 22. issue 2. 2004-08-19. PMID:15193619. |
in this pet study, we used an antagonist of the 5-ht(1a) receptor, [(18)f]mppf, to assess the extent of 5-ht(1a) receptor binding changes in a group of seven temporal lobe epilepsy (tle) patients with hippocampal ictal onset demonstrated by intracerebral eeg recording. |
2004-08-19 |
2023-08-12 |
human |
| Isabelle Merlet, Philippe Ryvlin, Nicolas Costes, Damien Dufournel, Jean Isnard, Isabelle Faillenot, Karine Ostrowsky, Franck Lavenne, Didier Le Bars, François Mauguièr. Statistical parametric mapping of 5-HT1A receptor binding in temporal lobe epilepsy with hippocampal ictal onset on intracranial EEG. NeuroImage. vol 22. issue 2. 2004-08-19. PMID:15193619. |
these data suggest that in tle patients with hippocampal seizure onset, the decrease in 5-ht(1a) receptor binding partly reflects hippocampal neuronal loss, but is also observed in various regions involved in temporo-limbic epileptogenic networks that appeared normal on mri. |
2004-08-19 |
2023-08-12 |
human |