| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naïma Hanoun, Elisabeth Mocaër, Pierre-Alain Boyer, Michel Hamon, Laurence Lanfume. Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology. vol 47. issue 4. 2005-01-18. PMID:15380370. |
for 21 days) changed the density of 5-ht(1a) receptors and their coupling with g proteins in the drn and the hippocampus in rats. |
2005-01-18 |
2023-08-12 |
rat |
| Naïma Hanoun, Elisabeth Mocaër, Pierre-Alain Boyer, Michel Hamon, Laurence Lanfume. Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology. vol 47. issue 4. 2005-01-18. PMID:15380370. |
moreover, these treatments did not affect the basal electrophysiological characteristics and the responses to 5-ht(1a) receptor stimulation of drn and hippocampal neurons in brain slices. |
2005-01-18 |
2023-08-12 |
rat |
| J P Spencer, J T Brown, J C Richardson, A D Medhurst, S S Sehmi, A R Calver, A D Randal. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. vol 129. issue 1. 2005-01-13. PMID:15489027. |
in the brain, the highest 5-ht(4) receptor densities are found in the limbic system, including the hippocampus and frontal cortex. |
2005-01-13 |
2023-08-12 |
mouse |
| J P Spencer, J T Brown, J C Richardson, A D Medhurst, S S Sehmi, A R Calver, A D Randal. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. vol 129. issue 1. 2005-01-13. PMID:15489027. |
previous electrophysiological studies have shown that the 5-ht(4) agonist, zacopride, can increase population spike amplitude recorded in region ca1 of rat hippocampal slices in a cyclic amp (camp)/camp-dependent protein kinase a-dependent manner. |
2005-01-13 |
2023-08-12 |
mouse |
| J P Spencer, J T Brown, J C Richardson, A D Medhurst, S S Sehmi, A R Calver, A D Randal. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. vol 129. issue 1. 2005-01-13. PMID:15489027. |
we report here that the 5-ht(4) agonist, prucalopride, and the 5-ht(4) partial agonist, sl65.0155, produce a similar effect in rat hippocampal slices and that the specific 5-ht(4) antagonist, gr113808, blocks these effects. |
2005-01-13 |
2023-08-12 |
mouse |
| J P Spencer, J T Brown, J C Richardson, A D Medhurst, S S Sehmi, A R Calver, A D Randal. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. vol 129. issue 1. 2005-01-13. PMID:15489027. |
to investigate the potential use of 5-ht(4) agonists in the treatment of ad, prucalopride was applied to hippocampal slices from a transgenic mouse line that overexpresses the abeta peptide. |
2005-01-13 |
2023-08-12 |
mouse |
| S Morley-Fletcher, M Darnaudéry, E Mocaer, N Froger, L Lanfumey, G Laviola, P Casolini, A R Zuena, Lorenzo Marzano, M Hamon, S Maccar. Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT(1A) receptor mRNA in prenatally stressed rats. Neuropharmacology. vol 47. issue 6. 2005-01-13. PMID:15527818. |
chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-ht(1a) receptor mrna in prenatally stressed rats. |
2005-01-13 |
2023-08-12 |
human |
| S Morley-Fletcher, M Darnaudéry, E Mocaer, N Froger, L Lanfumey, G Laviola, P Casolini, A R Zuena, Lorenzo Marzano, M Hamon, S Maccar. Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT(1A) receptor mRNA in prenatally stressed rats. Neuropharmacology. vol 47. issue 6. 2005-01-13. PMID:15527818. |
glucocorticoid receptor binding sites in the hippocampus were measured and 5-ht(1a) receptor mrna levels in the frontal cortex were also assessed. |
2005-01-13 |
2023-08-12 |
human |
| S Morley-Fletcher, M Darnaudéry, E Mocaer, N Froger, L Lanfumey, G Laviola, P Casolini, A R Zuena, Lorenzo Marzano, M Hamon, S Maccar. Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT(1A) receptor mRNA in prenatally stressed rats. Neuropharmacology. vol 47. issue 6. 2005-01-13. PMID:15527818. |
ps rats were characterised by increased immobility in the forced swim test, reduced hippocampal corticosteroid receptor binding and increased levels of cortical 5-ht(1a) mrna. |
2005-01-13 |
2023-08-12 |
human |
| Jacob Pade Ramsøe Jacobsen, Arne Mør. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain research. vol 1024. issue 1-2. 2005-01-06. PMID:15451381. |
however, all treatments increased 5-ht levels in the hippocampus. |
2005-01-06 |
2023-08-12 |
rat |
| David Dietz, Michael Vogel, Steven Rubin, Timothy Moran, Kathryn Carbone, Mikhail Pletniko. Developmental alterations in serotoninergic neurotransmission in Borna disease virus (BDV)-infected rats: a multidisciplinary analysis. Journal of neurovirology. vol 10. issue 5. 2004-12-30. PMID:15385249. |
the present study sought to provide more insights into postnatal virus-associated alterations in 5-ht neurotransmission by evaluating the density of 5-ht1a receptors in the hippocampus and 5-ht2a receptors in the cortex, regional 5-ht tissue concentrations, behavioral responses to a 5-ht agonist, quipazine, and numbers of neurons in specific subfields of the hippocampus on days 7, 14, and 30 after neonatal bdv infection in lewis rats. |
2004-12-30 |
2023-08-12 |
rat |
| David Dietz, Michael Vogel, Steven Rubin, Timothy Moran, Kathryn Carbone, Mikhail Pletniko. Developmental alterations in serotoninergic neurotransmission in Borna disease virus (BDV)-infected rats: a multidisciplinary analysis. Journal of neurovirology. vol 10. issue 5. 2004-12-30. PMID:15385249. |
neonatal bdv infection was found to be associated with a gradual increase in the density of 5-ht2a and 5-ht1a postsynaptic receptors followed by an elevation of 5-ht contents at both the levels of synaptic terminals (i.e., cortex and hippocampus) and cell bodies (i.e., raphe nuclei). |
2004-12-30 |
2023-08-12 |
rat |
| Margus Tõnissaar, Mari-Anne Philips, Marika Eller, Jaanus Harr. Sociability trait and serotonin metabolism in the rat social interaction test. Neuroscience letters. vol 367. issue 3. 2004-12-17. PMID:15337255. |
when animals were decapitated immediately after a single social interaction test, there was a negative correlation between the social interaction time and 5-hiaa and 5-ht levels in the septum, but not in the frontal cortex or hippocampus. |
2004-12-17 |
2023-08-12 |
rat |
| Mark J Millan, Alain Gobert, Sylvain Roux, Roger Porsolt, Alfredo Meneses, Mirjana Carli, Benjamin Di Cara, Robert Jaffard, Jean-Michel Rivet, Pierre Lestage, Elisabeth Mocaer, Jean-Louis Peglion, Anne Dekeyn. The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis. The Journal of pharmacology and experimental therapeutics. vol 311. issue 1. 2004-12-15. PMID:15146031. |
in a two-platform spatial discrimination task, in which s15535 similarly abrogates cognitive deficits elicited by scopolamine, injection of s15535 (1.0 and 10.0 microg) into dorsal hippocampus blocked amnesic effects of the 5-ht(1a) agonist 8-hydroxy-2-dipropylaminotetralin (0.5 microg). |
2004-12-15 |
2023-08-12 |
mouse |
| David Moranta, Susana Esteban, Jesús A García-Sevill. Differential effects of acute cannabinoid drug treatment, mediated by CB1 receptors, on the in vivo activity of tyrosine and tryptophan hydroxylase in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 5. 2004-12-09. PMID:15064921. |
in contrast, thc and win decreased the synthesis of dopa/dopamine in the corpus striatum (16-37%) and that of 5-htp/5-ht (20-35%) in brain regions enriched in 5-ht (e.g., cerebral cortex and hippocampus). |
2004-12-09 |
2023-08-12 |
rat |
| Y Tohyama, P Sikirić, M Diksi. Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain: alpha-methyl-L-tryptophan autoradiographic measurements. Life sciences. vol 76. issue 3. 2004-12-08. PMID:15531385. |
in the first series of experiments, a single dose treatment of bpc157 (10 microg/kg) administered intraperitoneally 40 min before the alpha-mtrp tracer injection significantly reduced the regional rate of 5-ht synthesis in the dorsal thalamus, hippocampus, lateral geniculate body and hypothalamus. |
2004-12-08 |
2023-08-12 |
rat |
| Shagufta Ahmad, Leslie J Fowler, Peter S Whitto. Effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat. British journal of pharmacology. vol 142. issue 1. 2004-12-07. PMID:15037514. |
effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat. |
2004-12-07 |
2023-08-12 |
rat |
| Shagufta Ahmad, Leslie J Fowler, Peter S Whitto. Effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat. British journal of pharmacology. vol 142. issue 1. 2004-12-07. PMID:15037514. |
we have studied the effects of acute and chronic treatment with the anticonvulsant lamotrigine (ltg) on basal and stimulated extracellular 5-hydroxytryptamine (5-ht), dopamine (da) and their metabolites in the hippocampus of freely moving rats using in vivo microdialysis. |
2004-12-07 |
2023-08-12 |
rat |
| S Singer, S Rossi, S Verzosa, A Hashim, R Lonow, T Cooper, H Sershen, A Lajth. Nicotine-induced changes in neurotransmitter levels in brain areas associated with cognitive function. Neurochemical research. vol 29. issue 9. 2004-12-07. PMID:15453274. |
nicotine-induced changes in the levels of three neurotransmitters, dopamine (da), serotonin (5-ht), norepinepherine (ne), their metabolites, homovanillic acid (hva), dihydroxyphenylacetic acid (dopac), 5-hydroxyindoleacetic acid (5-hiaa), and their precursor, l-dopa, were evaluated in the ventral and dorsal hippocampus (vh and dh), prefrontal and medial temporal cortex (pfc and mtc), and the ventral tegmental area (vta) using in vivo microdialysis in awake, freely moving, male sprague-dawley rats. |
2004-12-07 |
2023-08-12 |
rat |
| Jerrold S Meyer, Mark Grande, Kenneth Johnson, Syed F Al. Neurotoxic effects of MDMA ("ecstasy") administration to neonatal rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 22. issue 5-6. 2004-12-02. PMID:15380826. |
at 9 months, there was no effect of prior mdma exposure on serotonin transporter-immunoreactive fiber density in the hippocampus; however, significant reductions in fiber density were observed in two neocortical areas and a hyperinnervation was found in the caudate-putamen and nucleus accumbens shell. |
2004-12-02 |
2023-08-12 |
rat |