| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S El Ganouni, N Hanoun, C Boni, A Tazi, F Hakkou, M Hamo. Prevention of diazepam withdrawal syndrome by nifedipine-behavioural and neurochemical studies. Pharmacology, biochemistry, and behavior. vol 79. issue 2. 2005-04-19. PMID:15501302. |
biochemical measurements showed that acutely, as well as chronically, administered nifedipine increased 5-ht turnover in the hippocampus of diazepam-treated rats, thereby suggesting that the prevention of diazepam withdrawal-induced anxiogenic behaviour by the calcium antagonist might be underlain by serotoninergic mechanisms. |
2005-04-19 |
2023-08-12 |
rat |
| J Douglas Bremner, Eric Vermette. Neuroanatomical changes associated with pharmacotherapy in posttraumatic stress disorder. Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677402. |
we found that treatment of ptsd patients for a year with the serotonin reuptake inhibitor (ssri) paroxetine resulted in a 5% increase in hippocampal volume and a 35% improvement in verbal declarative memory function. |
2005-04-19 |
2023-08-12 |
Not clear |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Serotonin and stress: protective or malevolent actions in the biobehavioral response to repeated trauma? Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677425. |
pcpa, however, reversed stress-induced hippocampal 5ht(1a) receptor affinity changes, with flx narrowly missing significance. |
2005-04-19 |
2023-08-12 |
rat |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Serotonin and stress: protective or malevolent actions in the biobehavioral response to repeated trauma? Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677425. |
that raised 5ht activity may mediate hippocampal 5ht(1a) receptor changes evoked by stress suggests a bidirectional role for 5ht in the development of ptsd. |
2005-04-19 |
2023-08-12 |
rat |
| Marian Joëls, Els Van Rie. Mineralocorticoid and glucocorticoid receptor-mediated effects on serotonergic transmission in health and disease. Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677436. |
we conclude that prolonged exposure to elevated corticosterone levels attenuates 5-ht responses in the hippocampus through an unresolved mechanism. |
2005-04-19 |
2023-08-12 |
mouse |
| Richard McQuade, Mel M Leitch, Sarah E Gartside, Allan H Youn. Effect of chronic lithium treatment on glucocorticoid and 5-HT1A receptor messenger RNA in hippocampal and dorsal raphe nucleus regions of the rat brain. Journal of psychopharmacology (Oxford, England). vol 18. issue 4. 2005-04-12. PMID:15582915. |
after 28 days of treatment, the expression of mrna for 5-ht(1a) receptors and glucocorticoid receptors in the rat hippocampus and dorsal raphe nucleus was determined by in situ hybridization histochemistry. |
2005-04-12 |
2023-08-12 |
rat |
| Richard McQuade, Mel M Leitch, Sarah E Gartside, Allan H Youn. Effect of chronic lithium treatment on glucocorticoid and 5-HT1A receptor messenger RNA in hippocampal and dorsal raphe nucleus regions of the rat brain. Journal of psychopharmacology (Oxford, England). vol 18. issue 4. 2005-04-12. PMID:15582915. |
chronic administration of lithium decreased mrna coding for post-synaptic 5-ht(1a) receptors in hippocampal subregions but not for somatodentritic 5-ht(1a) receptors in the dorsal raphe nucleus. |
2005-04-12 |
2023-08-12 |
rat |
| Francesco Crespi, Anna C Croce, Sabrina Fiorani, Barbara Masala, Christian Heidbreder, Giovanni Bottirol. In vivo autofluorescence spectrofluorometry of central serotonin. Journal of neuroscience methods. vol 140. issue 1-2. 2005-04-12. PMID:15589336. |
autofluorescence analysis (excitation: 366 nm) on hippocampus homogenates supplied with exogenous 5-ht revealed spectral alterations attributable to changes of endogenous 5-ht levels. |
2005-04-12 |
2023-08-12 |
rat |
| Justin E Aldridge, Armando Meyer, Frederic J Seidler, Theodore A Slotki. Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions. Toxicology and applied pharmacology. vol 203. issue 2. 2005-04-08. PMID:15710174. |
either agent elicited global increases in 5ht receptors and the 5htt in brain regions possessing 5ht cell bodies (midbrain, brainstem) as well as in the hippocampus, which contains 5ht projections. |
2005-04-08 |
2023-08-12 |
human |
| A Tsunemi, M Utsuyama, B K H Seidler, S Kobayashi, K Hirokaw. Age-related decline of brain monoamines in mice is reversed to young level by Japanese herbal medicine. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756935. |
in the aged mice, the levels of norepinepherine, serotonin and their metabolites in the brain were decreased in the cortex, hippocampus and hypothalamus. |
2005-04-08 |
2023-08-12 |
mouse |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. Regional heterogeneity of nicotine effects on neurotransmitters in rat brains in vivo at low doses. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756937. |
nicotine-induced dopamine (da) increase (and increase in da metabolites) and decrease in 5-ht levels at 0.15 mg/kg were significant in the cortex, less so in the hippocampus. |
2005-04-08 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. Regional heterogeneity of nicotine effects on neurotransmitters in rat brains in vivo at low doses. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756937. |
at a low nicotine dose (0.03 mg/kg), the significant changes observed were a decrease in 5-ht in the hippocampus and small increases of da and ne in the prefrontal cortex and of ne in the medial temporal cortex. |
2005-04-08 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. Regional heterogeneity of nicotine effects on neurotransmitters in rat brains in vivo at low doses. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756937. |
we conclude that in areas of cognitive function nicotine-induced da changes are more concentration dependent than changes in ne or 5-ht, and that there are regional differences in neurotransmitter changes induced by nicotine, with ne changes detectable only in the cortex and 5-ht changes only in the hippocampus at a low nicotine dose, indicating significant regional variation in sensitivity to nicotine-induced neurotransmitter changes in brain areas associated with cognitive function. |
2005-04-08 |
2023-08-12 |
rat |
| Laurent Bardin, Marie-Bernadette Assié, Martine Pélissou, Isabelle Royer-Urios, Adrian Newman-Tancredi, Jean-Paul Ribet, François Sautel, Wouter Koek, Francis C Colpaer. Dual, hyperalgesic, and analgesic effects of the high-efficacy 5-hydroxytryptamine 1A (5-HT1A) agonist F 13640 [(3-chloro-4-fluoro-phenyl)-[4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}piperidin-1-yl]methanone, fumaric acid salt]: relationship with 5-HT1A receptor occupancy and kinetic parameters. The Journal of pharmacology and experimental therapeutics. vol 312. issue 3. 2005-04-05. PMID:15528450. |
administration of 0.63 mg/kg was obtained at 15 min and decreased to half its maximal value after about 1 h. the amount of f 13640 collected by means of in vivo microdialysis in hippocampal dialysates could be measured reliably after 0.63 and 2.5 mg/kg, reached its maximum at about 1 h, and fell to half of its maximal value at about 3 h. 5-hydroxytryptamine 1a (5-ht(1a)) receptor occupancy was estimated by ex vivo binding in rat brain sections. |
2005-04-05 |
2023-08-12 |
rat |
| D Bradley Imwalle, Jan-Ake Gustafsson, Emilie F Rissma. Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice. Physiology & behavior. vol 84. issue 1. 2005-04-01. PMID:15642619. |
in addition, erbetako female mice had significantly lower serotonin (5-ht) content than wt littermates in several brain regions including: the bed nucleus of the stria terminalis, preoptic area, and hippocampus. |
2005-04-01 |
2023-08-12 |
mouse |
| Fumihiko Yasun. [Hippocampal serotonin 1A receptor and memory function]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 106. issue 10. 2005-03-29. PMID:15669228. |
[hippocampal serotonin 1a receptor and memory function]. |
2005-03-29 |
2023-08-12 |
human |
| P Houpert, P Lestaevel, C Amourette, B Dhieux, C Bussy, F Paque. Effect of U and 137Cs chronic contamination on dopamine and serotonin metabolism in the central nervous system of the rat. Canadian journal of physiology and pharmacology. vol 82. issue 2. 2005-03-21. PMID:15052298. |
in the striatum, hippocampus, cerebral cortex, thalamus, and cerebellum, the dopamine, serotonin, and catabolite levels were not significantly different between the control rats and rats contaminated by u or 137cs. |
2005-03-21 |
2023-08-12 |
rat |
| T A Kudina, V V Sudnitsyn, E V Kutyreva, V F Kichigin. The serotonin reuptake inhibitor fluoxetine suppresses theta oscillations in the electroencephalogram of the rabbit hippocampus. Neuroscience and behavioral physiology. vol 34. issue 9. 2005-03-21. PMID:15686138. |
the serotonin reuptake inhibitor fluoxetine suppresses theta oscillations in the electroencephalogram of the rabbit hippocampus. |
2005-03-21 |
2023-08-12 |
rabbit |
| T A Kudina, V V Sudnitsyn, E V Kutyreva, V F Kichigin. The serotonin reuptake inhibitor fluoxetine suppresses theta oscillations in the electroencephalogram of the rabbit hippocampus. Neuroscience and behavioral physiology. vol 34. issue 9. 2005-03-21. PMID:15686138. |
experiments on conscious rabbits involved recording of the hippocampal eeg in control conditions and after microinjection of fluoxetine, a serotonin reuptake blocker which increases the levels of this transmitter in the brain. |
2005-03-21 |
2023-08-12 |
rabbit |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
the role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. |
2005-03-17 |
2023-08-12 |
rat |