| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
the role of adrenergic alpha1- and alpha2-adrenoreceptors in augmentation of venlafaxine-induced elevation of extracellular serotonin (5-ht),noradrenaline (na) and dopamine (da) levels in the rat prefrontal cortex (pfc) and hippocampus (hipp) was studied by in vivo microdialysis in anaesthetized rats. |
2005-03-17 |
2023-08-12 |
rat |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
the alpha1-adrenoreceptor antagonist prazosin given alone (0.3 mg/kg, s.c.) induced only a moderate reduction of hippocampal 5-ht and na levels. |
2005-03-17 |
2023-08-12 |
rat |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
the levels of 5-ht increased to 310%, an effect approximately twice the effect on na in the hipp. |
2005-03-17 |
2023-08-12 |
rat |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
pre-treatment with prazosin caused a significant attenuation of the venlafaxine induced 5-ht effect in the pfc, and a moderate increase in da levels in the hipp. |
2005-03-17 |
2023-08-12 |
rat |
| P Weikop, J Kehr, J Scheel-Krüge. The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358984. |
idazoxan had no effect on venlafaxine-induced elevation of extracellular 5-ht levels in either pfc or hipp and prazosin induced a decrease of 5-ht in the pfc. |
2005-03-17 |
2023-08-12 |
rat |
| Veronica Sanchez, Esther O'shea, Kathryn S Saadat, J Martin Elliott, M Isabel Colado, A Richard Gree. Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358986. |
were given 3 h apart to rats housed at 19 degrees c, a dose-dependent acute hyperthermia and long-term loss of 5-ht was observed in several brain regions (hippocampus, cortex and striatum), with an approximate 50% loss following 3 x 4 mg/kg and 65% decrease following 3 x 6 mg/kg. |
2005-03-17 |
2023-08-12 |
rat |
| Veronica Sanchez, Esther O'shea, Kathryn S Saadat, J Martin Elliott, M Isabel Colado, A Richard Gree. Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones. Journal of psychopharmacology (Oxford, England). vol 18. issue 3. 2005-03-17. PMID:15358986. |
a long-term cerebral 5-ht loss of approximately 65% was also detected in both the cortex and hippocampus, but no loss in striatal dopamine content occurred. |
2005-03-17 |
2023-08-12 |
rat |
| Amitabha Chattopadhyay, Md Jafurulla, Shanti Kalipatnapu, Thomas J Pucadyil, Kaleeckal G Harikuma. Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus. Biochemical and biophysical research communications. vol 327. issue 4. 2005-03-14. PMID:15652500. |
we report here that solubilization of the hippocampal 5-ht(1a) receptor by the zwitterionic detergent chaps is accompanied by loss of membrane cholesterol which results in a reduction in specific agonist binding activity and extent of g-protein coupling. |
2005-03-14 |
2023-08-12 |
cattle |
| T Yamato, Y Misumi, S Yamasaki, M Kino, M Aomin. Diabetes mellitus decreases hippocampal release of neurotransmitters: an in vivo microdialysis study of awake, freely moving rats. Diabetes, nutrition & metabolism. vol 17. issue 3. 2005-03-08. PMID:15334789. |
we found that: 1) the basal level of serotonin in the hippocampus was lowest in wbn rats, followed by stz rats, then by c rats. |
2005-03-08 |
2023-08-12 |
rat |
| T J Turner, D J Mokler, J I Luebk. Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies. Neuroscience. vol 129. issue 3. 2005-03-07. PMID:15541891. |
in the present study the effect of 5-ht on gaba release in the hippocampus was characterized using both electrophysiological and biochemical techniques. |
2005-03-07 |
2023-08-12 |
Not clear |
| T J Turner, D J Mokler, J I Luebk. Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies. Neuroscience. vol 129. issue 3. 2005-03-07. PMID:15541891. |
5-ht elicited a burst-like, 6- to 10-fold increase in the frequency of gabaa receptor-mediated inhibitory postsynaptic currents (ipscs) measured with whole-cell voltage-clamp recordings of ca1 neurons in hippocampal slices. |
2005-03-07 |
2023-08-12 |
Not clear |
| T J Turner, D J Mokler, J I Luebk. Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies. Neuroscience. vol 129. issue 3. 2005-03-07. PMID:15541891. |
stimulation of hippocampal synaptosomes with 5-ht resulted in a significant increase in the amount of [3h]gaba released by hyperosmotic saline. |
2005-03-07 |
2023-08-12 |
Not clear |
| Yanxia Liu, Naoya Hamaue, Toru Endo, Masahiko Hirafuji, Masaru Minam. 5-hydroxytryptamine (5-HT) concentrations in the hippocampus, the hypothalamus and the medulla oblongata related to cisplatin-induced pica of rats. Research communications in molecular pathology and pharmacology. vol 113-114. 2005-03-02. PMID:15686111. |
5-hydroxytryptamine (5-ht) concentrations in the hippocampus, the hypothalamus and the medulla oblongata related to cisplatin-induced pica of rats. |
2005-03-02 |
2023-08-12 |
rat |
| Yanxia Liu, Naoya Hamaue, Toru Endo, Masahiko Hirafuji, Masaru Minam. 5-hydroxytryptamine (5-HT) concentrations in the hippocampus, the hypothalamus and the medulla oblongata related to cisplatin-induced pica of rats. Research communications in molecular pathology and pharmacology. vol 113-114. 2005-03-02. PMID:15686111. |
5-ht concentrations in the hippocampus, the medulla oblongata and the hypothalamus significantly increased 72 hours after a single dose administration of cisplatin (5 mg/kg, i.p.) |
2005-03-02 |
2023-08-12 |
rat |
| Kuldip D Dave, Gayani S Fernando, Jennifer L Quinn, John A Harvey, Vincent J Aloy. Serotonin 5-HT2A receptors in the CA1 field of the hippocampus mediate head movements in the rabbit. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15107968. |
serotonin 5-ht2a receptors in the ca1 field of the hippocampus mediate head movements in the rabbit. |
2005-03-01 |
2023-08-12 |
rabbit |
| Elizabeth Scarr, Geoffrey Pavey, David Copolov, Brian Dea. Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474910. |
hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. |
2005-03-01 |
2023-08-12 |
human |
| Elizabeth Scarr, Geoffrey Pavey, David Copolov, Brian Dea. Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474910. |
there is strong evidence that hippocampal 5-hydroxytryptamine (5-ht) systems are affected in schizophrenia and hence we have studied a number of markers of the 5-ht system in hippocampi from subjects with schizophrenia. |
2005-03-01 |
2023-08-12 |
human |
| Elizabeth Scarr, Geoffrey Pavey, David Copolov, Brian Dea. Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474910. |
there were significant decreases in the density of [(3)h]ketanserin binding to the 5-ht(2a) receptor (5-ht(2a)r) in the cornu ammonis (ca) 3 (p=0.006), ca 1 (stratum radiatum p=0.02; pyramidal layer p=0.0008) and subiculum (pyramidal layer p=0.0004), as well as methiothepin-insensitive [(3)h]sumatriptan binding to the 5-ht(1f)r in the ca 1 (p=0.016), stratum radiatum/lacunosum moleculare (p=0.04) and subiculum (p=0.015) from subjects with schizophrenia. |
2005-03-01 |
2023-08-12 |
human |
| A V Sergutina, L M Gershteĭ. [Morphochemical analysis of hippocampus of rats predisposed (August) or resistant (Wistar) to emotional stress]. Morfologiia (Saint Petersburg, Russia). vol 125. issue 2. 2005-02-18. PMID:15232864. |
using quantitative cytochemical methods it was demonstrated that the activities of aminopeptidase, monoaminooxidase (substrates--tryptamine and serotonin), and glutamate dehydrogenase, were lower in the hippocampus of august rats (predisposed to emotional stress) as compared to that one in wistar rats (resistant to emotional stress). |
2005-02-18 |
2023-08-12 |
rat |
| N S Neki, R B Singh, S S Rastog. How brain influences neuro-cardiovascular dysfunction. The Journal of the Association of Physicians of India. vol 52. 2005-02-16. PMID:15636314. |
there is compelling evidence that saturated and total fat and sedentary behaviour can enhance sympathetic activity and increase the secretion of catecholamine, cortisol and serotonin, whereas omega-3 fatty acid supplementation may enhance parasympathetic activity and increase the secretion of acetylcholine in the hippocampus. |
2005-02-16 |
2023-08-12 |
human |