| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucio Schiapparelli, Joaquín Del Río, Diana Frechill. Serotonin 5-HT receptor blockade enhances Ca(2+)/calmodulin-dependent protein kinase II function and membrane expression of AMPA receptor subunits in the rat hippocampus: implications for memory formation. Journal of neurochemistry. vol 94. issue 4. 2005-09-27. PMID:16092936. |
the effects of both antagonists were no longer apparent in rats with a previous 5-ht depletion induced by the tryptophan hydroxylase inhibitor p-chlorophenylalanine (pcpa), suggesting that 5-ht(1a) receptor blockade removes the tonic inhibition of 5-ht through 5-ht(1a) receptor stimulation on excitatory hippocampal neurons, with the consequent increase in pka activity. |
2005-09-27 |
2023-08-12 |
rat |
| Lucio Schiapparelli, Joaquín Del Río, Diana Frechill. Serotonin 5-HT receptor blockade enhances Ca(2+)/calmodulin-dependent protein kinase II function and membrane expression of AMPA receptor subunits in the rat hippocampus: implications for memory formation. Journal of neurochemistry. vol 94. issue 4. 2005-09-27. PMID:16092936. |
this study suggests that blockade of hippocampal 5-ht(1a) receptors favours molecular events critically involved in memory formation, and provides an in vivo molecular basis for the proposed utility of 5-ht(1a) receptor antagonists in the treatment of cognitive disorders. |
2005-09-27 |
2023-08-12 |
rat |
| Julie Koenig, Christine Lazarus, Hélène Jeltsch, Sami Ben Hamida, Céline Riegert, Christian Kelche, Byron C Jones, Jean-Christophe Casse. MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females. Pharmacology, biochemistry, and behavior. vol 81. issue 3. 2005-09-26. PMID:15951008. |
in the surviving females, we observed serotonin depletion in cortex and hippocampus, but catecholaminergic markers were unaltered. |
2005-09-26 |
2023-08-12 |
rat |
| Andrea Gogos, Snezana Kusljic, Maarten van den Buus. 8-OH-DPAT-induced effects on prepulse inhibition: pre- vs. post-synaptic 5-HT1A receptor activation. Pharmacology, biochemistry, and behavior. vol 81. issue 3. 2005-09-26. PMID:15955549. |
a drn lesion caused a significant reduction in 5-ht content in the frontal cortex (70% reduction), striatum (69%) and ventral hippocampus (76%). |
2005-09-26 |
2023-08-12 |
rat |
| Yoshiyuki Watabe, Kanji Yoshimoto, Mitsuoki Eguchi, Shuichi Ued. Degeneration of monoaminergic fibers in the aged micrencephalic rat. Neuroscience letters. vol 385. issue 1. 2005-09-23. PMID:15935555. |
in particular, serotonin levels in the frontal cortex, cingulate cortex and hippocampus of 12-month-old (12 m) mam-treated rats were significantly higher than in corresponding age-matched controls. |
2005-09-23 |
2023-08-12 |
human |
| Ying Xu, Bao-Shan Ku, Hai-Yan Yao, Yan-Hua Lin, Xing Ma, Yong-He Zhang, Xue-Jun L. The effects of curcumin on depressive-like behaviors in mice. European journal of pharmacology. vol 518. issue 1. 2005-09-23. PMID:15987635. |
in addition, the neurochemical assays showed that curcumin produced a marked increase of serotonin and noradrenaline levels at 10 mg/kg in both the frontal cortex and hippocampus. |
2005-09-23 |
2023-08-12 |
mouse |
| Nonna A Otmakhova, Jennifer Lewey, Brent Asrican, John E Lisma. Inhibition of perforant path input to the CA1 region by serotonin and noradrenaline. Journal of neurophysiology. vol 94. issue 2. 2005-09-22. PMID:15888529. |
bath-applied monoamines-dopamine (da), serotonin (5-ht), and noradrenaline (ne)-strongly suppress the perforant path (pp) input to ca1 hippocampal region with very little effect on the schaffer collaterals (sc) input. |
2005-09-22 |
2023-08-12 |
Not clear |
| Shaun Jordan, Ruoyan Chen, Vuk Koprivica, Ronald Hamilton, Richard E Whitehead, Katsura Tottori, Tetsuro Kikuch. In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors. European journal of pharmacology. vol 517. issue 3. 2005-09-12. PMID:15985260. |
opc-14523 also behaved as a partial agonist in its stimulation of [35s]gtpgammas binding to membranes from rat hippocampus (pec50=7.60+/-0.23, emax=41.1% of the effect of 10 microm (+)8-oh-dpat), human frontal cortex (pec50=7.89+/-0.08; emax=64% of the effect of 10 microm (+)8-oh-dpat), and chinese hamster ovary cells expressing cloned human 5-ht1a receptors (pec50=8.0+/-0.11; emax=85.5% of the effect of 10 microm 5-ht), and all of these effects of opc-14523 were blocked by way-100635. |
2005-09-12 |
2023-08-12 |
human |
| Paul D Callaghan, Rodney J Irvine, Lynette C Daw. Differences in the in vivo dynamics of neurotransmitter release and serotonin uptake after acute para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine revealed by chronoamperometry. Neurochemistry international. vol 47. issue 5. 2005-09-08. PMID:15979209. |
to study the effect of these amphetamines on clearance of 5-ht mediated specifically by the sert, clearance of exogenously applied 5-ht was measured in the ca3 region of the hippocampus. |
2005-09-08 |
2023-08-12 |
rat |
| Paul D Callaghan, Rodney J Irvine, Lynette C Daw. Differences in the in vivo dynamics of neurotransmitter release and serotonin uptake after acute para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine revealed by chronoamperometry. Neurochemistry international. vol 47. issue 5. 2005-09-08. PMID:15979209. |
these data demonstrate in vivo (1) brain region variability in the ability of pma and mdma to evoke release of neurotransmitter; (2) that clearance of 5-ht in the striatum is mediated by both the sert and the dat; (3) distinct differences in the amount and nature of neurotransmitter released in the striatum after local application of pma and mdma and (4) that pma is a more efficacious inhibitor of 5-ht clearance in the hippocampus than mdma. |
2005-09-08 |
2023-08-12 |
rat |
| Michael T Williams, Tori L Schaefer, Lisa A Ehrman, Jessica A Able, Gary A Gudelsky, Renu Sah, Charles V Vorhee. 3,4-Methylenedioxymethamphetamine administration on postnatal day 11 in rats increases pituitary-adrenal output and reduces striatal and hippocampal serotonin without altering SERT activity. Brain research. vol 1039. issue 1-2. 2005-08-30. PMID:15781051. |
3,4-methylenedioxymethamphetamine administration on postnatal day 11 in rats increases pituitary-adrenal output and reduces striatal and hippocampal serotonin without altering sert activity. |
2005-08-30 |
2023-08-12 |
rat |
| Michael T Williams, Tori L Schaefer, Lisa A Ehrman, Jessica A Able, Gary A Gudelsky, Renu Sah, Charles V Vorhee. 3,4-Methylenedioxymethamphetamine administration on postnatal day 11 in rats increases pituitary-adrenal output and reduces striatal and hippocampal serotonin without altering SERT activity. Brain research. vol 1039. issue 1-2. 2005-08-30. PMID:15781051. |
we examined monoamines in the hippocampus and striatum and the serotonin transporter in the hippocampus as well as pituitary and adrenal output following administration of mdma (10 mg/kg, 4 times) on postnatal day 11. |
2005-08-30 |
2023-08-12 |
rat |
| Michael T Williams, Tori L Schaefer, Lisa A Ehrman, Jessica A Able, Gary A Gudelsky, Renu Sah, Charles V Vorhee. 3,4-Methylenedioxymethamphetamine administration on postnatal day 11 in rats increases pituitary-adrenal output and reduces striatal and hippocampal serotonin without altering SERT activity. Brain research. vol 1039. issue 1-2. 2005-08-30. PMID:15781051. |
significant depletions in serotonin were evident in the hippocampus 1 h and in the striatum 24 h after the first dose and remained reduced 78 h later. |
2005-08-30 |
2023-08-12 |
rat |
| Sherry A Ferguson, F Javier Cisneros, Bobby J Gough, Syed F Al. Four weeks of oral isotretinoin treatment causes few signs of general toxicity in male and female Sprague-Dawley rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 43. issue 8. 2005-08-30. PMID:15950819. |
at sacrifice, organ weights were collected and concentrations of dopamine (da), serotonin and metabolites were measured in frontal cortex, striatum, hippocampus, and diencephalon. |
2005-08-30 |
2023-08-12 |
human |
| Minke E Jongsma, Fokko J Bosker, Thomas I F H Cremers, Ben H C Westerink, Johan A den Boe. The effect of chronic selective serotonin reuptake inhibitor treatment on serotonin 1B receptor sensitivity and HPA axis activity. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 5. 2005-08-26. PMID:15961207. |
the authors have investigated 5-ht 1b receptor function in prefrontal cortex and dorsal hippocampus as well as the hpa axis response after subchronic (24 h) and chronic (15 days) treatment with the ssri citalopram. |
2005-08-26 |
2023-08-12 |
Not clear |
| Minke E Jongsma, Fokko J Bosker, Thomas I F H Cremers, Ben H C Westerink, Johan A den Boe. The effect of chronic selective serotonin reuptake inhibitor treatment on serotonin 1B receptor sensitivity and HPA axis activity. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 5. 2005-08-26. PMID:15961207. |
basal levels of 5-ht, however, were increased in the dorsal hippocampus following chronic treatment. |
2005-08-26 |
2023-08-12 |
Not clear |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
serotonin was decreased in the hippocampus and increased in the cortex. |
2005-08-24 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
in the hippocampal areas, these antagonists had less significant effect on norepinephrine and serotonin. |
2005-08-24 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
in the hippocampal and cortical areas, the mechanisms of nicotine-induced dopamine increase seem to be similar, but the mechanisms seem to be different for noradrenergic and serotonergic systems, as shown by the fact that nicotine induces no change in norepinephrine and a decrease in serotonin in the hippocampus, while it induces an increase in both in the cortex. |
2005-08-24 |
2023-08-12 |
rat |
| Marjolein Beekman, Cornelia Flachskamm, Astrid C E Linthors. Effects of exposure to a predator on behaviour and serotonergic neurotransmission in different brain regions of C57bl/6N mice. The European journal of neuroscience. vol 21. issue 10. 2005-08-17. PMID:15926930. |
we used a high time-resolution microdialysis method to measure extracellular levels of serotonin (5-hydroxytryptamine, 5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in the hippocampus, prefrontal cortex, lateral septum and caudate putamen of c57bl/6n [corrected] mice, before (08:30-10:30 h), during (10:30-11:00 h) and after exposure (11:00-14:00 h) to a rat. |
2005-08-17 |
2023-08-12 |
mouse |