| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriella Gobbi, Pierre Blie. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides. vol 26. issue 8. 2005-12-21. PMID:16042978. |
it is concluded that nk1 antagonists increase the firing and burst activity of 5-ht neurons, increase burst activity of ne neurons, and modulate postsynaptic transmission at the hippocampus level. |
2005-12-21 |
2023-08-12 |
human |
| Rivelilson Mendes de Freitas, Lissiana M V Aguiar, Silvânia M M Vasconcelos, Francisca C F Sousa, Glauce S B Viana, Marta M F Fontele. Modifications in muscarinic, dopaminergic and serotonergic receptors concentrations in the hippocampus and striatum of epileptic rats. Life sciences. vol 78. issue 3. 2005-12-20. PMID:16137708. |
the present study was undertaken in order to investigate the muscarinic (m(1)), dopaminergic (d(1) and d(2)) and serotonergic (5-ht(2)) receptors densities in hippocampus and striatum of wistar rats after status epilepticus (se) induced by pilocarpine. |
2005-12-20 |
2023-08-12 |
rat |
| Rivelilson Mendes de Freitas, Lissiana M V Aguiar, Silvânia M M Vasconcelos, Francisca C F Sousa, Glauce S B Viana, Marta M F Fontele. Modifications in muscarinic, dopaminergic and serotonergic receptors concentrations in the hippocampus and striatum of epileptic rats. Life sciences. vol 78. issue 3. 2005-12-20. PMID:16137708. |
in both areas the 5-ht(2) receptor density remained unaltered, but a reduction (50%) and an increase (15%) in the k(d) values were detected in striatum and hippocampus, respectively. |
2005-12-20 |
2023-08-12 |
rat |
| A Richard Green, Esther O'Shea, Kathryn S Saadat, J Martin Elliott, M Isabel Colad. Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures. British journal of pharmacology. vol 146. issue 2. 2005-12-09. PMID:15997230. |
mdma (5 mg kg(-1)) did not alter the tail temperature of rats at ta 15 degrees c, but decreased the tail temperature of rats at ta 30 degrees c. a neurotoxic dose of mdma (three doses of 5 mg kg(-1) given 3 h apart) decreased cortical and hippocampal 5-ht content by approximately 30% 7 days later. |
2005-12-09 |
2023-08-12 |
rat |
| Altaf S Darvesh, Gary A Gudelsk. Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT. Brain research. vol 1056. issue 2. 2005-12-07. PMID:16098955. |
in the present study, the effect of supplementing energy substrates was examined on the long-term depletion of striatal 5-ht and dopamine produced by the local perfusion of mdma (100 microm) and malonate (100 mm) and the depletion of striatal and hippocampal 5-ht concentrations produced by the systemic administration of mdma (10 mg/kg i.p. |
2005-12-07 |
2023-08-12 |
Not clear |
| Altaf S Darvesh, Gary A Gudelsk. Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT. Brain research. vol 1056. issue 2. 2005-12-07. PMID:16098955. |
perfusion of nicotinamide or ubiquinone (100 microm) also attenuated the depletion of 5-ht in the striatum and hippocampus produced by the systemic administration of mdma. |
2005-12-07 |
2023-08-12 |
Not clear |
| Jean-Christophe Cassel, Céline Riegert, Susanne Rutz, Julie Koenig, Katharina Rothmaier, Brigitte Cosquer, Christine Lazarus, Anja Birthelmer, Hélène Jeltsch, Byron C Jones, Rolf Jackisc. Ethanol, 3,4-methylenedioxymethamphetamine (ecstasy) and their combination: long-term behavioral, neurochemical and neuropharmacological effects in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 10. 2005-11-29. PMID:15785779. |
subsequently, we measured cortical, striatal, septal, and hippocampal monoamines (last mdma injection-euthanasia delay: 20 days), or electrically evoked release of serotonin (5-ht) in cortical and hippocampal slices, and its modulation in the presence of cp 93,129 (3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrollo[3,2-b]pyrid-5-one) or methiotepin (last mdma injection-euthanasia delays: 3-6 weeks). |
2005-11-29 |
2023-08-12 |
rat |
| Jean-Christophe Cassel, Céline Riegert, Susanne Rutz, Julie Koenig, Katharina Rothmaier, Brigitte Cosquer, Christine Lazarus, Anja Birthelmer, Hélène Jeltsch, Byron C Jones, Rolf Jackisc. Ethanol, 3,4-methylenedioxymethamphetamine (ecstasy) and their combination: long-term behavioral, neurochemical and neuropharmacological effects in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 10. 2005-11-29. PMID:15785779. |
in hippocampal slices from rats given ethanol and mdma, the cp 93,129-induced inhibition and methiotepin-induced facilitation of 5-ht release were stronger and weaker, respectively, than in the other groups. |
2005-11-29 |
2023-08-12 |
rat |
| Jean-Christophe Cassel, Céline Riegert, Susanne Rutz, Julie Koenig, Katharina Rothmaier, Brigitte Cosquer, Christine Lazarus, Anja Birthelmer, Hélène Jeltsch, Byron C Jones, Rolf Jackisc. Ethanol, 3,4-methylenedioxymethamphetamine (ecstasy) and their combination: long-term behavioral, neurochemical and neuropharmacological effects in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 10. 2005-11-29. PMID:15785779. |
whereas the drug combination produced the same behavioral and neurochemical effects as mdma alone, our neuropharmacological results suggest that mdma-etoh interactions may have specific long-term consequences on presynaptic modulation of hippocampal 5-ht release, but not necessarily related to mdma-induced depletion of 5-ht. |
2005-11-29 |
2023-08-12 |
rat |
| Renato Corradetti, Boris Mlinar, Chiara Falsini, Anna Maria Pugliese, Antonio Cilia, Carla Destefani, Rodolfo Test. Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15951403. |
differential effects of the 5-hydroxytryptamine (5-ht)1a receptor inverse agonists rec 27/0224 and rec 27/0074 on electrophysiological responses to 5-ht1a receptor activation in rat dorsal raphe nucleus and hippocampus in vitro. |
2005-11-28 |
2023-08-12 |
human |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
contrasting contribution of 5-hydroxytryptamine 1a receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. |
2005-11-28 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
we employed microdialysis coupled to high pressure liquid chromatography with electrochemical detection to examine 5-ht1a receptor activation in the modulation of extracellular dopamine in medial prefrontal cortex and serotonin in hippocampus of freely moving rats. |
2005-11-28 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
hippocampal 5-ht was decreased by bifeprunox, ssr181507, slv313, sarizotan, and nemonapride, effects similar to those seen with the 5-ht1a agonist, (+)-8-hydroxy-2-(di-n-propylamino)tetralin [(+)8-oh-dpat], consistent with activation of 5-ht1a autoreceptors. |
2005-11-28 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
in contrast, haloperidol, risperidone, clozapine, olanzapine, ziprasidone, and aripiprazole did not significantly modify hippocampal serotonin levels. |
2005-11-28 |
2023-08-12 |
rat |
| J M Johns, P W Joyner, M S McMurray, D L Elliott, V E Hofler, C L Middleton, K Knupp, K W Greenhill, L M Lomas, C H Walke. The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996723. |
dopamine uptake inhibition appears to have a strong effect on hippocampal oxytocin levels, while receptor dynamics may be more strongly affected by serotonin uptake inhibition. |
2005-11-28 |
2023-08-12 |
rat |
| Silvia Racca, Angela Spaccamiglio, Paola Esculapio, Giuliana Abbadessa, Luigi Cangemi, Francesco DiCarlo, Paolo Portaleon. Effects of swim stress and alpha-MSH acute pre-treatment on brain 5-HT transporter and corticosterone receptor. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:16023186. |
taking all together these data, we investigated the effects of the fst exposure and the effects of pre-treatment with alpha-msh on cortical synaptosomal serotonin transporter (sert) activity, corticosterone (cort) plasma levels and on glucocorticoid receptor (gr) occupancy and expression in rat hippocampus. |
2005-11-28 |
2023-08-12 |
rat |
| Yamuna Devi Paila, Thomas J Pucadyil, Amitabha Chattopadhya. The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1A receptor. Molecular membrane biology. vol 22. issue 3. 2005-11-22. PMID:16096266. |
the cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1a receptor. |
2005-11-22 |
2023-08-12 |
cattle |
| Yamuna Devi Paila, Thomas J Pucadyil, Amitabha Chattopadhya. The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1A receptor. Molecular membrane biology. vol 22. issue 3. 2005-11-22. PMID:16096266. |
we have examined the modulatory role of cholesterol on the ligand binding of the bovine hippocampal 5-ht(1a) receptor by cholesterol complexation in native membranes using digitonin. |
2005-11-22 |
2023-08-12 |
cattle |
| Yamuna Devi Paila, Thomas J Pucadyil, Amitabha Chattopadhya. The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1A receptor. Molecular membrane biology. vol 22. issue 3. 2005-11-22. PMID:16096266. |
complexation of cholesterol from bovine hippocampal membranes using digitonin results in a concentration-dependent reduction in specific binding of the agonist 8-oh-dpat and antagonist p-mppf to 5-ht(1a) receptors. |
2005-11-22 |
2023-08-12 |
cattle |
| Joanna I Udo de Haes, Thomas I F H Cremers, Fokko-J Bosker, Folkert Postema, Theodora D Tiemersma-Wegman, Johan A den Boe. Effect of increased serotonin levels on [18F]MPPF binding in rat brain: fenfluramine vs the combination of citalopram and ketanserin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 9. 2005-11-07. PMID:15827572. |
fenfluramine treatment resulted in a 30-fold increase in extracellular 5-ht levels in the ventral hippocampus and induced a significant reduction of [18f]mppf binding in the frontal cortex, hypothalamus, amygdala, and hippocampus. |
2005-11-07 |
2023-08-12 |
rat |