| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric Dailly, Franck Chenu, Benoit Petit-Demoulière, Michel Bouri. Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins. Journal of neuroscience methods. vol 150. issue 1. 2006-04-03. PMID:16098600. |
the aim of this work is to define neurotoxins doses to have efficient and specific depletion of noradrenaline (na), serotonin (5-ht) neurotransmission in cortex, striatum, hippocampus and hypothalamus of swiss mice after intraperitoneal administration of, respectively, n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine hydrochloride (dsp-4) and para-chlorophenylalanine methyl ester hydrochloride (pcpa). |
2006-04-03 |
2023-08-12 |
mouse |
| Eric Dailly, Franck Chenu, Benoit Petit-Demoulière, Michel Bouri. Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins. Journal of neuroscience methods. vol 150. issue 1. 2006-04-03. PMID:16098600. |
the minimal single dose necessary to produce a highly significant decrease of na levels (p<0.01 in comparison with control group) in hypothalamus (-44%), hippocampus (-91%), striatum (-40%) and cortex (-68%) was 50mg/kg but da and 5-ht levels were modified, respectively, in hypothalamus and striatum. |
2006-04-03 |
2023-08-12 |
mouse |
| Joseph M Breier, Michael G Bankson, Bryan K Yamamot. L-tyrosine contributes to (+)-3,4-methylenedioxymethamphetamine-induced serotonin depletions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399699. |
the local infusion of l-tyrosine into the striatum or hippocampus during mdma administration potentiated the acute increase in extracellular da and the long-term depletion of 5-ht after mdma. |
2006-03-31 |
2023-08-12 |
Not clear |
| Joseph M Breier, Michael G Bankson, Bryan K Yamamot. L-tyrosine contributes to (+)-3,4-methylenedioxymethamphetamine-induced serotonin depletions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399699. |
in contrast, the reverse dialysis of the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine into the hippocampus did not affect mdma-induced increases in extracellular da or the long-term depletion in 5-ht. |
2006-03-31 |
2023-08-12 |
Not clear |
| Ouissame Mnie-Filali, Mostafa El Mansari, Agnès Espana, Connie Sànchez, Nasser Haddjer. Allosteric modulation of the effects of the 5-HT reuptake inhibitor escitalopram on the rat hippocampal synaptic plasticity. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16330146. |
allosteric modulation of the effects of the 5-ht reuptake inhibitor escitalopram on the rat hippocampal synaptic plasticity. |
2006-03-29 |
2023-08-12 |
rat |
| Ouissame Mnie-Filali, Mostafa El Mansari, Agnès Espana, Connie Sànchez, Nasser Haddjer. Allosteric modulation of the effects of the 5-HT reuptake inhibitor escitalopram on the rat hippocampal synaptic plasticity. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16330146. |
the present in vivo electrophysiological studies in anesthetized rat were undertaken to assess the effects of the selective serotonin (5-ht) reuptake inhibitor (ssri) escitalopram alone or in combination with the r-citalopram (the s- and r-enantiomers of citalopram), on both long-term potentiation (ltp) in the ca(1) region of dorsal hippocampus and spontaneous firing activity of dorsal raphe (dr) 5-ht neurons. |
2006-03-29 |
2023-08-12 |
rat |
| Annie Daszuta, Mounira Ban, Amélie Soumier, Micheline Hery, Elisabeth Mocae. [Depression and neuroplasticity: implication of serotoninergic systems]. Therapie. vol 60. issue 5. 2006-03-28. PMID:16433011. |
interestingly, serotonergic (5-ht) systems play a major role both as antidepressants and by increasing hippocampal neurogenesis through various receptor subtypes. |
2006-03-28 |
2023-08-12 |
Not clear |
| Alain Gardie. [Mechanism of action of antidepressant drugs: importance of genetically modified mice in the pharmacological in vivo approach]. Therapie. vol 60. issue 5. 2006-03-28. PMID:16433012. |
thus, we found that indirect activation of 5-ht1b autoreceptors limits the effects of ssris on dialysate 5-ht levels at serotonergic nerve terminals such as the ventral hippocampus. |
2006-03-28 |
2023-08-12 |
mouse |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
increased psychophysiological resistance to chronic stress has been related to increased 5-ht release in the dorsal hippocampus. |
2006-03-14 |
2023-08-12 |
Not clear |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
this study investigated the changes in 5-ht release and turnover in the hippocampus evoked by acute and repeated exposure to an inescapable stressor, an elevated open platform, and compared them to the changes evoked in the frontal cortex. |
2006-03-14 |
2023-08-12 |
Not clear |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
repeated exposure to the stressor for 5 or 10 occasions increased 5-ht turnover in the hippocampus. |
2006-03-14 |
2023-08-12 |
Not clear |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
microdialysis studies showed that acute stress increased 5-ht overflow in prefrontal cortex but not dorsal hippocampus whereas repeated daily (10 days) exposure to the stressor increased basal extracellular 5-ht in the dorsal hippocampus, but not the prefrontal cortex. |
2006-03-14 |
2023-08-12 |
Not clear |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
it is concluded that acute exposure to this form of inescapable stress selectively stimulates the 5-ht projections to the frontal cortex; repeated stress elicits a sustained increase in 5-ht release and turnover in the hippocampus. |
2006-03-14 |
2023-08-12 |
Not clear |
| J D Storey, D A F Robertson, J E Beattie, I C Reid, S N Mitchell, D J K Balfou. Behavioural and neurochemical responses evoked by repeated exposure to an elevated open platform. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16150498. |
the data are consistent with the hypothesis that increased 5-ht release in the hippocampus may be implicated in the mechanisms underlying habituation to inescapable stress. |
2006-03-14 |
2023-08-12 |
Not clear |
| K Tokumo, N Tamura, T Hirai, H Nishi. Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16214236. |
in the neurochemical study, diazepam had no effect on the content of 5-ht and its metabolite in the brain cortex or hippocampus. |
2006-03-14 |
2023-08-12 |
mouse |
| K Tokumo, N Tamura, T Hirai, H Nishi. Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16214236. |
on the other hand, tfmpp inhibited the 5-ht turnover rate accompanied by the elevation of the 5-ht content and reduction of the 5-hiaa content in the brain cortex and hippocampus. |
2006-03-14 |
2023-08-12 |
mouse |
| K Tokumo, N Tamura, T Hirai, H Nishi. Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain. Behavioural brain research. vol 166. issue 2. 2006-03-14. PMID:16214236. |
(z)-3-hexenol significantly increased the 5-ht content without affecting the 5-hiaa content or the 5-ht turnover rate in the brain cortex or hippocampus. |
2006-03-14 |
2023-08-12 |
mouse |
| Dong-Kyu Kim, Teresa J Tolliver, Su-Jan Huang, Bradley J Martin, Anne M Andrews, Christine Wichems, Andrew Holmes, Klaus-Peter Lesch, Dennis L Murph. Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology. vol 49. issue 6. 2006-03-10. PMID:16183083. |
to evaluate the consequences of inactivation of the serotonin transporter (sert) gene on 5-ht homeostasis and function, 5-ht synthesis and turnover rates were measured using the decarboxylase inhibition method in multiple brain regions (frontal cortex, striatum, brainstem, hippocampus and hypothalamus) from mice with a genetic disruption of sert. |
2006-03-10 |
2023-08-12 |
mouse |
| Franck Chenu, Michel Bouri. Potentiation of antidepressant-like activity with lithium: mechanism involved. Current drug targets. vol 7. issue 2. 2006-03-10. PMID:16475957. |
based on neurobiochemical and behavioral results we tried to better understand its mechanism of action and we concluded that effect of lithium on 5-ht neurotransmission could be linked to a partial agonist activity on 5-ht1b autoreceptors, or to a modulatory activity on these receptors, located in the cortical area in the case of a short term treatment, or in the hippocampus in the case of a long term treatment. |
2006-03-10 |
2023-08-12 |
Not clear |
| Berna Terzioğlu, Cenk Aypak, Hasan Raci Yananli, Esra Küçükibrahimoğlu, Cihan Yurdaydin, M Zafer Göre. 5-hydroxytryptamine release in the anterior hypothalamic and the hippocampal areas of cholestatic rats. Life sciences. vol 78. issue 10. 2006-03-09. PMID:16185717. |
5-hydroxytryptamine release in the anterior hypothalamic and the hippocampal areas of cholestatic rats. |
2006-03-09 |
2023-08-12 |
rat |