| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeanine I H Keuker, Jan N Keijser, Csaba Nyakas, Paul G M Luiten, Eberhard Fuch. Aging is accompanied by a subfield-specific reduction of serotonergic fibers in the tree shrew hippocampal formation. Journal of chemical neuroanatomy. vol 30. issue 4. 2006-01-13. PMID:16169187. |
a partial depletion of serotonin in the hippocampal formation, as can be expected from our current observations, will probably have an impact on the functioning of hippocampal principal neurons. |
2006-01-13 |
2023-08-12 |
rat |
| Grzegorz Kuballa, Przemysław Nowak, Łukasz Labus, Aleksandra Bortel, Joanna Dabrowska, Marek Swoboda, Adam Kwieciński, Richard M Kostrzewa, Ryszard Bru. Central effects of nafadotride, a dopamine D3 receptor antagonist, in rats. Comparison with haloperidol and clozapine. Pharmacological reports : PR. vol 57. issue 2. 2006-01-12. PMID:15886414. |
by hplc/ed methods, we determined the effects of the examined antagonists on the levels of biogenic amines in striatum and hippocampus: dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt), 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa) and noradrenaline (na). |
2006-01-12 |
2023-08-12 |
rat |
| Grzegorz Kuballa, Przemysław Nowak, Łukasz Labus, Aleksandra Bortel, Joanna Dabrowska, Marek Swoboda, Adam Kwieciński, Richard M Kostrzewa, Ryszard Bru. Central effects of nafadotride, a dopamine D3 receptor antagonist, in rats. Comparison with haloperidol and clozapine. Pharmacological reports : PR. vol 57. issue 2. 2006-01-12. PMID:15886414. |
additionally, da and 5-ht synthesis rate was determined in striatum and 5-ht in hippocampus. |
2006-01-12 |
2023-08-12 |
rat |
| Monika Palchaudhuri, Gabriele Flügg. 5-HT1A receptor expression in pyramidal neurons of cortical and limbic brain regions. Cell and tissue research. vol 321. issue 2. 2006-01-12. PMID:15947971. |
principal neurons in hippocampal region ca1 expressed 5-ht(1a) receptor mrna, and (3)h-8-oh-dpat labeled both the stratum oriens and stratum radiatum. |
2006-01-12 |
2023-08-12 |
Not clear |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. |
2006-01-10 |
2023-08-12 |
rat |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
studies have shown that exposure of rats to animal tests of anxiety increases extracellular 5-ht in the cortex or hippocampus determined by in vivo microdialysis. |
2006-01-10 |
2023-08-12 |
rat |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
to discriminate whether this increase is caused by the aversive conditions of an animal test for anxiety or by an unconditioned stressor evoking mainly arousal, the present study investigates the effects of an unconditioned acoustic stimulus and exposure to the elevated plus maze (x-maze), respectively, on the release of 5-ht in the ventral hippocampus compared with hippocampal 5-ht release in the home cage and in a non-aversive unfamiliar environment in freely moving rats. |
2006-01-10 |
2023-08-12 |
rat |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
our results showed a distinct pattern of 5-ht release in the ventral hippocampus depending on the stimulus used. |
2006-01-10 |
2023-08-12 |
rat |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
exposure to the x-maze for 20 min was accompanied by an 'anxious' behaviour in the rats and increased extracellular 5-ht to 165% of basal release, whereas exposure to a less aversive 'deactivated' plus maze (115+/-6%) or to white noise for 20 min in the familiar surroundings of the home cage (98+/-6%) did not change hippocampal 5-ht release significantly, despite similar behavioural activation indicated by increased locomotor activity. |
2006-01-10 |
2023-08-12 |
rat |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
the results suggest a close relationship between anxiety-related behaviour, but not arousal/non-specific behavioural activation, and 5-ht release in the ventral hippocampus. |
2006-01-10 |
2023-08-12 |
rat |
| Krzysztof Tokarski, Agnieszka Zahorodna, Bartosz Bobula, Malgorzata Grzegorzewska, Patrycja Pitra, Grzegorz Hes. Repeated administration of citalopram and imipramine alters the responsiveness of rat hippocampal circuitry to the activation of 5-HT7 receptors. European journal of pharmacology. vol 524. issue 1-3. 2006-01-05. PMID:16253236. |
the effects of a selective serotonin reuptake inhibitor, citalopram, and a tricyclic antidepressant drug, imipramine, administered repetitively for 14 days, were investigated ex vivo in rat hippocampal slices. |
2006-01-05 |
2023-08-12 |
rat |
| Krzysztof Tokarski, Agnieszka Zahorodna, Bartosz Bobula, Malgorzata Grzegorzewska, Patrycja Pitra, Grzegorz Hes. Repeated administration of citalopram and imipramine alters the responsiveness of rat hippocampal circuitry to the activation of 5-HT7 receptors. European journal of pharmacology. vol 524. issue 1-3. 2006-01-05. PMID:16253236. |
repeated treatment with citalopram or imipramine resulted in an attenuation of the excitatory effects of the activation of hippocampal 5-ht(7) receptor. |
2006-01-05 |
2023-08-12 |
rat |
| G F Molodtsov. Changes in serotonin metabolism in the rat brain on presentation of a habituated stimulus. Neuroscience and behavioral physiology. vol 35. issue 6. 2006-01-05. PMID:16342611. |
these experiments showed that presentation of the habituated stimulus was accompanied by increases in serotonin metabolism and the active transport of its metabolite in the amygdaloid complex, striatum, and midbrain, with no significant changes in the hippocampus or prefrontal cortex. |
2006-01-05 |
2023-08-12 |
rat |
| Yuji Odagaki, Ryoichi Toyoshim. Detailed pharmacological characterization of 5-HT1A-receptor-mediated [35S]GTP gamma S binding in rat hippocampal membranes. Journal of pharmacological sciences. vol 98. issue 1. 2005-12-30. PMID:15888961. |
although caution should be paid especially to the apparent intrinsic activities susceptible to the assay conditions, this method appears useful to investigate functional coupling between 5-ht(1a) receptors and their coupled g proteins in native hippocampal membranes. |
2005-12-30 |
2023-08-12 |
rat |
| Janusz Szyndler, Teresa Wierzba-Bobrowicz, Anna Skórzewska, Piotr Maciejak, Jerzy Walkowiak, Waldemar Lechowicz, Danuta Turzyńska, Andrzej Bidziński, Adam Płaźni. Behavioral, biochemical and histological studies in a model of pilocarpine-induced spontaneous recurrent seizures. Pharmacology, biochemistry, and behavior. vol 81. issue 1. 2005-12-30. PMID:15894059. |
moreover, neurotransmitters' (dopamine, serotonin and their metabolites) concentration was measured in selected brain structures involved in emotional and motor processing (hippocampus, frontal cortex and striatum). |
2005-12-30 |
2023-08-12 |
rat |
| Virginia L Lucaites, Joseph H Krushinski, John M Schaus, James E Audia, David L Nelso. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. II. Autoradiographic localization in rat, guinea pig, monkey and human brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 3. 2005-12-23. PMID:15900511. |
specific 5-ht(1f) receptor binding in rat brain was found in layers 4-5 of all cortical regions examined, as well as olfactory bulb and tubercle, nucleus accumbens, caudate putamen, parafascicular nucleus of the thalamus, medial mammillary nucleus, the ca3 region of the hippocampus, subiculum, and several amygdaloid nuclei. |
2005-12-23 |
2023-08-12 |
human |
| G-J Huang, J Herber. The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16129565. |
micro-injection of the 5-ht neurotoxin 5,7-dihydroxytryptamine into the fimbria-fornix (3.0 microg/side) and the cingulate bundle (1.8 microg/side) depleted hippocampal 5-ht locally but did not change cell proliferation 3 weeks after the surgery. |
2005-12-22 |
2023-08-12 |
rat |
| G-J Huang, J Herber. The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16129565. |
these results suggest that 5-ht(1a) modulates cell proliferation in the hippocampus by a direct post-synaptic effect. |
2005-12-22 |
2023-08-12 |
rat |
| Z Ma, R E Strecker, J T McKenna, M M Thakkar, R W McCarley, R Ta. Effects on serotonin of (-)nicotine and dimethylphenylpiperazinium in the dorsal raphe and nucleus accumbens of freely behaving rats. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16154286. |
however, dmpp was reported to increase 5-ht using non-nachr mechanism [lendvai b, sershen h, lajtha a, santha e, baranyi m, vizi es (1996) differential mechanisms involved in the effect of nicotinic agonists dmpp and lobeline to release [3h]5-ht from rat hippocampal slices. |
2005-12-22 |
2023-08-12 |
rat |
| Gabriella Gobbi, Pierre Blie. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides. vol 26. issue 8. 2005-12-21. PMID:16042978. |
since antidepressant and anxiolytic drugs act mainly by enhancing serotonin (5-ht) and norepinephrine (ne) neurotransmission in forebrain areas, the main focus of the present review is to critically examine the electrophysiological effects of nk1 receptor antagonists on serotoninergic and noradrenergic neurons, and then hippocampal neurons. |
2005-12-21 |
2023-08-12 |
human |