| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna I Udo de Haes, Thomas I F H Cremers, Fokko-J Bosker, Folkert Postema, Theodora D Tiemersma-Wegman, Johan A den Boe. Effect of increased serotonin levels on [18F]MPPF binding in rat brain: fenfluramine vs the combination of citalopram and ketanserin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 9. 2005-11-07. PMID:15827572. |
the microdialysis results showed a 10-fold 5-ht increase in the ventral hippocampus after combined administration of ketanserin and citalopram. |
2005-11-07 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine. Neuroscience letters. vol 390. issue 1. 2005-11-07. PMID:16139430. |
hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine. |
2005-11-07 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine. Neuroscience letters. vol 390. issue 1. 2005-11-07. PMID:16139430. |
we recently showed that dopamine (da) and serotonin (5-ht) exert anticonvulsant effects against limbic seizures in rats mediated by hippocampal d(2) and 5-ht(1a) receptor stimulation. |
2005-11-07 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine. Neuroscience letters. vol 390. issue 1. 2005-11-07. PMID:16139430. |
the anticonvulsant threshold concentrations for oxcarbazepine (100 microm) and 10,11-dihydro-10-hydroxycarbamazepine (250 microm) were associated with, respectively, 140 and 205% increases in hippocampal dopamine and 288 and 176% increases in serotonin concentrations. |
2005-11-07 |
2023-08-12 |
rat |
| Martha A Cohen, Matthew R Skelton, Tori L Schaefer, Gary A Gudelsky, Charles V Vorhees, Michael T William. Learning and memory after neonatal exposure to 3,4-methylenedioxymethamphetamine (ecstasy) in rats: interaction with exposure in adulthood. Synapse (New York, N.Y.). vol 57. issue 3. 2005-10-27. PMID:15945064. |
other tests (elevated zero maze, cwm, nor, and open-field activity) did not show an interaction, nor did hippocampal concentrations of serotonin or dopamine. |
2005-10-27 |
2023-08-12 |
rat |
| L E Schechter, D L Smith, S Rosenzweig-Lipson, S J Sukoff, L A Dawson, K Marquis, D Jones, M Piesla, T Andree, S Nawoschik, J A Harder, M D Womack, J Buccafusco, A V Terry, B Hoebel, P Rada, M Kelly, M Abou-Gharbia, J E Barrett, W Childer. Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. The Journal of pharmacology and experimental therapeutics. vol 314. issue 3. 2005-10-21. PMID:15951399. |
lecozotan (sra-333): a selective serotonin 1a receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. |
2005-10-21 |
2023-08-12 |
monkey |
| L E Schechter, D L Smith, S Rosenzweig-Lipson, S J Sukoff, L A Dawson, K Marquis, D Jones, M Piesla, T Andree, S Nawoschik, J A Harder, M D Womack, J Buccafusco, A V Terry, B Hoebel, P Rada, M Kelly, M Abou-Gharbia, J E Barrett, W Childer. Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. The Journal of pharmacology and experimental therapeutics. vol 314. issue 3. 2005-10-21. PMID:15951399. |
using in vivo microdialysis, lecozotan (0.3 mg/kg s.c.) antagonized the decrease in hippocampal extracellular 5-ht induced by a challenge dose (0.3 mg/kg s.c.) of 8-hydroxy-2-dipropylaminotetralin (8-oh-dpat) and had no effects alone at doses 10-fold higher. |
2005-10-21 |
2023-08-12 |
monkey |
| Yemin Wang, Lingdong Kong, Yumei Che. Behavioural and biochemical effects of fractions prepared from Banxia Houpu decoction in depression models in mice. Phytotherapy research : PTR. vol 19. issue 6. 2005-10-20. PMID:16114088. |
we-1, as well as we-1-3, was found to increase serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) levels in mouse hippocampus and striatum, the activities of we-1 and we-1-3 were much stronger than that of fluoxetine. |
2005-10-20 |
2023-08-12 |
mouse |
| Snezana Kusljic, Jan Brosda, Trevor R Norman, Maarten van den Buus. Brain serotonin depletion by lesions of the median raphe nucleus enhances the psychotomimetic action of phencyclidine, but not dizocilpine (MK-801), in rats. Brain research. vol 1049. issue 2. 2005-10-19. PMID:15953591. |
mrn lesions caused serotonin depletion in the dorsal hippocampus, whereas drn lesions caused serotonin depletion in the frontal cortex, striatum and ventral hippocampus. |
2005-10-19 |
2023-08-12 |
rat |
| H Ishiwata, T Shiga, N Okad. Selective serotonin reuptake inhibitor treatment of early postnatal mice reverses their prenatal stress-induced brain dysfunction. Neuroscience. vol 133. issue 4. 2005-10-11. PMID:15927403. |
we previously reported that the serotonin concentration and synaptic density in the hippocampus were reduced following prenatal stress [int j dev neurosci 16 (1998) 209]. |
2005-10-11 |
2023-08-12 |
mouse |
| H Ishiwata, T Shiga, N Okad. Selective serotonin reuptake inhibitor treatment of early postnatal mice reverses their prenatal stress-induced brain dysfunction. Neuroscience. vol 133. issue 4. 2005-10-11. PMID:15927403. |
since serotonin plays a role in the formation and maintenance of synapses, we hypothesized that a neonatal reduction in hippocampal serotonin levels may lead to learning disabilities in prenatally stressed mice. |
2005-10-11 |
2023-08-12 |
mouse |
| H Ishiwata, T Shiga, N Okad. Selective serotonin reuptake inhibitor treatment of early postnatal mice reverses their prenatal stress-induced brain dysfunction. Neuroscience. vol 133. issue 4. 2005-10-11. PMID:15927403. |
what we found was that the oral administration of a selective serotonin reuptake inhibitor to prenatally stressed mice during postnatal weeks 1-3 but not 6-8 normalized their corticosterone response to stress, serotonin turnover in the hippocampus, and density of dendritic spines and synapses in the hippocampal ca3 region. |
2005-10-11 |
2023-08-12 |
mouse |
| Kelly J Clemens, Jennifer L Cornish, Kong M Li, Glenn E Hunt, Iain S McGrego. MDMA ('Ecstasy') and methamphetamine combined: order of administration influences hyperthermic and long-term adverse effects in female rats. Neuropharmacology. vol 49. issue 2. 2005-10-06. PMID:15993443. |
interestingly, the mdma-->meth treatment produced greater hippocampal and cortical 5-ht depletion than the meth-->mdma treatment suggesting an effect of order. |
2005-10-06 |
2023-08-12 |
rat |
| Bernadett K Szász, Aliz Mayer, Gabriella Zsilla, Balázs Lendvai, E Sylvester Vizi, János P Kis. Carrier-mediated release of monoamines induced by the nicotinic acetylcholine receptor agonist DMPP. Neuropharmacology. vol 49. issue 3. 2005-10-04. PMID:15993437. |
in our experiments dmpp dose-dependently increased the release of dopamine (da) and serotonin (5-ht) from rat striatal and hippocampal slices, respectively. |
2005-10-04 |
2023-08-12 |
rat |
| Bernadett K Szász, Aliz Mayer, Gabriella Zsilla, Balázs Lendvai, E Sylvester Vizi, János P Kis. Carrier-mediated release of monoamines induced by the nicotinic acetylcholine receptor agonist DMPP. Neuropharmacology. vol 49. issue 3. 2005-10-04. PMID:15993437. |
in addition, dmpp dose-dependently inhibited the [3h]da and [3h]5-ht uptake in striatal and hippocampal synaptosome preparation with an ic50 of 3.18 and 0.49 microm, respectively. |
2005-10-04 |
2023-08-12 |
rat |
| Ralph Clinckers, Ilse Smolders, Alfred Meurs, Guy Ebinger, Yvette Michott. Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxcarbazepine: concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity. The Journal of pharmacology and experimental therapeutics. vol 314. issue 2. 2005-09-30. PMID:15860570. |
concomitantly, significant increases in extracellular hippocampal dopamine and serotonin levels were observed within our previously defined anticonvulsant monoamine range. |
2005-09-30 |
2023-08-12 |
rat |
| Sharon Oleskevich, Kwong-Joo Leck, Klaus Matthaei, Ian A Hendr. Enhanced serotonin response in the hippocampus of Galphaz protein knock-out mice. Neuroreport. vol 16. issue 9. 2005-09-30. PMID:15931062. |
enhanced serotonin response in the hippocampus of galphaz protein knock-out mice. |
2005-09-30 |
2023-08-12 |
mouse |
| Jörg-Peter Voigt, Heide Hörtnagl, André Rex, Lil van Hove, Michael Bader, Heidrun Fin. Brain angiotensin and anxiety-related behavior: the transgenic rat TGR(ASrAOGEN)680. Brain research. vol 1046. issue 1-2. 2005-09-27. PMID:15869747. |
in tgr(asraogen)680, tissue content of 5-ht and its metabolite 5-hiaa was lower in the hippocampus, frontal, and parietal cortex. |
2005-09-27 |
2023-08-12 |
rat |
| Lucio Schiapparelli, Joaquín Del Río, Diana Frechill. Serotonin 5-HT receptor blockade enhances Ca(2+)/calmodulin-dependent protein kinase II function and membrane expression of AMPA receptor subunits in the rat hippocampus: implications for memory formation. Journal of neurochemistry. vol 94. issue 4. 2005-09-27. PMID:16092936. |
serotonin 5-ht receptor blockade enhances ca(2+)/calmodulin-dependent protein kinase ii function and membrane expression of ampa receptor subunits in the rat hippocampus: implications for memory formation. |
2005-09-27 |
2023-08-12 |
rat |
| Lucio Schiapparelli, Joaquín Del Río, Diana Frechill. Serotonin 5-HT receptor blockade enhances Ca(2+)/calmodulin-dependent protein kinase II function and membrane expression of AMPA receptor subunits in the rat hippocampus: implications for memory formation. Journal of neurochemistry. vol 94. issue 4. 2005-09-27. PMID:16092936. |
stimulation of hippocampal 5-ht(1a) receptors impairs memory retention. |
2005-09-27 |
2023-08-12 |
rat |