| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feige Tang, Chonghuai Yan, Fei Li, Shenghu Wu, Yongguo Yu, Yu Gao, Xingming Jin, Ying Tian, Xiaoming She. Protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons. Environmental toxicology. vol 22. issue 2. 2007-05-24. PMID:17366564. |
to determine potential neuronal protective effects by insulin, we administered insulin to the cultured hippocampal neurons after exposure to pcbs mixture aroclor 1254 (a 1254). |
2007-05-24 |
2023-08-12 |
Not clear |
| Feige Tang, Chonghuai Yan, Fei Li, Shenghu Wu, Yongguo Yu, Yu Gao, Xingming Jin, Ying Tian, Xiaoming She. Protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons. Environmental toxicology. vol 22. issue 2. 2007-05-24. PMID:17366564. |
we concluded that insulin could protect neurons, probably partly by ameliorating filamentous actin cytoskeleton disruption mediated via the activation of limk-1/cofilin signal pathway in cultured hippocampal neurons after exposure to a 1254. |
2007-05-24 |
2023-08-12 |
Not clear |
| Feige Tang, Chonghuai Yan, Fei Li, Shenghu Wu, Yongguo Yu, Yu Gao, Xingming Jin, Ying Tian, Xiaoming She. Protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons. Environmental toxicology. vol 22. issue 2. 2007-05-24. PMID:17366564. |
the above protective effects in hippocampal neuron may have important implications in the treatment of pcbs-induced neurotoxicity and the mechanism by which insulin improves learning and memory. |
2007-05-24 |
2023-08-12 |
Not clear |
| Dervla O'Malley, Jenni Harve. MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17298596. |
indeed, recent studies have demonstrated that insulin inhibits hippocampal epileptiform-like activity, in part by activating large-conductance ca2+-activated potassium (bk) channels. |
2007-05-02 |
2023-08-12 |
Not clear |
| Dervla O'Malley, Jenni Harve. MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17298596. |
here we demonstrate that in hippocampal neurons, bk channel activation by insulin is blocked by actin filament stabilization, suggesting that this process is dependent on the actin cytoskeleton. |
2007-05-02 |
2023-08-12 |
Not clear |
| Dervla O'Malley, Jenni Harve. MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17298596. |
stabilizing actin filaments also markedly attenuated the ability of insulin to inhibit the aberrant hippocampal synaptic activity evoked following mg2+ removal. |
2007-05-02 |
2023-08-12 |
Not clear |
| Dervla O'Malley, Jenni Harve. MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17298596. |
moreover, in parallel studies, insulin increased the level of phospho-mapk immunostaining in hippocampal neurons. |
2007-05-02 |
2023-08-12 |
Not clear |
| Dervla O'Malley, Jenni Harve. MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17298596. |
this process may have important implications for the role of insulin in regulating hippocampal excitability. |
2007-05-02 |
2023-08-12 |
Not clear |
| M Moosavi, N Naghdi, N Maghsoudi, S Zahedi As. Insulin protects against stress-induced impairments in water maze performance. Behavioural brain research. vol 176. issue 2. 2007-03-02. PMID:17116337. |
the presence of insulin receptor in the hippocampus suggests that this organ is a target for insulin. |
2007-03-02 |
2023-08-12 |
Not clear |
| Boman G Irani, Ambrose A Dunn-Meynell, Barry E Levi. Altered hypothalamic leptin, insulin, and melanocortin binding associated with moderate-fat diet and predisposition to obesity. Endocrinology. vol 148. issue 1. 2007-02-13. PMID:17023527. |
however, he diet intake lowered lateral hypothalamic melanocortin-3 and melanocortin-4 receptor and hippocampal insulin binding of both dio and dr rats and hypothalamic paraventricular nucleus melanocortin-4 receptor binding only in dr rats. |
2007-02-13 |
2023-08-12 |
rat |
| Boman G Irani, Ambrose A Dunn-Meynell, Barry E Levi. Altered hypothalamic leptin, insulin, and melanocortin binding associated with moderate-fat diet and predisposition to obesity. Endocrinology. vol 148. issue 1. 2007-02-13. PMID:17023527. |
these results corroborate our previous findings demonstrating a preexisting decrease in dio hypothalamic leptin and insulin signaling and demonstrate that he diet intake reduces hypothalamic melanocortin and hippocampal insulin binding. |
2007-02-13 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. |
2007-02-09 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
however, how the changes in insulin or glucose levels influence the expression of bprp in hippocampus requires further study. |
2007-02-09 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
here, we investigated the effects of insulin or glucose on the expression of bprp in primary cultured hippocampal neurons. |
2007-02-09 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
we supplied hippocampal neurons with glucose, insulin, or supernatant from pancreatic beta-cells, which secrete insulin into the supernatant. |
2007-02-09 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
our data showed that insulin had beneficial effect on the viability while no significant effect on the expression of bprp in hippocampal neurons. |
2007-02-09 |
2023-08-12 |
rat |
| Yan-Hua Lin, Christel Westenbroek, Lu Tie, Ai-Hua Liu, He-Ming Yu, Gert J Ter Horst, Xue-Jun L. Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus. Neurochemical research. vol 31. issue 12. 2007-02-09. PMID:17091403. |
further study showed that levels of insulin in the supernatant collected from pancreatic beta-cells medium changed over days, and that supernatant increased the viability of hippocampal neurons, while it had no obvious effect on the expression of bprp in hippocampal neurons. |
2007-02-09 |
2023-08-12 |
rat |
| M Moosavi, N Naghdi, N Maghsoudi, S Zahedi As. The effect of intrahippocampal insulin microinjection on spatial learning and memory. Hormones and behavior. vol 50. issue 5. 2007-02-06. PMID:16890939. |
in the present study, the effect of insulin microinjection into ca1 region of rat hippocampus on water maze performance has been investigated. |
2007-02-06 |
2023-08-12 |
rat |
| Buffie J Clodfelder-Miller, Anna A Zmijewska, Gail V W Johnson, Richard S Jop. Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency. Diabetes. vol 55. issue 12. 2007-01-16. PMID:17130475. |
a massive (fivefold average increase) and widespread at multiple residues (detected with eight different phosphorylation-dependent tau antibodies) increase in the phosphorylation of tau was found in mouse cerebral cortex and hippocampus within 3 days of insulin depletion by streptozotocin treatment. |
2007-01-16 |
2023-08-12 |
mouse |
| John G Mielke, Katarina Nicolitch, Vanessa Avellaneda, Karen Earlam, Tarun Ahuja, Geoffrey Mealing, Claude Messie. Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice. Behavioural brain research. vol 175. issue 2. 2007-01-11. PMID:17081630. |
longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in c57bl/6 mice. |
2007-01-11 |
2023-08-12 |
mouse |