| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoichiro Tanaka, Toshihiro Takata, Toyoka Satomi, Takashi Sakurai, Koichi Yokon. The double-edged effect of insulin on the neuronal cell death associated with hypoglycemia on the hippocampal slice culture. The Kobe journal of medical sciences. vol 54. issue 2. 2009-02-13. PMID:18772618. |
to reveal the role of insulin on the neuronal survival, we have used in vitro system of an organotypic hippocampal slice culture from rat, and examine the neuronal cell death at the various glucose concentrations in the presence or absence of insulin. |
2009-02-13 |
2023-08-12 |
rat |
| Alexis M Stranahan, Eric D Norman, Kim Lee, Roy G Cutler, Richard S Telljohann, Josephine M Egan, Mark P Mattso. Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. Hippocampus. vol 18. issue 11. 2009-02-09. PMID:18651634. |
diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. |
2009-02-09 |
2023-08-12 |
rat |
| Hongjuan Wang, Rong Wang, Zhiwei Zhao, Zhijuan Ji, Shiming Xu, Christian Holscher, Shuli Shen. Coexistences of insulin signaling-related proteins and choline acetyltransferase in neurons. Brain research. vol 1249. 2009-01-30. PMID:19013138. |
the aim of the present study is to investigate if insulin signaling-related proteins are co-located with cholinergic neuron in the ca1 region of hippocampus of mice, which could explain the early loss of cholinergic neurons in ad. |
2009-01-30 |
2023-08-12 |
mouse |
| Hongjuan Wang, Rong Wang, Zhiwei Zhao, Zhijuan Ji, Shiming Xu, Christian Holscher, Shuli Shen. Coexistences of insulin signaling-related proteins and choline acetyltransferase in neurons. Brain research. vol 1249. 2009-01-30. PMID:19013138. |
in the ca1 region of hippocampus of mice, several of the insulin signaling-related proteins we had chosen are co-located with chat, and most double immunoreactive positive cells were pyramidal cells. |
2009-01-30 |
2023-08-12 |
mouse |
| N V Gongadze, N A Antelava, T D Kezel. [Imidazoline receptors]. Georgian medical news. issue 160-161. 2008-12-11. PMID:18711237. |
besides to their brainstem location where i1-receptor sites play a significant role to regulate and modulate blood pressure, they also are found in different parts of brain with the highest densities in the striatum, pallidum, hippocampus, amygdala, substantia nigra, while i3-receptor sites were revealed in pancreas which enhances insulin secretion, i2-receptors are widely distributed in interpeduncular nucleus, arcuate and pineal gland and take a part in monoamine turnover. |
2008-12-11 |
2023-08-12 |
Not clear |
| Seong-Woon Yu, Seung-Hoon Baek, Ryan T Brennan, Christopher J Bradley, Se Kyong Park, Yoon Sun Lee, Eun Jung Jun, Keith J Lookingland, Eun-Kyoung Kim, Heuiran Lee, John L Goudreau, Seong Who Ki. Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. Stem cells (Dayton, Ohio). vol 26. issue 10. 2008-11-28. PMID:18653772. |
autophagic death of adult hippocampal neural stem cells following insulin withdrawal. |
2008-11-28 |
2023-08-12 |
rat |
| Seong-Woon Yu, Seung-Hoon Baek, Ryan T Brennan, Christopher J Bradley, Se Kyong Park, Yoon Sun Lee, Eun Jung Jun, Keith J Lookingland, Eun-Kyoung Kim, Heuiran Lee, John L Goudreau, Seong Who Ki. Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. Stem cells (Dayton, Ohio). vol 26. issue 10. 2008-11-28. PMID:18653772. |
hippocampal neural (hcn) stem cells derived from the adult rat brain undergo cell death following insulin withdrawal, which is associated with downregulation of antiapoptotic bcl-2 family members. |
2008-11-28 |
2023-08-12 |
rat |
| Heng Yan Qu, Ting Zhang, Xu Ling Li, Jian Ping Zhou, Bao Quan Zhao, Qian Li, Man Ji Su. Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice. European journal of pharmacology. vol 594. issue 1-3. 2008-11-25. PMID:18644361. |
neprilysin (nep), endothelin-converting enzyme 1 (ece-1) and insulin degrading enzyme (ide), increased in the p11-cntf treated dementia mice, accompanied by the proliferation of nestin- and choline acetyltransferase (chat)-positive cells in hippocampus. |
2008-11-25 |
2023-08-12 |
mouse |
| Li-hong Jiang, Yi-na Zhang, Xiao-wei Wu, Fang-fang Song, Da-yun Gu. Effect of insulin on the cognizing function and expression of hippocampal Abeta1-40 of rat with Alzheimer disease. Chinese medical journal. vol 121. issue 9. 2008-09-09. PMID:18701049. |
effect of insulin on the cognizing function and expression of hippocampal abeta1-40 of rat with alzheimer disease. |
2008-09-09 |
2023-08-12 |
rat |
| Li-hong Jiang, Yi-na Zhang, Xiao-wei Wu, Fang-fang Song, Da-yun Gu. Effect of insulin on the cognizing function and expression of hippocampal Abeta1-40 of rat with Alzheimer disease. Chinese medical journal. vol 121. issue 9. 2008-09-09. PMID:18701049. |
a model of simulated alzheimer's disease (ad) induced by aggregated amyloid protein (abeta(1-40)) was built in wistar rats to observe the behavioral and pathological changes of abeta(1-40) and the effect of hypodermic insulin injected on the function of study and memory and the expression of abeta(1-40) from the ca1 area of the hippocampus. |
2008-09-09 |
2023-08-12 |
rat |
| S Choopani, M Moosavi, N Naghd. Involvement of nitric oxide in insulin induced memory improvement. Peptides. vol 29. issue 6. 2008-08-07. PMID:18295375. |
although brain was considered as an insulin-insensitive organ, recently it has appeared that insulin has some interesting effects on some brain regions like hippocampus. |
2008-08-07 |
2023-08-12 |
rat |
| Alexis M Stranahan, Thiruma V Arumugam, Roy G Cutler, Kim Lee, Josephine M Egan, Mark P Mattso. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18278039. |
rats treated with streptozocin have reduced insulin and show hyperglycemia, increased corticosterone, and impairments in hippocampal neurogenesis, synaptic plasticity and learning. |
2008-06-16 |
2023-08-12 |
mouse |
| Ewan C McNa. Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023257. |
insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. |
2008-01-24 |
2023-08-12 |
Not clear |
| Ewan C McNa. Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023257. |
both insulin and ghrelin are now known to enhance hippocampal memory processes; in addition, insulin acts to increase local hippocampal metabolism and regulate synaptic plasticity, while administration of ghrelin has been shown to promote dendritic spine synaptic formation and to increase anxiety. |
2008-01-24 |
2023-08-12 |
Not clear |
| Ewan C McNa. Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023257. |
while insulin's effects appear to be specifically within the hippocampus, ghrelin may act at a range of sites within the limbic system. |
2008-01-24 |
2023-08-12 |
Not clear |
| Lawrence P Reaga. Insulin signaling effects on memory and mood. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023616. |
the complications of diabetes/obesity phenotypes extend to the central nervous system (cns), including the hippocampus, a brain region that is particularly vulnerable to hyperglycemia and insulin resistance. |
2008-01-24 |
2023-08-12 |
Not clear |
| S Hoyer, H Lanner. Long-term abnormalities in brain glucose/energy metabolism after inhibition of the neuronal insulin receptor: implication of tau-protein. Journal of neural transmission. Supplementum. issue 72. 2007-12-10. PMID:17982895. |
the triplicate intracerebroventricular (icv) application of the diabetogenic compound streptozotocin (stz) in low dosage was used in 1-year-old male wistar rats to induce a damage of the neuronal insulin signal transduction (ist) system and to investigate the activities of hexokinase (hk), phosphofructokinase (pfk), glyceraldehyde-3-phosphate dehydrogenase (gdh), pyruvate kinase (pk), lactate dehydrogenase (ldh) and alpha-ketoglutarate dehydrogenase (alpha-kgdh) in frontoparietotemporal brain cortex (ct) and hippocampus (h) 9 weeks after damage. |
2007-12-10 |
2023-08-12 |
rat |
| M Moosavi, N Naghdi, S Choopan. Intra CA1 insulin microinjection improves memory consolidation and retrieval. Peptides. vol 28. issue 5. 2007-08-24. PMID:17360072. |
in the present study, the effect of insulin microinjection into the ca1 region of rat hippocampus on spatial memory consolidation and retrieval has been investigated. |
2007-08-24 |
2023-08-12 |
rat |
| Shirin Babri, Hamid Gholamipour Badie, Saeed Khamenei, Mehdi Ordikhani Seyedla. Intrahippocampal insulin improves memory in a passive-avoidance task in male wistar rats. Brain and cognition. vol 64. issue 1. 2007-08-07. PMID:17349729. |
the experimental group had posttraining insulin infusion into the ca1 region of dorsal hippocampus, after which they were compared with sham (saline) and control (intact) groups. |
2007-08-07 |
2023-08-12 |
rat |
| Feige Tang, Chonghuai Yan, Fei Li, Shenghu Wu, Yongguo Yu, Yu Gao, Xingming Jin, Ying Tian, Xiaoming She. Protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons. Environmental toxicology. vol 22. issue 2. 2007-05-24. PMID:17366564. |
protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons. |
2007-05-24 |
2023-08-12 |
Not clear |