| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsuyoshi Shimomura, Futoshi Anan, Takayuki Masaki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimatsu, Minoru Fujiki, Hidenori Kobayash. Homocysteine levels are associated with hippocampus volume in type 2 diabetic patients. European journal of clinical investigation. vol 41. issue 7. 2011-09-09. PMID:21250986. |
we tested the hypothesis that elevated thcy levels are correlated with hippocampus volume and insulin resistance in nondementia patients with type 2 diabetes. |
2011-09-09 |
2023-08-12 |
Not clear |
| Sirin Korulu, Arzu Karaba. IGF-1 participates differently in regulation of severing activity of katanin and spastin. Cellular and molecular neurobiology. vol 31. issue 4. 2011-08-16. PMID:21274617. |
to reveal the effects of insulin on regulation of severing activity of p60-katanin and spastin, hippocampal neurons over-expressing spastin and p60-katanin were treated with igf-1. |
2011-08-16 |
2023-08-12 |
human |
| Zhe Jin, Yang Jin, Suresh Kumar-Mendu, Eva Degerman, Leif Groop, Bryndis Birni. Insulin reduces neuronal excitability by turning on GABA(A) channels that generate tonic current. PloS one. vol 6. issue 1. 2011-08-02. PMID:21264261. |
here we show in acute rat hippocampal slices that insulin (1 nm) "turns on" new extrasynaptic gaba(a) channels in ca1 pyramidal neurons resulting in decreased frequency of action potential firing. |
2011-08-02 |
2023-08-12 |
rat |
| Sunmin Park, Da Sol Kim, Sunna Kang, Dae Young Kwo. Ischemic hippocampal cell death induces glucose dysregulation by attenuating glucose-stimulated insulin secretion which is exacerbated by a high fat diet. Life sciences. vol 88. issue 17-18. 2011-06-15. PMID:21362432. |
ischemic hippocampal cell death induces glucose dysregulation by attenuating glucose-stimulated insulin secretion which is exacerbated by a high fat diet. |
2011-06-15 |
2023-08-12 |
Not clear |
| Sunmin Park, Da Sol Kim, Sunna Kang, Dae Young Kwo. Ischemic hippocampal cell death induces glucose dysregulation by attenuating glucose-stimulated insulin secretion which is exacerbated by a high fat diet. Life sciences. vol 88. issue 17-18. 2011-06-15. PMID:21362432. |
we investigated whether ischemic hippocampal neuronal cell death induces glucose dysregulation by modulating insulin resistance, glucose-stimulated insulin secretion, and β-cell mass in mongolian gerbils fed either a high fat or low fat diet. |
2011-06-15 |
2023-08-12 |
Not clear |
| I Valladolid-Acebes, P Stucchi, V Cano, M S Fernández-Alfonso, B Merino, M Gil-Ortega, A Fole, L Morales, M Ruiz-Gayo, N Del Olm. High-fat diets impair spatial learning in the radial-arm maze in mice. Neurobiology of learning and memory. vol 95. issue 1. 2011-05-25. PMID:21093599. |
it has been suggested that hyperglycemia and insulin resistance triggered by energy-dense diets can account for hippocampal damage and deficits of cognitive behaviour. |
2011-05-25 |
2023-08-12 |
mouse |
| Futoshi Anan, Takayuki Masaki, Tsuyoshi Shimomura, Minoru Fujiki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. High-sensitivity C-reactive protein is associated with hippocampus volume in nondementia patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 60. issue 4. 2011-05-23. PMID:20537668. |
we tested the hypothesis that an elevated level of hscrp correlates with hippocampus volume and insulin resistance in nondementia patients with type 2 diabetes mellitus. |
2011-05-23 |
2023-08-12 |
human |
| Futoshi Anan, Takayuki Masaki, Tsuyoshi Shimomura, Minoru Fujiki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. High-sensitivity C-reactive protein is associated with hippocampus volume in nondementia patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 60. issue 4. 2011-05-23. PMID:20537668. |
our results indicate that the elevated level of hscrp in japanese nondementia patients with type 2 diabetes mellitus is characterized by increased hippocampus volume and insulin resistance, and that the z score and homa index are independent predictors of hscrp. |
2011-05-23 |
2023-08-12 |
human |
| Jun Lu, Dong-mei Wu, Zi-hui Zheng, Yuan-lin Zheng, Bin Hu, Zi-feng Zhan. Troxerutin protects against high cholesterol-induced cognitive deficits in mice. Brain : a journal of neurology. vol 134. issue Pt 3. 2011-04-15. PMID:21252113. |
furthermore, troxerutin significantly inhibited the activation of c-jun n-terminal kinase 1 and iκb kinase β/nuclear factor-κb induced by endoplasmic reticulum stress and enhanced insulin signalling pathway, which prevented obesity, restored normal levels of blood glucose, fatty acids and cholesterol and increased the phosphorylation of cyclic adenosine monophosphate response element-binding protein and the expression levels of c-fos in the hippocampus. |
2011-04-15 |
2023-08-12 |
mouse |
| Jun Guo, Caiyong Yu, Hongzeng Li, Fangfang Liu, Rui Feng, Hui Wang, Yanling Meng, Zhuyi Li, Gong Ju, Jian Wan. Impaired neural stem/progenitor cell proliferation in streptozotocin-induced and spontaneous diabetic mice. Neuroscience research. vol 68. issue 4. 2011-03-02. PMID:20832431. |
adx did not alter blood glucose or insulin levels in either prediabetic or diabetic nod mice, but adx partly increased mrna levels of hippocampal and svz brain-derived neurotrophic factor (bdnf), a crucial regulator of nsc/npc proliferation. |
2011-03-02 |
2023-08-12 |
mouse |
| Pretty Mary Abraham, Korah P Kuruvilla, Jobin Mathew, Anitha Malat, Shilpa Joy, C S Paulos. Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose. Journal of biomedical science. vol 17. 2011-02-14. PMID:20868513. |
the present study was carried out to find the effects of insulin, aegle marmelose alone and in combination with pyridoxine on the hippocampal 5-ht, 5-ht(2a) receptor subtype, gene expression studies on 5-ht(2a), 5-htt, insr, immunohistochemical studies and elevated plus maze in streptozotocin induced diabetic rats. |
2011-02-14 |
2023-08-12 |
rat |
| Pretty Mary Abraham, Korah P Kuruvilla, Jobin Mathew, Anitha Malat, Shilpa Joy, C S Paulos. Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose. Journal of biomedical science. vol 17. 2011-02-14. PMID:20868513. |
pyridoxine treated in combination with insulin and a. marmelose to diabetic rats reversed the 5-ht content, b(max), kd of 5-ht, 5-ht(2a) and gene expression of 5-ht(2a), 5-htt and insr in hippocampus to near control. |
2011-02-14 |
2023-08-12 |
rat |
| Pretty Mary Abraham, Korah P Kuruvilla, Jobin Mathew, Anitha Malat, Shilpa Joy, C S Paulos. Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose. Journal of biomedical science. vol 17. 2011-02-14. PMID:20868513. |
our results suggest that pyridoxine treated in combination with insulin and a. marmelose has a role in the regulation of insulin synthesis and release, normalising diabetic related stress and anxiety through hippocampal serotonergic function. |
2011-02-14 |
2023-08-12 |
rat |
| Sandra Wallner-Liebmann, Karl Koschutnig, Gernot Reishofer, Erich Sorantin, Barbara Blaschitz, Renate Kruschitz, Human F Unterrainer, Robert Gasser, Florian Freytag, Carmen Bauer-Denk, Anne Schienle, Axel Schäfer, Harald Mangg. Insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents. Obesity (Silver Spring, Md.). vol 18. issue 8. 2011-02-10. PMID:20168310. |
insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents. |
2011-02-10 |
2023-08-12 |
Not clear |
| Sandra Wallner-Liebmann, Karl Koschutnig, Gernot Reishofer, Erich Sorantin, Barbara Blaschitz, Renate Kruschitz, Human F Unterrainer, Robert Gasser, Florian Freytag, Carmen Bauer-Denk, Anne Schienle, Axel Schäfer, Harald Mangg. Insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents. Obesity (Silver Spring, Md.). vol 18. issue 8. 2011-02-10. PMID:20168310. |
to investigate the relationship between neuronal activation patterns (e.g., hippocampus) to the caloric content of food images and plasma insulin levels, we performed a multiple regression analysis. |
2011-02-10 |
2023-08-12 |
Not clear |
| Sandra Wallner-Liebmann, Karl Koschutnig, Gernot Reishofer, Erich Sorantin, Barbara Blaschitz, Renate Kruschitz, Human F Unterrainer, Robert Gasser, Florian Freytag, Carmen Bauer-Denk, Anne Schienle, Axel Schäfer, Harald Mangg. Insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents. Obesity (Silver Spring, Md.). vol 18. issue 8. 2011-02-10. PMID:20168310. |
interestingly, a significant positive correlation between fasting plasma levels of insulin, waist circumference, and right hippocampal activation was seen after stimulation with high-caloric food images. |
2011-02-10 |
2023-08-12 |
Not clear |
| Sandra Wallner-Liebmann, Karl Koschutnig, Gernot Reishofer, Erich Sorantin, Barbara Blaschitz, Renate Kruschitz, Human F Unterrainer, Robert Gasser, Florian Freytag, Carmen Bauer-Denk, Anne Schienle, Axel Schäfer, Harald Mangg. Insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents. Obesity (Silver Spring, Md.). vol 18. issue 8. 2011-02-10. PMID:20168310. |
the significant positive relationship between hippocampal activation after stimulation with high-caloric food images, plasma insulin levels, and waist circumference suggests a permissive role of insulin signaling pathways in the hippocampal control of eating behavior. |
2011-02-10 |
2023-08-12 |
Not clear |
| Ying Chen, Cui-Ping Cao, Chun-Ri Li, Wei Wang, Dan Zhang, Ling-Ling Han, Xiao-Qing Zhang, Andre Kim, Suhkmann Kim, Guo-Liang Li. Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons. Biological & pharmaceutical bulletin. vol 33. issue 7. 2010-11-26. PMID:20606308. |
ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons. |
2010-11-26 |
2023-08-12 |
Not clear |
| Ying Chen, Cui-Ping Cao, Chun-Ri Li, Wei Wang, Dan Zhang, Ling-Ling Han, Xiao-Qing Zhang, Andre Kim, Suhkmann Kim, Guo-Liang Li. Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons. Biological & pharmaceutical bulletin. vol 33. issue 7. 2010-11-26. PMID:20606308. |
the aim of this study was to investigate whether ghrelin increased high glucose-induced hippocampal neuron insulin sensitivity, and further modulated tau phosphorylation. |
2010-11-26 |
2023-08-12 |
Not clear |
| Ying Chen, Cui-Ping Cao, Chun-Ri Li, Wei Wang, Dan Zhang, Ling-Ling Han, Xiao-Qing Zhang, Andre Kim, Suhkmann Kim, Guo-Liang Li. Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons. Biological & pharmaceutical bulletin. vol 33. issue 7. 2010-11-26. PMID:20606308. |
the effect of ghrelin on hippocampal neuronal insulin sensitivity was detected by [(3)h]-2-deoxy-d-glucose uptake. |
2010-11-26 |
2023-08-12 |
Not clear |