| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Holly M Brothers, Isabelle Bardou, Sarah C Hopp, Roxanne M Kaercher, Angela W Corona, Ashley M Fenn, Jonathan P Godbout, Gary L Wen. Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 8. issue 5. 2014-08-18. PMID:23709339. |
we tested the hypothesis that if impaired spatial memory results from increased extracellular glutamate due to age or experimentally induced chronic neuroinflammation in the hippocampus, then pharmacological augmentation of the glutamate transporter glt1 will attenuate deficits in a hippocampal-dependent spatial memory task. |
2014-08-18 |
2023-08-12 |
rat |
| Jacqueline R Kulbe, Jean M Mulcahy Levy, Steven J Coultrap, Andrew Thorburn, K Ulrich Baye. Excitotoxic glutamate insults block autophagic flux in hippocampal neurons. Brain research. vol 1542. 2014-08-15. PMID:24505621. |
excitotoxic glutamate insults block autophagic flux in hippocampal neurons. |
2014-08-15 |
2023-08-12 |
Not clear |
| Jacqueline R Kulbe, Jean M Mulcahy Levy, Steven J Coultrap, Andrew Thorburn, K Ulrich Baye. Excitotoxic glutamate insults block autophagic flux in hippocampal neurons. Brain research. vol 1542. 2014-08-15. PMID:24505621. |
while tatcn21 partially inhibited basal autophagy in hippocampal neurons, it had no effects on the already blocked autophagy after excitotoxic glutamate insults, indicating that autophagy inhibition is not its neuroprotective mechanism. |
2014-08-15 |
2023-08-12 |
Not clear |
| Hui Lu, Hyungju Park, Mu-Ming Po. Spike-timing-dependent BDNF secretion and synaptic plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298135. |
by monitoring changes in the green fluorescent protein (gfp) fluorescence at the dendrite of hippocampal neurons expressing gfp-tagged bdnf, we found that pairing of iontophoretic glutamate pulses with neuronal spiking resulted in bdnf secretion from the dendrite at the iontophoretic site only when the glutamate pulses were applied within a time window of approximately 40 ms prior to neuronal spiking, consistent with the timing requirement of synaptic potentiation via stdp. |
2014-08-11 |
2023-08-12 |
Not clear |
| Elizabeth Nicholson, Dimitri M Kullman. Long-term potentiation in hippocampal oriens interneurons: postsynaptic induction, presynaptic expression and evaluation of candidate retrograde factors. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298136. |
several types of hippocampal interneurons exhibit a form of long-term potentiation (ltp) that depends on ca(2+)-permeable ampa receptors and group i metabotropic glutamate receptors. |
2014-08-11 |
2023-08-12 |
mouse |
| Tiina Maria Pirttimaki, Neela Krushna Codadu, Alia Awni, Pandey Pratik, David Andrew Nagel, Eric James Hill, Kelly Tennyson Dineley, H Rheinallt Parr. α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312364. |
since α7nachrs are highly permeable to calcium and are expressed on hippocampal astrocytes, we investigated whether aβ could activate astrocytic α7nachrs in hippocampal slices and induce gt glutamate release. |
2014-08-05 |
2023-08-12 |
mouse |
| Tiina Maria Pirttimaki, Neela Krushna Codadu, Alia Awni, Pandey Pratik, David Andrew Nagel, Eric James Hill, Kelly Tennyson Dineley, H Rheinallt Parr. α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312364. |
these findings suggest that, at an age that far precedes the emergence of cognitive deficits and plaque deposition, this mouse model for ad-like amyloidosis exhibits augmented astrocytic activity and glutamate gt release suggesting possible repercussions for preclinical ad hippocampal neural networks that contribute to subsequent cognitive decline. |
2014-08-05 |
2023-08-12 |
mouse |
| Keisuke Shinohara, Toshimichi Hat. Post-acquisition hippocampal NMDA receptor blockade sustains retention of spatial reference memory in Morris water maze. Behavioural brain research. vol 259. 2014-08-04. PMID:24257072. |
several studies have demonstrated that the hippocampal n-methyl-d-aspartate type glutamate receptors (nmdars) are necessary for the acquisition but not the retention of spatial reference memory. |
2014-08-04 |
2023-08-12 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
in the present study, we investigated how the level of extracellular (tonic) gaba affects release of [(3)h]ne in hippocampal slices of male and female shr, wky and sd rats, in response to 3 glutamate stimulations (s1, s2, and s3). |
2014-07-28 |
2023-08-12 |
rat |
| Ashok Jangra, Ashok Kumar Datusalia, Shriya Khandwe, Shyam Sunder Sharm. Amelioration of diabetes-induced neurobehavioral and neurochemical changes by melatonin and nicotinamide: implication of oxidative stress-PARP pathway. Pharmacology, biochemistry, and behavior. vol 114-115. 2014-07-22. PMID:24201044. |
glutamate and gaba levels were also altered in hippocampus of the diabetic animals. |
2014-07-22 |
2023-08-12 |
rat |
| Audrée De Montigny, Ismaël Elhiri, Julie Allyson, Michel Cyr, Guy Massicott. NMDA reduces Tau phosphorylation in rat hippocampal slices by targeting NR2A receptors, GSK3β, and PKC activities. Neural plasticity. vol 2013. 2014-07-22. PMID:24349798. |
in the present study, pharmacological inhibitors were deployed to investigate potential processes by which the n-methyl-d-aspartate (nmda) subtype of glutamate receptors modulates tau phosphorylation in rat hippocampal slices. |
2014-07-22 |
2023-08-12 |
rat |
| Pengbo Yang, Junfeng Zhang, Lingyu Zhao, Qian Jiao, Hui Jin, Xinli Xiao, Haixia Zhang, Ming Hu, Haixia Lu, Yong Li. Developmental distribution pattern of metabotropic glutamate receptor 5 in prenatal human hippocampus. Neuroscience bulletin. vol 28. issue 6. 2014-07-21. PMID:23225313. |
developmental distribution pattern of metabotropic glutamate receptor 5 in prenatal human hippocampus. |
2014-07-21 |
2023-08-12 |
human |
| Tae Kyung Kim, Jai-Yoon Sul, Henrik Helmfors, Ulo Langel, Junhyong Kim, James Eberwin. Dendritic glutamate receptor mRNAs show contingent local hotspot-dependent translational dynamics. Cell reports. vol 5. issue 1. 2014-07-21. PMID:24075992. |
cotransfection of glutamate receptor 2 (glur2) and glur4 mrnas (engineered to encode different fluorescent proteins) into rat hippocampal neurons demonstrates a heterogeneous distribution of translational hotspots for the two mrnas along dendrites. |
2014-07-21 |
2023-08-12 |
rat |
| V Iu Maslov, M S Veselovs'kyĭ, A O Moskaliuk, M F M"iasoiedov, S I Shram, S A Fedulov. [Pretective action of peptide pro-gly-pro on electrophysiological characteristics of cultured hippocampal neurones during excitotoxic damage]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 60. issue 2. 2014-07-17. PMID:25007514. |
electrophysiological characteristics of hippocampal neurones cultured with pro-gly-pro peptide were studied using glutamate excitotoxisity model (excitotoxic damage was induced by 100 mkm glutamate application during 5 min). |
2014-07-17 |
2023-08-13 |
Not clear |
| Hyungju Park, Kyung-Seok Han, Soo-Jin Oh, Seonmi Jo, Junsung Woo, Bo-Eun Yoon, C Justin Le. High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte. Molecular brain. vol 6. 2014-07-15. PMID:24321245. |
high glutamate permeability and distal localization of best1 channel in ca1 hippocampal astrocyte. |
2014-07-15 |
2023-08-12 |
mouse |
| Francesco Ventrigli. Random dispersion in excitatory synapse response. Cognitive neurodynamics. vol 8. issue 4. 2014-07-10. PMID:25009674. |
a model of an excitatory (hippocampal) synapse, based on time discretized langevin equations (time-step = 40 fs), was introduced to describe the brownian motion of glutamate molecules (gluts) within the synaptic cleft and their binding to postsynaptic receptors. |
2014-07-10 |
2023-08-13 |
human |
| Ludmyla Kandratavicius, Pedro Rosa-Neto, Mariana Raquel Monteiro, Marie-Christine Guiot, Joao Alberto Assirati, Carlos Gilberto Carlotti, Eliane Kobayashi, Joao Pereira Leit. Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23804486. |
distinct increased metabotropic glutamate receptor type 5 (mglur5) in temporal lobe epilepsy with and without hippocampal sclerosis. |
2014-07-09 |
2023-08-12 |
Not clear |
| Ludmyla Kandratavicius, Pedro Rosa-Neto, Mariana Raquel Monteiro, Marie-Christine Guiot, Joao Alberto Assirati, Carlos Gilberto Carlotti, Eliane Kobayashi, Joao Pereira Leit. Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23804486. |
metabotropic glutamate receptor type 5 (mglur5) upregulation in temporal lobe epilepsy (tle) and the correlation of its expression with features of hippocampal sclerosis (hs) remains unclear. |
2014-07-09 |
2023-08-12 |
Not clear |
| Chang-Jun Li, Mei Zhou, Hui-Ge Li, Qing Lv, Xu-Lin Xu, Lian-Jun Gu. Clonidine suppresses the induction of long-term potentiation by inhibiting HCN channels at the Schaffer collateral-CA1 synapse in anesthetized adult rats. Cellular and molecular neurobiology. vol 33. issue 8. 2014-07-08. PMID:23975095. |
furthermore, clonidine at 1 and 10 μm significantly decreased glutamate (glu) content in the culture supernatants of hippocampal neurons, and yohimbine at 1 and 10 μm had no effect on glu release, while it could reverse the inhibition of clonidine (1 and 10 μm) on glu release. |
2014-07-08 |
2023-08-12 |
rat |
| Andrew P Mayer, Ivan Osorio, Craig E Lunt. Microperfusion of 3-MPA into the brain augments GABA. Epilepsy & behavior : E&B. vol 29. issue 3. 2014-07-03. PMID:24094842. |
paradoxical elevations in gaba in the striatum (5-fold in anesthetized and 50-fold in awake rats) and hippocampus (2-fold in anesthetized and 15-fold in awake rats) were documented under steady-state concentrations of 3-mpa along with expected increases in glutamate (a 15-fold increase and a 250-fold increase in the striatum of anesthetized and awake rats, respectively; a 7-fold increase and a 25-fold increase in the hippocampus of anesthetized and awake rats, respectively). |
2014-07-03 |
2023-08-12 |
rat |