| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David N Guilfoyle, Scott Gerum, Csaba Vadas. In vivo Proton NMR spectroscopy of genetic mouse models BALB/cJ and C57BL/6By: variation in hippocampal glutamate level and the metabotropic glutamate receptor, subtype 7 (Grm7) gene. Journal of molecular neuroscience : MN. vol 53. issue 1. 2014-12-14. PMID:24390354. |
in vivo proton nmr spectroscopy of genetic mouse models balb/cj and c57bl/6by: variation in hippocampal glutamate level and the metabotropic glutamate receptor, subtype 7 (grm7) gene. |
2014-12-14 |
2023-08-12 |
mouse |
| David N Guilfoyle, Scott Gerum, Csaba Vadas. In vivo Proton NMR spectroscopy of genetic mouse models BALB/cJ and C57BL/6By: variation in hippocampal glutamate level and the metabotropic glutamate receptor, subtype 7 (Grm7) gene. Journal of molecular neuroscience : MN. vol 53. issue 1. 2014-12-14. PMID:24390354. |
the results showed that the hippocampal level of glutamate in the congenic mouse strain was significantly lower than that in the background c57bl/6by strain which carried the grm7 (c57bl/6by) allele. |
2014-12-14 |
2023-08-12 |
mouse |
| David N Guilfoyle, Scott Gerum, Csaba Vadas. In vivo Proton NMR spectroscopy of genetic mouse models BALB/cJ and C57BL/6By: variation in hippocampal glutamate level and the metabotropic glutamate receptor, subtype 7 (Grm7) gene. Journal of molecular neuroscience : MN. vol 53. issue 1. 2014-12-14. PMID:24390354. |
because the two inbred strains are genetically highly similar except at the region of the grm7 gene, the results raise the possibility that allelic variation at the grm7 locus contributes to the strain differences in both hippocampal mrna abundance and glutamate level which may modulate complex behavioral traits, such as learning and memory, addiction, epilepsy, and mood disorders. |
2014-12-14 |
2023-08-12 |
mouse |
| J Egea, A Romero, E Parada, R León, T Dal-Cim, M G Lópe. Neuroprotective effect of dimebon against ischemic neuronal damage. Neuroscience. vol 267. 2014-12-09. PMID:24607349. |
this study was conducted to evaluate the potential neuroprotective effect of dimebon during brain ischemia using rat hippocampal slices subjected to oxygen and glucose deprivation followed by a reoxygenation period (ogd/reox) or glutamate excitotoxicity. |
2014-12-09 |
2023-08-12 |
rat |
| C S Harrell, J Burgado, S D Kelly, G N Neig. Ovarian steroids influence cerebral glucose transporter expression in a region- and isoform-specific pattern. Journal of neuroendocrinology. vol 26. issue 4. 2014-12-09. PMID:24612045. |
the present study demonstrates the extent to which hormonal variation across the four stages of the rat oestrous cycle affects the mrna abundance of four members of the glut family, including the most well characterised cerebral transporters slc2a1 and slc2a3, as well as the insulin-sensitive transporters slc2a4 and slc2a8 in the hypothalamus, hippocampus and prefrontal cortex. |
2014-12-09 |
2023-08-12 |
rat |
| C S Harrell, J Burgado, S D Kelly, G N Neig. Ovarian steroids influence cerebral glucose transporter expression in a region- and isoform-specific pattern. Journal of neuroendocrinology. vol 26. issue 4. 2014-12-09. PMID:24612045. |
furthermore, ovarian hormones are critical for normal expression of glut mrna, as demonstrated by reduced expression of slc2a1, slc2a3 and sl2a8 in the hippocampus after ovariectomy. |
2014-12-09 |
2023-08-12 |
rat |
| Timothy A Couttas, Nupur Kain, Benjamin Daniels, Xin Ying Lim, Claire Shepherd, Jillian Kril, Russell Pickford, Hongyun Li, Brett Garner, Anthony S Do. Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis. Acta neuropathologica communications. vol 2. 2014-12-08. PMID:24456642. |
s1p is derived by phosphorylation of sphingosine, catalysed by sphingosine kinases 1 and 2 (sphk1 and 2), and sphk1 positively regulates glutamate secretion and synaptic strength in hippocampal neurons. |
2014-12-08 |
2023-08-12 |
human |
| Catarina Rendeiro, Andrew Foley, Vera C Lau, Rebecca Ring, Ana Rodriguez-Mateos, David Vauzour, Claire M Williams, Ciaran Regan, Jeremy P E Spence. A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats. Neuropharmacology. vol 79. 2014-12-03. PMID:24333331. |
we observed parallel increases in hippocampal nmda receptors containing the nr2b subunit for both 8.7 mg/day (p < 0.05) and 17.4 mg/day (p < 0.001) doses, suggesting an enhancement of glutamate signaling following flavonoid intervention. |
2014-12-03 |
2023-08-12 |
rat |
| Nino Tabatadze, Rhona McGonigal, Rachel L Neve, Aryeh Routtenber. Activity-dependent Wnt 7 dendritic targeting in hippocampal neurons: plasticity- and tagging-related retrograde signaling mechanism? Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24375790. |
as a first step in such an analysis, we show here that wnt 7 levels in primary hippocampal cells are elevated by potassium or glutamate activation in a time-dependent manner. |
2014-12-03 |
2023-08-12 |
rat |
| Sha Sha, Libin Zhou, Jun Yin, Koga Takamiya, Keiko Furukawa, Koichi Furukawa, Masahiro Sokabe, Ling Che. Deficits in cognitive function and hippocampal plasticity in GM2/GD2 synthase knockout mice. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24765676. |
schaffer collateral-ca1 synapses in the hippocampal slices from gm2/gd2−/− mice showed an increase in the slope of epsps with reduced paired-pulse facilitation, indicating an enhancement of their presynaptic glutamate release. |
2014-12-03 |
2023-08-13 |
mouse |
| Mimi A Trinh, Tao Ma, Hanoch Kaphzan, Aditi Bhattacharya, Marcia D Antion, Douglas R Cavener, Charles A Hoeffer, Eric Klan. The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 5. 2014-12-01. PMID:24741110. |
the eif2α kinase perk limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. |
2014-12-01 |
2023-08-13 |
mouse |
| Mimi A Trinh, Tao Ma, Hanoch Kaphzan, Aditi Bhattacharya, Marcia D Antion, Douglas R Cavener, Charles A Hoeffer, Eric Klan. The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 5. 2014-12-01. PMID:24741110. |
here, we demonstrate that in hippocampal area ca1, metabotropic glutamate receptor (mglur)-dependent long-term depression (ltd) is associated with increased eif2α phosphorylation, whereas stimulation of early- and late-phase long-term potentiation (e-ltp and l-ltp, respectively) is associated with decreased eif2α phosphorylation. |
2014-12-01 |
2023-08-13 |
mouse |
| Sara Poletti, Clara Locatelli, Daniele Radaelli, Cristina Lorenzi, Enrico Smeraldi, Cristina Colombo, Francesco Benedett. Effect of early stress on hippocampal gray matter is influenced by a functional polymorphism in EAAT2 in bipolar disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24518437. |
the aim of the study is to investigate the effect of glutamate transporter polymorphism slc1a2-181a>c and exposure to adverse childhood experiences (ace) on hippocampal gray matter volume of patients with bipolar disorder (bd). |
2014-11-25 |
2023-08-12 |
Not clear |
| Flávio Afonso Gonçalves Mourão, Hércules Ribeiro Leite, Luciana Estefani Drumond de Carvalho, Talita Hélen Ferreira E Vieira, Mauro Cunha Xavier Pinto, Daniel de Castro Medeiros, Ian Lara Lamounier Andrade, Daniela Fontes Gonçalves, Grace Schenatto Pereira, Márcio Flávio Dutra Moraes, André Ricardo Massensin. Neuroprotective effect of exercise in rat hippocampal slices submitted to in vitro ischemia is promoted by decrease of glutamate release and pro-apoptotic markers. Journal of neurochemistry. vol 131. issue 1. 2014-11-21. PMID:24903976. |
neuroprotective effect of exercise in rat hippocampal slices submitted to in vitro ischemia is promoted by decrease of glutamate release and pro-apoptotic markers. |
2014-11-21 |
2023-08-13 |
rat |
| Pelin Cengiz, Douglas B Kintner, Vishal Chanana, Hui Yuan, Erinc Akture, Pinar Kendigelen, Gulnaz Begum, Emin Fidan, Kutluay Uluc, Peter Ferrazzano, Dandan Su. Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation. PloS one. vol 9. issue 1. 2014-11-18. PMID:24392123. |
hippocampal astrocytes also exhibited a robust release of gliotransmitters (glutamate and pro-inflammatory cytokines il-6 and tnfα) during 1-24 h reox. |
2014-11-18 |
2023-08-12 |
mouse |
| Jie Gao, He Wang, Yuan Liu, Ying-Yu Li, Can Chen, Liang-Ming Liu, Ya-Min Wu, Sen Li, Ce Yan. Glutamate and GABA imbalance promotes neuronal apoptosis in hippocampus after stress. Medical science monitor : international medical journal of experimental and clinical research. vol 20. 2014-11-18. PMID:24675061. |
glutamate and gaba imbalance promotes neuronal apoptosis in hippocampus after stress. |
2014-11-18 |
2023-08-12 |
Not clear |
| Sunggu Yang, Sungchil Yang, Thais Moreira, Gloria Hoffman, Greg C Carlson, Kevin J Bender, Bradley E Alger, Cha-Min Tan. Interlamellar CA1 network in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 35. 2014-11-12. PMID:25139992. |
here, using a battery of powerful techniques, including 3d digital holography and focal glutamate uncaging, voltage-sensitive dye, two-photon imaging, electrophysiology, and immunohistochemistry, we show that ca1 pyramidal neurons are connected to one another in an associational and well-organized fashion along the longitudinal axis of the hippocampus. |
2014-11-12 |
2023-08-13 |
Not clear |
| Teruko M Bredemann, Lori L McMaho. 17β Estradiol increases resilience and improves hippocampal synaptic function in helpless ovariectomized rats. Psychoneuroendocrinology. vol 42. 2014-11-07. PMID:24636504. |
stress decreases hippocampal dendritic spine density and long-term potentiation (ltp) at glutamate synapses, a cellular correlate of learning and memory. |
2014-11-07 |
2023-08-12 |
rat |
| In-Young Choi, Phil Lee, Wen-Tung Wang, Dongwei Hui, Xinkun Wang, William M Brooks, Elias K Michaeli. Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice. Neurochemical research. vol 39. issue 3. 2014-11-06. PMID:24442550. |
metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice. |
2014-11-06 |
2023-08-12 |
mouse |
| John L Robinson, Laura Molina-Porcel, Maria M Corrada, Kevin Raible, Edward B Lee, Virginia M-Y Lee, Claudia H Kawas, John Q Trojanowsk. Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old. Brain : a journal of neurology. vol 137. issue Pt 9. 2014-11-06. PMID:25012223. |
relative immunohistochemistry intensity measures were obtained for synaptophysin, synaptic vesicle transporter sv2 (now known as sv2a) and vesicular glutamate transporter 1 in the outer molecular layer of the hippocampal dentate gyrus on the first 157 participants of 'the 90+ study' who came to autopsy, including participants with dementia (n = 84), those with cognitive impairment but no dementia (n = 37) and those with normal cognition (n = 36). |
2014-11-06 |
2023-08-13 |
human |