| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fawaz Alasmari, Laura E Crotty Alexander, Alaa M Hammad, Austin Horton, Hasan Alhaddad, Isaac T Schiefer, John Shin, Alexander Moshensky, Youssef Sar. E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. Chemico-biological interactions. vol 333. 2020-12-29. PMID:33242460. |
we investigated the effects of daily e-cigarette exposure on protein levels of α7 nachr and α4/β2 nachr, gene expression and protein levels of astroglial glutamate transporters, including glutamate transporter-1 (glt-1) and cystine/glutamate antiporter (xct), in the frontal cortex (fc), striatum (str) and hippocampus (hip). |
2020-12-29 |
2023-08-13 |
mouse |
| Lace M Riggs, Yasco Aracava, Panos Zanos, Jonathan Fischell, Edson X Albuquerque, Edna F R Pereira, Scott M Thompson, Todd D Goul. (2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 2. 2020-12-28. PMID:31216563. |
overall, we found that (2r,6r)-hnk enhances excitatory synaptic transmission in the hippocampus through a concentration-dependent, nmdar-independent, and synapse-selective increase in glutamate release probability with no direct actions on ampar function. |
2020-12-28 |
2023-08-13 |
rat |
| Oliver D Howes, Ilaria Bonoldi, Robert A McCutcheon, Matilda Azis, Mathilde Antoniades, Matthijs Bossong, Gemma Modinos, Jesus Perez, James M Stone, Barbara Santangelo, Mattia Veronese, Anthony Grace, Paul Allen, Philip K McGuir. Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31618752. |
the aim of this study was to examine the relationship between hippocampal glutamate and subcortical dopaminergic function in people at clinical high risk for psychosis, and to assess the association with the development of psychotic symptoms. |
2020-12-28 |
2023-08-13 |
Not clear |
| Hasan Alhaddad, Woonyen Wong, Adam T Sari, Laura E Crotty Alexander, Youssef Sar. Effects of 3-Month Exposure to E-Cigarette Aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice. Toxics. vol 8. issue 4. 2020-12-26. PMID:33137879. |
in this study, we evaluated the effect of three months' continuous exposure to e-cig vapor (juul pods), containing a high nicotine concentration, on the expression of glutamate receptors and transporters in drug reward brain regions such as the nucleus accumbens (nac) core (nac-core), nac shell (nac-shell) and hippocampus (hip) in female c57bl/6 mice. |
2020-12-26 |
2023-08-13 |
mouse |
| Yu-Xiang Wang, Zhen-Hong Xia, Xue Jiang, Li-Xia Li, Hong-Gang Wang, Di An, Yan-Qiang Li. Genistein inhibits amyloid peptide 25-35-induced neuronal death by modulating estrogen receptors, choline acetyltransferase and glutamate receptors. Archives of biochemistry and biophysics. vol 693. 2020-12-21. PMID:32857999. |
to explore genistein, the most active component of soy isoflavones, on viability, expression of estrogen receptor (er) subtypes, choline acetyltransferase (chat), and glutamate receptor subunits in amyloid peptide 25-35-induced hippocampal neurons, providing valuable data and basic information for neuroprotective effect of genistein in aβ |
2020-12-21 |
2023-08-13 |
Not clear |
| Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
together, these results suggest that fwp contains effective constituents and alleviates depression with ldsds by regulating ampa-type glutamate receptor homeostasis in amygdala and hippocampus. |
2020-12-19 |
2023-08-13 |
rat |
| Oleg O Glebo. Tonic NMDA receptor signalling shapes endosomal organisation in mammalian cells. Scientific reports. vol 10. issue 1. 2020-12-16. PMID:32518335. |
this effect can be mimicked by blockade of nmda-type glutamate receptors but not voltage-gated calcium channels (vgccs), and can also be observed in primary hippocampal neurons and jurkat t cells. |
2020-12-16 |
2023-08-13 |
human |
| Emilio Garro-Martínez, Rebeca Vidal, Albert Adell, Álvaro Díaz, Elena Castro, Josep Amigó, Raquel Gutiérrez-Lanza, Eva Florensa-Zanuy, Laura Gómez-Acero, M Mark Taketo, Ángel Pazos, Fuencisla Pilar-Cuélla. β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System. Molecular neurobiology. vol 57. issue 3. 2020-12-04. PMID:31823197. |
we previously reported that the inactivation (cko) or the stabilization (cst) of β-catenin in cells expressing the astrocyte-specific glutamate aspartate transporter (glast) is associated with the vulnerability or resilience to exhibit anxious/depressive-like behaviors, respectively, and to changes in hippocampal proliferation. |
2020-12-04 |
2023-08-13 |
mouse |
| Raquel García-García, Juan F Guerrero, Manuel Lavilla-Miyasato, Jose R Magdalena, Juan F Ordoño, Marta Llansola, Carmina Montoliu, Vicent Teruel-Martí, Vicente Felip. Hyperammonemia alters the mismatch negativity in the auditory evoked potential by altering functional connectivity and neurotransmission. Journal of neurochemistry. vol 154. issue 1. 2020-12-04. PMID:31840253. |
hyperammonemia also alters membrane expression of glutamate and gaba receptors in hippocampus and reduces the changes in extracellular gaba and glutamate induced by the mmn paradigm of auditory stimulus in hippocampus of control rats. |
2020-12-04 |
2023-08-13 |
rat |
| Alicja Skórkowska, Alicja Maciejska, Bartosz Pomierny, Weronika Krzyżanowska, Beata Starek-Świechowicz, Beata Bystrowska, Żaneta Broniowska, Grzegorz Kazek, Bogusława Budziszewsk. Effect of Combined Prenatal and Adult Benzophenone-3 Dermal Exposure on Factors Regulating Neurodegenerative Processes, Blood Hormone Levels, and Hematological Parameters in Female Rats. Neurotoxicity research. vol 37. issue 3. 2020-12-04. PMID:31970650. |
although bp-3 did not induce apoptosis in the hippocampus and frontal cortex, the increased extracellular glutamate concentration and lipid peroxidation, as well as impaired spatial memory, suggested that this compound also had adverse effects in the female brain yet was weaker than in males. |
2020-12-04 |
2023-08-13 |
rat |
| Brittany E Dong, Hao Chen, Kazuko Sakat. BDNF deficiency and enriched environment treatment affect neurotransmitter gene expression differently across ages. Journal of neurochemistry. vol 154. issue 1. 2020-12-04. PMID:32222968. |
high-throughput quantitative reverse transcription polymerase chain reaction measured expression of 81 genes for dopamine, adrenaline, serotonin, gamma aminobutyric acid, glutamate, acetylcholine, and bdnf systems in the frontal cortex (fc) and hippocampus. |
2020-12-04 |
2023-08-13 |
mouse |
| Der-Yen Lee, Yu-Rung Jiu, Ching-Liang Hsie. Electroacupuncture at Zusanli and at Neiguan characterized point specificity in the brain by metabolomic analysis. Scientific reports. vol 10. issue 1. 2020-12-04. PMID:32612281. |
ea at pc6 resulted in downregulation of adenosine, adrenaline, γ-aminobutyric acid, glycine, and glutamate majorly in hippocampus, and then in cerebral cortex. |
2020-12-04 |
2023-08-13 |
rat |
| Akira Minami, Yuka Fujita, Sumika Shimba, Mako Shiratori, Yukiko K Kaneko, Toshiaki Sawatani, Tadamune Otsubo, Kiyoshi Ikeda, Hiroaki Kanazawa, Yasuyo Mikami, Risa Sekita, Yuuki Kurebayashi, Tadanobu Takahashi, Taeko Miyagi, Tomohisa Ishikawa, Takashi Suzuk. The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:32251344. |
the sialidase inhibitor 2,3-dehydro-2-deoxy-n-acetylneuraminic acid (dana) remarkably enhances glutamate release from hippocampal neurons. |
2020-11-30 |
2023-08-13 |
mouse |
| Benjamin Spurny, Rene Seiger, Philipp Moser, Thomas Vanicek, Murray B Reed, Eva Heckova, Paul Michenthaler, Alim Basaran, Gregor Gryglewski, Manfred Klöbl, Siegfried Trattnig, Siegfried Kasper, Wolfgang Bogner, Rupert Lanzenberge. Hippocampal GABA levels correlate with retrieval performance in an associative learning paradigm. NeuroImage. vol 204. 2020-11-27. PMID:31606475. |
changes of gaba and glutamate were compared to retrieval success in the hippocampus, insula and thalamus. |
2020-11-27 |
2023-08-13 |
human |
| Siju Ellickal Narayanan, Nisha Abdul Rehuman, Seetha Harilal, Anju Vincent, Rajalakshmi Ganesan Rajamma, Tapan Behl, Md Sahab Uddin, Ghulam Md Ashraf, Bijo Mathe. Molecular mechanism of zinc neurotoxicity in Alzheimer's disease. Environmental science and pollution research international. vol 27. issue 35. 2020-11-25. PMID:32909132. |
zn also regulates excitatory and inhibitory neurotransmitters such as glutamate and gaba and is found in high concentration in the synaptic terminals of hippocampal mossy fibers that maintains cognitive function. |
2020-11-25 |
2023-08-13 |
human |
| Mostofa Jamal, Asuka Ito, Naoko Tanaka, Takanori Miki, Kiyoshi Ameno, Hiroshi Kinoshit. High Ethanol and Acetaldehyde Inhibit Glutamatergic Transmission in the Hippocampus of Aldh2-Knockout and C57BL/6N Mice: an In Vivo and Ex Vivo Analysis. Neurotoxicity research. vol 37. issue 3. 2020-11-20. PMID:32062779. |
we aimed to investigate whether ethanol (etoh) and acetaldehyde (ach) can affect glutamate and its receptors glun1 and glua1 in the hippocampus of aldh2-knockout (aldh2-ko) and c57bl/6n (wild-type (wt)) mice. |
2020-11-20 |
2023-08-13 |
mouse |
| Mostofa Jamal, Asuka Ito, Naoko Tanaka, Takanori Miki, Kiyoshi Ameno, Hiroshi Kinoshit. High Ethanol and Acetaldehyde Inhibit Glutamatergic Transmission in the Hippocampus of Aldh2-Knockout and C57BL/6N Mice: an In Vivo and Ex Vivo Analysis. Neurotoxicity research. vol 37. issue 3. 2020-11-20. PMID:32062779. |
retrodialysis of 200 mm and 500 mm etoh into the hippocampus of wt and aldh2-ko mice produced significant decreases in extracellular glutamate levels (p < 0.05). |
2020-11-20 |
2023-08-13 |
mouse |
| Mostofa Jamal, Asuka Ito, Naoko Tanaka, Takanori Miki, Kiyoshi Ameno, Hiroshi Kinoshit. High Ethanol and Acetaldehyde Inhibit Glutamatergic Transmission in the Hippocampus of Aldh2-Knockout and C57BL/6N Mice: an In Vivo and Ex Vivo Analysis. Neurotoxicity research. vol 37. issue 3. 2020-11-20. PMID:32062779. |
together, these in vivo and ex vivo data suggest that etoh and ach decrease extracellular glutamate in the hippocampus of mice with a concomitant decrease in glun1 and glua1 subunits, but these effects require relatively high concentrations and may, therefore, explain the consequences of etoh intoxication. |
2020-11-20 |
2023-08-13 |
mouse |
| Amita Shrestha, Philip A Adeniyi, Olalekan M Ogundel. Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus. Journal of visualized experiments : JoVE. issue 163. 2020-11-20. PMID:32986031. |
combined in vivo anatomical and functional tracing of ventral tegmental area glutamate terminals in the hippocampus. |
2020-11-20 |
2023-08-13 |
mouse |
| Amita Shrestha, Philip A Adeniyi, Olalekan M Ogundel. Combined In Vivo Anatomical and Functional Tracing of Ventral Tegmental Area Glutamate Terminals in the Hippocampus. Journal of visualized experiments : JoVE. issue 163. 2020-11-20. PMID:32986031. |
the current study demonstrates how vta glutamate neurons modulate the firing rate of putative pyramidal neurons in the ca1 (hippocampus) of anesthetized mice. |
2020-11-20 |
2023-08-13 |
mouse |