| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui-Fei Jie, Guang-Ju Yang, Rui-Yun Bi, Si-Yi Mo, Ye-Hua Gan, Qiu-Fei Xi. Genistein Antagonizes 17β-Estradiol Effects on Glutamate-Evoked Masseter Muscle Hypernociception in Rats. Frontiers in neurology. vol 9. 2020-10-01. PMID:30166977. |
on the molecular level, tyrosine phosphorylation of the nr2b subunit of the n-methyl-d-aspartate receptor (pnr2b) and phosphorylated mitogen-activated protein kinase (perk1/2) were significantly upregulated in the hippocampus following glutamate injection and were further potentiated by e2 replacement. |
2020-10-01 |
2023-08-13 |
rat |
| Li Jin, Yi-Pei Li, Qiong Feng, Li Ren, Fang Wang, Guo-Jia Bo, Li Wan. Cognitive deficits and Alzheimer-like neuropathological impairments during adolescence in a rat model of type 2 diabetes mellitus. Neural regeneration research. vol 13. issue 11. 2020-10-01. PMID:30233075. |
western blot assay was used to determine expression levels of glutamate ionotropic receptor nmda type subunit 2a (glun2a) and glun2b in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Dong Ho Woo, Jin Young Bae, Min-Ho Nam, Heeyoung An, Yeon Ha Ju, Joungha Won, Jae Hyouk Choi, Eun Mi Hwang, Kyung-Seok Han, Yong Chul Bae, C Justin Le. Activation of Astrocytic μ-opioid Receptor Elicits Fast Glutamate Release Through TREK-1-Containing K2P Channel in Hippocampal Astrocytes. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30319359. |
activation of astrocytic μ-opioid receptor elicits fast glutamate release through trek-1-containing k2p channel in hippocampal astrocytes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Saju Balakrishnan, Sergej L Mirono. CA1 Neurons Acquire Rett Syndrome Phenotype After Brief Activation of Glutamatergic Receptors: Specific Role of mGluR1/5. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30386209. |
we recently reported (balakrishnan and mironov, 2018a,b) that the rtt hippocampus consistently demonstrates repetitive glutamate transients that parallel the burst firing in the ca1 neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Saju Balakrishnan, Sergej L Mirono. CA1 Neurons Acquire Rett Syndrome Phenotype After Brief Activation of Glutamatergic Receptors: Specific Role of mGluR1/5. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30386209. |
we imaged glutamate with a fluorescence sensor (iglusnfr) expressed in ca1 neurons in hippocampal organotypic slices from wild-type (wt) and mecp2 |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiaobing Chen, Christine Winters, Virginia Crocker, Michael Lazarou, Alioscka A Sousa, Richard D Leapman, Thomas S Rees. Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography. Frontiers in neuroanatomy. vol 12. 2020-10-01. PMID:30581381. |
when freeze-substituted hippocampal cultures in plastic sections are imaged by em tomography, detailed structures emerging from 3d reconstructions reveal putative glutamate receptors and membrane-associated filaments containing scaffolding proteins such as postsynaptic density (psd)-95 family proteins based on their size, shape, and known distributions. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ning Li, Yang Li, Li-Juan Li, Ke Zhu, Yan Zheng, Xiao-Min Wan. Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer's disease. Neural regeneration research. vol 14. issue 6. 2020-10-01. PMID:30762016. |
glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of alzheimer's disease. |
2020-10-01 |
2023-08-13 |
mouse |
| Michele Malaguarnera, Marta Llansola, Tiziano Balzano, Belén Gómez-Giménez, Carles Antúnez-Muñoz, Núria Martínez-Alarcón, Rahebeh Mahdinia, Vicente Felip. Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:30858801. |
the effects of bicuculline on microglia and astrocyte activation, il-1β content, on membrane expression of ampa and nmda glutamate receptors subunits in the hippocampus and on spatial learning and memory as well as anxiety were assessed. |
2020-10-01 |
2023-08-13 |
rat |
| Paul Allen, Holly Moore, Cheryl M Corcoran, James Gilleen, Petya Kozhuharova, Avi Reichenberg, Dolores Malaspin. Emerging Temporal Lobe Dysfunction in People at Clinical High Risk for Psychosis. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31133894. |
dysfunction in the medial temporal lobe, particularly the hippocampus, is linked to dysregulation of glutamate and dopamine |
2020-10-01 |
2023-08-13 |
Not clear |
| Valentyna Dubovyk, Denise Manahan-Vaugha. Distinct Time-Course of Alterations of Groups I and II Metabotropic Glutamate Receptor and GABAergic Receptor Expression Along the Dorsoventral Hippocampal Axis in an Animal Model of Psychosis. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31139061. |
distinct time-course of alterations of groups i and ii metabotropic glutamate receptor and gabaergic receptor expression along the dorsoventral hippocampal axis in an animal model of psychosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| I Chang Su, Chi Feng Hung, Chun Nan Lin, Shu Kuei Huang, Su Jane Wan. Cycloheterophyllin Inhibits the Release of Glutamate from Nerve Terminals of the Rat Hippocampus. Chemical research in toxicology. vol 32. issue 8. 2020-10-01. PMID:31264847. |
cycloheterophyllin inhibits the release of glutamate from nerve terminals of the rat hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Dylan P Quinn, Annette Kolar, Sydney A Harris, Michael Wigerius, James P Fawcett, Stefan R Kruege. The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31316356. |
to clarify the role of activity in synapse turnover, we have assessed the effects of inhibition of glutamate release from a sparse subset of cultured hippocampal neurons on synapse turnover. |
2020-10-01 |
2023-08-13 |
Not clear |
| Teresa Muro-García, Soraya Martín-Suárez, Nelson Espinosa, Roberto Valcárcel-Martín, Ainhoa Marinas, Laura Zaldumbide, Lara Galbarriatu, Amanda Sierra, Pablo Fuentealba, Juan Manuel Encina. Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala. Frontiers in cell and developmental biology. vol 7. 2020-10-01. PMID:31482091. |
in a mouse model of mesial temporal lobe epilepsy (mtle), seizures triggered by the intrahippocampal injection of the glutamate receptor agonist kainic acid (ka) induce nscs to convert into reactive nscs (react-nscs) which stop producing new neurons and ultimately generate reactive astrocytes thus contributing to the development of hippocampal sclerosis and abolishing neurogenesis. |
2020-10-01 |
2023-08-13 |
mouse |
| Yuan Li, Xin Zhang, Lixin Chen, Bo Yang, Rubo Su. Cerebellar fastigial nucleus is involved in post-stroke depression through direct cerebellar-hypothalamic GABAergic and glutamatergic projections. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555378. |
in addition, the expression of cytokines in hippocampal tissues, and the content of glutamate and gaba in the lateral hypothalamic area (lha) were measured. |
2020-10-01 |
2023-08-13 |
rat |
| Lucia Ciranna, Lara Cost. Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Hippocampal Synaptic Transmission and Plasticity: New Therapeutic Suggestions for Fragile X Syndrome. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31827422. |
in this context, results from our laboratory demonstrate that pacap rescued metabotropic glutamate receptor-mediated synaptic plasticity in the hippocampus of a mouse model of fragile x syndrome (fxs), a genetic form of intellectual disability. |
2020-10-01 |
2023-08-13 |
mouse |
| Soraya Wilke Saliba, Tiziana Bonifacino, Tsvetan Serchov, Giambattista Bonanno, Antônio Carlos Pinheiro de Oliveira, Bernd L Fiebic. Neuroprotective Effect of AM404 Against NMDA-Induced Hippocampal Excitotoxicity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31920563. |
moreover, to comprehend the mechanism of excitotoxicity, we evaluated the effects of am404 on glutamate release in hippocampal synaptosomes and the nmda-induced calcium responses in acute hippocampal slices. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sherry Dadsetan, Tiziano Balzano, Jerónimo Forteza, Andrea Cabrera-Pastor, Lucas Taoro-Gonzalez, Vicente Hernandez-Rabaza, Sara Gil-Perotín, Laura Cubas-Núñez, José-Manuel García-Verdugo, Ana Agusti, Marta Llansola, Vicente Felip. Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy. Frontiers in molecular neuroscience. vol 9. 2020-09-30. PMID:27853420. |
taking into account these data, we hypothesized that in rats with he: (1) peripheral inflammation is a main contributor to neuroinflammation; (2) neuroinflammation in hippocampus impairs spatial learning by altering ampa and/or nmda receptors membrane expression; (3) reducing peripheral inflammation with infliximab (anti-tnf-a) would improve spatial learning; (4) this would be associated with reduced neuroinflammation and normalization of the membrane expression of glutamate receptors. |
2020-09-30 |
2023-08-13 |
rat |
| Marta Weinstoc. Prenatal stressors in rodents: Effects on behavior. Neurobiology of stress. vol 6. 2020-09-30. PMID:28229104. |
among hippocampal glutamate receptors, nr2b was the only subtype consistently reduced in association with learning deficits. |
2020-09-30 |
2023-08-13 |
mouse |
| Qing Cheng, Sang-Ho Song, George J Augustin. Calcium-Dependent and Synapsin-Dependent Pathways for the Presynaptic Actions of BDNF. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28392759. |
we used cultured hippocampal neurons to determine the signaling pathways mediating brain-derived neurotrophic factor (bdnf) regulation of spontaneous glutamate and gaba release. |
2020-09-30 |
2023-08-13 |
mouse |
| Michelle D Gjørlund, Eva M M Carlsen, Andreas B Kønig, Oksana Dmytrieva, Anders V Petersen, Jacob Jacobsen, Vladimir Berezin, Jean-François Perrier, Sylwia Owczare. Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28515678. |
in a slice preparation from the hippocampus of mice, nl1 inhibited the release of glutamate from mossy fibers that project to ca3 pyramidal neurons. |
2020-09-30 |
2023-08-13 |
mouse |