| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Sierra-Paredes, J Galán-Valiente, M D Vazquez-Illanes, E Aguilar-Veiga, G Sierra-Marcuñ. Effect of ionotropic glutamate receptors antagonists on the modifications in extracellular glutamate and aspartate levels during picrotoxin seizures: a microdialysis study in freely moving rats. Neurochemistry international. vol 37. issue 4. 2000-10-02. PMID:10825578. |
in this paper, we study the effect of continuous hippocampal microperfusion of the nmda, ampa and kainate glutamate receptor inhibitors 5-methyl-10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5, 10-imine (mk-801); 6,7-dinitroquinoxaline-2,3-dione (dnqx), and 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5h-2,3-benzodiazepine hydrochloride (gyki 52466). |
2000-10-02 |
2023-08-12 |
rat |
| J M Dubinsky, N Brustovetsky, V Pinelis, B S Kristal, C Herman, X L. The mitochondrial permeability transition: the brain's point of view. Biochemical Society symposium. vol 66. 2000-09-26. PMID:10989659. |
in hippocampal neurons, mpt induction was observed upon introduction of calcium and ionophore or application of toxic doses of glutamate. |
2000-09-26 |
2023-08-12 |
Not clear |
| E Vereker, V Campbell, E Roche, E McEntee, M A Lync. Lipopolysaccharide inhibits long term potentiation in the rat dentate gyrus by activating caspase-1. The Journal of biological chemistry. vol 275. issue 34. 2000-09-25. PMID:10856294. |
we report that intraperitoneal injection of lipopolysaccharide increased hippocampal caspase-1 activity and il-1beta concentration; these changes were associated with increased activity of the stress-activated kinase c-jun nh(2)-terminal kinase, decreased glutamate release, and impaired long term potentiation. |
2000-09-25 |
2023-08-12 |
rat |
| H Matthies, H Schroeder, K H Smalla, M Kru. Enhancement of glutamate release by L-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 4. 2000-09-21. PMID:10940323. |
enhancement of glutamate release by l-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. |
2000-09-21 |
2023-08-12 |
rat |
| H Matthies, H Schroeder, K H Smalla, M Kru. Enhancement of glutamate release by L-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 4. 2000-09-21. PMID:10940323. |
coapplication of 0.2 mm l-fucose with the competitive n-methyl-d-aspartate (nmda) receptor antagonist, d-2-amino-5-phosphonovalerate (ap5), or coapplication of 0.2 mm l-fucose in the presence of an inhibitor for class i/ii metabotropic glutamate receptors, (s)-alpha-methyl-4-carboxyphenylglycine (mcpg), reversed ltp blockade in the ca1-region of hippocampal slices. |
2000-09-21 |
2023-08-12 |
rat |
| J F Martinez-Tica, M H Zorno. Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924682. |
the data derived from this study indicates that the acute administration of such agents had no effect on ischemia-induced glutamate release within the hippocampus under these experimental conditions. |
2000-09-20 |
2023-08-12 |
rabbit |
| C Sommer, S U Roth, R Kuhn, M Kiesslin. Metabotropic glutamate receptor subtypes are differentially expressed after transient cerebral ischemia without, during and after tolerance induction in the gerbil hippocampus. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924689. |
metabotropic glutamate receptor subtypes are differentially expressed after transient cerebral ischemia without, during and after tolerance induction in the gerbil hippocampus. |
2000-09-20 |
2023-08-12 |
Not clear |
| N S Butters, M A Gibson, J N Reynolds, J F Brie. Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig. Alcohol (Fayetteville, N.Y.). vol 21. issue 1. 2000-09-20. PMID:10946152. |
effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig. |
2000-09-20 |
2023-08-12 |
Not clear |
| N S Butters, M A Gibson, J N Reynolds, J F Brie. Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig. Alcohol (Fayetteville, N.Y.). vol 21. issue 1. 2000-09-20. PMID:10946152. |
on pd 12, the 45 mm k(+)- and 10 microm veratridine-stimulated release of glutamate in transverse hippocampal slices was decreased in the ethanol group compared with the two control groups. |
2000-09-20 |
2023-08-12 |
Not clear |
| N S Butters, M A Gibson, J N Reynolds, J F Brie. Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig. Alcohol (Fayetteville, N.Y.). vol 21. issue 1. 2000-09-20. PMID:10946152. |
this alteration in glutamate release produced by chronic prenatal ethanol exposure may decrease the efficiency of excitatory synaptic transmission in the hippocampus during postnatal life. |
2000-09-20 |
2023-08-12 |
Not clear |
| S Gasparini, C Saviane, L L Voronin, E Cherubin. Silent synapses in the developing hippocampus: lack of functional AMPA receptors or low probability of glutamate release? Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 17. 2000-09-19. PMID:10931951. |
silent synapses in the developing hippocampus: lack of functional ampa receptors or low probability of glutamate release? |
2000-09-19 |
2023-08-12 |
Not clear |
| E Aronica, E A van Vliet, O A Mayboroda, D Troost, F H da Silva, J A Gorte. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. The European journal of neuroscience. vol 12. issue 7. 2000-09-19. PMID:10947812. |
because astrocytes express glutamate receptors, we examined changes in metabotropic glutamate receptor (mglur) 2/3, mglur5 and transforming growth factor (tgf)-beta in glial cells of the hippocampal regions in an experimental rat model of spontaneous seizures. |
2000-09-19 |
2023-08-12 |
rat |
| C Perego, C Vanoni, M Bossi, S Massari, H Basudev, R Longhi, G Pietrin. The GLT-1 and GLAST glutamate transporters are expressed on morphologically distinct astrocytes and regulated by neuronal activity in primary hippocampal cocultures. Journal of neurochemistry. vol 75. issue 3. 2000-09-12. PMID:10936189. |
the glt-1 and glast glutamate transporters are expressed on morphologically distinct astrocytes and regulated by neuronal activity in primary hippocampal cocultures. |
2000-09-12 |
2023-08-12 |
rat |
| D L Pettit, G J Augustin. Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons. Journal of neurophysiology. vol 84. issue 1. 2000-09-07. PMID:10899180. |
to map the location of functional glutamate and gaba receptors on individual hippocampal neurons, we photolyzed "caged" glutamate and gaba while measuring the electrical currents resulting from activation of these receptors. |
2000-09-07 |
2023-08-12 |
Not clear |
| J Behr, T Gloveli, D Schmitz, U Heineman. Dopamine depresses excitatory synaptic transmission onto rat subicular neurons via presynaptic D1-like dopamine receptors. Journal of neurophysiology. vol 84. issue 1. 2000-09-07. PMID:10899189. |
the results indicate that da strongly depresses the hippocampal and the entorhinal excitatory input onto subicular neurons by decreasing the glutamate release following activation of presynaptic d1-like da receptors. |
2000-09-07 |
2023-08-12 |
rat |
| A M Mazarati, J G Hohmann, A Bacon, H Liu, R Sankar, R A Steiner, D Wynick, C G Wasterlai. Modulation of hippocampal excitability and seizures by galanin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 16. 2000-08-31. PMID:10934278. |
depolarization-induced glutamate release from hippocampal slices was greater in galko and lower in galoe, suggesting that alterations of physiological and seizure responses in galanin transgenic animals may be mediated through modulation of glutamate release. |
2000-08-31 |
2023-08-12 |
mouse |
| O Miyamoto, K Sumitani, T Nakamura, S Yamagami, S Miyata, T Itano, T Negi, A Okab. Clostridium perfringens epsilon toxin causes excessive release of glutamate in the mouse hippocampus. FEMS microbiology letters. vol 189. issue 1. 2000-08-29. PMID:10913875. |
clostridium perfringens epsilon toxin causes excessive release of glutamate in the mouse hippocampus. |
2000-08-29 |
2023-08-12 |
mouse |
| O Miyamoto, K Sumitani, T Nakamura, S Yamagami, S Miyata, T Itano, T Negi, A Okab. Clostridium perfringens epsilon toxin causes excessive release of glutamate in the mouse hippocampus. FEMS microbiology letters. vol 189. issue 1. 2000-08-29. PMID:10913875. |
microdialysis revealed that epsilon toxin induced excessive glutamate release in the hippocampus. |
2000-08-29 |
2023-08-12 |
mouse |
| O Miyamoto, K Sumitani, T Nakamura, S Yamagami, S Miyata, T Itano, T Negi, A Okab. Clostridium perfringens epsilon toxin causes excessive release of glutamate in the mouse hippocampus. FEMS microbiology letters. vol 189. issue 1. 2000-08-29. PMID:10913875. |
both the seizure and glutamate release were attenuated by prior injection with riluzole, an inhibitor of pre-synaptic glutamate release, suggesting that this toxin enhances glutamate efflux, leading to seizure and hippocampal neuronal damage. |
2000-08-29 |
2023-08-12 |
mouse |
| M P Johnson, G M Kelly, M Chamberlai. Blockade of pilocarpine-induced cerebellar phosphoinositide hydrolysis with metabotropic glutamate antagonists: evidence for an indirect control of granule cell glutamate release by muscarinic agonists. Neuroscience letters. vol 285. issue 1. 2000-08-22. PMID:10788710. |
it was also found that the cerebellar but not the hippocampal pilocarpine-induced rise in pi hydrolysis could be blocked by the metabotropic glutamate (mglu) receptor antagonist, ly341495 (100 nmol, i.c.v.). |
2000-08-22 |
2023-08-12 |
rat |