| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Heim, J Zhang, J Lan, M Sieklucka, T Kurz, P Riederer, M Gerlach, K H Sonta. Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712651. |
analysis at bcca of hippocampal metabolism using microdialysis showed increased release of glutamate, aspartate and gamma-aminobutyric acid, followed by a progressive rise in the formation of hydroxyl free radicals measured as 2,3-dihydroxybenzoic acid (2,3-dhba), their reaction product with salicylate, though only in the re-perfusion phase. |
2000-05-25 |
2023-08-12 |
rat |
| G J Brewer, T W Walliman. Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. Journal of neurochemistry. vol 74. issue 5. 2000-05-25. PMID:10800940. |
protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. |
2000-05-25 |
2023-08-12 |
rat |
| G J Brewer, T W Walliman. Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. Journal of neurochemistry. vol 74. issue 5. 2000-05-25. PMID:10800940. |
in serum-free cultures, glutamate at 0.5-1 mm was toxic to embryonic hippocampal neurons. |
2000-05-25 |
2023-08-12 |
rat |
| J A van Hooft, R Giuffrida, M Blatow, H Monye. Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804195. |
differential expression of group i metabotropic glutamate receptors in functionally distinct hippocampal interneurons. |
2000-05-25 |
2023-08-12 |
Not clear |
| J A van Hooft, R Giuffrida, M Blatow, H Monye. Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804195. |
metabotropic glutamate receptors (mglurs) have been proposed to be involved in oscillatory rhythmic activity in the hippocampus. |
2000-05-25 |
2023-08-12 |
Not clear |
| N Schröder, F De-Paris, R Roesler, J H Medina, D O Souza, I Izquierd. Effect of inhibitory avoidance training on [3H]-glutamate binding in the hippocampus and parietal cortex of rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 33. issue 2. 2000-05-18. PMID:10657064. |
inhibitory avoidance training induced a 29% increase in glutamate binding in hippocampal membranes obtained from rats sacrificed at 5 min (p<0.01), but not at 0, 15, or 60 min after training, and did not affect glutamate binding in membranes obtained from the parietal cortex. |
2000-05-18 |
2023-08-12 |
rat |
| J H Meador-Woodruff, D J Heal. Glutamate receptor expression in schizophrenic brain. Brain research. Brain research reviews. vol 31. issue 2-3. 2000-05-17. PMID:10719155. |
the expression of the glutamate receptors has been determined at multiple levels of gene expression in postmortem brain samples from schizophrenics and controls; while results have not been entirely consistent from study to study, several generalizations have emerged from this literature: (1) the ampa receptor is abnormally decreased in expression in the schizophrenic hippocampus, involving decreased levels of subunit transcripts and protein levels, as well as binding sites, (2) similar changes are seen for kainate receptor expression in the hippocampus, and (3) the obligate nmda receptor subunit, nmdar1, may be abnormally expressed in some cortical regions in schizophrenia. |
2000-05-17 |
2023-08-12 |
Not clear |
| V L Raghavendra Rao, A M Rao, A Dogan, K K Bowen, J Hatcher, J D Rothstein, R J Dempse. Glial glutamate transporter GLT-1 down-regulation precedes delayed neuronal death in gerbil hippocampus following transient global cerebral ischemia. Neurochemistry international. vol 36. issue 6. 2000-05-11. PMID:10762090. |
glial glutamate transporter glt-1 down-regulation precedes delayed neuronal death in gerbil hippocampus following transient global cerebral ischemia. |
2000-05-11 |
2023-08-12 |
Not clear |
| M Stanciu, Y Wang, R Kentor, N Burke, S Watkins, G Kress, I Reynolds, E Klann, M R Angiolieri, J W Johnson, D B DeFranc. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. The Journal of biological chemistry. vol 275. issue 16. 2000-05-10. PMID:10766856. |
oxidative toxicity can be induced by glutamate treatment in cells that lack ionotrophic glutamate receptors, such as the immortalized ht22 hippocampal cell line and immature primary cortical neurons. |
2000-05-10 |
2023-08-12 |
Not clear |
| M Gottlieb, M Domercq, C Matut. Altered expression of the glutamate transporter EAAC1 in neurons and immature oligodendrocytes after transient forebrain ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 4. 2000-05-04. PMID:10779012. |
using immunohistochemical and western blot analyses, the authors examined the expression of the glutamate transporters eaac1, glast, and glt-1 in the rat hippocampus and cerebral cortex 8 hours and 1 to 28 days after transient forebrain ischemia. |
2000-05-04 |
2023-08-12 |
rat |
| E T Costa, E E Soto, R A Cardoso, D S Olivera, C F Valenzuel. Acute effects of ethanol on kainate receptors in cultured hippocampal neurons. Alcoholism, clinical and experimental research. vol 24. issue 2. 2000-05-02. PMID:10698375. |
kainate receptors are a subclass of ionotropic glutamate receptors that regulate excitability and mediate synaptic transmission and plasticity in the hippocampus. |
2000-05-02 |
2023-08-12 |
Not clear |
| B Ahlemeyer, H Beier, I Semkova, C Schaper, J Krieglstei. S-100beta protects cultured neurons against glutamate- and staurosporine-induced damage and is involved in the antiapoptotic action of the 5 HT(1A)-receptor agonist, Bay x 3702. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700604. |
in addition, s-100beta (1 ng/ml) reduced neuronal death induced by exposure to glutamate (0.25 mm, 30 min) in mixed neuronal/glial cultures from neonatal rat hippocampus. |
2000-04-25 |
2023-08-12 |
rat |
| V Mendoza-Fernández, R D Andrew, C Barajas-Lópe. ATP inhibits glutamate synaptic release by acting at P2Y receptors in pyramidal neurons of hippocampal slices. The Journal of pharmacology and experimental therapeutics. vol 293. issue 1. 2000-04-21. PMID:10734167. |
atp inhibits glutamate synaptic release by acting at p2y receptors in pyramidal neurons of hippocampal slices. |
2000-04-21 |
2023-08-12 |
Not clear |
| S N Yan. Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683565. |
ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. |
2000-04-20 |
2023-08-12 |
rat |
| S N Yan. Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683565. |
using whole-cell patch-clamp recordings, the present study examined whether ceramide modulated excitatory postsynaptic currents mediated by ionotropic glutamate receptors in ca1 pyramidal neurons of rat hippocampal slices. |
2000-04-20 |
2023-08-12 |
rat |
| S N Yan. Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683565. |
the study suggests that ceramide induces a long-term depressed modulation on synaptic transmission mediated by ionotropic glutamate receptors in the hippocampus, possibly through the activation of postsynaptic protein phosphatases 1 and 2a. |
2000-04-20 |
2023-08-12 |
rat |
| A Kelly, M A Lync. Long-term potentiation in dentate gyrus of the rat is inhibited by the phosphoinositide 3-kinase inhibitor, wortmannin. Neuropharmacology. vol 39. issue 4. 2000-04-20. PMID:10728885. |
the results presented demonstrate that wortmannin also exerted an inhibitory effect on kcl-stimulated glutamate release and calcium influx in hippocampal synaptosomes in vitro. |
2000-04-20 |
2023-08-12 |
rat |
| C Plachez, N C Danbolt, M Récasen. Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurons in primary culture. Journal of neuroscience research. vol 59. issue 5. 2000-04-18. PMID:10686586. |
transient expression of the glial glutamate transporters glast and glt in hippocampal neurons in primary culture. |
2000-04-18 |
2023-08-12 |
Not clear |
| C Plachez, N C Danbolt, M Récasen. Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurons in primary culture. Journal of neuroscience research. vol 59. issue 5. 2000-04-18. PMID:10686586. |
here we have studied the expression of the glutamate transporters glast, glt and eaac during the in vitro development of embryonic hippocampal neurons grown in a defined (serum free) medium. |
2000-04-18 |
2023-08-12 |
Not clear |
| H Tumani, A Smirnov, S Barchfeld, U Olgemöller, K Maier, P Lange, W Brück, R Na. Inhibition of glutamine synthetase in rabbit pneumococcal meningitis is associated with neuronal apoptosis in the dentate gyrus. Glia. vol 30. issue 1. 2000-04-18. PMID:10696140. |
in conclusion, the inability of hippocampal glutamine synthetase to metabolize excess amounts of glutamate may contribute to neuronal apoptosis in the hippocampal formation during meningitis. |
2000-04-18 |
2023-08-12 |
rabbit |