| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L D Partridge, C F Valenzuel. Ca2+ store-dependent potentiation of Ca2+-activated non-selective cation channels in rat hippocampal neurones in vitro. The Journal of physiology. vol 521 Pt 3. 2000-08-21. PMID:10601493. |
can channels were activated by ip3-dependent ca2+ release following metabotropic glutamate receptor (mglur) stimulation either by schaffer collateral input to ca1 neurones in brain slices in which ionotropic glutamate and gabaa receptors, k+ channels, and the na+-ca2+ exchanger were blocked or by application of the mglur antagonist acpd in cultured hippocampal neurones. |
2000-08-21 |
2023-08-12 |
human |
| F Youssef, T W Stone, J I Adda. Interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice. European journal of pharmacology. vol 398. issue 3. 2000-08-21. PMID:10862824. |
interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice. |
2000-08-21 |
2023-08-12 |
rat |
| F Youssef, T W Stone, J I Adda. Interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice. European journal of pharmacology. vol 398. issue 3. 2000-08-21. PMID:10862824. |
since long-term potentiation is believed to involve activation of amino acid receptors, we have now sought to determine whether long-term potentiation can modify the sensitivity of neurones to glutamate receptor agonists in rat hippocampal slices. |
2000-08-21 |
2023-08-12 |
rat |
| F Youssef, T W Stone, J I Adda. Interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice. European journal of pharmacology. vol 398. issue 3. 2000-08-21. PMID:10862824. |
the results indicate that long-term potentiation can modify the sensitivity of hippocampal neurones to glutamate receptor agonists, and that differences exist in the pharmacology of nmda and quinolinic acid. |
2000-08-21 |
2023-08-12 |
rat |
| Y Takahashi, K Tsunashima, M Sadamatsu, C Schwarzer, S Amano, N Ihara, M Sasa, N Kato, G Sper. Altered hippocampal expression of neuropeptide Y, somatostatin, and glutamate decarboxylase in Ihara's epileptic rats and spontaneously epileptic rats. Neuroscience letters. vol 287. issue 2. 2000-08-17. PMID:10854723. |
altered hippocampal expression of neuropeptide y, somatostatin, and glutamate decarboxylase in ihara's epileptic rats and spontaneously epileptic rats. |
2000-08-17 |
2023-08-12 |
rat |
| Y Takahashi, K Tsunashima, M Sadamatsu, C Schwarzer, S Amano, N Ihara, M Sasa, N Kato, G Sper. Altered hippocampal expression of neuropeptide Y, somatostatin, and glutamate decarboxylase in Ihara's epileptic rats and spontaneously epileptic rats. Neuroscience letters. vol 287. issue 2. 2000-08-17. PMID:10854723. |
by in situ hybridization and immunocytochemistry, expression of neuropeptide y (npy), somatostatin and glutamate decarboxylase 65 (gad65) was studied in the hippocampus of two different epileptic mutant rats, ihara's epileptic rat (ier) and the spontaneously epileptic rat (ser). |
2000-08-17 |
2023-08-12 |
rat |
| T Bruhn, L M Levy, M Nielsen, T Christensen, F F Johansen, N H Dieme. Ischemia induced changes in expression of the astrocyte glutamate transporter GLT1 in hippocampus of the rat. Neurochemistry international. vol 37. issue 2-3. 2000-08-14. PMID:10812213. |
ischemia induced changes in expression of the astrocyte glutamate transporter glt1 in hippocampus of the rat. |
2000-08-14 |
2023-08-12 |
rat |
| L A Izquierdo, D M Barros, P G Ardenghi, P Pereira, C Rodrigues, H Choi, J H Medina, I Izquierd. Different hippocampal molecular requirements for short- and long-term retrieval of one-trial avoidance learning. Behavioural brain research. vol 111. issue 1-2. 2000-08-10. PMID:10840135. |
ten minutes prior to the retention test, through indwelling cannulae placed in the ca1 region of the dorsal hippocampus, they received 0.5 microl infusions of: saline, a vehicle (2% dimethylsulfoxide in saline), the glutamate nmda receptor blocker, aminophosphonopentanoic acid (ap5) (5.0 microg), the ampa/kainate receptor blocker, cyanonitroquinoxaline dione (cnqx) (0.25 or 1.25 microg), the metabotropic receptor antagonist, methylcarboxyphenylglycine (mcpg) (0.5 or 2.5 microg), the inhibitor of calcium/calmodulin-dependent protein kinase ii (kn62) (3.5 microg), the inhibitor of camp-dependent protein kinase (pka), rp-camps (0.1 or 0.5 microg), the stimulant of the same enzyme, sp-camps (0.1 or 0.5 microg), or the inhibitor of the mitogen-activated protein kinase (mapk) kinase, pd098059 (10 or 50 microm). |
2000-08-10 |
2023-08-12 |
rat |
| C M Luetjens, N T Bui, B Sengpiel, G Münstermann, M Poppe, A J Krohn, E Bauerbach, J Krieglstein, J H Preh. Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2000-08-10. PMID:10908611. |
we monitored intracellular superoxide production of hippocampal neurons during and after exposure to the glutamate receptor agonist nmda (300 microm). |
2000-08-10 |
2023-08-12 |
human |
| Y Adamchik, M V Frantseva, M Weisspapir, P L Carlen, J L Perez Velazque. Methods to induce primary and secondary traumatic damage in organotypic hippocampal slice cultures. Brain research. Brain research protocols. vol 5. issue 2. 2000-08-02. PMID:10775835. |
3538-3553; d.w. newell, a. barth, v. papermaster, a.t. malouf, glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures, j. neurosci. |
2000-08-02 |
2023-08-12 |
rat |
| Y Adamchik, M V Frantseva, M Weisspapir, P L Carlen, J L Perez Velazque. Methods to induce primary and secondary traumatic damage in organotypic hippocampal slice cultures. Brain research. Brain research protocols. vol 5. issue 2. 2000-08-02. PMID:10775835. |
carlen, in vitro ischemia promotes glutamate mediated free radical generation and intracellular calcium accumulation in pyramidal neurons of cultured hippocampal slices, j. neurosci. |
2000-08-02 |
2023-08-12 |
rat |
| G Zhao, M P Flavi. Differential sensitivity of rat hippocampal and cortical astrocytes to oxygen-glucose deprivation injury. Neuroscience letters. vol 285. issue 3. 2000-08-01. PMID:10806315. |
selective vulnerability of hippocampal neurons to ischemia is felt to relate to intense glutamatergic input and glutamate receptor expression. |
2000-08-01 |
2023-08-12 |
rat |
| J M Sulliva. Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 3. 2000-08-01. PMID:10837502. |
cannabinoids reduce glutamate release through a g-protein-mediated inhibition of the calcium channels responsible for neurotransmitter release from hippocampal neurons. |
2000-08-01 |
2023-08-12 |
Not clear |
| E D Kirson, Y Yaar. Unique properties of NMDA receptors enhance synaptic excitation of radiatum giant cells in rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 13. 2000-07-26. PMID:10864941. |
in the hippocampus, fast excitatory synaptic transmission of principal projection neurons is mediated by non-nmda glutamate receptors, whereas nmda glutamate receptors serve a slower modulatory role. |
2000-07-26 |
2023-08-12 |
rat |
| G Hoogland, J J Hens, M De Wit, C W van Veelen, A C van Huffelen, W H Gispen, P N de Graa. Glutamate and gamma-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients. Journal of neuroscience research. vol 60. issue 5. 2000-07-24. PMID:10820440. |
hippocampal synaptosomes from mts-associated tle patients, unlike those from t-associated tle patients, contained about 70% less glutamate and 55% less gaba than neocortical synaptosomes. |
2000-07-24 |
2023-08-12 |
human |
| X M Gao, K Sakai, R C Roberts, R R Conley, B Dean, C A Tamming. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. The American journal of psychiatry. vol 157. issue 7. 2000-07-19. PMID:10873924. |
ionotropic glutamate receptors and expression of n-methyl-d-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. |
2000-07-19 |
2023-08-12 |
human |
| M Lousa, S Sanchez-Alonso, R Rodriguez-Diaz, J Dalma. Status epilepticus with neuron-reactive serum antibodies: response to plasma exchange. Neurology. vol 54. issue 11. 2000-07-13. PMID:10851386. |
the patient's serum reacted with rat cerebral cortex, hippocampus, and cerebellum, but not with cells expressing the glutamate receptor glur3. |
2000-07-13 |
2023-08-12 |
rat |
| S Lankiewicz, C Marc Luetjens, N Truc Bui, A J Krohn, M Poppe, G M Cole, T C Saido, J H Preh. Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death. The Journal of biological chemistry. vol 275. issue 22. 2000-07-11. PMID:10828077. |
exposure of cultured rat hippocampal neurons to the selective glutamate receptor agonist n-methyl-d-aspartate (300 microm, 5 min) or to the apoptosis-inducing protein kinase inhibitor staurosporine (300 nm) induced a delayed neuron death. |
2000-07-11 |
2023-08-12 |
rat |
| Q Zhou, C C Petersen, R A Nicol. Effects of reduced vesicular filling on synaptic transmission in rat hippocampal neurones. The Journal of physiology. vol 525 Pt 1. 2000-07-10. PMID:10811737. |
the consequence of reduced uptake of neurotransmitters into synaptic vesicles on synaptic transmission was examined in rat hippocampal slices and culture using bafilomycin a1 (baf), a potent and specific blocker of the vacuolar-type (v-type) atpase, which eliminates the driving force for the uptake of both glutamate and gaba into synaptic vesicles. |
2000-07-10 |
2023-08-12 |
rat |
| T W Margrie, J A Rostas, P Sa. Inhibition of transmitter release and long-term depression in the avian hippocampus. Neuroscience letters. vol 284. issue 1-2. 2000-07-03. PMID:10771151. |
here using whole cell and intracellular recordings from brain slices, we show that the n-type calcium channel contributes significantly to glutamate release in the avian hippocampus. |
2000-07-03 |
2023-08-12 |
Not clear |