| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G M Khan, I Smolders, G Ebinger, Y Michott. Flumazenil prevents diazepam-elicited anticonvulsant action and concomitant attenuation of glutamate overflow. European journal of pharmacology. vol 407. issue 1-2. 2000-12-29. PMID:11050301. |
the anticonvulsant effect was associated with significant attenuation of pilocarpine-evoked increases in extracellular hippocampal glutamate levels to below the baseline levels. |
2000-12-29 |
2023-08-12 |
rat |
| Y Ueda, L J Willmor. Molecular regulation of glutamate and GABA transporter proteins by valproic acid in rat hippocampus during epileptogenesis. Experimental brain research. vol 133. issue 3. 2000-12-28. PMID:10958523. |
molecular regulation of glutamate and gaba transporter proteins by valproic acid in rat hippocampus during epileptogenesis. |
2000-12-28 |
2023-08-12 |
rat |
| Y Ueda, L J Willmor. Molecular regulation of glutamate and GABA transporter proteins by valproic acid in rat hippocampus during epileptogenesis. Experimental brain research. vol 133. issue 3. 2000-12-28. PMID:10958523. |
regions of the hippocampus were assayed for glutamate and gaba transporters by western blot. |
2000-12-28 |
2023-08-12 |
rat |
| H Li, J L Henr. Adenosine action on interneurons and synaptic transmission onto interneurons in rat hippocampus in vitro. European journal of pharmacology. vol 407. issue 3. 2000-12-27. PMID:11068019. |
thus, as adenosine is released during ischemia and epilepsy, adenosine may protect both interneurons and pyramidal cells from glutamate excitotoxicity through activation of adenosine a1 receptors on these neurons in the hippocampus. |
2000-12-27 |
2023-08-12 |
rat |
| G Zhu, M Okada, T Murakami, A Kamata, Y Kawata, K Wada, S Kanek. Dysfunction of M-channel enhances propagation of neuronal excitability in rat hippocampus monitored by multielectrode dish and microdialysis systems. Neuroscience letters. vol 294. issue 1. 2000-12-22. PMID:11044585. |
to explore the pathogenesis of benign familial neonatal convulsions (bfnc), we determined effects of kcnq-related m-channels (kcnq-channels) on hippocampal glutamate (glu) and gamma-aminobutyric acid (gaba) releases using microdialysis, and propagation of evoked field-potentials (fp) using multielectrode (64-ch)-dish system as two-dimensional monitoring. |
2000-12-22 |
2023-08-12 |
rat |
| C E Loscher, S Donnelly, K H Mills, M A Lync. Interleukin-1beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine. Journal of neuroimmunology. vol 111. issue 1-2. 2000-12-22. PMID:11063823. |
in this study we report that il-1beta concentrations were significantly increased in the hippocampus following subcutaneous (s.c.) injection of pw, and that this was accompanied by increased activity of the stress-activated kinase, c-jun-n-terminal kinase (jnk) and a decrease in glutamate release. |
2000-12-22 |
2023-08-12 |
Not clear |
| C E Loscher, S Donnelly, K H Mills, M A Lync. Interleukin-1beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine. Journal of neuroimmunology. vol 111. issue 1-2. 2000-12-22. PMID:11063823. |
incubation of hippocampal synaptosomes in the presence of pw, pt or lps also resulted in increased jnk activation and decreased glutamate release, effects which were mimicked by il-1beta and blocked by the il-1 receptor antagonist (il-ra). |
2000-12-22 |
2023-08-12 |
Not clear |
| M Cammarota, M L de Stein, G Paratcha, L R Bevilaqua, I Izquierdo, J H Medin. Rapid and transient learning-associated increase in NMDA NR1 subunit in the rat hippocampus. Neurochemical research. vol 25. issue 5. 2000-12-20. PMID:10905617. |
here we report on the effect of a one trial inhibitory avoidance training in rats, a hippocampal-dependent learning task, on the levels of different subunits of the glutamate nmda receptor in synaptic plasma membranes (spm) isolated from the hippocampus. |
2000-12-20 |
2023-08-12 |
rat |
| F Ventriglia, V Di Mai. A Brownian simulation model of glutamate synaptic diffusion in the femtosecond time scale. Biological cybernetics. vol 83. issue 2. 2000-12-11. PMID:10966049. |
to gain a better understanding of the elementary unit of synaptic communication between hippocampal neurons, we simulated the release of glutamate from a single pre-synaptic vesicle and its diffusion into the synaptic cleft. |
2000-12-11 |
2023-08-12 |
Not clear |
| R M Sapolsk. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063972. |
as such, the first half of this article reviews current knowledge about how hippocampal neurons die during insults, focusing on issues related to the trafficking of glutamate and calcium, glutamate receptor subtypes, oxygen radical generation, programmed cell death, and neuronal defenses. |
2000-12-07 |
2023-08-12 |
Not clear |
| M Müller, G G Somje. Na(+) dependence and the role of glutamate receptors and Na(+) channels in ion fluxes during hypoxia of rat hippocampal slices. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024079. |
na(+) dependence and the role of glutamate receptors and na(+) channels in ion fluxes during hypoxia of rat hippocampal slices. |
2000-11-30 |
2023-08-12 |
rat |
| b' T G Hedberg, E F Sperber, J Vel\\xc3\\xadskov\\xc3\\xa1, S L Mosh\\xc3\\xa. Laminar and temporal heterogeneity of NMDA/metabotropic glutamate receptor binding in posterior cingulate cortex. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024080.' |
interpreted in accordance with our physiologically derived models of hippocampo-cortical microcircuitry, these results suggest that spatial and temporal variations in glutamate receptor distribution may play an important role in intracingulate neural processing of afferent input from hippocampus. |
2000-11-30 |
2023-08-12 |
rat |
| R Fabian-Fine, W Volknandt, A Fine, M G Stewar. Age-dependent pre- and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029638. |
here, using postembedding immunogold labelling, we describe the ultrastructural distribution of ampa-type glutamate receptors (glur1-4) in ca3 stratum radiatum of organotypic hippocampal slice cultures at 10 days to 11 weeks in vitro and compare the labelling with intact brain of corresponding age. |
2000-11-30 |
2023-08-12 |
rat |
| G Szabó, Z Kartarova, B Hoertnagl, R Somogyi, G Sper. Differential regulation of adult and embryonic glutamate decarboxylases in rat dentate granule cells after kainate-induced limbic seizures. Neuroscience. vol 100. issue 2. 2000-11-28. PMID:11008167. |
to study the seizure-induced activation of glutamate decarboxylase, we investigated the expression of both embryonic and adult glutamate decarboxylase messenger rnas in the adult rat hippocampus after kainic acid administration by semi-quantitative reverse transcription-coupled polymerase chain reaction, in situ hybridization and immunoblotting. |
2000-11-28 |
2023-08-12 |
rat |
| D J Healy, J H Meador-Woodruf. Ionotropic glutamate receptor modulation preferentially affects NMDA receptor expression in rat hippocampus. Synapse (New York, N.Y.). vol 38. issue 3. 2000-11-28. PMID:11020232. |
ionotropic glutamate receptor modulation preferentially affects nmda receptor expression in rat hippocampus. |
2000-11-28 |
2023-08-12 |
rat |
| D J Healy, J H Meador-Woodruf. Ionotropic glutamate receptor modulation preferentially affects NMDA receptor expression in rat hippocampus. Synapse (New York, N.Y.). vol 38. issue 3. 2000-11-28. PMID:11020232. |
in order to address the mutual regulation of nmda, ampa, and kainate receptor expression in rat hippocampus, we conducted two experiments examining the effects of nmda and non-nmda glutamate receptor modulators on nmda, ampa, and kainate receptor expression using in situ hybridization and receptor autoradiography. |
2000-11-28 |
2023-08-12 |
rat |
| R S Greenwood, Z Fan, R McHugh, R Meeke. Inhibition of hippocampal kindling by metabotropic glutamate receptor antisense oligonucleotides. Molecular and cellular neurosciences. vol 16. issue 3. 2000-11-21. PMID:10995550. |
inhibition of hippocampal kindling by metabotropic glutamate receptor antisense oligonucleotides. |
2000-11-21 |
2023-08-12 |
rat |
| M R Vianna, M Alonso, H Viola, J Quevedo, F de Paris, M Furman, M L de Stein, J H Medina, I Izquierd. Role of hippocampal signaling pathways in long-term memory formation of a nonassociative learning task in the rat. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040265. |
the immediate posttraining bilateral infusion of cnqx (1 microg/side), an ampa/kainate glutamate receptor antagonist, or of muscimol (0.03 microg/side), a gaba(a) receptor agonist, into the ca1 region of the dorsal hippocampus impaired long-term memory of habituation. |
2000-11-21 |
2023-08-12 |
rat |
| B M McGahon, D S Martin, D F Horrobin, M A Lync. Age-related changes in LTP and antioxidant defenses are reversed by an alpha-lipoic acid-enriched diet. Neurobiology of aging. vol 20. issue 6. 2000-11-17. PMID:10674431. |
among the age-related changes identified in rat hippocampus are impairments in ltp and glutamate release. |
2000-11-17 |
2023-08-12 |
rat |
| G M Khan, I Smolders, G Ebinger, Y Michott. Anticonvulsant effect and neurotransmitter modulation of focal and systemic 2-chloroadenosine against the development of pilocarpine-induced seizures. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974326. |
the attenuation of pilocarpine-induced dopamine efflux and the late elevations of glutamate are likely to be mediated by hippocampal a(2a) receptors. |
2000-11-13 |
2023-08-12 |
rat |