| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A K Shetty, D A Turne. Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102487. |
it also leads to persistent reductions in hippocampal glutamate decarboxylase (gad) interneuron numbers without diminution in nissl-stained interneuron numbers, indicating loss of gad expression in a majority of interneurons. |
2001-02-08 |
2023-08-12 |
rat |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
in the hippocampus, gaba(a)r agonists suppressed amplitudes, but not frequency, of spfps, whereas glutamate antagonists suppressed frequency but not amplitudes. |
2001-02-08 |
2023-08-12 |
mouse |
| S Pogun, S Demirgoren, D Taskiran, L Kanit, O Yilmaz, E O Koylu, B Balkan, E D Londo. Nicotine modulates nitric oxide in rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115736. |
while nicotine appeared to increase no indirectly via glutamate receptors in the cortex and hippocampus, this was not true of the corpus striatum, where blocking nmda-type glutamate receptors with mk-801 had no effect. |
2001-02-08 |
2023-08-12 |
rat |
| Y Ueda, T Doi, J Tokumaru, Y Mitsuyama, L J Willmor. Kindling phenomena induced by the repeated short-term high potassium stimuli in the ventral hippocampus of rats: on-line monitoring of extracellular glutamate overflow. Experimental brain research. vol 135. issue 2. 2001-02-08. PMID:11131504. |
kindling phenomena induced by the repeated short-term high potassium stimuli in the ventral hippocampus of rats: on-line monitoring of extracellular glutamate overflow. |
2001-02-08 |
2023-08-12 |
rat |
| T Saito, K Takahashi, N Nakagawa, T Hosokawa, M Kurasaki, O Yamanoshita, Y Yamamoto, H Sasaki, K Nagashima, H Fujit. Deficiencies of hippocampal Zn and ZnT3 accelerate brain aging of Rat. Biochemical and biophysical research communications. vol 279. issue 2. 2001-02-02. PMID:11118316. |
moreover, excessive presynaptic release of glutamate as well as glycine and expression of glial fibrillary acidic protein, a marker of neuronal cell injury, were observed in the hippocampus of aged samp10 compared to the control. |
2001-02-02 |
2023-08-12 |
mouse |
| J Zimmer, B W Kristensen, B Jakobsen, J Noraber. Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures. Amino acids. vol 19. issue 1. 2001-02-01. PMID:11026469. |
using organotypic slice cultures of hippocampus and cortex-striatum from newborn to 7 day old rats, we are currently studying the excitotoxic effects of kainic acid (ka), ampa and nmda and the neuroprotective effects of glutamate receptor blockers, like nbqx. |
2001-02-01 |
2023-08-12 |
rat |
| C G Parsons, W Danysz, G Quac. Memantine and the amino-alkyl-cyclohexane MRZ 2/579 are moderate affinity uncompetitive NMDA receptor antagonists--in vitro characterisation. Amino acids. vol 19. issue 1. 2001-02-01. PMID:11026484. |
mrz 2/579 protected cultured cortical neurones against glutamate toxicity with an ic50 of 2.16microm and was also effective in protecting hippocampal slices against hypoxia/hypoglycaemia-induced reduction of fepsp amplitude in ca1 with an ec50 of 7.01microm. |
2001-02-01 |
2023-08-12 |
Not clear |
| S G de Figueiredo, M E de Lima, M Nascimento Cordeiro, C R Diniz, D Patten, R F Halliwell, J Gilroy, M Richardso. Purification and amino acid sequence of a highly insecticidal toxin from the venom of the brazilian spider Phoneutria nigriventer which inhibits NMDA-evoked currents in rat hippocampal neurones. Toxicon : official journal of the International Society on Toxinology. vol 39. issue 2-3. 2001-01-26. PMID:10978749. |
preliminary electrophysiological studies carried out on whole-cell voltage-clamped rat hippocampal neurones indicated that tx4(5-5) (at 1 microm) reversibly inhibited the n-methyl-d-aspartate-subtype of ionotropic glutamate receptor, while having little or no effect on kainate-, alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid- or gamma-aminobutyric acid-activated currents. |
2001-01-26 |
2023-08-12 |
mouse |
| H J Reis, M V Gomez, E Kalapothakis, C R Diniz, M N Cordeiro, M A Prado, M A Romano-Silv. Inhibition of glutamate uptake by Tx3-4 is dependent on the redox state of cysteine residues. Neuroreport. vol 11. issue 10. 2001-01-25. PMID:10923668. |
among them is the toxin tx3-4, from the spider phoneutria nigriventer, which is able to inhibit glutamate uptake in rat hippocampal synaptosomes. |
2001-01-25 |
2023-08-12 |
rat |
| G L Wenk, C A Barne. Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain research. vol 885. issue 1. 2001-01-25. PMID:11121523. |
a thorough understanding of the mechanisms underlying changes in glutamate receptor function in discrete brain regions, using combined neurochemical and electrophysiological methods, may ultimately provide insight into the fundamental substrates of age-associated memory disorders related to hippocampal dysfunction. |
2001-01-25 |
2023-08-12 |
rat |
| Y Izumi, A R Zarrin, C F Zorumsk. Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098111. |
arachidonic acid rescues hippocampal long-term potentiation blocked by group i metabotropic glutamate receptor antagonists. |
2001-01-11 |
2023-08-12 |
rat |
| Y Izumi, A R Zarrin, C F Zorumsk. Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098111. |
among antagonists of group i metabotropic glutamate receptors, the mglur5-selective 6-methyl-2-(phenylethynyl)-pyridine inhibited long-term potentiation in the ca1 region of hippocampal slices from 30-day-old rats, whereas (rs)-1-aminoindan-1,5-dicarboxylic acid and cyclopropan[b]chromen-1a-carboxylic acid ethylester, which are more selective for mglur1, failed to inhibit long-term potentiation. |
2001-01-11 |
2023-08-12 |
rat |
| T Jehle, W A Lagrèze, E Blauth, R Knörle, P Schnierle, C H Lücking, T J Feuerstei. Gabapentin-lactam (8-aza-spiro[5,4]decan-9-on; GBP-L) inhibits oxygen glucose deprivation-induced [3H]glutmate release and is a neuroprotective agent in amodel of acute retinal ischemia. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 1. 2001-01-08. PMID:10935536. |
the modulation of the enhanced release of [3h]glutamate following ischemia-like conditions was studied in rat hippocampal slices using a superfusion system. |
2001-01-08 |
2023-08-12 |
rat |
| N B Saul'skaya, O L Pudovkina, A I Gorbachevskay. Increases in glutamate release in the nucleus accumbens in rats with lesions to the hippocampal formation during an emotional conditioned response. Neuroscience and behavioral physiology. vol 30. issue 4. 2001-01-04. PMID:10981943. |
intracerebral dialysis was used in living animals, along with high-performance liquid chromatography with electrochemical detection, to study glutamate release into the intercellular space of the nucleus accumbens during an emotional conditioned response in rats with lesions to the hippocampal glutamatergic input to this structure. |
2001-01-04 |
2023-08-12 |
rat |
| A S Rössler, H Schröder, R H Dodd, G Chapouthier, G Grecksc. Benzodiazepine receptor inverse agonist-induced kindling of rats alters learning and glutamate binding. Pharmacology, biochemistry, and behavior. vol 67. issue 1. 2001-01-04. PMID:11113497. |
on the other hand, hippocampal glutamate binding, has previously been shown to be modified by both seizures and learning. |
2001-01-04 |
2023-08-12 |
human |
| A S Rössler, H Schröder, R H Dodd, G Chapouthier, G Grecksc. Benzodiazepine receptor inverse agonist-induced kindling of rats alters learning and glutamate binding. Pharmacology, biochemistry, and behavior. vol 67. issue 1. 2001-01-04. PMID:11113497. |
l-[3h] glutamate binding to hippocampal membrane fractions of the fully kindled animals was significantly higher when compared with controls, whereas l-[3h] glutamate binding of not fully kindled subjects did not differ from that of controls. |
2001-01-04 |
2023-08-12 |
human |
| R Bernabeu, F R Shar. NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 12. 2001-01-04. PMID:11129783. |
nmda and ampa/kainate glutamate receptors modulate dentate neurogenesis and ca3 synapsin-i in normal and ischemic hippocampus. |
2001-01-04 |
2023-08-12 |
Not clear |
| R Bernabeu, F R Shar. NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 12. 2001-01-04. PMID:11129783. |
the effect of n-methyl-d-aspartate (nmda) and 2-(aminomethyl)phenylacetic acid/kainate (ampa/kainate) glutamate receptors on dentate cell proliferation and hippocampal synapsin-i induction was examined after global ischemia. |
2001-01-04 |
2023-08-12 |
Not clear |
| R Bernabeu, F R Shar. NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 12. 2001-01-04. PMID:11129783. |
it is proposed that decreased dentate glutamate receptor activation--produced by glutamate receptor antagonists in normal animals and by chronic ischemic hippocampal injury--may trigger dentate neurogenesis and synaptogenesis. |
2001-01-04 |
2023-08-12 |
Not clear |
| A J Heynen, E M Quinlan, D C Bae, M F Bea. Bidirectional, activity-dependent regulation of glutamate receptors in the adult hippocampus in vivo. Neuron. vol 28. issue 2. 2001-01-04. PMID:11144361. |
bidirectional, activity-dependent regulation of glutamate receptors in the adult hippocampus in vivo. |
2001-01-04 |
2023-08-12 |
Not clear |