| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chunxia Huang, John Man Tak Chu, Yan Liu, Vivian Suk Wai Kwong, Raymond Chuen Chung Chang, Gordon Tin Chun Won. Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682930. |
our findings indicate that sevoflurane-induced cognitive deterioration in 3 × tg mice, which was accompanied with the modulation of glutamate transporter, mapk signaling, and neuronal apoptosis in the cortical and hippocampal regions. |
2022-06-10 |
2023-08-14 |
mouse |
| Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiol. Disruption of Glutamate Homeostasis in the Brain of Rat Offspring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet. Nutrients. vol 14. issue 11. 2022-06-10. PMID:35683984. |
glutamate concentration was assessed in extracellular fluid samples collected from the medial prefrontal cortex and hippocampus of male and female offspring. |
2022-06-10 |
2023-08-14 |
rat |
| Siddhant Kumarapuram, Ansley J Kunnath, Anton Omelchenko, Nada N Boustany, Bonnie L Firestei. Glutamate Receptors Mediate Changes to Dendritic Mitochondria in Neurons Grown on Stiff Substrates. Annals of biomedical engineering. 2022-06-02. PMID:35652995. |
since mitochondria affect the shape of dendrites, in this study, we determined whether the stiffness of substrates on which rat hippocampal neurons are grown affects mitochondrial characteristics and if glutamate receptors mediate the effects of substrate stiffness. |
2022-06-02 |
2023-08-14 |
rat |
| Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
two fundamental characteristics comprise widespread changes in the relative expression of gaba and glutamate receptors and debilitation of hippocampal synaptic plasticity. |
2022-06-01 |
2023-08-13 |
mouse |
| Thomas M Sanderson, Liam T Ralph, Mascia Amici, Ai Na Ng, Bong-Kiun Kaang, Min Zhuo, Sang Jeong Kim, John Georgiou, Graham L Collingridg. Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD. Frontiers in synaptic neuroscience. vol 14. 2022-05-26. PMID:35615440. |
in area ca1 of the hippocampus, long-term depression (ltd) can be induced by activating group i metabotropic glutamate receptors (mglurs), with the selective agonist dhpg. |
2022-05-26 |
2023-08-13 |
Not clear |
| Jeong Hwan Oh, Youn Hee Choi, Taek-Jeong Na. Glycoproteins of Capsosiphon fulvescens modulate synaptic clustering of PSD95 and prevent social isolation-induced cognitive decline in aged male rats. The Journal of nutritional biochemistry. 2022-05-24. PMID:35609859. |
the oral administration of cf-hgp (15 mg/kg/day, 4 weeks) reversed the social isolation-induced decreases in phosphorylation of extracellular signal‑regulated protein kinase 1/2 (erk1/2), postsynaptic density protein 95 (psd95), and α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit 1 and increased expression of metabotropic glutamate receptor 5 in the synaptosome of the dorsal hippocampus. |
2022-05-24 |
2023-08-13 |
rat |
| Max Anstötz, Sun Kyong Lee, Gianmaria Maccaferr. Glutamate released by Cajal-Retzius cells impacts specific hippocampal circuits and behaviors. Cell reports. vol 39. issue 7. 2022-05-18. PMID:35584670. |
glutamate released by cajal-retzius cells impacts specific hippocampal circuits and behaviors. |
2022-05-18 |
2023-08-13 |
Not clear |
| Max Anstötz, Sun Kyong Lee, Gianmaria Maccaferr. Glutamate released by Cajal-Retzius cells impacts specific hippocampal circuits and behaviors. Cell reports. vol 39. issue 7. 2022-05-18. PMID:35584670. |
we conclude that glutamate synaptically released by cajal-retzius cells is critical for the regulation of hippocampal microcircuits and specific types of behaviors. |
2022-05-18 |
2023-08-13 |
Not clear |
| Ting-Yang Hsieh, Yi Chang, Su-Jane Wan. Piperine Provides Neuroprotection against Kainic Acid-Induced Neurotoxicity via Maintaining NGF Signalling Pathway. Molecules (Basel, Switzerland). vol 27. issue 9. 2022-05-14. PMID:35565989. |
our results show that ka exposure in rats caused seizure behaviour, intrinsic neuronal hyperactivity, glutamate elevation, hippocampal neuronal damage, and cognitive impairment. |
2022-05-14 |
2023-08-13 |
rat |
| Shafiqur Rahman, Ghallab Alotaib. Glutamate transporter activator LDN-212320 attenuates CFA-induced cognitive deficits and anxiety-like behavior in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555963. |
the astroglial glutamate transporter-1 (glt-1) in the hippocampus and anterior cingulate cortex (acc) is critically involved in acute and chronic nociceptive pain. |
2022-05-13 |
2023-08-13 |
mouse |
| Christina Acosta, Garrett Clemons, Cristiane Citadin, William Carr, Mariana Bertoudo, Yinchieh Wu, Huichao Lee, Hungwen Li. The pathological progression of repetitive and mild traumatic brain injury in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556696. |
using lc-ms, we measured excitatory neurotransmitters to suggest that glutamate was enhanced in the hippocampus 3-day post-rmtbi. |
2022-05-13 |
2023-08-13 |
mouse |
| Ruixue Yu, Wenqing Yang, Dongmei Qi, Lili Gong, Chao Li, Yunlun Li, Haiqiang Jian. Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats. RSC advances. vol 9. issue 40. 2022-05-06. PMID:35514525. |
oa could effectively restore tyrosine metabolism in the striatum and hypothalamus, glutamate metabolism in the hippocampus, striatum and temporal lobe, cholinergic metabolism in the striatum, and histidine metabolism in the hypothalamus due to its inhibition of inflammatory reactions, structural damage of the neuronal cells, and increase in sedative activity. |
2022-05-06 |
2023-08-13 |
rat |
| Maria Bove, Stefania Schiavone, Paolo Tucci, Vladyslav Sikora, Stefania Dimonte, Anna Laura Colia, Maria Grazia Morgese, Luigia Trabac. Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms. Progress in neuro-psychopharmacology & biological psychiatry. 2022-04-23. PMID:35460811. |
moreover, by using this mouse model, we performed neurochemical and biomolecular analyses, quantifying neurotransmitters belonging to excitatory-inhibitory pathways, such as glutamate, glutamine and gamma-aminobutyric acid (gaba), as well as immune activation biomarkers related to asd, such as cd11b and glial fibrillary acidic protein (gfap), in the hippocampus and amygdala. |
2022-04-23 |
2023-08-13 |
mouse |
| Maria Bove, Stefania Schiavone, Paolo Tucci, Vladyslav Sikora, Stefania Dimonte, Anna Laura Colia, Maria Grazia Morgese, Luigia Trabac. Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms. Progress in neuro-psychopharmacology & biological psychiatry. 2022-04-23. PMID:35460811. |
in addition, we found decreased bdnf and enhanced gfap hippocampal expression levels, accompanied by elevations in glutamate amount, as well as reduction in gaba content in amygdala and hippocampus. |
2022-04-23 |
2023-08-13 |
mouse |
| Camille S Wang, Natali L Chanaday, Lisa M Monteggia, Ege T Kavalal. Probing the segregation of evoked and spontaneous neurotransmission via photobleaching and recovery of a fluorescent glutamate sensor. eLife. vol 11. 2022-04-14. PMID:35420542. |
here, we used photobleaching properties of iglusnfr, a fluorescent probe that detects glutamate, to investigate the subsynaptic organization of evoked and spontaneous release in primary hippocampal cultures. |
2022-04-14 |
2023-08-13 |
Not clear |
| Alessandra Caruso, Laura Ricceri, Angela Caruso, Ferdinando Nicoletti, Alessandra Gaetano, Sergio Scaccianoc. Postweaning social isolation and autism-like phenotype: a biochemical and behavioral comparative analysis. Behavioural brain research. 2022-04-14. PMID:35421428. |
pwsi reduced hippocampal levels of type 2 metabotropic glutamate (mglu2) receptors, and glucocorticoid and mineralocorticoid receptors. |
2022-04-14 |
2023-08-13 |
mouse |
| Mengtan Cai, Weihong Li. The Function of NF-Kappa B During Epilepsy, a Potential Therapeutic Target. Frontiers in neuroscience. vol 16. 2022-04-01. PMID:35360161. |
it is upregulated in neurons, glial cells, and endothelial cells, due to neuronal loss, glial cell proliferation, blood-brain barrier dysfunction, and hippocampal sclerosis through the glutamate and γ-aminobutyric acid imbalance, ion concentration changes, and other mechanisms. |
2022-04-01 |
2023-08-13 |
Not clear |
| Xiuhua Mao, Dandan Cai, Wei Lo. Music alleviates pain perception in depression mouse models by promoting the release of glutamate in the hippocampus of mice to act on GRIK5. Nucleosides, nucleotides & nucleic acids. 2022-03-31. PMID:35357273. |
music alleviates pain perception in depression mouse models by promoting the release of glutamate in the hippocampus of mice to act on grik5. |
2022-03-31 |
2023-08-13 |
mouse |
| Jia-Xing Liu, Jia-Han Li, Chen-Hui DU, Yan Ya. [Metabonomic study of biochemical changes in serum of PCPA-induced insomnia rats after treatment with Suanzaoren Decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 6. 2022-03-29. PMID:35347962. |
then pathological changes of the liver and brain were observed and biochemical indexes such as 5-hydroxytryptamine(5-ht), dopamine(da), glutamate(glu), γ-aminobutyric acid(gaba), and norepinephrine(ne) in the hippocampus and prostaglandin d2(pgd2), tumor necrosis factor-α(tnf-α), interleukin-1β(il-1β), and il-6 in the serum of rats were detected. |
2022-03-29 |
2023-08-13 |
rat |
| Ana Elena Teleuca, Giovanni Sebastiano Alemà, Paola Casolini, Ilaria Barberis, Francesco Ciabattoni, Rosamaria Orlando, Luisa Di Menna, Luisa Iacovelli, Maria Rosaria Scioli, Ferdinando Nicoletti, Anna Rita Zuen. Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice. Life (Basel, Switzerland). vol 12. issue 3. 2022-03-25. PMID:35330215. |
using an in vivo method for the assessment of polyphosphoinositide (pi) hydrolysis, we examine whether spatial learning and memory extinction cause changes in mglu5 metabotropic glutamate receptor signaling in the hippocampus and prefrontal cortex. |
2022-03-25 |
2023-08-13 |
mouse |