| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brigitte Potier, Louison Lallemant, Sandrine Parrot, Aline Huguet-Lachon, Geneviève Gourdon, Patrick Dutar, Mário Gomes-Pereir. DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35054778. |
we confirmed reduced glutamate uptake in the dmsxl hippocampus. |
2022-01-21 |
2023-08-13 |
mouse |
| Brigitte Potier, Louison Lallemant, Sandrine Parrot, Aline Huguet-Lachon, Geneviève Gourdon, Patrick Dutar, Mário Gomes-Pereir. DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35054778. |
patch clamp recordings in hippocampal slices revealed increased amplitude of tonic glutamate currents in dmsxl ca1 pyramidal neurons and dg granule cells, likely mediated by higher levels of ambient glutamate. |
2022-01-21 |
2023-08-13 |
mouse |
| E A Matthews, W Sun, S M McMahon, M Doengi, L Halka, S Anders, J A Müller, P Steinlein, N S Vana, G van Dyk, J Pitsch, A J Becker, A Pfeifer, E T Kavalali, A Lamprecht, C Henneberger, V Stein, S Schoch, D Dietric. Optical Analysis of Glutamate Spread in the Neuropil. Cerebral cortex (New York, N.Y. : 1991). 2022-01-21. PMID:35059716. |
here, we show that quantal glutamate release from individual hippocampal synapses activates extracellular iglusnfr molecules at a distance of >1.5 μm. |
2022-01-21 |
2023-08-13 |
Not clear |
| Qiong Fang, Jing Liu, Lang Chen, Qiaobin Chen, Yan Wang, Zuanfang Li, Wei Fu, Ying Li. Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis. Metabolic brain disease. 2022-01-20. PMID:35048325. |
antenatal taurine supplementation increased the ratios of n-acetylaspartate (naa) /creatine (cr) and glutamate (glu) /cr of the hippocampus in the iugr immature rats, but reduced the ratios of choline (cho) /cr and myoinositol (mi) /cr. |
2022-01-20 |
2023-08-13 |
rat |
| Theresa S Rimmele, Shaomin Li, Jens Velde Andersen, Emil W Westi, Alexander Rotenberg, Jianlin Wang, Blanca Irene Aldana, Dennis J Selkoe, Chiye J Aoki, Chris G Dulla, Paul Allen Rosenber. Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus. Frontiers in cellular neuroscience. vol 15. 2022-01-17. PMID:35035352. |
neuronal loss of the glutamate transporter glt-1 promotes excitotoxic injury in the hippocampus. |
2022-01-17 |
2023-08-13 |
mouse |
| Peng Ren, Bin Xiao, Lin-Ping Wang, Ying-Shun Li, Hua Jin, Qing-Hua Ji. Nitric oxide impairs spatial learning and memory in a rat model of Alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. Behavioural brain research. 2022-01-16. PMID:35033612. |
nitric oxide impairs spatial learning and memory in a rat model of alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. |
2022-01-16 |
2023-08-13 |
rat |
| Peng Ren, Bin Xiao, Lin-Ping Wang, Ying-Shun Li, Hua Jin, Qing-Hua Ji. Nitric oxide impairs spatial learning and memory in a rat model of Alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning. Behavioural brain research. 2022-01-16. PMID:35033612. |
however, whether no in the hippocampal dentate gyrus (dg) is involved in the spatial learning and memory impairments of ad by affecting the glutamate (glu) response during these processes is not well-understood. |
2022-01-16 |
2023-08-13 |
rat |
| Tania López-Hernández, Koh-Ichiro Takenaka, Yasunori Mori, Pornparn Kongpracha, Shushi Nagamori, Volker Haucke, Shigeo Takamor. Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses. eLife. vol 11. 2022-01-11. PMID:35014951. |
we report on the comprehensive survey of six major sv proteins to show that sv endocytosis in mouse hippocampal neurons at physiological temperature occurs independent of clathrin while the endocytic retrieval of a subset of sv proteins including the vesicular transporters for glutamate and gaba depend on sorting by the clathrin adaptor ap-2. |
2022-01-11 |
2023-08-13 |
mouse |
| Rakshathi Basavaraju, Jia Guo, Scott A Small, Jeffrey A Lieberman, Ragy R Girgis, Frank A Provenzan. Hippocampal Glutamate and Positive Symptom Severity in Clinical High Risk for Psychosis. JAMA psychiatry. 2021-12-29. PMID:34964821. |
hippocampal glutamate and positive symptom severity in clinical high risk for psychosis. |
2021-12-29 |
2023-08-13 |
Not clear |
| Sarah Woelfle, Tobias M Boecker. Layer-Specific Vesicular Glutamate Transporter 1 Immunofluorescence Levels Delineate All Layers of the Human Hippocampus Including the Frontiers in cellular neuroscience. vol 15. 2021-12-27. PMID:34955756. |
layer-specific vesicular glutamate transporter 1 immunofluorescence levels delineate all layers of the human hippocampus including the the hippocampal formation consists of the ammon's horn ( |
2021-12-27 |
2023-08-13 |
human |
| Yuki Kambe, Thu Nguyen Thi, Kohei Hashiguchi, Yoshimune Sameshima, Akira Yamashita, Takashi Kurihara, Atsuro Miyat. The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice. Journal of pharmacological sciences. vol 148. issue 1. 2021-12-20. PMID:34924114. |
the dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice. |
2021-12-20 |
2023-08-13 |
mouse |
| Yuki Kambe, Thu Nguyen Thi, Kohei Hashiguchi, Yoshimune Sameshima, Akira Yamashita, Takashi Kurihara, Atsuro Miyat. The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice. Journal of pharmacological sciences. vol 148. issue 1. 2021-12-20. PMID:34924114. |
these results indicate that ptg in the dorsal hippocampal astrocytes may contribute to working and short-term memories by maintaining the expression of glutamate receptor subunits. |
2021-12-20 |
2023-08-13 |
mouse |
| Honoka Fujimori, Takuya Ohba, Masashi Mikami, Shinsuke Nakamura, Kenichi Ito, Hiroyuki Kojima, Tatsuji Takahashi, Arunasiri Iddamalgoda, Masamitsu Shimazawa, Hideaki Har. The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment. Journal of pharmacological sciences. vol 148. issue 1. 2021-12-20. PMID:34924122. |
further, murine hippocampal cells (ht22) were damaged by glutamate, an oxidative stress inducer. |
2021-12-20 |
2023-08-13 |
mouse |
| Seungjae Zhang, Myunghyun Cheon, Hoyong Park, Taejoon Kim, ChiHye Chun. Interaction between glucocorticoid receptors and FKBP5 in regulating neurotransmission of the hippocampus. Neuroscience. 2021-12-19. PMID:34923037. |
in the hippocampus, gr activation alters the release probability in inhibitory synapses as well as the postsynaptic contribution of glutamate receptors in excitatory synapses; however, no such alterations were induced in the absence of fkbp5. |
2021-12-19 |
2023-08-13 |
mouse |
| Jason H Y Yeung, Joshua L Walby, Thulani H Palpagama, Clinton Turner, Henry J Waldvogel, Richard L M Faull, Andrea Kwakowsk. Glutamatergic receptor expression changes in the Alzheimer's disease hippocampus and entorhinal cortex. Brain pathology (Zurich, Switzerland). vol 31. issue 6. 2021-12-11. PMID:34269494. |
free-floating immunohistochemistry and confocal laser scanning microscopy were used to quantify the density of glutamate receptor subunits glua2, glun1, and glun2a in specific cell layers of the hippocampal sub-regions, subiculum, entorhinal cortex, and superior temporal gyrus. |
2021-12-11 |
2023-08-13 |
human |
| Cesar Arturo Pinzón-Parra, Heriberto Coatl-Cuaya, Alfonso Díaz, Jorge Guevara, Antonio Rodríguez-Moreno, Gonzalo Flore. Long-term effect of neonatal antagonism of ionotropic glutamate receptors on dendritic spines and cognitive function in rats. Journal of chemical neuroanatomy. vol 119. 2021-12-11. PMID:34839003. |
glutamate is the most abundant excitatory neurotransmitter in the hippocampus where mediates its actions by activating glutamate receptors. |
2021-12-11 |
2023-08-13 |
rat |
| Cesar Arturo Pinzón-Parra, Heriberto Coatl-Cuaya, Alfonso Díaz, Jorge Guevara, Antonio Rodríguez-Moreno, Gonzalo Flore. Long-term effect of neonatal antagonism of ionotropic glutamate receptors on dendritic spines and cognitive function in rats. Journal of chemical neuroanatomy. vol 119. 2021-12-11. PMID:34839003. |
we found that ionotropic glutamate receptor function blockade at neonatal age causes a reduction in short and long-term memory in adulthood and a reduction in the expression of synaptophysin and actin protein levels in the hippocampus regions studied. |
2021-12-11 |
2023-08-13 |
rat |
| Hiroko Ikeda, Shogo Yamamoto, Junzo Kame. Increase in brain l-lactate enhances fear memory in diabetic mice: Involvement of glutamate neurons. Brain research. vol 1767. 2021-12-09. PMID:34129854. |
the glucose transporter (glut) 1 was significantly increased both in the amygdala and in the hippocampus. |
2021-12-09 |
2023-08-13 |
mouse |
| Hiroko Ikeda, Shogo Yamamoto, Junzo Kame. Increase in brain l-lactate enhances fear memory in diabetic mice: Involvement of glutamate neurons. Brain research. vol 1767. 2021-12-09. PMID:34129854. |
injection of l-lactate significantly increased glutamate levels in the amygdala and hippocampus. |
2021-12-09 |
2023-08-13 |
mouse |
| Katarzyna Stachowicz, Bartosz Bobula, Magdalena Kusek, Tomasz Lenda, Krzysztof Tokarsk. Evidence for the interaction of COX-2 with mGluR5 in the regulation of EAAT1 and EAAT3 protein levels in the mouse hippocampus. The influence of oxidative stress mechanisms. Brain research. vol 1771. 2021-12-09. PMID:34529964. |
since we found that inhibition of cyclooxygenase-2 (cox-2) with concomitant application of a metabotropic glutamate receptor subtype 5 (mglur5) antagonist (mtep) down-regulates mglur7 in the hippocampus (hc) and changes behavior of mice, our team decided to investigate the mechanism responsible for the observed changes. |
2021-12-09 |
2023-08-13 |
mouse |