| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ankita Bhardwaj, Rishi Bhardwaj, Shweta Sharma, Suresh Kumar Sharma, Devinder Kumar Dhawan, Tanzeer Kau. AMPA induced cognitive impairment in rats: Establishing the role of endoplasmic reticulum stress inhibitor, 4-PBA. Journal of neuroscience research. vol 99. issue 10. 2021-11-18. PMID:34197000. |
the levels of neurotransmitters such as dopamine, homo vanillic acid (hva), norepinephrine, and serotonin were reduced accompanied by reduced expression of glur1 and glur4 (glutamate receptor) as well as loss of neurons in different layers of hippocampus. |
2021-11-18 |
2023-08-13 |
rat |
| Wei-Wei Gu, Xin Cui, Li-Zhe Liu, Min Zhang, Xiao-Hui Xian, Wen-Bin L. Sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the CA1 region of hippocampus of global brain ischemic rats. Amino acids. vol 53. issue 11. 2021-11-16. PMID:34716803. |
sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the ca1 region of hippocampus of global brain ischemic rats. |
2021-11-16 |
2023-08-13 |
rat |
| Wei Sun, Xiaoliang Li, Dongxin Tang, Yuanhua Wu, Lei A. Subacute melamine exposure disrupts task-based hippocampal information flow via inhibiting the subunits 2 and 3 of AMPA glutamate receptors expression. Human & experimental toxicology. vol 40. issue 6. 2021-11-15. PMID:33243008. |
subacute melamine exposure disrupts task-based hippocampal information flow via inhibiting the subunits 2 and 3 of ampa glutamate receptors expression. |
2021-11-15 |
2023-08-13 |
rat |
| Homood Alharbi, Mohammad Ahmad, Zhenhua Tian, Ruixue Yu, Yun Lun L. Therapeutic value of the metabolomic active neurotransmitter isorhynchophylline in the treatment of spontaneously hypertensive rats by regulating neurotransmitters. Translational neuroscience. vol 12. issue 1. 2021-11-12. PMID:34760298. |
so, isorhynchophylline has been proved to have potential therapeutic value to treat hypertension via tyrosine and glutamate metabolism in the hippocampus. |
2021-11-12 |
2023-08-13 |
human |
| Mizuki Uchida, Yukihiro Noda, Sho Hasegawa, Hirotake Hida, Masayuki Taniguchi, Akihiro Mouri, Akira Yoshimi, Toshitaka Nabeshima, Kiyofumi Yamada, Tomomi Aida, Kohichi Tanaka, Norio Ozak. Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochemistry international. vol 150. 2021-11-11. PMID:34481039. |
at 8 weeks of age, they showed impairments in cognitive or emotional behaviors; dysfunction of glutamatergic neurotransmission (increased expressions of glast, glt-1, or gfap protein, and decreased ability of glutamate release) in the cortex or hippocampus; morphological changes (decreased cell size in the cortex and thickness of the pyramidal neuronal layer of the ca1 area in the hippocampus). |
2021-11-11 |
2023-08-13 |
mouse |
| Selda Özakman, M Zafer Gören, Asiye Nurten, Nurdan Tekin, Rivaze Kalaycı, Nurhan Engina. Effects of tamoxifen and glutamate and glutamine levels in brain regions in repeated sleep deprivation-induced mania model in mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 4. 2021-11-05. PMID:33104849. |
glutamate and glutamine levels were measured in the frontal cortex and hippocampus. |
2021-11-05 |
2023-08-13 |
mouse |
| Selda Özakman, M Zafer Gören, Asiye Nurten, Nurdan Tekin, Rivaze Kalaycı, Nurhan Engina. Effects of tamoxifen and glutamate and glutamine levels in brain regions in repeated sleep deprivation-induced mania model in mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 4. 2021-11-05. PMID:33104849. |
glutamate and glutamine levels and glutamate/glutamine ratio in the frontal cortex and hippocampus were unaffected. |
2021-11-05 |
2023-08-13 |
mouse |
| Serena Boccella, Francesca Guida, Monica Iannotta, Fabio Arturo Iannotti, Rosmara Infantino, Flavia Ricciardi, Claudia Cristiano, Rosa Maria Vitale, Pietro Amodeo, Ida Marabese, Carmela Belardo, Vito de Novellis, Salvatore Paino, Enza Palazzo, Antonio Calignano, Vincenzo Di Marzo, Sabatino Maione, Livio Luong. 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33557888. |
treatment for 14 days with pea-oxa after the onset of the symptoms associated with neuropathic pain resulted in the following effects: (i) allodynia was decreased; (ii) affective/cognitive impairment associated with sni (depression, spatial, and working memories) was counteracted; (iii) long-term potentiation in vivo in the lateral entorhinal cortex-dentate gyrus (perforant pathway, lpp) was ameliorated, (iv) hippocampal glutamate, gaba, histamine, norepinephrine and dopamine level alterations after peripheral nerve injury were reversed, (v) expression level of the th positive neurons in the locus coeruleus were normalized. |
2021-11-04 |
2023-08-13 |
mouse |
| Alessandro Piva, Lucia Caffino, Francesca Mottarlini, Nicholas Pintori, Fernando Castillo Díaz, Fabio Fumagalli, Cristiano Chiamuler. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus. Molecular neurobiology. vol 58. issue 7. 2021-11-03. PMID:33723767. |
metaplastic effects of ketamine and mk-801 on glutamate receptors expression in rat medial prefrontal cortex and hippocampus. |
2021-11-03 |
2023-08-13 |
rat |
| Alessandro Piva, Lucia Caffino, Francesca Mottarlini, Nicholas Pintori, Fernando Castillo Díaz, Fabio Fumagalli, Cristiano Chiamuler. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus. Molecular neurobiology. vol 58. issue 7. 2021-11-03. PMID:33723767. |
differently from mpfc, in hipp, both substances reduced or caused no changes of glutamate receptors and scaffolding proteins expression. |
2021-11-03 |
2023-08-13 |
rat |
| Chen Wang, Qi Yu, Dong Li, Na Sun, Yan Huang, Yong-Xiang Zhang, Wen-Xia Zho. Reduced D-Serine Release May Contribute to Impairment of Long-Term Potentiation by Corticosterone in the Perforant Path-Dentate Gyrus. Neurochemical research. vol 46. issue 9. 2021-11-03. PMID:34146194. |
corticosterone increased the glutamate level in hippocampal tissues, neither nmda receptors antagonist nor its subtype antagonists alleviated impairment of ltp, while enhancing the function of nmda receptors by d-serine did alleviate impairment of ltp by corticosterone, suggesting that hypofunction of nmda receptors might be one of the main reasons for impairment of ltp by corticosterone. |
2021-11-03 |
2023-08-13 |
mouse |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
hippocampal neuroanatomy in first episode psychosis: a putative role for glutamate and serotonin receptors. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
hippocampal atrophy is a well-established feature of schizophrenia, with select subfields hypothesized as particularly vulnerable due to variation in glutamate receptor densities. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
we investigated hippocampal anomalies in first-episode psychosis (fep) in relation to receptor distributions by leveraging 4 sources of data: (1) ultra high-field (7-tesla) structural neuroimaging, and (2) proton magnetic resonance spectroscopy (1h-mrs) of glutamate from 27 healthy and 41 fep subjects, (3) gene expression data from the allen human brain atlas and (4) atlases of the serotonin receptor system. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
we used gene expression data to correlate serotonin and glutamate receptor genes across the hippocampus. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
we demonstrate a putative glutamate-driven hippocampal variability in fep through a serotonin receptor-density gated mechanism, thus outlining a mechanistic interplay between serotonin and glutamate in determining the hippocampal morphology in schizophrenia. |
2021-11-01 |
2023-08-13 |
human |
| Negin Saeedi, Mahgol Darvishmolla, Zohreh Tavassoli, Shima Davoudi, Soomaayeh Heysieattalab, Narges Hosseinmardi, Mahyar Janahmadi, Gila Behzad. The role of hippocampal glial glutamate transporter (GLT-1) in morphine-induced behavioral responses. Brain and behavior. vol 11. issue 9. 2021-11-01. PMID:34363739. |
the role of hippocampal glial glutamate transporter (glt-1) in morphine-induced behavioral responses. |
2021-11-01 |
2023-08-13 |
rat |
| Negin Saeedi, Mahgol Darvishmolla, Zohreh Tavassoli, Shima Davoudi, Soomaayeh Heysieattalab, Narges Hosseinmardi, Mahyar Janahmadi, Gila Behzad. The role of hippocampal glial glutamate transporter (GLT-1) in morphine-induced behavioral responses. Brain and behavior. vol 11. issue 9. 2021-11-01. PMID:34363739. |
in this study, we evaluated the role of hippocampal glial glutamate transporter (glt-1) in morphine dependence. |
2021-11-01 |
2023-08-13 |
rat |
| Negin Saeedi, Mahgol Darvishmolla, Zohreh Tavassoli, Shima Davoudi, Soomaayeh Heysieattalab, Narges Hosseinmardi, Mahyar Janahmadi, Gila Behzad. The role of hippocampal glial glutamate transporter (GLT-1) in morphine-induced behavioral responses. Brain and behavior. vol 11. issue 9. 2021-11-01. PMID:34363739. |
therefore, its activation may reduce morphine side effects by reducing hippocampal glutamate. |
2021-11-01 |
2023-08-13 |
rat |
| Humberto Martínez-Orozco, Luis A Reyes-Castro, Consuelo Lomas-Soria, Cuauhtémoc Sandoval-Salazar, Joel Ramírez-Emiliano, Sofía Díaz-Cintra, Silvia Solís-Orti. High-fat and combined high-fat-high-fructose diets impair episodic-like memory and decrease glutamate and glutamine in the hippocampus of adult mice. Nutritional neuroscience. 2021-11-01. PMID:34719357. |
high-fat and combined high-fat-high-fructose diets impair episodic-like memory and decrease glutamate and glutamine in the hippocampus of adult mice. |
2021-11-01 |
2023-08-13 |
mouse |