| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Margarida V Caldeira, Michele Curcio, Graciano Leal, Ivan L Salazar, Miranda Mele, Ana Rita A Santos, Carlos V Melo, Paulo Pereira, Lorella M T Canzoniero, Carlos B Duart. Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons. Biochimica et biophysica acta. vol 1832. issue 1. 2013-03-04. PMID:23069389. |
we found that excitotoxic stimulation with glutamate rapidly decreases atp levels and the proteasome activity, and induces the disassembly of the 26s proteasome in cultured rat hippocampal neurons. |
2013-03-04 |
2023-08-12 |
rat |
| Margarida V Caldeira, Michele Curcio, Graciano Leal, Ivan L Salazar, Miranda Mele, Ana Rita A Santos, Carlos V Melo, Paulo Pereira, Lorella M T Canzoniero, Carlos B Duart. Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons. Biochimica et biophysica acta. vol 1832. issue 1. 2013-03-04. PMID:23069389. |
glutamate stimulation decreased the total deubiquitinase activity in hippocampal neurons, but was without effect on the activity of uch-l1, showing that not all deubiquitinases are affected. |
2013-03-04 |
2023-08-12 |
rat |
| Jesús Q Beltrán, Rafael Gutiérre. Co-release of glutamate and GABA from single, identified mossy fibre giant boutons. The Journal of physiology. vol 590. issue 19. 2013-02-26. PMID:22711957. |
electrophysiological recordings on hippocampal slices obtained during this period have shown that stimulation of the mossy fibres (mfs) provokes simultaneous monosynaptic gaba(a) and glutamate receptor-mediated responses in their target cells,which have the pharmacological and physiological characteristics of mf neurotransmission. |
2013-02-26 |
2023-08-12 |
rat |
| Filipe C Matheus, Aderbal S Aguiar, Adalberto A Castro, Jardel G Villarinho, Juliano Ferreira, Cláudia P Figueiredo, Roger Walz, Adair R S Santos, Carla I Tasca, Rui D S Predige. Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Behavioural brain research. vol 235. issue 2. 2013-02-25. PMID:22921927. |
these behavioral benefits of exogenous agmatine administration were accompanied by a protection against the mptp-induced decrease of hippocampal glutamate uptake and loss of dopaminergic neurons in the substantia nigra pars compacta of aging mice, without altering brain monoamine oxidase b (mao-b) activity. |
2013-02-25 |
2023-08-12 |
mouse |
| Kioko Guzmán-Ramos, Perla Moreno-Castilla, Monica Castro-Cruz, James L McGaugh, Hilda Martínez-Coria, Frank M LaFerla, Federico Bermúdez-Ratton. Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 10. 2013-02-22. PMID:22984283. |
the aim of this study was to assess, by in vivo microdialysis, cortical and hippocampal dopamine, norepinephrine, and glutamate release during the acquisition of object recognition memory (orm) in 5- and 10-mo-old triple-transgenic alzheimer's disease mice (3xtg-ad) and to relate the extracellular changes to 24-h memory performance. |
2013-02-22 |
2023-08-12 |
mouse |
| Wan-Hui Lin, Hua-Pin Huang, Ming-Xing Lin, Sheng-Gen Che. [The effect of high frequency stimulation of epileptic foci on the release of glutamate and gamma-aminobutyric acid in hippocampus of the kainic acid-kindled rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 27. issue 1. 2013-02-21. PMID:21560351. |
[the effect of high frequency stimulation of epileptic foci on the release of glutamate and gamma-aminobutyric acid in hippocampus of the kainic acid-kindled rats]. |
2013-02-21 |
2023-08-12 |
rat |
| Wan-Hui Lin, Hua-Pin Huang, Ming-Xing Lin, Sheng-Gen Che. [The effect of high frequency stimulation of epileptic foci on the release of glutamate and gamma-aminobutyric acid in hippocampus of the kainic acid-kindled rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 27. issue 1. 2013-02-21. PMID:21560351. |
to observe the dynamics of hippocampal release of glutamate (glu) and gamma-aminobutyric acid (gaba) in epilepsy (tle) after administration with high frequency stimulation (hfs). |
2013-02-21 |
2023-08-12 |
rat |
| Myriam Kervern, Arnaud Angeli, Olivier Nicole, Frédéric Léveillé, Bénédicte Parent, Vincent Villette, Alain Buisson, Patrick Duta. Selective impairment of some forms of synaptic plasticity by oligomeric amyloid-β peptide in the mouse hippocampus: implication of extrasynaptic NMDA receptors. Journal of Alzheimer's disease : JAD. vol 32. issue 1. 2013-02-20. PMID:22785392. |
using a combination of electrophysiological and biochemical techniques in mouse hippocampal slices, we show here that aβo drastically affects synaptic plasticities induced by high stimulation frequencies through the involvement of extrasynaptic glutamate receptors. |
2013-02-20 |
2023-08-12 |
mouse |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. |
2013-02-19 |
2023-08-12 |
rat |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
we report here that prs rats showed a selective impairment of depolarization- or kainate-stimulated glutamate and [(3)h]d-aspartate release in the ventral hippocampus, a region encoding memories related to stress and emotions. |
2013-02-19 |
2023-08-12 |
rat |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
abnormalities of glutamate release were associated with large reductions in the levels of synaptic vesicle-related proteins, such as vamp (synaptobrevin), syntaxin-1, synaptophysin, synapsin ia/b and iia, munc-18, and rab3a in the ventral hippocampus of prs rats. |
2013-02-19 |
2023-08-12 |
rat |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
anxiety-like behavior in male prs (and control) rats was inversely related to the extent of depolarization-evoked glutamate release in the ventral hippocampus. |
2013-02-19 |
2023-08-12 |
rat |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
a causal relationship between anxiety-like behavior and reduction in glutamate release was demonstrated using a mixture of the mglu2/3 receptor antagonist, ly341495, and the gaba(b) receptor antagonist, cgp52432, which was shown to amplify depolarization-evoked [(3)h]d-aspartate release in the ventral hippocampus. |
2013-02-19 |
2023-08-12 |
rat |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
these findings indicate that an impairment of glutamate release in the ventral hippocampus is a key component of the neuroplastic program induced by prs, and that strategies aimed at enhancing glutamate release in the ventral hippocampus correct the "anxious phenotype" caused by early life stress. |
2013-02-19 |
2023-08-12 |
rat |
| Ai-Lin Du, Shuang Li, Hong-Bo Jiang, Wen-Qiang Li, Wei Hiao, Rui-Ling Zhan. [Effect of butylphthalide on levels of glutamate and expression of NR2B in the hippocampus of rats with alcohol addiction]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 28. issue 1. 2013-02-15. PMID:22493886. |
[effect of butylphthalide on levels of glutamate and expression of nr2b in the hippocampus of rats with alcohol addiction]. |
2013-02-15 |
2023-08-12 |
rat |
| Marcos Brandão Contó, Marco Antonio Campana Venditt. In vitro studies of the influence of glutamatergic agonists on the Na+,K(+)-ATPase and K(+)-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats. Journal of negative results in biomedicine. vol 11. 2013-02-15. PMID:22574873. |
in the present study, we investigated whether glutamatergic stimulation by the glutamatergic agonists glutamate, α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (ampa), kainate and n-methyl-d-aspartate (nmda) modulates the na(+),k(+)-atpase and the k(+)-p-nitrophenylphosphatase activities in the crude synaptosomal fraction of the hippocampus and the frontal cortex of rats. |
2013-02-15 |
2023-08-12 |
rat |
| b' Nino Nebieridze, Xiao-Lei Zhang, Tamar Chachua, Libor Vel\\xc3\\xad\\xc5\\xa1ek, Patric K Stanton, Jana Vel\\xc3\\xad\\xc5\\xa1kov\\xc3\\xa. \\xce\\xb2-Estradiol unmasks metabotropic receptor-mediated metaplasticity of NMDA receptor transmission in the female rat dentate gyrus. Psychoneuroendocrinology. vol 37. issue 11. 2013-02-12. PMID:22541715.' |
the gatekeeping function of the dentate gyrus to filter incoming activity into the hippocampus is modulated by estradiol in a frequency-dependent manner and involves activation of metabotropic glutamate receptors (mglur). |
2013-02-12 |
2023-08-12 |
rat |
| Hui Jiang, Shunlian Tian, Yan Zeng, Jing Sh. Nerve growth factor inhibits Gd(3+)-sensitive calcium influx and reduces chemical anoxic neuronal death. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 28. issue 4. 2013-02-11. PMID:18704295. |
when combination of 20 micromol/l mk-801 (glutamate receptor antagonist), 40 micromol/l cnqx (ampa receptor antagonist) and 5 micromol/l nimodipine (voltage-gated calcium channel antagonist) (hereafter denoted as mcn) were administrated to hippocampal cultures, levels of [ca(2+)](i) and cell death rate induced by kcn were partially reduced by 35.9% and 47.5% respectively. |
2013-02-11 |
2023-08-12 |
rat |
| Z L Jiang, Y R Chen, C Zhou, J S Shi, S M Dua. [Glutamate-related mechanism of ginsenosides against anoxic-ischemic brain damage]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 2. 2013-02-11. PMID:21171388. |
to observe the antagonist effect of ginsenosides upon excitatory neurotoxicity of glutamate in rat hippocampal slices, and to observe the inhibitory and facilitated effects of ginsenosides upon glutamate release from cultured mice cortical neurons and upon glutamate uptake by cultured astrocytes, respectively, during simulated ischemia, in order to elucidate whether the protective effect of ginsenosides against anoxic-ischemic brain damage is related to reducing the excitatory neurotoxicity of glutamate. |
2013-02-11 |
2023-08-12 |
mouse |
| Walailuk Kerdsan, Samur Thanoi, Sutisa Nudmamud-Thano. Changes in the neuronal glutamate transporter EAAT3 in rat brain after exposure to methamphetamine. Basic & clinical pharmacology & toxicology. vol 111. issue 4. 2013-02-08. PMID:22540959. |
methamphetamine (meth), an addictive psychostimulant, can induce glutamate release in several brain areas such as cerebral cortex, hippocampus and striatum. |
2013-02-08 |
2023-08-12 |
rat |