| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| János Brunner, Jeanne Ster, Susan Van-Weert, Tibor Andrási, Máté Neubrandt, Corrado Corti, Mauro Corsi, Francesco Ferraguti, Urs Gerber, János Szabadic. Selective silencing of individual dendritic branches by an mGlu2-activated potassium conductance in dentate gyrus granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 17. 2013-06-25. PMID:23616537. |
group ii metabotropic glutamate receptors (mglu-iis) modulate hippocampal information processing through several presynaptic actions. |
2013-06-25 |
2023-08-12 |
mouse |
| Alison X Xie, Min-Yu Sun, Thomas Murphy, Kelli Lauderdale, Elizabeth Tiglao, Todd A Fiacc. Bidirectional scaling of astrocytic metabotropic glutamate receptor signaling following long-term changes in neuronal firing rates. PloS one. vol 7. issue 11. 2013-06-20. PMID:23166735. |
here we provide evidence for bidirectional scaling of astrocytic group i metabotropic glutamate receptor signaling in acute mouse hippocampal slices following long-term changes in neuronal firing rates. |
2013-06-20 |
2023-08-12 |
mouse |
| J Grohm, S-W Kim, U Mamrak, S Tobaben, A Cassidy-Stone, J Nunnari, N Plesnila, C Culmse. Inhibition of Drp1 provides neuroprotection in vitro and in vivo. Cell death and differentiation. vol 19. issue 9. 2013-06-19. PMID:22388349. |
drp1 sirna and small molecule inhibitors of drp1 prevented mitochondrial fission, loss of mitochondrial membrane potential (mmp), and cell death induced by glutamate or tbid overexpression in immortalized hippocampal ht-22 neuronal cells. |
2013-06-19 |
2023-08-12 |
mouse |
| Iswar Baitharu, Satya Narayan Deep, Vishal Jain, Dipti Prasad, G Ilavazhaga. Inhibition of glucocorticoid receptors ameliorates hypobaric hypoxia induced memory impairment in rat. Behavioural brain research. vol 240. 2013-06-17. PMID:23159706. |
the underlying mechanisms of hh induced memory impairment have been attributed to prolonged elevated corticosterone level in hippocampus leading to augmented glutamate excitotoxicity, oxidative stress, alteration of neurotransmitter level or their receptors and calcium mediated signaling. |
2013-06-17 |
2023-08-12 |
rat |
| Xin Li Xiao, Dong Liang Ma, Jing Wu, Feng-Ru Tan. Metabotropic glutamate receptor 5 (mGluR5) regulates proliferation and differentiation of neuronal progenitors in the developmental hippocampus. Brain research. vol 1493. 2013-06-13. PMID:23165119. |
metabotropic glutamate receptor 5 (mglur5) regulates proliferation and differentiation of neuronal progenitors in the developmental hippocampus. |
2013-06-13 |
2023-08-12 |
mouse |
| Simo S Oja, Pirjo Saransaar. Regulation of taurine release in the hippocampus of developing and adult mice. Advances in experimental medicine and biology. vol 775. 2013-06-12. PMID:23392930. |
the taurine released may counteract any excitotoxic effects of glutamate, particularly in the developing hippocampus. |
2013-06-12 |
2023-08-12 |
mouse |
| Chang Hui Shen, Eugene Lempert, Isma Butt, Lorenz S Neuwirth, Xin Yan, Abdeslem El Idriss. Changes in gene expression at inhibitory synapses in response to taurine treatment. Advances in experimental medicine and biology. vol 775. 2013-06-12. PMID:23392935. |
these changes include increased levels of the neurotransmitters gaba and glutamate, increased expression of both isoforms of gad and the neuropeptide somatostatin, decreased hippocampal expression of the beta (β) 2/3 subunits of the gaba(a) receptor, an increase in the number of somatostatin-positive neurons, and an increase in the amplitude and duration of population spikes recorded from ca1 in response to schaefer collateral stimulation and enhanced paired pulse facilitation in the hippocampus. |
2013-06-12 |
2023-08-12 |
mouse |
| Devon C Crawford, Xiaoping Jiang, Amanda Taylor, Krista L Moulder, Steven Menneric. Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals. PloS one. vol 7. issue 12. 2013-06-10. PMID:23272190. |
differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals. |
2013-06-10 |
2023-08-12 |
rat |
| Bita Moghadda. A mechanistic approach to preventing schizophrenia in at-risk individuals. Neuron. vol 78. issue 1. 2013-06-07. PMID:23583102. |
(2013) report that excess hippocampal glutamate may cause transition to psychosis in individuals at high risk for schizophrenia. |
2013-06-07 |
2023-08-12 |
Not clear |
| Scott A Schobel, Nashid H Chaudhury, Usman A Khan, Beatriz Paniagua, Martin A Styner, Iris Asllani, Benjamin P Inbar, Cheryl M Corcoran, Jeffrey A Lieberman, Holly Moore, Scott A Smal. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Neuron. vol 78. issue 1. 2013-06-07. PMID:23583108. |
imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. |
2013-06-07 |
2023-08-12 |
mouse |
| Scott A Schobel, Nashid H Chaudhury, Usman A Khan, Beatriz Paniagua, Martin A Styner, Iris Asllani, Benjamin P Inbar, Cheryl M Corcoran, Jeffrey A Lieberman, Holly Moore, Scott A Smal. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Neuron. vol 78. issue 1. 2013-06-07. PMID:23583108. |
these findings show that hippocampal hypermetabolism leads to atrophy in psychotic disorder and suggest glutamate as a pathogenic driver. |
2013-06-07 |
2023-08-12 |
mouse |
| Ana P Herrmann, Paula Lunardi, Luísa Klaus Pilz, Ana C Tramontina, Viviane M Linck, Christopher O Okunji, Carlos A Gonçalves, Elaine Elisabetsk. Effects of the putative antipsychotic alstonine on glutamate uptake in acute hippocampal slices. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:22940693. |
effects of the putative antipsychotic alstonine on glutamate uptake in acute hippocampal slices. |
2013-06-05 |
2023-08-12 |
Not clear |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
hippocampal glutamate level and glutamate aspartate transporter (glast) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. |
2013-05-29 |
2023-08-12 |
rat |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
hippocampal glutamate concentrations in microdialysates were determined by high-performance liquid chromatography. |
2013-05-29 |
2023-08-12 |
rat |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
the intra-anesthesia hippocampal glutamate levels were significantly lower than those of non-anesthesized rats. |
2013-05-29 |
2023-08-12 |
rat |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
we found a continuous raised hippocampal glutamate and an up-regulation of glast rather than glt-1, nmdar1, nmdar2a/b, ampar or tau in hippocampus of aged rats associated with isoflurane-induced learning/memory impairment. |
2013-05-29 |
2023-08-12 |
rat |
| Hee Jung Kim, Tae Hyeong Kim, Se Joon Choi, Yi Jae Hong, Ji Seon Yang, Ki-Wug Sung, Duck-Joo Rhie, Sang June Hahn, Shin Hee Yoo. Fluoxetine suppresses synaptically induced [Ca²⁺]i spikes and excitotoxicity in cultured rat hippocampal neurons. Brain research. vol 1490. 2013-05-29. PMID:23131584. |
collectively, our results suggest that fluoxetine suppresses the spikes and protects neurons against excitotoxicity, particularly in cultured rat hippocampal neurons, presumably due to both direct inhibition of presynaptic glutamate release and postsynaptic glutamate receptor-mediated [ca(2+)](i) signaling. |
2013-05-29 |
2023-08-12 |
rat |
| Takeshi Kanno, Tomoyuki Nishizak. A(2a) adenosine receptor mediates PKA-dependent glutamate release from synaptic-like vesicles and Ca(2+) efflux from an IP(3)- and ryanodine-insensitive intracellular calcium store in astrocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 30. issue 6. 2013-05-29. PMID:23154210. |
the present study examined a(2a) adenosine receptor-mediated glutamate release and intracellular ca(2+) rise in cultured rat hippocampal astrocytes. |
2013-05-29 |
2023-08-12 |
rat |
| Wei Xu, Yiu Chung Tse, Frederick A Dobie, Michel Baudry, Ann Marie Craig, Tak Pan Wong, Yu Tian Wan. Simultaneous monitoring of presynaptic transmitter release and postsynaptic receptor trafficking reveals an enhancement of presynaptic activity in metabotropic glutamate receptor-mediated long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 13. 2013-05-23. PMID:23536098. |
using this method to investigate presynaptic changes during the expression of group i metabotropic glutamate receptor (mglur1/5)-mediated long-term depression (ltd) in cultured rat hippocampal neurons, we discovered that this form of ltd was associated with increased presynaptic release of glutamate, despite reduced miniature epscs measured with whole-cell recording. |
2013-05-23 |
2023-08-12 |
rat |
| Justin P Kinney, Josef Spacek, Thomas M Bartol, Chandrajit L Bajaj, Kristen M Harris, Terrence J Sejnowsk. Extracellular sheets and tunnels modulate glutamate diffusion in hippocampal neuropil. The Journal of comparative neurology. vol 521. issue 2. 2013-05-21. PMID:22740128. |
extracellular sheets and tunnels modulate glutamate diffusion in hippocampal neuropil. |
2013-05-21 |
2023-08-12 |
rat |