| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Norio Takagi, Shintaro Besshoh, Tetsuro Marunouchi, Satoshi Takeo, Kouichi Tanonak. Metabotropic glutamate receptor 5 activation enhances tyrosine phosphorylation of the N-methyl-D-aspartate (NMDA) receptor and NMDA-induced cell death in hippocampal cultured neurons. Biological & pharmaceutical bulletin. vol 35. issue 12. 2013-05-21. PMID:23207774. |
metabotropic glutamate receptor 5 activation enhances tyrosine phosphorylation of the n-methyl-d-aspartate (nmda) receptor and nmda-induced cell death in hippocampal cultured neurons. |
2013-05-21 |
2023-08-12 |
Not clear |
| K A Gleason, S G Birnbaum, A Shukla, S Ghos. Susceptibility of the adolescent brain to cannabinoids: long-term hippocampal effects and relevance to schizophrenia. Translational psychiatry. vol 2. 2013-05-16. PMID:23188199. |
metabotropic glutamate receptors type 5 (mglur5), a receptor critically involved in fear conditioning and endocannabinoid (ecb) signaling, is significantly reduced in the acu mouse hippocampus. |
2013-05-16 |
2023-08-12 |
mouse |
| Francisco J Rubio, Estíbaliz Ampuero, Rodrigo Sandoval, Jorge Toledo, Floria Pancetti, Ursula Wyneke. Long-term fluoxetine treatment induces input-specific LTP and LTD impairment and structural plasticity in the CA1 hippocampal subfield. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675317. |
to unravel the functional significance of such a synaptic re-arrangement, we focused on glutamate neurotransmission in the hippocampus. |
2013-05-16 |
2023-08-12 |
rat |
| Hitomi Hino, Hisaaki Takahashi, Yuka Suzuki, Junya Tanaka, Eiichi Ishii, Mitsumasa Fukud. Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children. PloS one. vol 7. issue 8. 2013-05-15. PMID:22916181. |
in cultured hippocampal neurons, pf suppressed glutamate-induced elevation of intracellular ca(2+) ([ca(2+)](i)), glutamate receptor-mediated membrane depolarization, and glutamate-induced neuronal death. |
2013-05-15 |
2023-08-12 |
human |
| Phil-Ok Ko. Ferulic acid prevents the cerebral ischemic injury-induced decreases of astrocytic phosphoprotein PEA-15 and its two phosphorylated forms. Neuroscience letters. vol 511. issue 2. 2013-05-07. PMID:22306184. |
glutamate exposure induced significant reductions in the levels of pea-15 and the two phospho-pea-15 (ser 104 and ser 116) in cultured hippocampal neuron, while pretreatment with ferulic acid prevented the glutamate toxicity-induced decreases in these proteins levels. |
2013-05-07 |
2023-08-12 |
rat |
| Juan D Pita-Almenar, Shengwei Zou, Costa M Colbert, Arnold Eski. Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 12. 2013-05-07. PMID:23166293. |
glutamate uptake increases in hippocampal slices during early long-term potentiation (e-ltp) and late long-term potentiation (l-ltp). |
2013-05-07 |
2023-08-12 |
Not clear |
| Juan D Pita-Almenar, Shengwei Zou, Costa M Colbert, Arnold Eski. Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 12. 2013-05-07. PMID:23166293. |
in what cell type in the hippocampus does the increase in glutamate uptake occur? |
2013-05-07 |
2023-08-12 |
Not clear |
| Juan D Pita-Almenar, Shengwei Zou, Costa M Colbert, Arnold Eski. Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 12. 2013-05-07. PMID:23166293. |
also, we found that astrocytes were responsible for much, if not all, of the increase in glutamate uptake in hippocampal slices during l-ltp. |
2013-05-07 |
2023-08-12 |
Not clear |
| Juan D Pita-Almenar, Shengwei Zou, Costa M Colbert, Arnold Eski. Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 12. 2013-05-07. PMID:23166293. |
it seems likely that heightened glutamate transport plays an ongoing role in the ability of hippocampal circuitry to code and store information. |
2013-05-07 |
2023-08-12 |
Not clear |
| Maddalena D Caiati, Enrico Cherubin. Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats. Frontiers in cellular neuroscience. vol 7. 2013-05-06. PMID:23641199. |
the immature hippocampus is characterized by an early type of network activity, the so-called giant depolarizing potentials (gdps), generated by the synergistic action of glutamate and gaba, both depolarizing and excitatory. |
2013-05-06 |
2023-08-12 |
human |
| Lara Montes de Oca, Margarita Moreno, Diana Cardona, Leticia Campa, Cristina Suñol, Mireia Galofré, Pilar Flores, Fernando Sánchez-Sante. Long term compulsivity on the 5-choice serial reaction time task after acute Chlorpyrifos exposure. Toxicology letters. vol 216. issue 2-3. 2013-05-03. PMID:23194828. |
the cpf group also exhibited increased levels of dopamine metabolism in the hippocampus and decreased levels of gamma-aminobutyric acid (gaba) and glutamate in the striatum compared to the vehicle group. |
2013-05-03 |
2023-08-12 |
rat |
| Shimo Li, Yoshika Hayakawa-Yano, Masanori Itoh, Masashi Ueda, Kazunori Ohta, Yoshihiro Suzuki, Akihito Mizuno, Eri Ohta, Yoko Hida, Miao-Xing Wang, Toshiyuki Nakagaw. Olfaxin as a novel Prune2 isoform predominantly expressed in olfactory system. Brain research. vol 1488. 2013-05-01. PMID:23059019. |
caytaxin is a substrate of caspase-3 and is specifically expressed at the presynapse of vesicular-type glutamate transporter (vglut)-positive neurons, where it plays a role in glutamate neurotransmission primarily in the cerebellum and hippocampus. |
2013-05-01 |
2023-08-12 |
drosophila_melanogaster |
| Norio Takagi, Shintaro Besshoh, Tetsuro Marunouchi, Satoshi Takeo, Kouichi Tanonak. Effects of metabotropic glutamate mGlu5 receptor antagonist on tyrosine phosphorylation of NMDA receptor subunits and cell death in the hippocampus after brain ischemia in rats. Neuroscience letters. vol 530. issue 1. 2013-04-30. PMID:23022504. |
effects of metabotropic glutamate mglu5 receptor antagonist on tyrosine phosphorylation of nmda receptor subunits and cell death in the hippocampus after brain ischemia in rats. |
2013-04-30 |
2023-08-12 |
rat |
| Aurelien Caballero-Caballero, Tobias Engel, Jaime Martinez-Villarreal, Amaya Sanz-Rodriguez, Patrick Chang, Mark Dunleavy, Claire M Mooney, Eva M Jimenez-Mateos, Clara K Schindler, David C Henshal. Mitochondrial localization of the forkhead box class O transcription factor FOXO3a in brain. Journal of neurochemistry. vol 124. issue 6. 2013-04-29. PMID:23278239. |
over-expression of a mitochondrially targeted foxo3a fusion protein in ht22 cells, but not primary hippocampal neurons, conferred superior protection against glutamate toxicity than foxo3a alone. |
2013-04-29 |
2023-08-12 |
mouse |
| Lara Costa, Michela Spatuzza, Simona D'Antoni, Carmela M Bonaccorso, Chiara Trovato, Sebastiano A Musumeci, Marcello Leopoldo, Enza Lacivita, Maria V Catania, Lucia Cirann. Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome. Biological psychiatry. vol 72. issue 11. 2013-04-23. PMID:22817866. |
fmr1 knockout (fmr1 ko) mice, an animal model of fxs, exhibit spatial memory impairment and synapse malfunctioning in the hippocampus, with abnormal enhancement of long-term depression mediated by metabotropic glutamate receptors (mglur-ltd). |
2013-04-23 |
2023-08-12 |
mouse |
| J Yamada, S Jinn. Upregulation of calcium binding protein, S100A6, in activated astrocytes is linked to glutamate toxicity. Neuroscience. vol 226. 2013-04-22. PMID:22982625. |
we first examined the age-related changes in s100a6 immunoreactivity in the mouse hippocampus, considering that an important negative aspect of brain aging is linked to increased extracellular glutamate. |
2013-04-22 |
2023-08-12 |
mouse |
| N Gupta, Y Jing, N D Collie, H Zhang, P Li. Ageing alters behavioural function and brain arginine metabolism in male Sprague-Dawley rats. Neuroscience. vol 226. 2013-04-22. PMID:22989918. |
there were significant age-related changes in nos and arginase activities, and the levels of l-arginine, l-citrulline, l-ornithine, agmatine, putrescine, spermidine, spermine and glutamate, but not γ-aminobutyric acid, in the ca1, ca2/3 and dentate gyrus sub-regions of the hippocampus and the prefrontal, entorhinal, perirhinal, postrhinal and temporal (an auditory cortex) cortices in a region-specific manner. |
2013-04-22 |
2023-08-12 |
rat |
| Mohan Raghavan, Bharadwaj Amrutur, Kalyan V Srinivas, Sujit K Sikda. A study of epileptogenic network structures in rat hippocampal cultures using first spike latencies during synchronization events. Physical biology. vol 9. issue 5. 2013-04-19. PMID:22878674. |
using rat hippocampal neurons cultured on a multi-electrode array dish and a glutamate injury model of epilepsy in vitro, we studied synchronous activity in neuronal networks. |
2013-04-19 |
2023-08-12 |
rat |
| C Fabrizi, F Somma, E Pompili, F Biagioni, P Lenzi, F Fornai, L Fumagall. Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 11. 2013-04-18. PMID:22415064. |
when lithium was administered according to a chronic treatment protocol (6 days pretreatment) it was able to rescue both hippocampal and cortical neurons from tmt (or from glutamate toxicity used as reference). |
2013-04-18 |
2023-08-12 |
Not clear |
| Aino Vesikansa, Prasanna Sakha, Juha Kuja-Panula, Svetlana Molchanova, Claudio Rivera, Henri J Huttunen, Heikki Rauvala, Tomi Taira, Sari E Laur. Expression of GluK1c underlies the developmental switch in presynaptic kainate receptor function. Scientific reports. vol 2. 2013-04-12. PMID:22413061. |
these data support a central role for gluk1c in mediating tonic inhibition of glutamate release and the consequent effects on excitability and activity-dependent fine-tuning of the developing hippocampal circuitry. |
2013-04-12 |
2023-08-12 |
Not clear |