| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
in the present study the effects of multiple injections of mdma on extracellular concentrations of glutamate in the striatum, prefrontal cortex, and dorsal hippocampus were examined. |
2013-01-10 |
2023-08-12 |
rat |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
at 2 h intervals) resulted in a 2-3 fold increase in the extracellular concentration of glutamate in the hippocampus; no increase was evident in the striatum or prefrontal cortex. |
2013-01-10 |
2023-08-12 |
rat |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
reverse dialysis of mdma (100 μm) into the hippocampus also elicited an increase in extracellular glutamate. |
2013-01-10 |
2023-08-12 |
rat |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
treatment with the 5-ht reuptake inhibitor fluoxetine prevented the increase in extracellular glutamate in the hippocampus following the systemic administration of mdma, as did treatment with the serotonin 5-ht2a/c receptor antagonist ketanserin. |
2013-01-10 |
2023-08-12 |
rat |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
moreover, reverse dialysis of the sodium channel blocker tetrodotoxin did not prevent the increase in extracellular glutamate in the hippocampus. |
2013-01-10 |
2023-08-12 |
rat |
| John H Anneken, Gary A Gudelsk. MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22842073. |
these data support the view that stimulation of 5-ht2a/2c receptors on non-neuronal cells by 5-ht released by mdma promotes glutamate efflux in the hippocampus. |
2013-01-10 |
2023-08-12 |
rat |
| Guoxiang Xiong, Lei Zhang, Jelena Mojsilovic-Petrovic, Edguardo Arroyo, Jaclynn Elkind, Suhali Kundu, Brian Johnson, Colin J Smith, Noam A Cohen, Sean M Grady, Akiva S Cohe. GABA and glutamate are not colocalized in mossy fiber terminals of developing rodent hippocampus. Brain research. vol 1474. 2013-01-08. PMID:22842523. |
gaba and glutamate are not colocalized in mossy fiber terminals of developing rodent hippocampus. |
2013-01-08 |
2023-08-12 |
mouse |
| Guoxiang Xiong, Lei Zhang, Jelena Mojsilovic-Petrovic, Edguardo Arroyo, Jaclynn Elkind, Suhali Kundu, Brian Johnson, Colin J Smith, Noam A Cohen, Sean M Grady, Akiva S Cohe. GABA and glutamate are not colocalized in mossy fiber terminals of developing rodent hippocampus. Brain research. vol 1474. 2013-01-08. PMID:22842523. |
it has been hypothesized that, in the developing rodent hippocampus, mossy fiber terminals release gaba together with glutamate. |
2013-01-08 |
2023-08-12 |
mouse |
| Q Zhang, M Ding, X R Gao, F Din. Pyrroloquinoline quinone rescues hippocampal neurons from glutamate-induced cell death through activation of Nrf2 and up-regulation of antioxidant genes. Genetics and molecular research : GMR. vol 11. issue 3. 2013-01-08. PMID:22843070. |
immunostaining and quantitative rt-pcr revealed that pqq treatment promotes nuclear translocation of nuclear factor erythroid 2-related factor 2 (nrf2), and up-regulates mrna expression of nrf2 and the antioxidant enzyme genes, heme oxygenase-1 and glutamate cysteine ligase catalytic in glutamate-injured hippocampal neurons; this is a process dependent on the pi3k/akt pathway, as evidenced by blocking experiments with pi3k inhibitors. |
2013-01-08 |
2023-08-12 |
Not clear |
| Sarah Biedermann, Wolfgang Weber-Fahr, Lei Zheng, Carolin Hoyer, Barbara Vollmayr, Peter Gass, Gabriele Ende, Alexander Sartoriu. Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 13. issue 6. 2013-01-07. PMID:21767208. |
increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton mr spectroscopy study at 9.4 t in an animal model of depression. |
2013-01-07 |
2023-08-12 |
Not clear |
| Sarah Biedermann, Wolfgang Weber-Fahr, Lei Zheng, Carolin Hoyer, Barbara Vollmayr, Peter Gass, Gabriele Ende, Alexander Sartoriu. Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 13. issue 6. 2013-01-07. PMID:21767208. |
recent evidence suggests that alterations in hippocampal glutamate and γ-aminobutyric acid (gaba) are associated with the pathomechanism of depression and treatment effects of electroconvulsive therapy (ect). |
2013-01-07 |
2023-08-12 |
Not clear |
| Magdalena Dziembowska, Jacek Milek, Aleksandra Janusz, Emilia Rejmak, Ewelina Romanowska, Tomasz Gorkiewicz, Adrian Tiron, Clive R Bramham, Leszek Kaczmare. Activity-dependent local translation of matrix metalloproteinase-9. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 42. 2013-01-02. PMID:23077039. |
first, dendritic transport of mmp-9 mrna was seen in primary hippocampal neuronal cultures treated with glutamate and in dentate gyrus granule cells in adult anesthetized rats after induction of long-term potentiation. |
2013-01-02 |
2023-08-12 |
rat |
| Magdalena Dziembowska, Jacek Milek, Aleksandra Janusz, Emilia Rejmak, Ewelina Romanowska, Tomasz Gorkiewicz, Adrian Tiron, Clive R Bramham, Leszek Kaczmare. Activity-dependent local translation of matrix metalloproteinase-9. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 42. 2013-01-02. PMID:23077039. |
third, glutamate stimulation of cultured hippocampal neurons evoked a rapid (in minutes) increase in mmp-9 activity, as measured by cleavage of its native substrate, β-dystroglycan. |
2013-01-02 |
2023-08-12 |
rat |
| Linn H Nilsen, Torun M Melø, Oddbjørn Saether, Menno P Witter, Ursula Sonnewal. Altered neurochemical profile in the McGill-R-Thy1-APP rat model of Alzheimer's disease: a longitudinal in vivo 1 H MRS study. Journal of neurochemistry. vol 123. issue 4. 2012-12-21. PMID:22943908. |
at age 9 months, lower levels of glutamate, gaba, n-acetylaspartate and total choline and elevated myo-inositol and taurine were found in dorsal hippocampus, whereas lower levels of glutamate, gaba, glutamine and n-acetylaspartate were found in frontal cortex. |
2012-12-21 |
2023-08-12 |
rat |
| Sandra L Silva, Ana R Vaz, Maria J Diógenes, Nico van Rooijen, Ana M Sebastião, Adelaide Fernandes, Rui F M Silva, Dora Brite. Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22361233. |
data from organotypic-cultured hippocampal slices, depleted or non-depleted in microglia, supported that microglia participate in glutamate homeostasis and contribute to no production and cell demise, which were again abrogated by gudca. |
2012-12-20 |
2023-08-12 |
Not clear |
| C Wirth, F Schubert, M Lautenschlager, R Brühl, A Klär, T Majic, U E Lang, A Ehrlich, G Winterer, T Sander, M Schouler-Ocak, J Gallina. DTNBP1 (dysbindin) gene variants: in vivo evidence for effects on hippocampal glutamate status. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283763. |
dtnbp1 (dysbindin) gene variants: in vivo evidence for effects on hippocampal glutamate status. |
2012-12-18 |
2023-08-12 |
Not clear |
| C Wirth, F Schubert, M Lautenschlager, R Brühl, A Klär, T Majic, U E Lang, A Ehrlich, G Winterer, T Sander, M Schouler-Ocak, J Gallina. DTNBP1 (dysbindin) gene variants: in vivo evidence for effects on hippocampal glutamate status. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283763. |
in vitro and animal models provide evidence that the dtnbp1 gene product dysbindin modulates the activity of the neurotransmitter glutamate in hippocampal neurons and is crucial for cell functioning and synaptogenesis. |
2012-12-18 |
2023-08-12 |
Not clear |
| C Wirth, F Schubert, M Lautenschlager, R Brühl, A Klär, T Majic, U E Lang, A Ehrlich, G Winterer, T Sander, M Schouler-Ocak, J Gallina. DTNBP1 (dysbindin) gene variants: in vivo evidence for effects on hippocampal glutamate status. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283763. |
this study is the first to investigate the effects of genetic variants of dtnbp1 on the status of the glutamate system as well as neuronal integrity (n-acetylaspartate, naa) in the hippocampus and a cortical region, the anterior cingulate cortex (acc), in humans. |
2012-12-18 |
2023-08-12 |
Not clear |
| Zhengyu Cao, Susan Hulsizer, Flora Tassone, Hiu-tung Tang, Randi J Hagerman, Michael A Rogawski, Paul J Hagerman, Isaac N Pessa. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Human molecular genetics. vol 21. issue 13. 2012-12-13. PMID:22466801. |
precgg neurons have reduced expression of vesicular gaba and glutamate (glu) transporters (vgat and vglut1, respectively), and precgg hippocampal astrocytes display a rightward shift on glu uptake kinetics, compared with wt. |
2012-12-13 |
2023-08-12 |
mouse |
| Jyotirmoy Banerjee, Manickavasagom Alkondon, Edson X Albuquerqu. Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms. Biochemical pharmacology. vol 84. issue 8. 2012-12-13. PMID:22889930. |
in vivo studies indicate that in the hippocampus kyna decreases glutamate levels, presumably via inhibition of α7 nicotinic receptors (nachrs). |
2012-12-13 |
2023-08-12 |
rat |