| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jyotirmoy Banerjee, Manickavasagom Alkondon, Edson X Albuquerqu. Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms. Biochemical pharmacology. vol 84. issue 8. 2012-12-13. PMID:22889930. |
here we tested the hypothesis that basal synaptic glutamate activity in the hippocampus is regulated by tonically active α7 nachrs and is sensitive to inhibition by kyna. |
2012-12-13 |
2023-08-12 |
rat |
| Rong-Fang Feng, Wen-Bin Li, Hui-Qing Liu, Qing-Jun Li, Xiao-Ling Chen, Ai-Min Zhou, Hong-Gang Zhao, Jie A. [Effects of the metabotropic glutamate receptor ligand(s)-4C3HPG on the induction of brain ischemic tolerance in the rat]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 19. issue 1. 2012-12-07. PMID:21207849. |
to explore roles of metabotropic glutamate receptor1/5 (mglur1/5) in the induction of brain ischemic tolerance (bit) induced by cerebral ischemic preconditioning (cip), influences of mglur1/5 ligand (s)-4-carboxy-3-hydroxy- phenylglycine ((s)-4c3hpg) on the induction of bit and expression of glial fibrillary acidic protein (gfap) in the hippocampus were observed. |
2012-12-07 |
2023-08-12 |
rat |
| S J López-Pérez, A Morales-Villagrán, J Ventura-Valenzuela, L Medina-Cej. Short- and long-term changes in extracellular glutamate and acetylcholine concentrations in the rat hippocampus following hypoxia. Neurochemistry international. vol 61. issue 2. 2012-12-07. PMID:22465687. |
short- and long-term changes in extracellular glutamate and acetylcholine concentrations in the rat hippocampus following hypoxia. |
2012-12-07 |
2023-08-12 |
rat |
| S J López-Pérez, A Morales-Villagrán, J Ventura-Valenzuela, L Medina-Cej. Short- and long-term changes in extracellular glutamate and acetylcholine concentrations in the rat hippocampus following hypoxia. Neurochemistry international. vol 61. issue 2. 2012-12-07. PMID:22465687. |
alterations in the extracellular turnover of glutamate (glu) and acetylcholine (ach), two neurotransmitters that are essential for normal hippocampal function and learning and memory processes, may contribute to some of the neurological effects of perinatal hypoxia. |
2012-12-07 |
2023-08-12 |
rat |
| X L Lou, J D Hao, C G Zh. [Calcium signals induced by glutamate in rat hippocampal neurons]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 1. 2012-12-03. PMID:21171430. |
[calcium signals induced by glutamate in rat hippocampal neurons]. |
2012-12-03 |
2023-08-12 |
rat |
| Rokuya Nochi, Tomomasa Kato, Jun Kaneko, Yoshie Itou, Hiroshi Kuribayashi, Satoshi Fukuda, Yasushi Terazono, Ayumu Matani, Shigeaki Kanatani, Kazunori Nakajima, Tatsuhiro Hisatsun. Involvement of metabotropic glutamate receptor 5 signaling in activity-related proliferation of adult hippocampal neural stem cells. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22591399. |
involvement of metabotropic glutamate receptor 5 signaling in activity-related proliferation of adult hippocampal neural stem cells. |
2012-11-30 |
2023-08-12 |
mouse |
| G A Romanova, Yu N Kvashennikova, F M Shakova, T V Davydov. Effect of antibodies to glutamate on the content of neurotransmitter amino acids in brain structures of rats with ischemic damage to the prefrontal cortex. Bulletin of experimental biology and medicine. vol 153. issue 1. 2012-11-28. PMID:22808482. |
experiments on the model of bilateral photothrombosis in the prefrontal cortex showed that antibodies to glutamate administered intranasally 1 h after ischemic damage to the brain cortex led to a decrease in glutamate content in the hippocampus and prefrontal cortex and had no effect on aspartate concentration in these structures of the brain. |
2012-11-28 |
2023-08-12 |
rat |
| Xiaofen Zhong, Hongda Li, Qiang Chan. MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 37. 2012-11-28. PMID:22973007. |
we show here that mecp2 phosphorylation is specifically required for bicuculline-induced synaptic scaling down in mouse hippocampal neurons and this phenotype is mediated by mglur5 (metabotropic glutamate receptor 5). |
2012-11-28 |
2023-08-12 |
mouse |
| D E Warren, P E Bickler, J P Clark, M Gregersen, H Brosnan, W McKleroy, P Gabatt. Hypothermia and rewarming injury in hippocampal neurons involve intracellular Ca2+ and glutamate excitotoxicity. Neuroscience. vol 207. 2012-11-27. PMID:22265728. |
hypothermia and rewarming injury in hippocampal neurons involve intracellular ca2+ and glutamate excitotoxicity. |
2012-11-27 |
2023-08-12 |
rat |
| F Molinari, A A Cattani, J B Mdzomba, L Aniksztej. Glutamate transporters control metabotropic glutamate receptors activation to prevent the genesis of paroxysmal burst in the developing hippocampus. Neuroscience. vol 207. 2012-11-27. PMID:22326967. |
glutamate transporters control metabotropic glutamate receptors activation to prevent the genesis of paroxysmal burst in the developing hippocampus. |
2012-11-27 |
2023-08-12 |
human |
| F Molinari, A A Cattani, J B Mdzomba, L Aniksztej. Glutamate transporters control metabotropic glutamate receptors activation to prevent the genesis of paroxysmal burst in the developing hippocampus. Neuroscience. vol 207. 2012-11-27. PMID:22326967. |
our data show that an insufficient buffering of extracellular glutamate enables a cross talk between groups i/ii mglur and nmdar, which, combined with a decrease of i(sahp), leads to the hyperexcitability of the hippocampal network, facilitating the genesis of epileptical-like activity in response to glutamate release. |
2012-11-27 |
2023-08-12 |
human |
| Sang-Young Kim, Eun-Ju Jang, Kwan Su Hong, Chulhyun Lee, Do-Wan Lee, Chi-Bong Choi, Hyunseung Lee, Bo-Young Cho. Acute restraint-mediated increases in glutamate levels in the rat brain: an in vivo ¹H-MRS study at 4.7 T. Neurochemical research. vol 37. issue 4. 2012-11-26. PMID:22187117. |
we found that acute restraint stress induced significant increase in glutamate concentrations in the cerebral cortex and the hippocampus of rat. |
2012-11-26 |
2023-08-12 |
rat |
| Manavi Chatterjee, Seema Singh, Reena Kumari, Anil Kumar Verma, Gautam Pali. Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice. Neurochemical research. vol 37. issue 4. 2012-11-26. PMID:22189635. |
in addition, pq extract reduced acetylcholinesterase activity and nitrate levels, however increased glutamate levels in hippocampus. |
2012-11-26 |
2023-08-12 |
mouse |
| Matthew K Brittain, Tatiana Brustovetsky, Patrick L Sheets, Joel M Brittain, Rajesh Khanna, Theodore R Cummins, Nickolay Brustovetsk. Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger. Neurobiology of disease. vol 46. issue 1. 2012-11-20. PMID:22249110. |
in rat cultured hippocampal neurons, 25 μm glutamate produced dcd accompanied by sustained increase in cytosolic na+ ([na+]c) and plasma membrane depolarization. |
2012-11-20 |
2023-08-12 |
rat |
| Eunsil Cho, Kyung Jin Lee, Jung-Woo Seo, Catherine Jeonghae Byun, Sun-Ju Chung, Dae Chul Suh, Peter Carmeliet, Jae-Young Koh, Jong S Kim, Joo-Yong Le. Neuroprotection by urokinase plasminogen activator in the hippocampus. Neurobiology of disease. vol 46. issue 1. 2012-11-20. PMID:22293605. |
moreover, recombinant upa suppressed cell death in primary cultures of hippocampal neurons exposed to h2o2, zinc, or various excitotoxins, suggesting that upa protects against neuronal injuries mediated by the glutamate receptor, or by oxidation- or zinc-induced death signaling pathways. |
2012-11-20 |
2023-08-12 |
mouse |
| Lawrence P Reagan, Leah R Reznikov, Ashlie N Evans, Cecilia Gabriel, Elisabeth Mocaër, Jim R Fade. The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain research. vol 1466. 2012-11-20. PMID:22647752. |
in the hippocampus, acute stress increases glutamate efflux and elicits an oscillatory pattern of gaba efflux. |
2012-11-20 |
2023-08-12 |
rat |
| Lawrence P Reagan, Leah R Reznikov, Ashlie N Evans, Cecilia Gabriel, Elisabeth Mocaër, Jim R Fade. The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain research. vol 1466. 2012-11-20. PMID:22647752. |
agomelatine administration (40mg/kg ip) prior to acute stress inhibited stress-mediated increases in glutamate efflux in the hippocampus, bla and cea. |
2012-11-20 |
2023-08-12 |
rat |
| Lawrence P Reagan, Leah R Reznikov, Ashlie N Evans, Cecilia Gabriel, Elisabeth Mocaër, Jim R Fade. The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain research. vol 1466. 2012-11-20. PMID:22647752. |
these results demonstrate that acute agomelatine administration effectively inhibits acute stress-mediated changes in extracellular glutamate in the rat hippocampus and amygdala. |
2012-11-20 |
2023-08-12 |
rat |
| Yasuhiro Kakazu, Jin-Young Koh, Sadahiro Iwabuchi, Pedro Gonzalez-Alegre, N Charles Harat. Miniature release events of glutamate from hippocampal neurons are influenced by the dystonia-associated protein torsinA. Synapse (New York, N.Y.). vol 66. issue 9. 2012-11-19. PMID:22588999. |
miniature release events of glutamate from hippocampal neurons are influenced by the dystonia-associated protein torsina. |
2012-11-19 |
2023-08-12 |
mouse |
| Kenichi Tokita, Yuko Fujita, Takayuki Yamaji, Kenji Hashimot. Depressive-like behavior in adrenocorticotropic hormone-treated rats blocked by memantine. Pharmacology, biochemistry, and behavior. vol 102. issue 2. 2012-11-19. PMID:22609796. |
compared with control rats, glutamine, glycine, l-serine, and d-serine levels were increased in the hippocampus of acth-treated rats; glutamate, glutamine, glycine, l-serine, and d-serine were increased in the cerebellum; and glutamine and glycine were increased in the frontal cortex and striatum, all with statistical significance. |
2012-11-19 |
2023-08-12 |
rat |