| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isadora Matias, Luan Pereira Diniz, Ana Paula Bergamo Araujo, Isabella Vivarini Damico, Pâmella de Moura, Felipe Cabral-Miranda, Fabiola Diniz, Belisa Parmeggiani, Valeria de Mello Coelho, Renata E P Leite, Claudia K Suemoto, Gustavo Costa Ferreira, Regina Célia Cussa Kubrusly, Flávia Carvalho Alcantara Gome. Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus. ASN neuro. vol 15. 2023-02-23. PMID:36815213. |
age-associated upregulation of glutamate transporters and glutamine synthetase in senescent astrocytes in vitro and in the mouse and human hippocampus. |
2023-02-23 |
2023-08-14 |
mouse |
| Tomohiko Maruo, Kiyohito Mizutani, Muneaki Miyata, Toshihiko Kuriu, Shotaro Sakakibara, Hatena Takahashi, Daichi Kida, Kouki Maesaka, Tsukiko Sugaya, Ayuko Sakane, Takuya Sasaki, Yoshimi Takai, Kenji Manda. s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons. The Journal of biological chemistry. 2023-02-21. PMID:36803960. |
our electrophysiological analysis revealed that the postsynaptic response to glutamate, but not its release from the presynapse, was impaired in the maguin-deficient cultured hippocampal neurons. |
2023-02-21 |
2023-08-14 |
Not clear |
| Pelin Saglam-Metiner, Utku Devamoglu, Yagmur Filiz, Soheil Akbari, Goze Beceren, Bakiye Goker, Burcu Yaldiz, Sena Yanasik, Cigir Biray Avci, Esra Erdal, Ozlem Yesil-Celikta. Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids. Communications biology. vol 6. issue 1. 2023-02-14. PMID:36788328. |
rccs and µ-platform organoids have reached ideal sizes, approximately 95% harvestability, prolonged culture time with ki-67 + /cd31 + /β-catenin+ proliferative, adhesive and endothelial-like cells and exhibited enriched cellular diversity (abundant neural/glial/ endothelial cell population), structural brain morphogenesis, further functional neuronal identities (glutamate secreting glutamatergic, gabaergic and hippocampal neurons) and synaptogenesis (presynaptic-postsynaptic interaction) during whole human brain development. |
2023-02-14 |
2023-08-14 |
human |
| Pawel Grochecki, Irena Smaga, Karolina Wydra, Marta Marszalek-Grabska, Tymoteusz Slowik, Ewa Kedzierska, Joanna Listos, Ewa Gibula-Tarlowska, Malgorzata Filip, Jolanta H Kotlinsk. Impact of Mephedrone on Fear Memory in Adolescent Rats: Involvement of Matrix Metalloproteinase-9 (MMP-9) and N-Methyl-D-aspartate (NMDA) Receptor. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768263. |
we also analyzed whether these trauma-induced changes were associated with exacerbation in metalloproteinase-9 (mmp-9) and the glun2a and glun2b subunits of n-methyl-d-aspartate (nmda) glutamate receptor expression in such brain structures as the hippocampus and basolateral amygdala. |
2023-02-11 |
2023-08-14 |
rat |
| Yanhui Hao, Weiqi Liu, Yujie Liu, Ying Liu, Zhengtao Xu, Yumeng Ye, Hongmei Zhou, Hua Deng, Hongyan Zuo, Hong Yang, Yang L. Effects of Nonthermal Radiofrequency Stimulation on Neuronal Activity and Neural Circuit in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-02-09. PMID:36755196. |
glutamate release in the dorsal hippocampus (dhpc) ca1 region is not significantly changed after radiofrequency exposure, whereas dopamine release is reduced. |
2023-02-09 |
2023-08-14 |
mouse |
| Wenjuan Zhou, Chen Zhang, Peipei Wang, Yuanying Deng, Hongmei Dai, Jing Tian, Guojiao Wu, Lingling Zha. Chlorpyrifos-induced dysregulation of synaptic plasticity in rat hippocampal neurons. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2023-02-01. PMID:36722685. |
using cpf-exposed rat and primary hippocampal neurons model, we analyzed the impact of cpf on the synaptic morphology, the expression level of a presynaptic protein, a postsynaptic protein and ionotropic glutamate receptors (iglurs), as well as the effects on the wnt/β-catenin pathway. |
2023-02-01 |
2023-08-14 |
rat |
| Shuyue Cheng, Jingjing Xu, Wei Wang, Rui Wang, Haonan Li, Zhijun Jiang, Dexiang Liu, Fang Pa. Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats. Psychopharmacology. 2023-02-01. PMID:36725696. |
previous studies have shown that traumatic stress changes metabotropic glutamate receptor 5 (mglur5) expression in the hippocampus (hip) and prefrontal cortex (pfc). |
2023-02-01 |
2023-08-14 |
rat |
| Jia Guo, Douglas L Rothman, Scott A Smal. Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia. JAMA psychiatry. 2023-01-25. PMID:36696108. |
why hippocampal glutamate levels are elevated in schizophrenia. |
2023-01-25 |
2023-08-14 |
Not clear |
| Zhinei Tan, Yongxia Li, Yinzheng Guan, Javed Iqbal, Chenyue Wang, Riqiang Yan, Xin-Ming M. Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience in Rats. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674721. |
our results showed that kl is regulated by estrogen in rat hippocampal neurons in vivo and in vitro and is essential for the estrogen-mediated increase in the number of presynaptic vesicular glutamate transporter 1 (vglut1)-positive clusters on the dendrites of hippocampal neurons. |
2023-01-21 |
2023-08-14 |
rat |
| Qin-Wei Wu, Zheng-Quan Tan. Focusing on the Emerging Role of Kainate Receptors in the Dorsal Cochlear Nucleus (DCN) and Cerebellum. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675230. |
kainate receptors (kars) are one class of the glutamate receptor family and are strongly expressed in the hippocampus, the cerebellum, and cerebellum-like structures. |
2023-01-21 |
2023-08-14 |
Not clear |
| Anant Jain, Catherine S Woolle. Mechanisms that underlie expression of estradiol-induced excitatory synaptic potentiation in the hippocampus differ between males and females. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-01-17. PMID:36650060. |
here, we used electrical stimulation and two-photon glutamate uncaging in hippocampal slices from adult male and female rats to investigate whether the downstream consequences of distinct molecular signaling remain different between the sexes or converge to the same mechanism(s) of expression of potentiation. |
2023-01-17 |
2023-08-14 |
rat |
| Javad Karimi Abadchi, Zahra Rezaei, Thomas Knöpfel, Bruce L McNaughton, Majid H Mohajeran. Inhibition is a prevalent mode of activity in the neocortex around awake hippocampal ripples in mice. eLife. vol 12. 2023-01-16. PMID:36645126. |
we addressed this possibility by conducting voltage and glutamate wide-field imaging of the neocortex with concurrent hippocampal electrophysiology in awake mice. |
2023-01-16 |
2023-08-14 |
mouse |
| Yoon Ji Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yan. Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices. STAR protocols. vol 4. issue 1. 2023-01-12. PMID:36633949. |
we detail the steps for (1) obtaining acute mouse hippocampal slices that contain longitudinal dg-dg connections, (2) measuring excitatory postsynaptic potentials using whole-cell patch clamp recording combined with two-photon microscopy and glutamate uncaging, and (3) assessing synaptic plasticity using extracellular field recording. |
2023-01-12 |
2023-08-14 |
mouse |
| Yuchen Hao, Estelle Toulmé, Benjamin König, Christian Rosenmund, Andrew J R Pleste. Targeted sensors for glutamatergic neurotransmission. eLife. vol 12. 2023-01-09. PMID:36622100. |
chimeras of stargazin and gamma-8 that we named snfr-γ2 and snfr-γ8, were enriched at synapses, retained function and reported spontaneous glutamate release in rat hippocampal cells, with apparently diffraction-limited spatial precision. |
2023-01-09 |
2023-08-14 |
mouse |
| Tatyana Y Postnikova, Dmitry V Amakhin, Alina M Trofimova, Natalia L Tumanova, Nadezhda M Dubrovskaya, Daria S Kalinina, Anna A Kovalenko, Anastasiia D Shcherbitskaia, Dmitry S Vasilev, Aleksey V Zaitse. Maternal Hyperhomocysteinemia Produces Memory Deficits Associated with Impairment of Long-Term Synaptic Plasticity in Young Rats. Cells. vol 12. issue 1. 2023-01-08. PMID:36611852. |
no significant alterations of glutamate receptor subunit expression except glun1 were detected in the hippocampus of hcy rats using the quantitative real-time pcr and western blot methods. |
2023-01-08 |
2023-08-14 |
rat |
| Mohammad Keimasi, Kowsar Salehifard, Marzieh Shahidi, Fariba Esmaeili, Noushin Mirshah Jafar Esfahani, Siamak Beheshti, Mohammadreza Amirsadri, Faezeh Naseri, Mohammadjavad Keimasi, Najmeh Ghorbani, Mohammad Reza Mofid, Majid Moradman. Ameliorative effects of omega-lycotoxin-Gsp2671e purified from the spider venom of Frontiers in pharmacology. vol 13. 2023-01-02. PMID:36588719. |
this condition can be induced by hyper-stimulation of n-methyl-d-aspartate receptors (nmdars) of glutamate in the hippocampus, which ends up to pyramidal neurons determination. |
2023-01-02 |
2023-08-14 |
spider |
| Sukrit Promtang, Chairat Turbpaiboon, Eve Mon Oo, Ladawan Khowawisetsut, Panapat Uawithya, Supin Chompoopon. Germinated brown rice protects against glutamate toxicity in HT22 hippocampal neurons through the jnk-mediated apoptotic pathway via the GABA IBRO neuroscience reports. vol 14. 2023-01-02. PMID:36590249. |
germinated brown rice protects against glutamate toxicity in ht22 hippocampal neurons through the jnk-mediated apoptotic pathway via the gaba the anti-apoptosis effect of germinated brown rice (gbr) focusing on differentiated ht22 cells results in improved nutritional values after the germination process of gbr which contains total phenolic compounds and γ-aminobutyric acid (gaba). |
2023-01-02 |
2023-08-14 |
Not clear |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wan. Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice. Frontiers in molecular neuroscience. vol 15. 2022-12-29. PMID:36578534. |
furthermore, hfd impaired synaptic plasticity and decreased surface expression of glutamate receptors in the hippocampus of wild-type (wt) mice, but not in c/ebpβ heterozygous knockout mice. |
2022-12-29 |
2023-08-14 |
mouse |
| Yingying Jiang, Qingying Liu, Yumei Zhao, Chunyang Wang, Ming Su. Activation of CREB-BDNF Pathway in Pyramidal Neurons in the Hippocampus Improves the Neurological Outcome of Mice with Ischemic Stroke. Molecular neurobiology. 2022-12-26. PMID:36571720. |
however, it is unclear whether glutamate in the ventral hippocampal cornus ammonis 1 (vca1) acts a part in neurological deficits, pain perception, anxiety, and depression induced by ischemic stroke. |
2022-12-26 |
2023-08-14 |
mouse |