| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bethany J Stieve, Madison M Smith, Esther Krook-Magnuso. LINCs are vulnerable to epileptic insult and fail to provide seizure control via on-demand activation. eNeuro. 2023-02-01. PMID:36725340. |
lincs, a population of hippocampal neurons, were recently identified as a unique source of widespread inhibition in ca1, able to elicit both gaba |
2023-02-01 |
2023-08-14 |
Not clear |
| Valentina Licheri, Giuseppe Talani, Giovanni Biggio, Enrico Sann. Bi-directional modulation of hyperpolarization-activated cation currents (I Neuropharmacology. 2023-01-23. PMID:36690323. |
previous work has demonstrated that etoh enhances the firing rate of hippocampal gabaergic interneurons and thus the presynaptic gaba release at ca1 and ca3 inhibitory synapses through a positive modulation of the hyperpolarization-activated cyclic nucleotide-gated cation (hcn) channels. |
2023-01-23 |
2023-08-14 |
Not clear |
| Masoumeh Nazari, Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Kourosh Arami, Alireza Komak. Underlying mechanisms of long-term potentiation during the inhibition of the cannabinoid CB1 and GABAB receptors in the dentate gyrus of hippocampus. BMC neuroscience. vol 24. issue 1. 2023-01-12. PMID:36635629. |
in our previous work, we showed that cb1 antagonists increased the population spike (ps) amplitude, field excitatory post-synaptic potential (fepsp), and the ltp induction in the dentate gyrus (dg) of the rat hippocampus while the gaba |
2023-01-12 |
2023-08-14 |
mouse |
| Sukrit Promtang, Chairat Turbpaiboon, Eve Mon Oo, Ladawan Khowawisetsut, Panapat Uawithya, Supin Chompoopon. Germinated brown rice protects against glutamate toxicity in HT22 hippocampal neurons through the jnk-mediated apoptotic pathway via the GABA IBRO neuroscience reports. vol 14. 2023-01-02. PMID:36590249. |
germinated brown rice protects against glutamate toxicity in ht22 hippocampal neurons through the jnk-mediated apoptotic pathway via the gaba the anti-apoptosis effect of germinated brown rice (gbr) focusing on differentiated ht22 cells results in improved nutritional values after the germination process of gbr which contains total phenolic compounds and γ-aminobutyric acid (gaba). |
2023-01-02 |
2023-08-14 |
Not clear |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Xiao-Hui Tang, Yu-Gang Diao, Zhuo-Yu Ren, Yan-Yu Zang, Guang-Fen Zhang, Xing-Ming Wang, Gui-Fang Duan, Jin-Chun Shen, Kenji Hashimoto, Zhi-Qiang Zhou, Jian-Jun Yan. A role of GABA Neuropharmacology. 2022-12-24. PMID:36565851. |
mice exposed to fss (forced swimming stress) showed depression-like behavior and decreased levels of gaba (γ-aminobutyric acid), but not glutamate, in the hippocampus. |
2022-12-24 |
2023-08-14 |
mouse |
| Xiao-Hui Tang, Yu-Gang Diao, Zhuo-Yu Ren, Yan-Yu Zang, Guang-Fen Zhang, Xing-Ming Wang, Gui-Fang Duan, Jin-Chun Shen, Kenji Hashimoto, Zhi-Qiang Zhou, Jian-Jun Yan. A role of GABA Neuropharmacology. 2022-12-24. PMID:36565851. |
ketamine increased gaba levels and decreased glutamate levels in the hippocampus of mice exposed to fss. |
2022-12-24 |
2023-08-14 |
mouse |
| R Oliver Goral, Kathryn M Harper, Briana J Bernstein, Sydney A Fry, Patricia W Lamb, Sheryl S Moy, Jesse D Cushman, Jerrel L Yake. Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions. Frontiers in behavioral neuroscience. vol 16. 2022-12-12. PMID:36505727. |
loss of gaba co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions. |
2022-12-12 |
2023-08-14 |
Not clear |
| b' Tyciane S Nascimento, Daniel V Pinto, Ronaldo P Dias, Ramon S Raposo, Paulo Iury G Nunes, C\\xc3\\xa1ssia R Roque, Fl\\xc3\\xa1via A Santos, Geanne M Andrade, Jos\\xc3\\xa9 Lucas Viana, Anne H Fostier, Alessandra Sussulini, Jacqueline I Alvarez-Leite, Carlos Fontes-Ribeiro, Jo\\xc3\\xa3o O Malva, Reinaldo B Ori\\xc3\\xa. Chronic Methylmercury Intoxication Induces Systemic Inflammation, Behavioral, and Hippocampal Amino Acid Changes in C57BL6J Adult Mice. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430321.' |
mehg-intoxication led to increased gaba and glycine, reduced hippocampal taurine levels, delayed acquisition in the barnes maze, and poor locomotor activity. |
2022-11-26 |
2023-08-14 |
mouse |
| Marta De Felice, Chaochao Chen, Mar Rodríguez-Ruiz, Hanna J Szkudlarek, Michael Lam, Selvi Sert, Shawn N Whitehead, Ken K-C Yeung, Walter J Rushlow, Steven R Laviolett. Adolescent Δ-9-tetrahydrocannabinol exposure induces differential acute and long-term neuronal and molecular disturbances in dorsal vs. ventral hippocampal subregions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-19. PMID:36402837. |
in addition, using matrix-assisted laser desorption/ionization imaging mass spectrometry (maldi-ims), we show for the first time that adolescent thc exposure induces significant and enduring dysregulation of gaba and glutamate levels in dorsal vs. ventral hippocampus. |
2022-11-19 |
2023-08-14 |
Not clear |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
alteration of hippocampal egr3, gaba a receptors, il-1β, il6 and ccl3 expression in audiogenic tremor mice after seizure. |
2022-11-10 |
2023-08-14 |
mouse |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
therefore, we aimed to evaluate mrna expression levels of proinflammatory cytokines, early growth response factor 3 (egr3), and gaba a receptors in the hippocampus of naive audiogenic mutant tremor mice, and stimulated tremor mice after a seizure. |
2022-11-10 |
2023-08-14 |
mouse |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
il-1β may be involved in hippocampal downregulation of gaba a receptors of naive tremor mice, characterizing an important mechanism in audiogenic seizures triggering. |
2022-11-10 |
2023-08-14 |
mouse |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
hippocampal alterations of proinflammatory cytokines, egr3, and gaba a receptors in tremor mice reinforce them as an alternative tool to modeling temporal lobe epilepsy. |
2022-11-10 |
2023-08-14 |
mouse |
| Aleksandra Wisłowska-Stanek, Małgorzata Lehner, Filip Tomczuk, Karolina Kołosowska, Paweł Krząśnik, Danuta Turzyńska, Anna Skórzewsk. The role of the dorsal hippocampus in resistance to the development of posttraumatic stress disorder-like behaviours. Behavioural brain research. 2022-11-05. PMID:36334781. |
this study may suggest that the increase in gaba signalling in the hippocampus attenuates the activity of the crf system and enhances the function of the orexin system. |
2022-11-05 |
2023-08-14 |
rat |
| Chiye Aoki, Adrienne N Santiag. Pathway-specific GABAergic inhibition contributes to the gain of resilience against anorexia-like behavior of adolescent female mice. Frontiers in behavioral neuroscience. vol 16. 2022-10-31. PMID:36311865. |
we also include new data on the contribution to aba vulnerability by cell type-specific knockdown of a gaba receptor subunit, α4, in dorsal hippocampus. |
2022-10-31 |
2023-08-14 |
mouse |
| Elisa Landucci, Rolando Berlinguer-Palmini, Gilda Baccini, Francesca Boscia, Elisabetta Gerace, Guido Mannaioni, Domenico E Pellegrini-Giampietr. The Neuroprotective Effects of mGlu1 Receptor Antagonists Are Mediated by an Enhancement of GABAergic Synaptic Transmission via a Presynaptic CB1 Receptor Mechanism. Cells. vol 11. issue 19. 2022-10-14. PMID:36230976. |
in this study, we investigated the cross-talk between mglu1 and cb1 receptors in modulating gaba hippocampal output in whole-cell voltage clamp recordings in rat hippocampal acute slices, in organotypic hippocampal slices exposed to oxygen and glucose deprivation (ogd) and in gerbils subjected to global ischemia. |
2022-10-14 |
2023-08-14 |
rat |
| Elisa Landucci, Rolando Berlinguer-Palmini, Gilda Baccini, Francesca Boscia, Elisabetta Gerace, Guido Mannaioni, Domenico E Pellegrini-Giampietr. The Neuroprotective Effects of mGlu1 Receptor Antagonists Are Mediated by an Enhancement of GABAergic Synaptic Transmission via a Presynaptic CB1 Receptor Mechanism. Cells. vol 11. issue 19. 2022-10-14. PMID:36230976. |
our results show that mglu1 receptor antagonists enhance sipscs in ca1 pyramidal cells and the basal and ischemic hippocampal release of gaba in vivo in a manner that is mediated by cb1 receptor activation. |
2022-10-14 |
2023-08-14 |
rat |
| Eva Baranovicova, Dagmar Kalenska, Maria Kovalska, Jan Lehotsk. Hippocampal metabolic recovery as a manifestation of the protective effect of ischemic preconditioning in rats. Neurochemistry international. 2022-09-16. PMID:36113578. |
hippocampal tissues were characterized by postischemically decreased glutamate and gaba (4-aminobutyrate) tissue content balanced with increased glutamine level, with most pronounced changes at 3h reperfusion time. |
2022-09-16 |
2023-08-14 |
rat |
| Alexander Beletskiy, Ekaterina Positselskaya, Aliya Kh Vinarskaya, Yulia S Spivak, Yulia V Dobryakova, Iliya Tyulenev, Vladimir A Markevich, Alexey P Bolshako. Detailed Analysis of Dorsal-Ventral Gradients of Gene Expression in the Hippocampus of Adult Rats. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077346. |
our data suggest that the dorsal and ventral parts of the hippocampus differ in the expression of genes related to signaling pathways mediated by classical neurotransmitters (glutamate, gaba, monoamines, etc.) |
2022-09-09 |
2023-08-14 |
rat |