| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiaojiao Wang, Abolfazl Akbari, Marjan Chardahcherik, Jun W. Ginger (Zingiber Officinale Roscoe) ameliorates ethanol-induced cognitive impairment by modulating NMDA and GABA-A receptors in rat hippocampus. Metabolic brain disease. 2023-11-15. PMID:37966694. |
the aim of this study was to investigate the effects of ginger powder on ethanol-induced cognitive disorders by examining oxidative damage and inflammation status, and the gene expression of n-methyl-d-aspartate (nmda) and γ-aminobutyric acid (gaba)-a receptors in the hippocampus of male rats. |
2023-11-15 |
2023-11-20 |
rat |
| Yi Guo, Yuxin Kang, Wenjie Bai, Qiling Liu, Rongqiang Zhang, Yuxin Wang, Chong Wan. Perinatal exposure to bisphenol A impairs cognitive function via the gamma-aminobutyric acid signaling pathway in male rat offspring. Environmental toxicology. 2023-11-06. PMID:37926988. |
the research demonstrated that bpa exposure impacted the behavior and memory of male rat offspring and elevated the expression of glutamic acid decarboxylase 67 (gad67), gaba type a receptors subunit (gabaarα1), and gaba vesicle transporter (vgat) in the hippocampus while decreasing the expression levels of gaba transaminase (gaba-t) and gaba transporter 1 (gat-1). |
2023-11-06 |
2023-11-08 |
rat |
| Nikita Zernov, Elena Popugaev. Role of Neuronal TRPC6 Channels in Synapse Development, Memory Formation and Animal Behavior. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37895105. |
trpc6 is mainly expressed in the hippocampus, particularly in the dentate granule cells, cornu ammonis 3 (ca3) pyramidal cells and gamma-aminobutyric acid (gaba)ergic interneurons. |
2023-10-30 |
2023-11-08 |
Not clear |
| Hao Zhang, Mingqi Qiao, Dongmei Gao, Jieqiong Wang, Chunyan Sun, Ya Sun, Yang Zhang, Huayuan Liu, Zhen Zhang, Mingzhou Ga. Shuyu capsule alleviates premenstrual depression via allopregnanolone metabolic pathway targeting GABA (A) receptors δ subunit in the hippocampus. Asian journal of psychiatry. vol 90. 2023-10-28. PMID:37898099. |
shuyu capsule alleviates premenstrual depression via allopregnanolone metabolic pathway targeting gaba (a) receptors δ subunit in the hippocampus. |
2023-10-28 |
2023-11-08 |
rat |
| C Silva-Almeida, S C A Muniz, C M N Jobim, R Laureano-Melo, R S Lau, C R M Costa, W S Côrtes, D C Malvar, L C Reis, A S Mecawi, F F Roch. Perinatal environmental enrichment changes anxiety-like behaviours in mice and produces similar intergenerational benefits in offspring. Behavioural brain research. 2023-10-06. PMID:37802391. |
the frontal cortex and ventral hippocampus of pee mice were collected for the evaluation of the expression of gamma-aminobutyric acid (gaba)-related genes. |
2023-10-06 |
2023-10-15 |
mouse |
| Hany H Arab, Ahmed H Eid, Rania Yahia, Shuruq E Alsufyani, Ahmed M Ashour, Azza A K El-Sheikh, Hany W Darwish, Muhammed A Saad, Muhammad Y Al-Shorbagy, Marwa A Masou. Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats. Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765022. |
notably, it significantly diminished hippocampal glutamate content and enhanced acetylcholine and gaba neurotransmitters. |
2023-09-28 |
2023-10-07 |
rat |
| Yue Pan, Qinglan Zong, Guoxiang Li, Zhengcun Wu, Tingfu Du, Ying Zhang, Zhangqiong Huang, Kaili M. Nuclear localization of alpha-synuclein induces anxiety-like behavior in mice by decreasing hippocampal neurogenesis and pathologically affecting amygdala circuits. Neuroscience letters. 2023-09-24. PMID:37742940. |
our results show that α-syn overexpression in the nuclei increased the excitability of hippocampal neurons and activated ng2 glial cells and promoted the synthesis and release of γ-aminobutyric acid (gaba). |
2023-09-24 |
2023-10-07 |
mouse |
| Cristina Torres-López, Maria I Cuartero, Alicia García-Culebras, Juan de la Parra, María E Fernández-Valle, Marina Benito, Sandra Vázquez-Reyes, Tania Jareño-Flores, Francisco J de Castro-Millán, Olivia Hurtado, Marion S Buckwalter, Juan M García-Segura, Ignacio Lizasoain, María A Mor. Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in Mice. Stroke. 2023-09-11. PMID:37694402. |
ipsilesional hippocampal gaba is elevated and correlates with cognitive impairment and maladaptive neurogenesis after cortical stroke in mice. |
2023-09-11 |
2023-10-07 |
mouse |
| Andreia Amaro, Diana Sousa, Mariana Sá-Rocha, Marcos Divino Ferreira-Junior, Daniela Rosendo-Silva, Lucas Paulo Jacinto Saavedra, Cátia Barra, Tamaeh Monteiro-Alfredo, Rodrigo Mello Gomes, Paulo Cezar de Freitas Mathias, Filipa I Baptista, Paulo Matafom. Postnatal Overfeeding in Rodents Induces a Neurodevelopment Delay and Anxious-like Behaviour Accompanied by Sex- and Brain-Region-Specific Synaptic and Metabolic Changes. Nutrients. vol 15. issue 16. 2023-08-26. PMID:37630771. |
furthermore, both sexes presented synaptic changes in the hippocampus (lower gaba |
2023-08-26 |
2023-09-07 |
Not clear |
| Hany H Arab, Ahmed H Eid, Shuruq E Alsufyani, Ahmed M Ashour, Azza A K El-Sheikh, Hany W Darwish, Gehan S Georg. Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy. Pharmaceuticals (Basel, Switzerland). vol 16. issue 8. 2023-08-26. PMID:37630980. |
meanwhile, it enhanced hippocampal acetylcholine and gaba and diminished the glutamate spike. |
2023-08-26 |
2023-09-07 |
rat |
| Sahel Motaghi, Mahya Moradi Sirchi, Narge Sadat Hosseininasab, Mehdi Abbasnejad, Saeed Esmaili-Mahani, Gholamreza Sepehr. Age-Related Changes in Glutamic Acid Decarboxylase 1 Gene Expression in the Medial Prefrontal Cortex and Ventral Hippocampus of Fear-Potentiated Rats Subjected to Isolation Stress. Behavioural brain research. 2023-08-16. PMID:37586565. |
gamma-aminobutyric acid (gaba) plays a crucial role as a neurotransmitter in anxiety circuits, prominently in the hippocampus, amygdala, and prefrontal cortex. |
2023-08-16 |
2023-09-07 |
rat |
| Anthony Ariza, Setareh Malekian Naeini, Shahin Khodaei, Joycelyn Ba, Dian-Shi Wang, Beverley Anne Orse. Cell-surface biotinylation of GABA STAR protocols. vol 4. issue 3. 2023-07-22. PMID:37480561. |
cell-surface biotinylation of gaba here, we present a protocol for studying the cell-surface proteins in hippocampal slices after in vivo administration of sevoflurane, an inhaled general anesthetic drug, to mice. |
2023-07-22 |
2023-08-14 |
mouse |
| Lingxue Meng, Shiheng Gui, Zedong Ouyang, Yajuan Wu, Youling Zhuang, Qihua Pang, Ruifang Fa. Low-dose bisphenols exposure sex-specifically induces neurodevelopmental toxicity in juvenile rats and the antagonism of EGCG. Journal of hazardous materials. vol 459. 2023-07-20. PMID:37473573. |
in in vitro experiments, primary hippocampal neurons from neonatal rats of different genders were treated with bisphenol a (bpa), bisphenol s (bps) and bisphenol b (bpb) at 1 nm-100 μm, epigallocatechin gallate (egcg) and g15, an antagonist of g protein-coupled estrogen receptor (gper) for 7 d. results indicated that bps affected neuronal morphogenesis, impaired gaba synthesis and glu/gaba homeostasis. |
2023-07-20 |
2023-08-14 |
rat |
| Arzuhan Cetindag Ciltas, Cemal Erdem Toy, Handan Güneş, Meryem Yapra. Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats. Epilepsy research. vol 195. 2023-07-20. PMID:37473590. |
this research investigated the impacts of probiotic mixture on epileptic seizures, gamma aminobutyric acid (gaba), glutamate, and tas and tos levels in hippocampal tissue in the ptz-induced acute seizure model in rats. |
2023-07-20 |
2023-08-14 |
rat |
| C Peerboom, S De Kater, N Jonker, M P J M Rieter, T Wijne, C J Wiereng. Delaying the GABA shift indirectly affects membrane properties in the developing hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-12. PMID:37438107. |
delaying the gaba shift indirectly affects membrane properties in the developing hippocampus. |
2023-07-12 |
2023-08-14 |
mouse |
| C Peerboom, S De Kater, N Jonker, M P J M Rieter, T Wijne, C J Wiereng. Delaying the GABA shift indirectly affects membrane properties in the developing hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-12. PMID:37438107. |
here we examine the direct and indirect consequences of a delayed postnatal gaba shift on network development in organotypic hippocampal cultures made from 6 to 7-day old mice by treating the cultures for one week with vu0463271, a specific inhibitor of the chloride exporter kcc2. |
2023-07-12 |
2023-08-14 |
mouse |
| Huiwen Kang, Wei Zhang, Jiaru Jing, Danyang Huang, Lei Zhang, Jingyu Wang, Lin Han, Ziyan Liu, Ziyan Wang, Ai Ga. The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways. Journal of hazardous materials. vol 458. 2023-07-01. PMID:37392641. |
we found that 80 nm ps-nps could reach and cause neuronal damage in the hippocampus, and alter the expression of neuroplasticity-related molecules (5-ht, ache, gaba, bdnf and creb), and even affect the learning and memory ability of mice. |
2023-07-01 |
2023-08-14 |
mouse |
| Kenta Deriha, Eri Hashimoto, Wataru Ukai, Francesca Marchisella, Emi Nishimura, Hanako Hashiguchi, Masaya Tayama, Takao Ishii, Marco A Riva, Chiaki Kawanish. Reduced sociability in a prenatal immune activation model: Modulation by a chronic blonanserin treatment through the amygdala-hippocampal axis. Journal of psychiatric research. vol 164. 2023-06-28. PMID:37379611. |
low dose of blonanserin and haloperidol altered gaba and glutamate-related mrna levels, the e/i ratio, and bdnf long 3'utr mrna levels in the ventral hippocampus and amygdala, but did not attenuate behavioral impairments. |
2023-06-28 |
2023-08-14 |
rat |
| Jiaxin Zheng, Sisi Peng, Lingling Cui, Xi Liu, Tian Li, Zhenyu Zhao, Yaqing Li, Yuan Hu, Miao Zhang, Linling Xu, JunJian Zhan. Enriched environment attenuates hippocampal theta and gamma rhythms dysfunction in chronic cerebral hypoperfusion via improving imbalanced neural afferent levels. Frontiers in cellular neuroscience. vol 17. 2023-06-02. PMID:37265581. |
the results showed that ee significantly improved the balance of three classical neurotransmitters (acetylcholine, glutamate, and gaba) in the hippocampus, enhanced the strength of theta and slow-gamma (sg) rhythms, and dramatically improved neural coupling across frequency bands in cch rats. |
2023-06-02 |
2023-08-14 |
rat |
| Caroline Lahogue, Jean-Marie Billard, Thomas Freret, Valentine Boue. 5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238621. |
5-ht6 receptors sex-dependently modulate hippocampal synaptic activity through gaba inhibition. |
2023-05-27 |
2023-08-14 |
mouse |