| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pezhman Atefimanash, Mahsa Pourhamzeh, Alireza Susanabadi, Mehrnoosh Arabi, Nida Jamali-Raeufy, Soraya Mehrab. Hippocampal chloride transporter KCC2 contributes to excitatory GABA dysregulation in the developmental rat model of schizophrenia. Journal of chemical neuroanatomy. vol 118. 2021-12-07. PMID:34695562. |
hippocampal chloride transporter kcc2 contributes to excitatory gaba dysregulation in the developmental rat model of schizophrenia. |
2021-12-07 |
2023-08-13 |
rat |
| Pezhman Atefimanash, Mahsa Pourhamzeh, Alireza Susanabadi, Mehrnoosh Arabi, Nida Jamali-Raeufy, Soraya Mehrab. Hippocampal chloride transporter KCC2 contributes to excitatory GABA dysregulation in the developmental rat model of schizophrenia. Journal of chemical neuroanatomy. vol 118. 2021-12-07. PMID:34695562. |
our findings show that isolation rearing reduces hippocampal kcc2 expression level and may underlie hippocampal gaba excitatory. |
2021-12-07 |
2023-08-13 |
rat |
| Pezhman Atefimanash, Mahsa Pourhamzeh, Alireza Susanabadi, Mehrnoosh Arabi, Nida Jamali-Raeufy, Soraya Mehrab. Hippocampal chloride transporter KCC2 contributes to excitatory GABA dysregulation in the developmental rat model of schizophrenia. Journal of chemical neuroanatomy. vol 118. 2021-12-07. PMID:34695562. |
collectively, our findings show that hippocampal chloride transporter kcc2 contributes to excitatory gaba dysregulation in the developmental rat model of schizophrenia. |
2021-12-07 |
2023-08-13 |
rat |
| Barna Dudok, Miklos Szoboszlay, Anirban Paul, Peter M Klein, Zhenrui Liao, Ernie Hwaun, Gergely G Szabo, Tristan Geiller, Bert Vancura, Bor-Shuen Wang, Sam McKenzie, Jesslyn Homidan, Lianne M F Klaver, Daniel F English, Z Josh Huang, György Buzsáki, Attila Losonczy, Ivan Soltes. Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior. Neuron. vol 109. issue 23. 2021-12-05. PMID:34648750. |
bidirectional intervention experiments in head-restrained mice performing a random foraging task revealed that aacs inhibit ca1 pyramidal cells, indicating that the effect of gaba on the initial segments in the hippocampus is inhibitory in vivo. |
2021-12-05 |
2023-08-13 |
mouse |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
in addition, semen sojae praeparatum significantly promoted the contents of norepinephrine (ne), 5-hydroxytryptamine (5-ht), brain-derived neurotrophic factor (bdnf), and gamma-aminobutyric acid (gaba) in the hippocampus and the content of bdnf in the serum (p < 0.05). |
2021-12-05 |
2023-08-13 |
rat |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.). vol 150. issue Pt B. 2021-12-05. PMID:34863499. |
genus ruminococcaceae_ucg-008 was positively correlated with gaba and bdnf levels in the hippocampus; genus lactobacillus had a positive correlation with 5-ht; and genus bacteroides had negative correlations with 5-ht, bdnf, and ne. |
2021-12-05 |
2023-08-13 |
rat |
| Julie K Staples, Courtney Gibson, Madeline Udd. Complementary and Integrative Health Interventions for Insomnia in Veterans and Military Populations. Psychological reports. 2021-12-02. PMID:34855539. |
it also proposes possible mechanisms by which cih practices may be effective, including increasing hippocampal volume and gamma-aminobutyric acid acid (gaba). |
2021-12-02 |
2023-08-13 |
Not clear |
| Yuya Sakimoto, Paw Min-Thein Oo, Makoto Goshima, Itsuki Kanehisa, Yutaro Tsukada, Dai Mitsushim. Significance of GABA International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830337. |
significance of gaba the hippocampus is a primary area for contextual memory, known to process spatiotemporal information within a specific episode. |
2021-11-30 |
2023-08-13 |
Not clear |
| Miriam Gwilt, Markus Bauer, Tobias Bas. Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anesthetized rats. Hippocampus. vol 30. issue 10. 2021-11-26. PMID:32396678. |
we predicted frequency-specific lfp changes, based on previous studies implicating gaba in hippocampal oscillations, with the weight of evidence suggesting that disinhibition would facilitate theta and disrupt gamma oscillations. |
2021-11-26 |
2023-08-13 |
rat |
| Sahel Motaghi, Hadi Moghaddam Dizaj Herik, Gholamreza Sepehri, Mehdi Abbasnejad, Saeed Esmaeli-Mahan. The anxiolytic effect of salicylic acid is mediated via the GABAergic system in the fear potentiated plus maze behavior in rats. Molecular biology reports. 2021-11-19. PMID:34797490. |
in this study, by using the fear potentiated plus maze test, we evaluated the effect of salicylic acid on the gene expression of the main form of gaba (gamma aminobutyric acid) synthesizing enzyme i.e., the enzyme glutamic acid decarboxylase 67 (gad67) which is called gad1, in the ventral subiculum of the hippocampus, one of the main brain structures, in anxiety circuits. |
2021-11-19 |
2023-08-13 |
rat |
| Jürgen Graf, Chuanqiang Zhang, Stephan Lawrence Marguet, Tanja Herrmann, Tom Flossmann, Robin Hinsch, Vahid Rahmati, Madlen Guenther, Christiane Frahm, Anja Urbach, Ricardo Melo Neves, Otto W Witte, Stefan J Kiebel, Dirk Isbrandt, Christian A Hübner, Knut Holthoff, Knut Kirms. A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 14. 2021-11-18. PMID:33782119. |
we report that nkcc1 deletion from telencephalic glutamatergic neurons decreases in vitro excitatory actions of γ-aminobutyric acid (gaba) and impairs neuronal synchrony in neonatal hippocampal brain slices. |
2021-11-18 |
2023-08-13 |
mouse |
| Alexander G Figueroa, Claudia Benkwitz, Gabe Surges, Nicholas Kunz, Gregg E Homanics, Robert A Pearc. Hippocampal β2-GABA Journal of neurophysiology. vol 126. issue 4. 2021-11-17. PMID:34406874. |
hippocampal β2-gaba the general anesthetic etomidate, which acts through γ-aminobutyric acid type a (gaba |
2021-11-17 |
2023-08-13 |
Not clear |
| Kristin Metzdorf, Steffen Fricke, Maria Teresa Balia, Martin Korte, Marta Zagrebelsk. Nogo-A Modulates the Synaptic Excitation of Hippocampal Neurons in a Ca Cells. vol 10. issue 9. 2021-11-17. PMID:34571950. |
we show that nogo-a loss-of-function in primary mouse hippocampal cultures by application of a function-blocking antibody leads to higher excitation following a decrease in gaba |
2021-11-17 |
2023-08-13 |
mouse |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
on this basis, gaba content in the drn and 5-ht contents in the pfc, hypothalamus, hippocampus and drn were detected using elisa. |
2021-11-11 |
2023-08-13 |
rat |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
the contents of 5-ht in the pfc, hypothalamus and hippocampus of rats with high and low aggressive behavior (no difference between the two groups) were significantly decreased, but the change in gaba content in the drn was the opposite. |
2021-11-11 |
2023-08-13 |
rat |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
the significant increase in gaba in the drn combined with the significant increase in gb1 in the drn further mediated the synaptic inhibition effect, which reduced the 5-ht level of 5-ht neurons in the drn, resulting in a significant decrease in 5-ht levels in the pfc, hypothalamus and hippocampus. |
2021-11-11 |
2023-08-13 |
rat |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
therefore, gb1-mediated gaba regulation of 5-ht levels in the pfc, hypothalamus and hippocampus is one of the mechanisms of highly and less aggressive behavior originating in the drn. |
2021-11-11 |
2023-08-13 |
rat |
| Amanda Kiemes, Felipe V Gomes, Diana Cash, Daniela L Uliana, Camilla Simmons, Nisha Singh, Anthony C Vernon, Federico Turkheimer, Cathy Davies, James M Stone, Anthony A Grace, Gemma Modino. GABA Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-07. PMID:34743200. |
gaba hippocampal hyperactivity driven by gabaergic interneuron deficits and nmda receptor hypofunction is associated with the hyperdopaminergic state often observed in schizophrenia. |
2021-11-07 |
2023-08-13 |
rat |
| Amanda Kiemes, Felipe V Gomes, Diana Cash, Daniela L Uliana, Camilla Simmons, Nisha Singh, Anthony C Vernon, Federico Turkheimer, Cathy Davies, James M Stone, Anthony A Grace, Gemma Modino. GABA Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-07. PMID:34743200. |
here, we sought to characterize hippocampal gaba |
2021-11-07 |
2023-08-13 |
rat |
| Jayarjun Ethiraj, Thulani Hansika Palpagama, Clinton Turner, Bert van der Werf, Henry John Waldvogel, Richard Lewis Maxwell Faull, Andrea Kwakowsk. The effect of age and sex on the expression of GABA signaling components in the human hippocampus and entorhinal cortex. Scientific reports. vol 11. issue 1. 2021-11-06. PMID:34728681. |
the effect of age and sex on the expression of gaba signaling components in the human hippocampus and entorhinal cortex. |
2021-11-06 |
2023-08-13 |
human |