| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Fernández-Espejo, L Núñez-Domíngue. Endocannabinoid-mediated synaptic plasticity and substance use disorders. Neurologia (Barcelona, Spain). 2021-09-20. PMID:34538595. |
in the short term, we may stress "inhibitory" phenomena, such as depolarisation-induced suppression of inhibition and depolarisation-induced suppression of excitation, and such "disinhibitory" phenomena as long-lasting disinhibition of neuronal activity, particularly in the striatum, and suppression of hippocampal gaba release. |
2021-09-20 |
2023-08-13 |
Not clear |
| Yannik Völzke, Eberhard D Pracht, Elke Hattingen, Desmond H Y Tse, Tony Stöcke. On the reproducibility of hippocampal MEGA-sLASER GABA MRS at 7T using an optimized analysis pipeline. Magma (New York, N.Y.). vol 34. issue 3. 2021-09-16. PMID:32865653. |
on the reproducibility of hippocampal mega-slaser gaba mrs at 7t using an optimized analysis pipeline. |
2021-09-16 |
2023-08-13 |
Not clear |
| Mahesh Bekal, Lue Sun, Susumu Ueno, Takashi Moritak. Neurobehavioral effects of acute low-dose whole-body irradiation. Journal of radiation research. vol 62. issue 5. 2021-09-16. PMID:33982114. |
a serotonin (5-ht), dopamine, gamma-aminobutyric acid (gaba) and cortisol analysis was carried out in blood, hippocampus, amygdala and whole brain tissue. |
2021-09-16 |
2023-08-13 |
mouse |
| Ryo Inotsuka, Miyako Udono, Atsushi Yamatsu, Mujo Kim, Yoshinori Katakur. Exosome-Mediated Activation of Neuronal Cells Triggered by γ-Aminobutyric Acid (GABA). Nutrients. vol 13. issue 8. 2021-09-15. PMID:34444704. |
finally, we performed a microarray analysis of mrna isolated from the hippocampus of mice that were orally administered gaba. |
2021-09-15 |
2023-08-13 |
mouse |
| Ryo Inotsuka, Miyako Udono, Atsushi Yamatsu, Mujo Kim, Yoshinori Katakur. Exosome-Mediated Activation of Neuronal Cells Triggered by γ-Aminobutyric Acid (GABA). Nutrients. vol 13. issue 8. 2021-09-15. PMID:34444704. |
gene set enrichment analysis (gsea) showed that oral administration of gaba affected the expression of genes related to memory function in the hippocampus. |
2021-09-15 |
2023-08-13 |
mouse |
| Juan Li, Luting Chen, Feng Guo, Xiaohua Ha. The Effects of GABAergic System under Cerebral Ischemia: Spotlight on Cognitive Function. Neural plasticity. vol 2020. 2021-09-13. PMID:33061952. |
we present a review of the changes of the gabaergic system in the hippocampus under ischemia, including gaba interneurons, extracellular gaba neurotransmitter, and gaba receptors. |
2021-09-13 |
2023-08-13 |
Not clear |
| Alaa Alachkar, Mohamed Lotfy, Ernest Adeghate, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sade. Ameliorating effects of histamine H3 receptor antagonist E177 on acute pentylenetetrazole-induced memory impairments in rats. Behavioural brain research. vol 405. 2021-09-02. PMID:33626390. |
moreover, and in the hippocampus of ptz-treated animals, e177 mitigated abnormal levels of ache activity, ach and ha (all p < 0.05), but failed to modify brain levels of gaba and glu. |
2021-09-02 |
2023-08-13 |
rat |
| Olha Zapukhliak, Olga Netsyk, Artur Romanov, Oleksandr Maximyuk, Murat Oz, Gregory L Holmes, Oleg Krishtal, Dmytro Isae. Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors. PloS one. vol 16. issue 3. 2021-08-31. PMID:33711021. |
in this work, we studied the ability of the cholinergic system to sustain hippocampal epileptiform activity independently from glutamate and gaba transmission. |
2021-08-31 |
2023-08-13 |
Not clear |
| Olha Zapukhliak, Olga Netsyk, Artur Romanov, Oleksandr Maximyuk, Murat Oz, Gregory L Holmes, Oleg Krishtal, Dmytro Isae. Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors. PloS one. vol 16. issue 3. 2021-08-31. PMID:33711021. |
simultaneous ca3 and ca1 field potential recordings were obtained during the perfusion of hippocampal slices with the acsf containing ampa, nmda and gaba receptor antagonists. |
2021-08-31 |
2023-08-13 |
Not clear |
| Joan Jiménez-Balado, Teal S Eic. GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer's disease. Seminars in cell & developmental biology. vol 116. 2021-08-23. PMID:33573856. |
well-established animal models have shown that gaba plays a central role in regulating and synchronizing neuronal signaling in the hippocampus, a brain area critical for episodic memory that undergoes early and significant morphologic and functional changes in the course of ad. |
2021-08-23 |
2023-08-13 |
human |
| Gollapalle Lakshminarayanashastry Viswanatha, Hanumanthappa Shylaja, Darisi Venkata Kishore, Marikunte V Venkataranganna, Nunna Bheema Lingeswara Prasa. Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways. Neurotoxicity research. vol 38. issue 4. 2021-08-20. PMID:32803629. |
therefore, further mechanism-based studies were performed on the ptz model, and the outcomes have revealed that there was a significant reduction in gaba (p < 0.01 for both regions) and elevation of glutamate (p < 0.01 for both regions) in the cortex and hippocampus regions of ptz-treated animals. |
2021-08-20 |
2023-08-13 |
mouse |
| Hayma Hammoud, Olga Netsyk, Atieh S Tafreshiha, Sergiy V Korol, Zhe Jin, Jin-Ping Li, Bryndis Birni. Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease. Acta physiologica (Oxford, England). vol 232. issue 2. 2021-08-18. PMID:33559388. |
insulin differentially modulates gaba signalling in hippocampal neurons and, in an age-dependent manner, normalizes gaba-activated currents in the tg-appswe mouse model of alzheimer's disease. |
2021-08-18 |
2023-08-13 |
mouse |
| Hayma Hammoud, Olga Netsyk, Atieh S Tafreshiha, Sergiy V Korol, Zhe Jin, Jin-Ping Li, Bryndis Birni. Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease. Acta physiologica (Oxford, England). vol 232. issue 2. 2021-08-18. PMID:33559388. |
we examined if tonic γ-aminobutyric acid (gaba)-activated currents in primary hippocampal neurons were modulated by insulin in wild-type and tg-appswe mice, an alzheimer's disease (ad) model. |
2021-08-18 |
2023-08-13 |
mouse |
| Manana G Dashniani, Maia A Burjanadze, Nino C Chkhikvishvili, Revaz O Solomonia, Manana Kandashvili, Temur L Naneishvili, Gela V Beselia, Lali B Kruashvili, Mariam R Chighladz. Modulation of spatial memory and expression of hippocampal neurotransmitter receptors by selective lesion of medial septal cholinergic and GABAergic neurons. Experimental brain research. vol 238. issue 10. 2021-07-28. PMID:32770352. |
these results for the first time demonstrated that selective lesions of ms cholinergic and gabaergic neurons differentially affect long-term spatial memory and the memory deficit after ms gabaergic lesion is paralleled with significant changes of hippocampal glutamate, gaba and acetylcholine receptors expression. |
2021-07-28 |
2023-08-13 |
rat |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
protein expression levels of the gaba synthesis enzyme glutamate decarboxylase (gad) gad67 were decreased in the ventral hippocampus as well. |
2021-07-16 |
2023-08-13 |
mouse |
| Olivier Dubanet, Arnaldo Ferreira Gomes Da Silva, Andreas Frick, Hajime Hirase, Anna Beyeler, Xavier Leinekuge. Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo. Cell reports. vol 36. issue 2. 2021-07-14. PMID:34260906. |
it represents a promising tool for the investigation of excitatory gaba in different pathological conditions that may affect the hippocampal circuit. |
2021-07-14 |
2023-08-13 |
mouse |
| Marcin Wyroślak, Katarzyna Lebida, Jerzy W Mozrzyma. Induction of Inhibitory Synaptic Plasticity Enhances Tonic Current by Increasing the Content of α5-Subunit Containing GABA Neuroscience. vol 467. 2021-07-12. PMID:34033868. |
induction of inhibitory synaptic plasticity enhances tonic current by increasing the content of α5-subunit containing gaba it is known that besides synaptic inhibition, there is a persistent component of inhibitory drive mediated by tonic currents which is believed to mediate majority of the total inhibitory charge in hippocampal neurons. |
2021-07-12 |
2023-08-13 |
Not clear |
| Alejandro Martín-Belmonte, Carolina Aguado, Rocío Alfaro-Ruíz, Ana Esther Moreno-Martínez, Luis de la Ossa, José Martínez-Hernández, Alain Buisson, Simon Früh, Bernhard Bettler, Ryuichi Shigemoto, Yugo Fukazawa, Rafael Lujá. Reduction in the neuronal surface of post and presynaptic GABA Brain pathology (Zurich, Switzerland). vol 30. issue 3. 2021-07-08. PMID:31729777. |
reduction in the neuronal surface of post and presynaptic gaba the hippocampus plays key roles in learning and memory and is a main target of alzheimer's disease (ad), which causes progressive memory impairments. |
2021-07-08 |
2023-08-13 |
Not clear |
| I Yu Teplov, V P Zinchenko, A M Kosenkov, S G Gaidin, M N Nenov, A I Sergee. Involvement of NMDA and GABA(A) receptors in modulation of spontaneous activity in hippocampal culture: Interrelations between burst firing and intracellular calcium signal. Biochemical and biophysical research communications. vol 553. 2021-07-06. PMID:33765560. |
involvement of nmda and gaba(a) receptors in modulation of spontaneous activity in hippocampal culture: interrelations between burst firing and intracellular calcium signal. |
2021-07-06 |
2023-08-13 |
Not clear |
| Makoto Shibutan. [Hippocampal neurogenesis as a critical target of developmental neurotoxicity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 156. issue 4. 2021-07-02. PMID:34193705. |
monitoring of granule cell lineages generated from the subgranular zone and γ-aminobutyric acid (gaba)-ergic interneurons in the hilus of the dentate gyrus as major players consisting of hippocampal neurogenesis is effective for detecting target cell populations of developmental neurotoxicants. |
2021-07-02 |
2023-08-13 |
Not clear |