| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariska van Lier, M Hadi Saiepour, Koen Kole, Juliette E Cheyne, Nawal Zabouri, Thomas Blok, Yi Qin, Emma Ruimschotel, J Alexander Heimel, Christian Lohmann, Christiaan N Level. Disruption of Critical Period Plasticity in a Mouse Model of Neurofibromatosis Type 1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 28. 2020-11-26. PMID:32527982. |
modulating the signaling pathways causing increased gaba release in a mouse model of nf1 reverts deficits in hippocampal learning. |
2020-11-26 |
2023-08-13 |
mouse |
| Siju Ellickal Narayanan, Nisha Abdul Rehuman, Seetha Harilal, Anju Vincent, Rajalakshmi Ganesan Rajamma, Tapan Behl, Md Sahab Uddin, Ghulam Md Ashraf, Bijo Mathe. Molecular mechanism of zinc neurotoxicity in Alzheimer's disease. Environmental science and pollution research international. vol 27. issue 35. 2020-11-25. PMID:32909132. |
zn also regulates excitatory and inhibitory neurotransmitters such as glutamate and gaba and is found in high concentration in the synaptic terminals of hippocampal mossy fibers that maintains cognitive function. |
2020-11-25 |
2023-08-13 |
human |
| Pampa Saha, Rajaneesh Gupta, Tanusree Sen, Nilkantha Se. Histone Deacetylase 4 Downregulation Elicits Post-Traumatic Psychiatric Disorders through Impairment of Neurogenesis. Journal of neurotrauma. vol 36. issue 23. 2020-11-09. PMID:31169064. |
here we have shown that an imbalance in the generation of γ-aminobutyric acid (gaba)ergic and glutamatergic neurons due to aberrant induction of vesicular glutamate transporter 1 (vglut1)-positive glutamatergic cells is responsible for impaired neuronal differentiation in the hippocampus following tbi. |
2020-11-09 |
2023-08-13 |
Not clear |
| Mª Dolores Muñoz, Nerea de la Fuente, Amelia Sánchez-Capel. TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. International journal of molecular sciences. vol 21. issue 2. 2020-11-02. PMID:31963327. |
γ-aminobutiryc acid (gaba) is found extensively in different brain nuclei, including parts involved in parkinson's disease (pd), such as the basal ganglia and hippocampus. |
2020-11-02 |
2023-08-13 |
Not clear |
| Isabel Carreras, Nurgul Aytan, Ji-Kyung Choi, Christina M Tognoni, Neil W Kowall, Bruce G Jenkins, Alpaslan Dedeogl. Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31358793. |
at 1 mg/kg/day, fingolimod decreased both peripheral blood lymphocyte counts and brain aβ levels, but at the lowest dose tested (0.03 mg/kg/day), we detected improved memory, decreased activation of brain microglia and astrocytes, and restored hippocampal levels of gaba and glycerophosphocholine with no effect on circulating lymphocyte counts. |
2020-10-27 |
2023-08-13 |
mouse |
| Batsheva R Rubin, Teresa A Milner, Virginia M Pickel, Christal G Coleman, Jose Marques-Lopes, Tracey A Van Kempen, Syed Faraz Kazim, Bruce S McEwen, Jason D Gray, Ana C Pereir. Sex and age differentially affect GABAergic neurons in the mouse prefrontal cortex and hippocampus following chronic intermittent hypoxia. Experimental neurology. vol 325. 2020-10-23. PMID:31837319. |
the sex- and age- specific effects of osa-associated cih on specific cell populations such as γ-aminobutyric acid (gaba)-ergic neurons in the hippocampus and the medial prefrontal cortex (mpfc), regions important for cognitive function, remain largely unknown. |
2020-10-23 |
2023-08-13 |
mouse |
| Tara G Chowdhury, Gauri S Wable, Yi-Wen Chen, Kei Tateyama, Irene Yu, Jia-Yi Wang, Alex D Reyes, Chiye Aok. Voluntary Wheel Running Exercise Evoked by Food-Restriction Stress Exacerbates Weight Loss of Adolescent Female Rats But Also Promotes Resilience by Enhancing GABAergic Inhibition of Pyramidal Neurons in the Dorsal Hippocampus. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30462186. |
in vitro slice physiology revealed doubling of pyramidal neurons' gaba response in the dorsal hippocampus of food-restricted animals with wheel access (fr + ex for 4 days), but without increase of mipsc amplitudes. |
2020-10-13 |
2023-08-13 |
rat |
| Hartmut T Bocker, Theresa Heinrich, Lutz Liebmann, J Christopher Hennings, Eric Seemann, Melanie Gerth, Igor Jakovčevski, Julia Preobraschenski, Michael M Kessels, Martin Westermann, Dirk Isbrandt, Reinhard Jahn, Britta Qualmann, Christian A Hübne. The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30541023. |
from our electrophysiological analyses in the ca1 of the hippocampus, we conclude that the disruption in parvalbumin-positive neurons impairs the release of gaba-loaded vesicles, but increases the size of gaba quanta. |
2020-10-13 |
2023-08-13 |
mouse |
| Gregers Wegener, Vallo Volk. Nitric Oxide Synthase Inhibitors as Antidepressants. Pharmaceuticals (Basel, Switzerland). vol 3. issue 1. 2020-10-01. PMID:27713253. |
moreover, several of the conventional neurotransmitters, including serotonin, glutamate and gaba, are intimately regulated by no, and distinct classes of antidepressants have been found to modulate the hippocampal no level in vivo. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jennifer Larimore, Stephanie A Zlatic, Miranda Arnold, Kaela S Singleton, Rebecca Cross, Hannah Rudolph, Martha V Bruegge, Andrea Sweetman, Cecilia Garza, Eli Whisnant, Victor Faunde. Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Frontiers in genetics. vol 8. 2020-10-01. PMID:28344592. |
dysbindin deficiency modifies the expression of gaba neuron and ion permeation transcripts in the developing hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Ilgam Khalilov, Marat Minlebaev, Marat Mukhtarov, Elvira Juzekaeva, Roustem Khazipo. Postsynaptic GABA(B) Receptors Contribute to the Termination of Giant Depolarizing Potentials in CA3 Neonatal Rat Hippocampus. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28701925. |
postsynaptic gaba(b) receptors contribute to the termination of giant depolarizing potentials in ca3 neonatal rat hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Kyle J Brymer, Erin Y Fenton, Lisa E Kalynchuk, Hector J Carunch. Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABA Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29515447. |
peripheral etanercept administration normalizes behavior, hippocampal neurogenesis, and hippocampal reelin and gaba depression is a serious psychiatric disorder frequently comorbid with autoimmune disorders. |
2020-10-01 |
2023-08-13 |
rat |
| Kyle J Brymer, Erin Y Fenton, Lisa E Kalynchuk, Hector J Carunch. Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABA Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29515447. |
to test this hypothesis, we examined the effect of repeated cort injections and concurrent injections of etanercept on measures of object-location and object-in-place memory, forced-swim test behavior, hippocampal neurogenesis, and reelin and gaba β2/3 immunohistochemistry. |
2020-10-01 |
2023-08-13 |
rat |
| Heejung Chun, Heeyoung An, Jiwoon Lim, Junsung Woo, Jaekwang Lee, Hoon Ryu, C Justin Le. Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus. Experimental neurobiology. vol 27. issue 3. 2020-10-01. PMID:30022867. |
astrocytic probdnf and tonic gaba distinguish active versus reactive astrocytes in hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Heejung Chun, Heeyoung An, Jiwoon Lim, Junsung Woo, Jaekwang Lee, Hoon Ryu, C Justin Le. Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus. Experimental neurobiology. vol 27. issue 3. 2020-10-01. PMID:30022867. |
strikingly, a stab wound brain injury lead to hypertrophy of astrocytes accompanied by increased gaba expression and tonic gaba release in mouse ca1 hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| JinHong Jiang, YaLi Peng, XueYa Liang, Shu Li, Xin Chang, LongFei Li, Min Chan. Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via Mediating Ghrelin and GABA Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30072893. |
centrally administered cortistation-14 induces antidepressant-like effects in mice via mediating ghrelin and gaba cortistatin-14 (cst-14), a recently discovered cyclic neuropeptide, can bind to all five cloned somatostatin receptors (sstrs) and ghrelin receptor to exert its biological activities and co-exists with gaba within the cortex and hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Xiangchang Zeng, Kai Hu, Lulu Chen, Luping Zhou, Wei Luo, Chaopeng Li, Wenjing Zong, Siyu Chen, Qing Gao, Guirong Zeng, Dejian Jiang, Xiaohui Li, Honghao Zhou, Dong-Sheng Ouyan. The Effects of Ginsenoside Compound K Against Epilepsy by Enhancing the γ-Aminobutyric Acid Signaling Pathway. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30254585. |
previous studies show that gck promoted the release of gaba from the hippocampal neurons and enhanced the activity of gaba |
2020-10-01 |
2023-08-13 |
Not clear |
| Junxiu Liu, Liam McDaid, Alfonso Araque, John Wade, Jim Harkin, Shvan Karim, David C Henshall, Niamh M C Connolly, Anju P Johnson, Andy M Tyrrell, Jon Timmis, Alan G Millard, James Hilder, David M Hallida. GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31396055. |
gaba regulation of burst firing in hippocampal astrocyte neural circuit: a biophysical model. |
2020-10-01 |
2023-08-13 |
Not clear |
| Miguel Ángel Pérez, Camila Morales, Odra Santander, Francisca García, Isabel Gómez, Valentín Peñaloza-Sancho, Pablo Fuentealba, Alexies Dagnino-Subiabre, Pablo R Moya, Marco Fuenzalid. Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31481877. |
several findings suggest that these impairments are related to a dysfunction in γ-aminobutyric acid (gaba) neurotransmission in brain areas such as the medial prefrontal cortex (mpfc), the hippocampus (hpc) and the primary auditory cortex (a1); however, it is still unclear how the gabaergic system is disrupted in these brain areas. |
2020-10-01 |
2023-08-13 |
rat |
| Li-Li Tu, Qin Sun, Ling-Ling Wei, Jing Shi, Jian-Ping L. Upregulation of GABA receptor promotes long-term potentiation and depotentiation in the hippocampal CA1 region of mice with type 2 diabetes mellitus. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555354. |
a previous study has reported that an association exists between γ-aminobutyric acid (gaba) and the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |