| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Blandini, J T Greenamyr. Prospects of glutamate antagonists in the therapy of Parkinson's disease. Fundamental & clinical pharmacology. vol 12. issue 1. 1998-05-06. PMID:9523179. |
due to the close relationship that links dopaminergic and glutamatergic neurotransmission, glutamate is directly involved in the functional alterations of basal ganglia circuitry that lead to the development of parkinsonian motor symptoms. |
1998-05-06 |
2023-08-12 |
Not clear |
| D Durstewitz, S Kröner, H C Hemmings, O Güntürkü. The dopaminergic innervation of the pigeon telencephalon: distribution of DARPP-32 and co-occurrence with glutamate decarboxylase and tyrosine hydroxylase. Neuroscience. vol 83. issue 3. 1998-04-02. PMID:9483560. |
no case of colocalization of glutamate decarboxylase and darpp-32 and no co-occurrence of glutamate decarboxylase-positive neurons and tyrosine hydroxylase-basket-like structures could be detected out of more than 2000 glutamate decarboxylase-positive neurons examined, although the high darpp-32 and high tyrosine hydroxylase staining density hampered this analysis in the basal ganglia. |
1998-04-02 |
2023-08-12 |
pigeon |
| L Naudon, J M Delfs, N Clavel, J F Lorden, M F Chessele. Differential expression of glutamate decarboxylase messenger RNA in cerebellar Purkinje cells and deep cerebellar nuclei of the genetically dystonic rat. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466432. |
although in humans dystonia is often the result of pathology in the basal ganglia, previous studies have revealed electrophysiological abnormalities and alterations in glutamate decarboxylase, the synthetic enzyme for gaba, in the cerebellum of dystonic rats. |
1998-03-26 |
2023-08-12 |
human |
| C M Testa, I K Friberg, S W Weiss, D G Standaer. Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia. The Journal of comparative neurology. vol 390. issue 1. 1998-03-03. PMID:9456172. |
immunohistochemical localization of metabotropic glutamate receptors mglur1a and mglur2/3 in the rat basal ganglia. |
1998-03-03 |
2023-08-12 |
rat |
| C M Testa, I K Friberg, S W Weiss, D G Standaer. Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia. The Journal of comparative neurology. vol 390. issue 1. 1998-03-03. PMID:9456172. |
metabotropic glutamate receptors (mglurs), which couple glutamate to second messengers, have important roles in the regulation of movement by the basal ganglia. |
1998-03-03 |
2023-08-12 |
rat |
| J Shi, Y Q Zhang, J W Simpkin. Effects of 17beta-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the rats. Experimental brain research. vol 117. issue 2. 1998-02-04. PMID:9419067. |
glut 1 protein decreased in both ovx and e2 groups by 24.6% and 22.7% respectively (p < 0.05) compared with the non-lesioned side in the core ischemic region, including the basal ganglia. |
1998-02-04 |
2023-08-12 |
rat |
| A Abbott, M A Wigmore, M G Lace. Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor. Brain research. vol 766. issue 1-2. 1998-01-02. PMID:9359599. |
the subthalamic nucleus (sthn) provides a glutamate mediated excitatory drive to several other component nuclei of the basal ganglia, thereby significantly influencing locomotion and control of voluntary movement. |
1998-01-02 |
2023-08-12 |
rat |
| S Z Meng, J Ohyu, S Takashim. Changes in AMPA glutamate and dopamine D2 receptors in hypoxic-ischemic basal ganglia necrosis. Pediatric neurology. vol 17. issue 2. 1997-12-31. PMID:9367294. |
changes in ampa glutamate and dopamine d2 receptors in hypoxic-ischemic basal ganglia necrosis. |
1997-12-31 |
2023-08-12 |
Not clear |
| S Z Meng, J Ohyu, S Takashim. Changes in AMPA glutamate and dopamine D2 receptors in hypoxic-ischemic basal ganglia necrosis. Pediatric neurology. vol 17. issue 2. 1997-12-31. PMID:9367294. |
changes in the ampa glutamate receptor subunits (glur1, 2-3, and 4) and dopamine d2 receptor (d2r) were investigated in 16 cases of hypoxic-ischemic basal ganglia necrosis (bgn) by immunohistochemistry. |
1997-12-31 |
2023-08-12 |
Not clear |
| U Wüllner, D G Standaert, C M Testa, J B Penney, A B Youn. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain research. vol 768. issue 1-2. 1997-12-18. PMID:9369318. |
glutamate is the principal excitatory transmitter of the mammalian brain and plays a particularly important role in the physiology of the basal ganglia structures responsible for movement regulation. |
1997-12-18 |
2023-08-12 |
rat |
| U Wüllner, D G Standaert, C M Testa, J B Penney, A B Youn. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain research. vol 768. issue 1-2. 1997-12-18. PMID:9369318. |
these results demonstrate that the neuronal structures comprising the basal ganglia express a distinct combination of kainate receptor subunit genes, suggesting that the pharmacological properties of the resultant glutamate receptors are likely to be regionally specific. |
1997-12-18 |
2023-08-12 |
rat |
| O Bar-Peled, H Ben-Hur, A Biegon, Y Groner, S Dewhurst, A Furuta, J D Rothstei. Distribution of glutamate transporter subtypes during human brain development. Journal of neurochemistry. vol 69. issue 6. 1997-12-12. PMID:9375691. |
eaat2 was the most prominent glutamate transporter subtype and was highly enriched in cortex, basal ganglia, cerebellum, and thalamus in all ages examined. |
1997-12-12 |
2023-08-12 |
human |
| V Bernard, P Somogyi, J P Bola. Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 2. 1997-11-28. PMID:8987803. |
glutamate released in the basal ganglia is involved in the expression of clinical symptoms of neurodegenerative diseases like parkinson's or huntington's. |
1997-11-28 |
2023-08-12 |
rat |
| S Z Meng, T Obonai, H Isumi, S Takashim. A developmental expression of AMPA-selective glutamate receptor subunits in human basal ganglia. Brain & development. vol 19. issue 6. 1997-11-26. PMID:9339865. |
a developmental expression of ampa-selective glutamate receptor subunits in human basal ganglia. |
1997-11-26 |
2023-08-12 |
human |
| S Z Meng, T Obonai, H Isumi, S Takashim. A developmental expression of AMPA-selective glutamate receptor subunits in human basal ganglia. Brain & development. vol 19. issue 6. 1997-11-26. PMID:9339865. |
the development of ampa-selective glutamate receptors (glur1 and glur2-3) in human basal ganglia (bg) was investigated in 23 normal brains by means of an immunohistochemical method. |
1997-11-26 |
2023-08-12 |
human |
| P A Löschmann, U Wüllner, M T Heneka, J B Schulz, M Kunow, H Wachtel, T Klockgethe. Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215597. |
these results suggest that rotations induced by combined treatment with glutamate antagonists and da agonists are mediated by different pathways within the basal ganglia, depending on which subtype of receptor is involved. |
1997-09-09 |
2023-08-12 |
rat |
| W J Schmidt, B D Kretschme. Behavioural pharmacology of glutamate receptors in the basal ganglia. Neuroscience and biobehavioral reviews. vol 21. issue 4. 1997-08-05. PMID:9195596. |
behavioural pharmacology of glutamate receptors in the basal ganglia. |
1997-08-05 |
2023-08-12 |
Not clear |
| W J Schmidt, B D Kretschme. Behavioural pharmacology of glutamate receptors in the basal ganglia. Neuroscience and biobehavioral reviews. vol 21. issue 4. 1997-08-05. PMID:9195596. |
glutamate receptors play a major role in the transmitter balance within the basal ganglia (bg). |
1997-08-05 |
2023-08-12 |
Not clear |
| M S Starr, B S Starr, S Kau. Stimulation of basal and L-DOPA-induced motor activity by glutamate antagonists in animal models of Parkinson's disease. Neuroscience and biobehavioral reviews. vol 21. issue 4. 1997-08-05. PMID:9195601. |
in parkinsonism, glutamate pathways within the basal ganglia become overactive, leading to the suggestion that glutamate antagonists might possess antiparkinsonian qualities. |
1997-08-05 |
2023-08-12 |
Not clear |
| C S Biggs, M S Star. Dopamine and glutamate control each other's release in the basal ganglia: a microdialysis study of the entopeduncular nucleus and substantia nigra. Neuroscience and biobehavioral reviews. vol 21. issue 4. 1997-08-05. PMID:9195608. |
dopamine and glutamate control each other's release in the basal ganglia: a microdialysis study of the entopeduncular nucleus and substantia nigra. |
1997-08-05 |
2023-08-12 |
rat |