| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G Murer, G Dziewczapolski, P Salin, M Vila, K Y Tseng, M Ruberg, M Rubinstein, M A Kelly, D K Grandy, M J Low, E Hirsch, R Raisman-Vozari, O Gershani. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. vol 99. issue 4. 2000-11-07. PMID:10974427. |
in addition, d(2) receptor-deficient mice display a reduced expression of glutamate decarboxylase-67 messenger rna in the globus pallidus, as the basal ganglia model predicts. |
2000-11-07 |
2023-08-12 |
mouse |
| M G Murer, G Dziewczapolski, P Salin, M Vila, K Y Tseng, M Ruberg, M Rubinstein, M A Kelly, D K Grandy, M J Low, E Hirsch, R Raisman-Vozari, O Gershani. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. vol 99. issue 4. 2000-11-07. PMID:10974427. |
finally, glutamate decarboxylase-67 messenger rna expression in the basal ganglia output nuclei was not affected by mutations in the d(2) receptor gene, a fact that could probably be related to the absence of a parkinsonian locomotor phenotype in d(2) receptor-deficient mice. |
2000-11-07 |
2023-08-12 |
mouse |
| E A Nansen, E S Jokel, M K Lobo, P E Micevych, M A Ariano, M S Levin. Striatal ionotropic glutamate receptor ontogeny in the rat. Developmental neuroscience. vol 22. issue 4. 2000-10-11. PMID:10965155. |
these results support a functional emergence of different glutamate receptor activation within the striatum and provide a potential therapeutic means to isolate developmental disorders specifically associated with excitatory circuits of the basal ganglia. |
2000-10-11 |
2023-08-12 |
rat |
| P Ravenscroft, J Brotchi. NMDA receptors in the basal ganglia. Journal of anatomy. vol 196 ( Pt 4). 2000-08-22. PMID:10923988. |
glutamate receptors play a major role in neurotransmission within the basal ganglia and are present in all nuclei of the basal ganglia. |
2000-08-22 |
2023-08-12 |
Not clear |
| R J McPherson, J F Marshal. Substantia nigra glutamate antagonists produce contralateral turning and basal ganglia Fos expression: interactions with D1 and D2 dopamine receptor agonists. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819899. |
substantia nigra glutamate antagonists produce contralateral turning and basal ganglia fos expression: interactions with d1 and d2 dopamine receptor agonists. |
2000-06-06 |
2023-08-12 |
rat |
| R J McPherson, J F Marshal. Substantia nigra glutamate antagonists produce contralateral turning and basal ganglia Fos expression: interactions with D1 and D2 dopamine receptor agonists. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819899. |
experiments measuring behavior and immediate-early gene expression in the basal ganglia can reveal interactions between dopamine (da) and glutamate neurotransmission. |
2000-06-06 |
2023-08-12 |
rat |
| R J McPherson, J F Marshal. Substantia nigra glutamate antagonists produce contralateral turning and basal ganglia Fos expression: interactions with D1 and D2 dopamine receptor agonists. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819899. |
this report tests the interactions between striatal da receptors and nigral glutamate receptors on basal ganglia function by examining both contralateral turning and fos immunoreactivity in striatum and pallidum following unilateral intranigral microinfusions of glutamate antagonists given to intact and 6-ohda-lesioned rats. |
2000-06-06 |
2023-08-12 |
rat |
| S Z Meng, J Ohyu, M Itoh, S Takashim. Dopamine transporter and nitric oxide synthase in hypoxic-ischemic brain. Pediatric neurology. vol 22. issue 2. 2000-05-11. PMID:10738916. |
we speculate that glutamate excitotoxicity mediated by glutamate receptors 1, 2/3, and 4 and excessive dopaminergic excitatory activity may play important roles in hypoxic-ischemic basal ganglia necrosis and that nnos does not contribute to that condition. |
2000-05-11 |
2023-08-12 |
human |
| M Fowler, L Medina, A Reine. Immunohistochemical localization of NMDA- and AMPA-type glutamate receptor subunits in the basal ganglia of red-eared turtles. Brain, behavior and evolution. vol 54. issue 5. 2000-03-14. PMID:10640787. |
the results show that the thalamostriatal, corticostriatal and subthalamo-pallidal projection systems of turtles are glutamatergic and that similar basal ganglia cell types in turtles and mammals have largely similar glutamate receptor characteristics. |
2000-03-14 |
2023-08-12 |
Not clear |
| R Betarbet, R H Porter, J T Greenamyr. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of neurochemistry. vol 74. issue 3. 2000-03-09. PMID:10693949. |
glur1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. |
2000-03-09 |
2023-08-12 |
Not clear |
| R Betarbet, R H Porter, J T Greenamyr. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of neurochemistry. vol 74. issue 3. 2000-03-09. PMID:10693949. |
the excitatory neurotransmitter glutamate mediates neural signaling at crucial points of this circuitry, and glutamate receptors are differentially distributed in the basal ganglia. |
2000-03-09 |
2023-08-12 |
Not clear |
| J A Kearney, R L Albi. Intrasubthalamic nucleus metabotropic glutamate receptor activation: a behavioral, Fos immunohistochemical and [14C]2-deoxyglucose autoradiographic study. Neuroscience. vol 95. issue 2. 2000-02-29. PMID:10658620. |
this suggests that metabotropic glutamate receptor stimulation results in altered subthalamic nucleus activity with consequent altered basal ganglia activity on the injected side. |
2000-02-29 |
2023-08-12 |
rat |
| J A Kearney, R L Albi. Intrasubthalamic nucleus metabotropic glutamate receptor activation: a behavioral, Fos immunohistochemical and [14C]2-deoxyglucose autoradiographic study. Neuroscience. vol 95. issue 2. 2000-02-29. PMID:10658620. |
however, examination of [14c]2-deoxyglucose uptake suggests that the alterations in basal ganglia activity are different following group ii versus group iii metabotropic glutamate receptor stimulation, suggesting that rotation is occurring via different mechanisms. |
2000-02-29 |
2023-08-12 |
rat |
| J H Abraini, B Kriem, J C Rostai. Administration of the glutamate uptake inhibitor L-trans-PDC in the globus pallidus and the substantia nigra, but not in the striatum, attenuates the psychostimulant effect of high helium pressure on locomotor activity in the rat. Neuroscience research. vol 35. issue 4. 2000-02-07. PMID:10617318. |
according to current thinking on basal ganglia function and previous data, it is suggested that high helium pressure would lead to a reduction of glutamate transmission in the snr that could contribute to a reduction in activity of the nigrothalamic gaba pathway and then to the occurrence of lma. |
2000-02-07 |
2023-08-12 |
rat |
| V Petegnief, J Saura, D Dewar, D J Cummins, M Dragunow, N Mah. Long-term effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione in the rat basal ganglia: calcification, changes in glutamate receptors and glial reactions. Neuroscience. vol 94. issue 1. 2000-01-14. PMID:10613501. |
long-term effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione in the rat basal ganglia: calcification, changes in glutamate receptors and glial reactions. |
2000-01-14 |
2023-08-12 |
rat |
| K R Müller-Vahl, H Kolbe, U Schneider, H M Emric. Cannabis in movement disorders. Forschende Komplementarmedizin. vol 6 Suppl 3. 2000-01-05. PMID:10627163. |
furthermore, there is evidence that endogenous cannabinoid transmission plays a role in the manipulation of other transmitter systems within the basal ganglia by increasing gabaergic transmission, inhibiting glutamate release and affecting dopaminergic uptake. |
2000-01-05 |
2023-08-12 |
Not clear |
| C M Kosinski, S Risso Bradley, P J Conn, A I Levey, G B Landwehrmeyer, J B Penney, A B Young, D G Standaer. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. The Journal of comparative neurology. vol 415. issue 2. 1999-12-10. PMID:10545164. |
localization of metabotropic glutamate receptor 7 mrna and mglur7a protein in the rat basal ganglia. |
1999-12-10 |
2023-08-12 |
rat |
| C M Kosinski, S Risso Bradley, P J Conn, A I Levey, G B Landwehrmeyer, J B Penney, A B Young, D G Standaer. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. The Journal of comparative neurology. vol 415. issue 2. 1999-12-10. PMID:10545164. |
metabotropic glutamate receptors (mglurs) coupled to g-proteins have important roles in the regulation of basal ganglia function. |
1999-12-10 |
2023-08-12 |
rat |
| S M Rawls, J F McGinty, D M Terria. Presynaptic kappa-opioid and muscarinic receptors inhibit the calcium-dependent component of evoked glutamate release from striatal synaptosomes. Journal of neurochemistry. vol 73. issue 3. 1999-09-14. PMID:10461895. |
the finding that glutamate efflux evoked by l-trans-pdc from isolated striatal nerve endings was entirely calcium independent supports the notion that intact basal ganglia circuitry mediates the calcium-dependent effects of this agent on glutamate efflux in vivo. |
1999-09-14 |
2023-08-12 |
Not clear |
| M Mavridis, M J Besso. Dopamine-opiate interaction in the regulation of neostriatal and pallidal neuronal activity as assessed by opioid precursor peptides and glutamate decarboxylase messenger RNA expression. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426535. |
the haloperidol-induced decrease of pallidal glutamate decarboxylase messenger rna expression suggests, in keeping with the current functional model of the basal ganglia, that the activation of the striatopallidal projection produced by the interruption of neostriatal dopaminergic transmission reduces the gabaergic output of the globus pallidus. |
1999-09-09 |
2023-08-12 |
rat |