| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Louise C Parr-Brownlie, Stacey L Poloskey, Debra A Bergstrom, Judith R Walter. Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease. Experimental neurology. vol 217. issue 2. 2009-07-07. PMID:19268664. |
together, results show that robust oscillatory activity observed in basal ganglia output nuclei after dopamine cell lesion does not directly drive changes in pfn oscillatory activity. |
2009-07-07 |
2023-08-12 |
rat |
| Jarom E Hanson, Elisabeth Birdsall, Kristi S Seferian, Marcus A Crosby, Kristen A Keefe, James W Gibb, Glen R Hanson, Annette E Fleckenstei. Methamphetamine-induced dopaminergic deficits and refractoriness to subsequent treatment. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19326567. |
thus, this study describes a model of resistance, possibly explained by: 1) the existence of dopaminergic neurons that are a priori refractory to deficits caused by methamphetamine; 2) the existence of dopaminergic neurons made persistently resistant consequent to a neurotoxic methamphetamine exposure; and/or 3) altered activation of post-synaptic basal ganglia systems necessary for the elaboration of methamphetamine-induced dopamine neurotoxicity. |
2009-07-07 |
2023-08-12 |
rat |
| Wolfgang Enard, Sabine Gehre, Kurt Hammerschmidt, Sabine M Hölter, Torsten Blass, Mehmet Somel, Martina K Brückner, Christiane Schreiweis, Christine Winter, Reinhard Sohr, Lore Becker, Victor Wiebe, Birgit Nickel, Thomas Giger, Uwe Müller, Matthias Groszer, Thure Adler, Antonio Aguilar, Ines Bolle, Julia Calzada-Wack, Claudia Dalke, Nicole Ehrhardt, Jack Favor, Helmut Fuchs, Valérie Gailus-Durner, Wolfgang Hans, Gabriele Hölzlwimmer, Anahita Javaheri, Svetoslav Kalaydjiev, Magdalena Kallnik, Eva Kling, Sandra Kunder, Ilona Mossbrugger, Beatrix Naton, Ildikó Racz, Birgit Rathkolb, Jan Rozman, Anja Schrewe, Dirk H Busch, Jochen Graw, Boris Ivandic, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Leticia Quintanilla-Martinez, Holger Schulz, Eckhard Wolf, Wolfgang Wurst, Andreas Zimmer, Simon E Fisher, Rudolf Morgenstern, Thomas Arendt, Martin Hrabé de Angelis, Julia Fischer, Johannes Schwarz, Svante Pääb. A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell. vol 137. issue 5. 2009-06-22. PMID:19490899. |
although these mice are generally healthy, they have qualitatively different ultrasonic vocalizations, decreased exploratory behavior and decreased dopamine concentrations in the brain suggesting that the humanized foxp2 allele affects basal ganglia. |
2009-06-22 |
2023-08-12 |
mouse |
| Ravi Prakash, Amit Pathak, Sanjay Munda, Dhruv Bagat. Quetiapine effective in treatment of inappropriate sexual behavior of lewy body disease with predominant frontal lobe signs. American journal of Alzheimer's disease and other dementias. vol 24. issue 2. 2009-06-19. PMID:19129547. |
rapid eye movement sleep behavior disorder, severe neuroleptic sensitivity, and low dopamine transporter uptake in basal ganglia are other suggestive features. |
2009-06-19 |
2023-08-12 |
Not clear |
| N Simola, G Di Chiara, W M U Daniels, T Schallert, M Morell. Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19063947. |
repetitive stimulation of dopamine receptors located in the basal ganglia may lead to the manifestation of sensitized, abnormal, motor responses in dopamine-denervated rats. |
2009-05-20 |
2023-08-12 |
rat |
| Ken-ichi Okada, Keisuke Toyama, Yuka Inoue, Tadashi Isa, Yasushi Kobayash. Different pedunculopontine tegmental neurons signal predicted and actual task rewards. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 15. 2009-05-12. PMID:19369554. |
the pedunculopontine tegmental nucleus (pptn) of the brainstem receives afferent inputs from reward-related structures, including the cerebral cortices and the basal ganglia, and in turn provides strong excitatory projections to dopamine neurons. |
2009-05-12 |
2023-08-12 |
monkey |
| Bernhard H Meurers, Gustavo Dziewczapolski, Anton Bittner, Tao Shi, Fredrik Kamme, Clifford W Shult. Dopamine depletion induced up-regulation of HCN3 enhances rebound excitability of basal ganglia output neurons. Neurobiology of disease. vol 34. issue 1. 2009-05-05. PMID:19320057. |
dopamine depletion induced up-regulation of hcn3 enhances rebound excitability of basal ganglia output neurons. |
2009-05-05 |
2023-08-12 |
mouse |
| M G Morgese, T Cassano, S Gaetani, T Macheda, L Laconca, P Dipasquale, L Ferraro, T Antonelli, V Cuomo, A Giuffrid. Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2. Neurochemistry international. vol 54. issue 1. 2009-04-24. PMID:19010365. |
chronic use of levodopa, the most effective treatment for parkinson's disease, causes abnormal involuntary movements named dyskinesias, which are linked to maladaptive changes in plasticity and disturbances of dopamine and glutamate neurotransmission in the basal ganglia. |
2009-04-24 |
2023-08-12 |
rat |
| Marta G Vucković, Ruth I Wood, Daniel P Holschneider, Avery Abernathy, Daniel M Togasaki, Alexandra Smith, Giselle M Petzinger, Michael W Jakowe. Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. Neurobiology of disease. vol 32. issue 2. 2009-04-08. PMID:18718537. |
memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. |
2009-04-08 |
2023-08-12 |
mouse |
| Andrew H Mille. Norman Cousins Lecture. Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface. Brain, behavior, and immunity. vol 23. issue 2. 2009-04-02. PMID:18793712. |
our data also support a role for dopamine depletion as reflected by ifn-alpha-induced changes in behavior (psychomotor slowing and fatigue) and regional brain activity, which implicate the involvement of the basal ganglia, as well as the association of ifn-alpha-induced depressive-like behavior in rhesus monkeys with decreased cerebrospinal fluid concentrations of the dopamine metabolite, homovanillic acid. |
2009-04-02 |
2023-08-12 |
monkey |
| Fabrizio Stocch. The hypothesis of the genesis of motor complications and continuous dopaminergic stimulation in the treatment of Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 1. 2009-03-31. PMID:19131046. |
there is now accumulating evidence that several factors - the progressive pathology of parkinson's disease, the change in drug pharmacodynamics, and the pulsatile manner in which short-acting dopaminergic agents stimulate striatal dopamine receptors - are key contributors to the priming of the basal ganglia for induction of motor complications. |
2009-03-31 |
2023-08-12 |
Not clear |
| Katsushige Watanabe, Takako Kita, Hitoshi Kit. Presynaptic actions of D2-like receptors in the rat cortico-striato-globus pallidus disynaptic connection in vitro. Journal of neurophysiology. vol 101. issue 2. 2009-03-26. PMID:19073810. |
the cerebral cortex, the neostriatum (str), and the external segment of the globus pallidus (gpe) form a cortico-str-gpe disynaptic connection, which is one of the major connections in the basal ganglia circuitries and a target of dopamine modulation. |
2009-03-26 |
2023-08-12 |
rat |
| Lydia Kerkerian-Le Goff, Jean-Jacques Bacci, Loreline Jouve, Christophe Melon, Pascal Sali. Impact of surgery targeting the caudal intralaminar thalamic nuclei on the pathophysiological functioning of basal ganglia in a rat model of Parkinson's disease. Brain research bulletin. vol 78. issue 2-3. 2009-03-23. PMID:18790021. |
to address this issue, we have examined the effects of excitotoxic lesion of cm/pf and of 6-hydroxydopamine-induced lesion of nigral dopamine neurons, separately or in association, on gene expression of markers of neuronal activity in the rat basal ganglia (striatal neuropeptide precursors, gad67, cytochrome oxidase subunit i) by quantitative in situ hybridization histochemistry. |
2009-03-23 |
2023-08-12 |
rat |
| Petter Marklund, Anne Larsson, Eva Elgh, Jan Linder, Katrine Ahlström Riklund, Lars Forsgren, Lars Nyber. Temporal dynamics of basal ganglia under-recruitment in Parkinson's disease: transient caudate abnormalities during updating of working memory. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19036762. |
in view of the tonic/phasic dopamine hypothesis, which posits a functional division between phasic d(2)-dependent striatal updating processes and tonic d(1)-dependent prefrontal context-maintenance processes, we predicted that newly diagnosed, drug-naïve parkinson's disease patients, with selective striatal dopamine deprivation, would demonstrate transient rather than sustained activation changes in the basal ganglia during 2-back performance. |
2009-03-10 |
2023-08-12 |
Not clear |
| Petter Marklund, Anne Larsson, Eva Elgh, Jan Linder, Katrine Ahlström Riklund, Lars Forsgren, Lars Nyber. Temporal dynamics of basal ganglia under-recruitment in Parkinson's disease: transient caudate abnormalities during updating of working memory. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19036762. |
the present findings resonate well with the tonic/phasic dopamine account and suggest that basal ganglia under-recruitment associated with executive dysfunction in early parkinson's disease might predominantly stem from deficiencies in phasic executive components subserved by striatum. |
2009-03-10 |
2023-08-12 |
Not clear |
| I A Prescott, J O Dostrovsky, E Moro, M Hodaie, A M Lozano, W D Hutchiso. Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patients. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19050033. |
studies in rat striatal slices have shown dopamine to be an essential component of activity-dependent synaptic plasticity at the input to the basal ganglia, but dopamine is also released from ventrally projecting dendrites of the substantia nigra pars compacta (snc) on the substantia nigra pars reticulata (snr), a major output structure of the basal ganglia. |
2009-03-10 |
2023-08-12 |
rat |
| I A Prescott, J O Dostrovsky, E Moro, M Hodaie, A M Lozano, W D Hutchiso. Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patients. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19050033. |
our findings suggest that extrastriatal dopamine modulates activity-dependent synaptic plasticity at basal ganglia output neurons. |
2009-03-10 |
2023-08-12 |
rat |
| Yoland Smith, Rosa Villalb. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781680. |
striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and parkinsonian brains. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yoland Smith, Rosa Villalb. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781680. |
dopamine has long been recognized to be a key neuromodulator of basal ganglia function, essential for normal motor activity. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yoland Smith, Rosa Villalb. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781680. |
the recent years have witnessed significant advances in our knowledge of dopamine function in the basal ganglia. |
2009-02-13 |
2023-08-12 |
Not clear |