| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miho Murat. Zonisamide: a new drug for Parkinson's disease. Drugs of today (Barcelona, Spain : 1998). vol 46. issue 4. 2010-08-18. PMID:20502722. |
zonisamide has multiple modes of action, and its effects on parkinson's disease include activation of dopamine synthesis, inhibition of monoamine oxidase, inhibition of t-type calcium channels and inhibition of an indirect pathway in the basal ganglia through the δ opioid receptor. |
2010-08-18 |
2023-08-12 |
Not clear |
| Ana Paula Zarzur, Isabella Sebusiani Duarte, Gabrielle do Nascimento Holanda, Gabrielle do Nascimento Holanda Gonçalves, Maria Angela Ueda Russo Martin. Laryngeal electromyography and acoustic voice analysis in Parkinson's disease: a comparative study. Brazilian journal of otorhinolaryngology. vol 76. issue 1. 2010-08-02. PMID:20339688. |
parkinson's disease (pd) involves a progressive depletion of dopamine in the basal ganglia leading to motor alterations. |
2010-08-02 |
2023-08-12 |
Not clear |
| Unn Kristin Haukvik, Thomas McNeil, Ragnar Nesvåg, Erik Söderman, Erik Jönsson, Ingrid Agart. No effect of obstetric complications on basal ganglia volumes in schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 4. 2010-07-30. PMID:20193725. |
the basal ganglia contain dopamine receptors that are known to be involved in schizophrenia pathology and to be vulnerable to pre- and perinatal hypoxic insults. |
2010-07-30 |
2023-08-12 |
Not clear |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Ultrastructural localization and function of dopamine D1-like receptors in the substantia nigra pars reticulata and the internal segment of the globus pallidus of parkinsonian monkeys. The European journal of neuroscience. vol 31. issue 5. 2010-07-12. PMID:20374284. |
the motor symptoms of parkinson's disease (pd) are commonly attributed to striatal dopamine loss, but reduced dopamine innervation of basal ganglia output nuclei, the internal globus pallidus (gpi) and the substantia nigra pars reticulata (snr) may also contribute to symptoms and signs of pd. |
2010-07-12 |
2023-08-12 |
monkey |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Ultrastructural localization and function of dopamine D1-like receptors in the substantia nigra pars reticulata and the internal segment of the globus pallidus of parkinsonian monkeys. The European journal of neuroscience. vol 31. issue 5. 2010-07-12. PMID:20374284. |
together with our recent findings from normal monkeys, these data provide evidence that functional d1/d5 receptors are expressed in gpi and snr in both normal and parkinsonian states, and that their activation by endogenous dopamine (under normal conditions) or dopamine receptor agonists (in parkinsonism) may regulate basal ganglia outflow. |
2010-07-12 |
2023-08-12 |
monkey |
| Jason M Williams, Dejan Milatovic, John C Gore, Michael Aschner, Malcolm J Aviso. Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic resonance imaging study. Toxicological sciences : an official journal of the Society of Toxicology. vol 114. issue 2. 2010-06-21. PMID:20061340. |
the parkinsonian symptoms and increased mn accumulation in dopaminergic (daergic) neurons of the basal ganglia implicate impaired dopamine signaling in the neurotoxic effects of chronic manganese overexposure. |
2010-06-21 |
2023-08-12 |
rat |
| Mark D Humphries, Tony J Prescot. The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward. Progress in neurobiology. vol 90. issue 4. 2010-06-14. PMID:19941931. |
dopamine's key role in learning is reviewed within the three current major computational frameworks; we also show that the shell-based basal ganglia sub-circuits are well placed to generate the phasic burst and dip responses of dopaminergic neurons. |
2010-06-14 |
2023-08-12 |
Not clear |
| Mark D Humphries, Tony J Prescot. The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward. Progress in neurobiology. vol 90. issue 4. 2010-06-14. PMID:19941931. |
we detail dopamine's modulation of ventral basal ganglia's inputs by its actions on pre-synaptic terminals and post-synaptic membranes in the striatum, arguing that the complexity of these effects hint at computational roles for dopamine beyond current ideas. |
2010-06-14 |
2023-08-12 |
Not clear |
| Pei Chun Hsieh, Tzung Lieh Yeh, I Hui Lee, Hui Chun Huang, Po See Chen, Yen Kuang Yang, Nan Tsing Chiu, Ru Band Lu, Mei-Hsiu Lia. Correlation between errors on the Wisconsin Card Sorting Test and the availability of striatal dopamine transporters in healthy volunteers. Journal of psychiatry & neuroscience : JPN. vol 35. issue 2. 2010-06-02. PMID:20184806. |
although studies have indicated that the frontal lobe plays an important role in performance on the wisconsin card sorting test (wcst) and that basal ganglia play a specific role in frontal lobe function, the role of striatal dopamine (da) activity in performance on the wcst remains unclear. |
2010-06-02 |
2023-08-12 |
human |
| Mario Herrera-Marschitz, Gordon Arbuthnott, Urban Ungersted. The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond. Progress in neurobiology. vol 90. issue 2. 2010-05-26. PMID:20185033. |
the model was useful for proposing a role of dopamine receptors in the gating of the flow of information through different efferent pathways of the basal ganglia. |
2010-05-26 |
2023-08-12 |
rat |
| Catherine R G Jones, Marjan Jahanshah. The substantia nigra, the basal ganglia, dopamine and temporal processing. Journal of neural transmission. Supplementum. issue 73. 2010-05-14. PMID:20411776. |
the substantia nigra, the basal ganglia, dopamine and temporal processing. |
2010-05-14 |
2023-08-12 |
Not clear |
| Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matte. In vivo microdialysis in Parkinson's research. Journal of neural transmission. Supplementum. issue 73. 2010-05-14. PMID:20411781. |
parkinson's disease (pd) is a progressive neurodegenerative disorder that is primarily characterized by the degeneration of dopamine (da) neurons in the nigrostriatal system, which in turn produces profound neurochemical changes within the basal ganglia, representing the neural substrate for parkinsonian motor symptoms. |
2010-05-14 |
2023-08-12 |
human |
| Arthur Leblois, Benjamin J Wendel, David J Perke. Striatal dopamine modulates basal ganglia output and regulates social context-dependent behavioral variability through D1 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 16. 2010-05-04. PMID:20410125. |
striatal dopamine modulates basal ganglia output and regulates social context-dependent behavioral variability through d1 receptors. |
2010-05-04 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
basal ganglia pathology in schizophrenia: dopamine connections and anomalies. |
2010-04-30 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
the basal ganglia are the site of most of the dopamine neurons in the brain and the target of anti-psychotic drugs. |
2010-04-30 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
in this review, we will start with an overview of basal ganglia anatomy emphasizing dopamine circuitry. |
2010-04-30 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
then, we will review the major deficits in dopamine function in schizophrenia, emphasizing the role of excessive dopamine in the basal ganglia and the link to psychosis. |
2010-04-30 |
2023-08-12 |
Not clear |
| Myung-Ji Lee, Chul-Eung Ki. Use of aripiprazole in clozapine induced enuresis: report of two cases. Journal of Korean medical science. vol 25. issue 2. 2010-04-28. PMID:20119596. |
aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. |
2010-04-28 |
2023-08-12 |
Not clear |
| Myung-Ji Lee, Chul-Eung Ki. Use of aripiprazole in clozapine induced enuresis: report of two cases. Journal of Korean medical science. vol 25. issue 2. 2010-04-28. PMID:20119596. |
we speculate that aripiprazole functioned as a d2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately. |
2010-04-28 |
2023-08-12 |
Not clear |
| Julie A Przybyla, Val J Watt. Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers. The Journal of pharmacology and experimental therapeutics. vol 332. issue 3. 2010-04-13. PMID:20016021. |
the cannabinoid cb(1) (cb(1)) and dopamine d(2) (d(2)) receptors are coexpressed in the basal ganglia, an area of the brain involved in such processes as cognition, motor function, and emotional control. |
2010-04-13 |
2023-08-12 |
Not clear |