| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
the basal ganglia are the site of most of the dopamine neurons in the brain and the target of anti-psychotic drugs. |
2010-04-30 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
in this review, we will start with an overview of basal ganglia anatomy emphasizing dopamine circuitry. |
2010-04-30 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Rosalinda C Robert. Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20089137. |
then, we will review the major deficits in dopamine function in schizophrenia, emphasizing the role of excessive dopamine in the basal ganglia and the link to psychosis. |
2010-04-30 |
2023-08-12 |
Not clear |
| Myung-Ji Lee, Chul-Eung Ki. Use of aripiprazole in clozapine induced enuresis: report of two cases. Journal of Korean medical science. vol 25. issue 2. 2010-04-28. PMID:20119596. |
aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. |
2010-04-28 |
2023-08-12 |
Not clear |
| Myung-Ji Lee, Chul-Eung Ki. Use of aripiprazole in clozapine induced enuresis: report of two cases. Journal of Korean medical science. vol 25. issue 2. 2010-04-28. PMID:20119596. |
we speculate that aripiprazole functioned as a d2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately. |
2010-04-28 |
2023-08-12 |
Not clear |
| Julie A Przybyla, Val J Watt. Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers. The Journal of pharmacology and experimental therapeutics. vol 332. issue 3. 2010-04-13. PMID:20016021. |
the cannabinoid cb(1) (cb(1)) and dopamine d(2) (d(2)) receptors are coexpressed in the basal ganglia, an area of the brain involved in such processes as cognition, motor function, and emotional control. |
2010-04-13 |
2023-08-12 |
Not clear |
| Glenda M Hallida. Thalamic changes in Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20082979. |
because dopamine replacement therapies largely alleviate these motor circuit abnormalities, it has been assumed that pathology in the basal ganglia is entirely responsible for the aberrant thalamic activity which then permeates the motor circuits. |
2010-03-31 |
2023-08-12 |
Not clear |
| Lydia Kerkerian-Le Goff, Loreline Jouve, Christophe Melon, Pascal Sali. Rationale for targeting the thalamic centre-median parafascicular complex in the surgical treatment of Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20082982. |
finally, the benefits provided by cm/pf-hfs were associated with widespread impact on the changes in neuronal metabolic activity induced by the dopamine depletion in the basal ganglia. |
2010-03-31 |
2023-08-12 |
rat |
| Erik Ch Wolter. Non-motor extranigral signs and symptoms in Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20083010. |
in this disease, synucleinopathic-induced, nigral dopamine deficiency-related dysfunction of the basal ganglia is held responsible for the characteristic levodopa-responsive motor signs and symptoms (bradykinesia, hypokinesia, rigidity), known as parkinsonism and essential for clinical diagnosis in pd, as well as subtle motivational and cognitive dysfunctions. |
2010-03-31 |
2023-08-12 |
Not clear |
| Fabrizio Stocch. The therapeutic concept of continuous dopaminergic stimulation (CDS) in the treatment of Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20083012. |
this hypothesis has arisen from studies of the normal basal ganglia demonstrating that nigral dopaminergic neurons normally fire continuously and striatal dopamine levels are relatively constant. |
2010-03-31 |
2023-08-12 |
monkey |
| Fabrizio Stocch. The therapeutic concept of continuous dopaminergic stimulation (CDS) in the treatment of Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20083012. |
in mptp monkeys, pulsatile stimulation of striatal dopamine receptors with short-acting agents is associated with the induction of molecular and physiologic changes in basal ganglia neurons and the development of motor complications. |
2010-03-31 |
2023-08-12 |
monkey |
| Jon-Eric VanLeeuwen, Giselle M Petzinger, John P Walsh, Garnik K Akopian, Marta Vuckovic, Michael W Jakowe. Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. Journal of neuroscience research. vol 88. issue 3. 2010-03-30. PMID:19746427. |
dopamine depletion leads to impaired motor performance and increased glutamatergic-mediated hyperexcitability of medium spiny neurons in the basal ganglia. |
2010-03-30 |
2023-08-12 |
mouse |
| Daniel G Dillon, Ryan Bogdan, Jesen Fagerness, Avram J Holmes, Roy H Perlis, Diego A Pizzagall. Variation in TREK1 gene linked to depression-resistant phenotype is associated with potentiated neural responses to rewards in humans. Human brain mapping. vol 31. issue 2. 2010-03-22. PMID:19621370. |
in control analyses, associations between basal ganglia responses to gains and functional polymorphisms in the dopamine transporter (dat1) and catechol-o-methyltransferase (comt) genes were also explored. |
2010-03-22 |
2023-08-12 |
Not clear |
| Naoya Hamaue, Akihiko Ogata, Mutsuko Terado, Shirou Tsuchida, Ichiro Yabe, Hidenao Sasaki, Masahiko Hirafuji, Hiroko Togashi, Takashi Aok. Entacapone, a catechol-O-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of Parkinson's disease induced by Japanese encephalitis virus. Brain research. vol 1309. 2010-02-26. PMID:19879254. |
entacapone, a catechol-o-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of parkinson's disease induced by japanese encephalitis virus. |
2010-02-26 |
2023-08-12 |
rat |
| Mohamed Khalil Tamim, Pershia Samadi, Marc Morissette, Laurent Grégoire, Bazoumana Ouattara, Daniel Lévesque, Claude Rouillard, Thérèse Di Paol. Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides. Neuropharmacology. vol 58. issue 1. 2010-02-25. PMID:19576910. |
dopamine denervation in parkinson's disease and repeated levodopa (l-dopa) administration that induces dyskinesias are associated with an enhancement of basal ganglia neuropeptide transmission. |
2010-02-25 |
2023-08-12 |
monkey |
| Irene Avila, Louise C Parr-Brownlie, Elena Brazhnik, Edward Castañeda, Debra A Bergstrom, Judith R Walter. Beta frequency synchronization in basal ganglia output during rest and walk in a hemiparkinsonian rat. Experimental neurology. vol 221. issue 2. 2010-02-16. PMID:19948166. |
the unilaterally lesioned rat model of parkinson's disease allows examination of this hypothesis by direct comparison of beta activity in basal ganglia output in non-lesioned and dopamine cell lesioned hemispheres during motor activity. |
2010-02-16 |
2023-08-12 |
rat |
| Rubing Zhao-Shea, Bruce N Cohen, Herwig Just, Tristan McClure-Begley, Paul Whiteaker, Sharon R Grady, Outi Salminen, Paul D Gardner, Henry A Lester, Andrew R Tappe. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 24. issue 1. 2010-02-02. PMID:19720621. |
recent studies suggest that high-affinity neuronal nicotinic acetylcholine receptors (nachrs) containing alpha4 and beta2 subunits (alpha4beta2*) functionally interact with g-protein-coupled dopamine (da) d(2) receptors in basal ganglia. |
2010-02-02 |
2023-08-12 |
mouse |
| Yun-Hai Qiu, Xin-Yin Wu, Hao Xu, David Sacket. Neuroimaging study of placebo analgesia in humans. Neuroscience bulletin. vol 25. issue 5. 2010-01-25. PMID:19784082. |
further pet studies with dopamine d2/d3 receptor-labeling radiotracer demonstrate that basal ganglia including nac are related to placebo analgesic responses. |
2010-01-25 |
2023-08-12 |
human |
| b' C\\xc3\\xa9sar Quiroz, Rafael Luj\\xc3\\xa1n, Motokazu Uchigashima, Ana Patr\\xc3\\xadcia Simoes, Talia N Lerner, Janusz Borycz, Anil Kachroo, Paula M Canas, Marco Orru, Michael A Schwarzschild, Diane L Rosin, Anatol C Kreitzer, Rodrigo A Cunha, Masahiko Watanabe, Sergi Ferr\\xc3\\xa. Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway. TheScientificWorldJournal. vol 9. 2010-01-07. PMID:19936569.' |
basal ganglia processing results from a balanced activation of direct and indirect striatal efferent pathways, which are controlled by dopamine d1 and d2 receptors, respectively. |
2010-01-07 |
2023-08-12 |
Not clear |
| S Arpin, E Lagrue, S Bodard, S Chalon, P Castelna. Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19789969. |
the membrane dopamine transporter (dat) density, which provides a reliable index of dopaminergic neurons survival in the basal ganglia, was assessed by semi-quantitative autoradiography of the striatum. |
2009-12-30 |
2023-08-12 |
mouse |