| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Charles B Mikell, Guy M McKhann, Solomon Segal, Robert A McGovern, Matthew B Wallenstein, Holly Moor. The hippocampus and nucleus accumbens as potential therapeutic targets for neurosurgical intervention in schizophrenia. Stereotactic and functional neurosurgery. vol 87. issue 4. 2009-10-21. PMID:19556835. |
multiple lines of evidence suggest that aberrantly high hippocampal activity may, via hippocampal connections with the limbic basal ganglia, drive excessive dopamine release into the striatum. |
2009-10-21 |
2023-08-12 |
Not clear |
| Patrick Bédard, Jerome N Sane. On a basal ganglia role in learning and rehearsing visual-motor associations. NeuroImage. vol 47. issue 4. 2009-10-15. PMID:19341805. |
a means to examine basal ganglia circuit contributions to associative motor learning is to examine these process in a lesion model system, such as parkinson's disease (pd), a basal ganglia disorder characterized by the loss of dopamine neurons. |
2009-10-15 |
2023-08-12 |
human |
| Rou-Chen Jee, Wen-Lung Tsao, Woei-Cherng Shyu, Pao-Sheng Yen, Yung-Hsiang Hsu, Shu-Hsin Li. Heroin vapor inhalation-induced spongiform leukoencephalopathy. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 108. issue 6. 2009-10-06. PMID:19515634. |
99m-technetium-trodat spect showed no definite decreased uptake of radiotracer at basal ganglia, which suggests that the dopamine neurons were not affected. |
2009-10-06 |
2023-08-12 |
Not clear |
| Michael J Frank, Randall C O'Reill. A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol. Behavioral neuroscience. vol 120. issue 3. 2009-09-30. PMID:16768602. |
taken together, the results support a unified account of the role of dopamine in modulating cognitive processes that depend on the basal ganglia. |
2009-09-30 |
2023-08-12 |
human |
| Anna Paschali, Velissarios Lakiotis, Lambros Messinis, Elli Markaki, Constantine Constantoyannis, John Ellul, Pavlos Vassilako. Dopamine transporter SPECT/CT and perfusion brain SPECT imaging in idiopathic basal ganglia calcinosis. Clinical nuclear medicine. vol 34. issue 7. 2009-09-30. PMID:19542944. |
dopamine transporter spect/ct and perfusion brain spect imaging in idiopathic basal ganglia calcinosis. |
2009-09-30 |
2023-08-12 |
Not clear |
| Kuei Y Tsen. Facing the lack of anti-phase oscillation in the parafascicular nucleus after dopamine depletion. Experimental neurology. vol 219. issue 1. 2009-09-25. PMID:19501087. |
results from this study demonstrate that a shift in firing pattern in basal ganglia output neurons does not directly drive the distinctive oscillatory activity observed in the parafascicular nucleus after dopamine depletion. |
2009-09-25 |
2023-08-12 |
rat |
| Matteo Bertelli, Brunilda Alushi, Arsenio Veicsteinas, H A Jinnah, Vanna Michel. Gene expression and mRNA editing of serotonin receptor 2C in brains of HPRT gene knock-out mice, an animal model of Lesch-Nyhan disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 16. issue 8. 2009-09-23. PMID:19473847. |
evidence exists for a role of basal ganglia dysfunction with decreased dopamine and excess serotonin striatal content. |
2009-09-23 |
2023-08-12 |
mouse |
| E Lagrue, B Abert, L Nadal, L Tabone, S Bodard, F Medja, A Lombes, S Chalon, P Castelna. MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood. Metabolic brain disease. vol 24. issue 2. 2009-09-14. PMID:19319673. |
this model also reproduced the biochemical and pathological features of ls: mptp increased plasmatic lactate levels (p = 0.023) and triggered basal ganglia degeneration, as evaluated through dopamine transporter (dat) autoradiography, tyrosine hydroxylase (th) immunohistochemistry, and dopamine dosage. |
2009-09-14 |
2023-08-12 |
mouse |
| Fu-Wen Zhou, Ying Jin, Shannon G Matta, Ming Xu, Fu-Ming Zho. An ultra-short dopamine pathway regulates basal ganglia output. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 33. 2009-09-11. PMID:19692618. |
together, our findings indicate that dendritically released dopamine tonically excites snr gaba neurons via d(1)-d(5) receptor coactivation that enhances constitutively active trpc3 channels, forming an ultra-short substantia nigra pars compacta --> snr dopamine pathway that regulates the firing intensity and pattern of these basal ganglia output neurons. |
2009-09-11 |
2023-08-12 |
mouse |
| Ming-Hong Chang, Wan-Ling Hung, Yi-Chu Liao, Yi-Chung Lee, Peiyuan F Hsie. Eye of the tiger-like MRI in parkinsonian variant of multiple system atrophy. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 7. 2009-09-08. PMID:19551461. |
dopamine transporter scans showed symmetric reduction of uptake over bilateral basal ganglia. |
2009-09-08 |
2023-08-12 |
Not clear |
| Gerrit N Brandt, Raphael M Bonell. Structural neuroimaging of the basal ganglia in schizophrenic patients: a review. Wiener medizinische Wochenschrift (1946). vol 158. issue 3-4. 2009-08-28. PMID:18330524. |
the basal ganglia structures have quickened interests in schizophrenia research for several reasons: on the one hand, schizophrenic patients are successfully treated with neuroleptics acting on dopamine receptors, which are highly concentrated in the basal ganglia structures. |
2009-08-28 |
2023-08-12 |
Not clear |
| Y-N Wu, J-J J Chen, L-Q Zhang, B I Hylan. Regulation of hind-limb tone by adenosine A2A receptor in rats. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409216. |
adenosine a2a receptor agonists produce a hypokinetic state (catalepsy) that is believed to reflect antagonistic interaction of a2a and dopamine d2 receptors in the basal ganglia. |
2009-08-20 |
2023-08-12 |
rat |
| Henrique Cerqueira Guimarães, Richard Levy, Antônio Lúcio Teixeira, Rogério Gomes Beato, Paulo Caramell. Neurobiology of apathy in Alzheimer's disease. Arquivos de neuro-psiquiatria. vol 66. issue 2B. 2009-08-14. PMID:18641892. |
accordingly, in this review article, we propose a pathophysiological model to explain apathetic behavior in alzheimer's disease, combining data from neuroimaging, neuropathology and experimental research on the role of orbito-frontal cortex, anterior cingulate cortex, basal ganglia and dopamine in decision-making neurobiology. |
2009-08-14 |
2023-08-12 |
Not clear |
| Paul D Morrison, R M Murra. From real-world events to psychosis: the emerging neuropharmacology of delusions. Schizophrenia bulletin. vol 35. issue 4. 2009-08-06. PMID:19487337. |
research over the last 4 decades has revealed the importance of dopamine (da), d2 receptors, and the basal ganglia in psychotic thinking. |
2009-08-06 |
2023-08-12 |
Not clear |
| Torsten Falk, Shiling Zhang, Scott J Sherma. Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's disease. Neuroscience letters. vol 458. issue 2. 2009-08-04. PMID:19442875. |
transplantation of retinal pigment epithelial (rpe) cells in the basal ganglia has been proposed as a novel cell-based therapy for parkinson's disease (pd), by providing a constant source of dopamine replacement via the melanin synthetic pathway enzyme tyrosinase. |
2009-08-04 |
2023-08-12 |
human |
| S Seidel, G Kasprian, F Leutmezer, D Prayer, E Auf. Disruption of nigrostriatal and cerebellothalamic pathways in dopamine responsive Holmes' tremor. Journal of neurology, neurosurgery, and psychiatry. vol 80. issue 8. 2009-07-30. PMID:18450789. |
beta-cit single photon emission computed tomography revealed abolished dopamine transporter activity in the left basal ganglia and striatum, in accordance with missing ipsilateral tegmento-frontal connectivity (medial forebrain bundle), demonstrated by diffusion tensor mri. |
2009-07-30 |
2023-08-12 |
Not clear |
| Daniella Rylander, Alessandra Recchia, Flora Mela, Andrzej Dekundy, Wojciech Danysz, M Angela Cenc. Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling. The Journal of pharmacology and experimental therapeutics. vol 330. issue 1. 2009-07-27. PMID:19357321. |
l-dopa-induced dyskinesia (lid) in parkinson's disease has been linked to altered dopamine and glutamate transmission within the basal ganglia. |
2009-07-27 |
2023-08-12 |
rat |
| Rodrigo A Bressan, Lucas C Quarantini, Sérgio B Andreoli, Celia Araújo, Gerome Breen, Camila Guindalini, Marcelo Hoexter, Andrea P Jackowski, Miguel R Jorge, Acioly L T Lacerda, Diogo R Lara, Stella Malta, Tais S Moriyama, Maria I Quintana, Wagner S Ribeiro, Juliana Ruiz, Aline F Schoedl, Ming C Shih, Ivan Figueira, Karestan C Koenen, Marcelo F Mello, Jair J Mar. The posttraumatic stress disorder project in Brazil: neuropsychological, structural and molecular neuroimaging studies in victims of urban violence. BMC psychiatry. vol 9. 2009-07-15. PMID:19480721. |
the third aim is to evaluate if patients with ptsd have decreased dopamine transporter density in the basal ganglia as compared to resilient controls subjects. |
2009-07-15 |
2023-08-12 |
human |
| Louise C Parr-Brownlie, Stacey L Poloskey, Debra A Bergstrom, Judith R Walter. Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease. Experimental neurology. vol 217. issue 2. 2009-07-07. PMID:19268664. |
to investigate the impact of increased oscillatory activity in basal ganglia output on pfn activity after dopamine cell lesion, pfn single-unit and local field potential activities were recorded in neurologically intact (control) rats and in both non-lesioned and dopamine lesioned hemispheres of unilateral 6-hydroxydopamine lesioned rats anesthetized with urethane. |
2009-07-07 |
2023-08-12 |
rat |
| Louise C Parr-Brownlie, Stacey L Poloskey, Debra A Bergstrom, Judith R Walter. Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease. Experimental neurology. vol 217. issue 2. 2009-07-07. PMID:19268664. |
furthermore, the decreased incidence of lts bursts is incompatible with inhibitory basal ganglia output inducing rebound bursting in pfn after dopamine lesion. |
2009-07-07 |
2023-08-12 |
rat |