Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ahmed A Moustafa, Szabolcs Keri, Mohammad M Herzallah, Catherine E Myers, Mark A Gluc. A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and cognition. vol 74. issue 2. 2011-06-30. PMID:20728258. |
building on our previous neurocomputational models of basal ganglia and hippocampal region function (and their modulation by dopamine and acetylcholine, respectively), we show here how an integration of these models can inform our understanding of the interaction between the basal ganglia and hippocampal region in associative learning and transfer generalization across various patient populations. |
2011-06-30 |
2023-08-12 |
Not clear |
Ahmed A Moustafa, Szabolcs Keri, Mohammad M Herzallah, Catherine E Myers, Mark A Gluc. A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and cognition. vol 74. issue 2. 2011-06-30. PMID:20728258. |
in particular, the model shows that simulating a loss of dopamine function in the basal ganglia module (as in pd) leads to slow acquisition learning but intact transfer generalization. |
2011-06-30 |
2023-08-12 |
Not clear |
J Lee, C L Parish, D Tomas, M K Horn. Chronic cocaine administration reduces striatal dopamine terminal density and striatal dopamine release which leads to drug-seeking behaviour. Neuroscience. vol 174. 2011-06-21. PMID:21129449. |
drug addiction is associated with altered dopamine (da) neurotransmission in the basal ganglia. |
2011-06-21 |
2023-08-12 |
rat |
Esther Fujimoto, Tamara J Stevenson, Chi-Bin Chien, Joshua L Bonkowsk. Identification of a dopaminergic enhancer indicates complexity in vertebrate dopamine neuron phenotype specification. Developmental biology. vol 352. issue 2. 2011-05-26. PMID:21276790. |
the dopaminergic neurons of the basal ganglia play critical roles in cns function and human disease, but specification of dopamine neuron phenotype is poorly understood in vertebrates. |
2011-05-26 |
2023-08-12 |
mouse |
Adarsh M Kumar, Raymond L Ownby, Drenna Waldrop-Valverde, Benny Fernandez, Mahendra Kuma. Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance. Journal of neurovirology. vol 17. issue 1. 2011-05-12. PMID:21165787. |
hiv-1 enters the brain soon after the initial infection and is distributed in varying concentrations in different regions with specific affinity to the subcortical regions, particularly the basal ganglia, causing neurodegeneration of dopaminergic regions and resulting in the decreased availability of dopamine (da) in the cns. |
2011-05-12 |
2023-08-12 |
human |
Adarsh M Kumar, Raymond L Ownby, Drenna Waldrop-Valverde, Benny Fernandez, Mahendra Kuma. Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance. Journal of neurovirology. vol 17. issue 1. 2011-05-12. PMID:21165787. |
the purpose of the present study was to investigate the relationship between the decreased availability of dopamine found in the postmortem brain regions (fronto-cortical regions, basal ganglia, caudate, putamen, globus pallidus, and substantia nigra) of individuals with hiv/aids and the antemortem level of performance (assessed as t scores) in different np functions. |
2011-05-12 |
2023-08-12 |
human |
Paul S Frankel, Amanda J Hoonakker, Mario E Alburges, Jacob W McDougall, Lisa M McFadden, Annette E Fleckenstein, Glen R Hanso. Effect of methamphetamine self-administration on neurotensin systems of the basal ganglia. The Journal of pharmacology and experimental therapeutics. vol 336. issue 3. 2011-04-21. PMID:21131268. |
even though many of the problems associated with abuse of meth are related to its profound actions on dopamine (da) basal ganglia systems, there currently are no approved medications to treat meth addiction. |
2011-04-21 |
2023-08-12 |
rat |
D Dardou, D Dassesse, L Cuvelier, T Deprez, M De Ryck, S N Schiffman. Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system. Brain research. vol 1367. 2011-04-15. PMID:20869353. |
altogether, our results suggest that sv2c may contribute to the regulation of neurotransmitter release and synaptic transmission in the basal ganglia including cholinergic striatal interneurons and nigro-striatal/mesolimbic dopamine neurons. |
2011-04-15 |
2023-08-12 |
mouse |
Ming-Lei Guo, Li-Min Mao, John Q Wan. Modulation of M4 muscarinic acetylcholine receptors by interacting proteins. Neuroscience bulletin. vol 26. issue 6. 2011-04-11. PMID:21113197. |
this is critical for maintaining the acetylcholine-dopamine balance in the basal ganglia, which determines the behavioral responsiveness to dopamine stimulation by psychostimulants. |
2011-04-11 |
2023-08-12 |
Not clear |
Leena Subramanian, John Vincent Hindle, Margaret Cecilia Jackson, David E J Linde. Dopamine boosts memory for angry faces in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 16. 2011-04-08. PMID:20960479. |
the dopamine pathways projecting to prefrontal cortex and the basal ganglia are assumed to play a major role in such emotion-cognition interactions. |
2011-04-08 |
2023-08-12 |
human |
Timothy P Gilmour, Christopher A Lieu, Mark J Nolt, Brigitte Piallat, Milind Deogaonkar, Thyagarajan Subramania. The effects of chronic levodopa treatments on the neuronal firing properties of the subthalamic nucleus and substantia nigra reticulata in hemiparkinsonian rhesus monkeys. Experimental neurology. vol 228. issue 1. 2011-03-30. PMID:21146527. |
dopamine replacement therapy with levodopa (ld) is currently the most effective pharmacological treatment for parkinson's disease (pd), a neurodegenerative disorder characterized by dysfunction of basal ganglia electrophysiology. |
2011-03-30 |
2023-08-12 |
monkey |
Yan Xu, Zhentao Zhang, Kairong Qin, Stella M Papa, Xuebing Ca. Quantitative autoradiographic study on receptor regulation in the basal ganglia in rat model of levodopa-induced motor complications. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 2. 2011-03-17. PMID:19399396. |
in order to study neurotransmitter receptor regulation in the basal ganglia involved in the functional changes underlying levodopa-induced motor complications, quantitative autoradiography was used to observe receptor bindings of dopamine d1 and d2, n-methyl-d-aspartate (nmda), amino-3-hydroxy-5-methylisoxazole propionic acid (ampa) and amino butyric acid (gaba) in the basal ganglia of rats that had unilateral nigrostriatal lesions and had been chronically treated with levodopa until motor complications developed. |
2011-03-17 |
2023-08-12 |
rat |
Jean Lud Cadet, Subramaniam Jayanthi, Michael T McCoy, Genevieve Beauvais, Ning Sheng Ca. Dopamine D1 receptors, regulation of gene expression in the brain, and neurodegeneration. CNS & neurological disorders drug targets. vol 9. issue 5. 2011-03-01. PMID:20632973. |
dopamine (da), the most abundant catecholamine in the basal ganglia, participates in the regulation of motor functions and of cognitive processes such as learning and memory. |
2011-03-01 |
2023-08-12 |
Not clear |
Melissa L Perreault, Ahmed Hasbi, Mohammed Alijaniaram, Theresa Fan, George Varghese, Paul J Fletcher, Philip Seeman, Brian F O'Dowd, Susan R Georg. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. The Journal of biological chemistry. vol 285. issue 47. 2011-02-28. PMID:20864528. |
the distribution and function of neurons coexpressing the dopamine d1 and d2 receptors in the basal ganglia and mesolimbic system are unknown. |
2011-02-28 |
2023-08-12 |
rat |
Emanuela Santini, Emmanuel Valjent, Gilberto Fison. mTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter. Cell cycle (Georgetown, Tex.). vol 9. issue 14. 2011-02-03. PMID:20581466. |
parkinson disease is caused by the progressive loss of dopamine innervation to the basal ganglia and is commonly treated with the dopamine precursor, l-dopa. |
2011-02-03 |
2023-08-12 |
mouse |
Monique Lavialle, Isabelle Denis, Philippe Guesnet, Sylvie Vancasse. Involvement of omega-3 fatty acids in emotional responses and hyperactive symptoms. The Journal of nutritional biochemistry. vol 21. issue 10. 2011-01-28. PMID:20434321. |
because the basal ganglia are involved in the control of locomotion and emotion, we examined published data regarding the role of n-3 pufa in dopamine (da) regulation in the basal ganglia. |
2011-01-28 |
2023-08-12 |
Not clear |
Ahmed A Moustafa, Mark A Gluc. A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. Journal of cognitive neuroscience. vol 23. issue 1. 2011-01-18. PMID:20044893. |
most existing models of dopamine and learning in parkinson disease (pd) focus on simulating the role of basal ganglia dopamine in reinforcement learning. |
2011-01-18 |
2023-08-12 |
Not clear |
Ahmed A Moustafa, Mark A Gluc. A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. Journal of cognitive neuroscience. vol 23. issue 1. 2011-01-18. PMID:20044893. |
in this model, pfc dopamine is key for attentional learning, whereas basal ganglia dopamine, consistent with other models, is key for reinforcement and motor learning. |
2011-01-18 |
2023-08-12 |
Not clear |
Ahmed A Moustafa, Mark A Gluc. A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. Journal of cognitive neuroscience. vol 23. issue 1. 2011-01-18. PMID:20044893. |
according to our model, pd is associated with decreased phasic and tonic dopamine levels in both pfc and basal ganglia. |
2011-01-18 |
2023-08-12 |
Not clear |
Ahmed A Moustafa, Mark A Gluc. A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. Journal of cognitive neuroscience. vol 23. issue 1. 2011-01-18. PMID:20044893. |
we assume that dopamine medications increase dopamine levels in both the basal ganglia and pfc, which, in turn, increase tonic dopamine levels but decrease the magnitude of phasic dopamine signaling in these brain structures. |
2011-01-18 |
2023-08-12 |
Not clear |