| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naama Parush, Naftali Tishby, Hagai Bergma. Dopaminergic Balance between Reward Maximization and Policy Complexity. Frontiers in systems neuroscience. vol 5. 2011-07-14. PMID:21603228. |
the resulting experience and dopamine modulated softmax policy can then serve as a theoretical framework to account for the broad range of behaviors and clinical states governed by the basal ganglia and dopamine systems. |
2011-07-14 |
2023-08-12 |
Not clear |
| Kristen K Ade, Yehong Wan, Meng Chen, Bernd Gloss, Nicole Calako. An Improved BAC Transgenic Fluorescent Reporter Line for Sensitive and Specific Identification of Striatonigral Medium Spiny Neurons. Frontiers in systems neuroscience. vol 5. 2011-07-14. PMID:21713123. |
for the study of basal ganglia physiology, reporters driven by type 1 and 2 dopamine receptors have been particularly useful for distinguishing the two classes of striatal projection neurons - striatonigral and striatopallidal. |
2011-07-14 |
2023-08-12 |
mouse |
| Melissa L Perreault, Ahmed Hasbi, Brian F O'Dowd, Susan R Georg. The dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in Basal Ganglia. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21747759. |
the dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia. |
2011-07-14 |
2023-08-12 |
Not clear |
| Melissa L Perreault, Ahmed Hasbi, Brian F O'Dowd, Susan R Georg. The dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in Basal Ganglia. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21747759. |
dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine d1 receptor and the neuropeptides dynorphin (dyn) and substance p, and the indirect striatopallidal pathway which expresses the dopamine d2 receptor and enkephalin (enk). |
2011-07-14 |
2023-08-12 |
Not clear |
| Melissa L Perreault, Ahmed Hasbi, Brian F O'Dowd, Susan R Georg. The dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in Basal Ganglia. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21747759. |
the aim of this review is to discuss the evidence in support of a novel third pathway coexpressing the d1 and d2 receptor, to discuss the potential relevance of this pathway to basal ganglia signaling, and to address its potential value, and that of the dopamine d1-d2 receptor heteromer, in the search for new therapeutic strategies for disorders involving dopamine neurotransmission. |
2011-07-14 |
2023-08-12 |
Not clear |
| Michael M Marvi, Mark F Le. Polycythemia and chorea. Handbook of clinical neurology. vol 100. 2011-07-12. PMID:21496586. |
proposed mechanisms for basal ganglia dysfunction include hypoperfusion due to venous stasis, receptor hypersensitivity in a setting of reduced catecholamine levels, and altered platelet dopamine metabolism. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ahmed A Moustafa, Szabolcs Keri, Mohammad M Herzallah, Catherine E Myers, Mark A Gluc. A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and cognition. vol 74. issue 2. 2011-06-30. PMID:20728258. |
building on our previous neurocomputational models of basal ganglia and hippocampal region function (and their modulation by dopamine and acetylcholine, respectively), we show here how an integration of these models can inform our understanding of the interaction between the basal ganglia and hippocampal region in associative learning and transfer generalization across various patient populations. |
2011-06-30 |
2023-08-12 |
Not clear |
| Ahmed A Moustafa, Szabolcs Keri, Mohammad M Herzallah, Catherine E Myers, Mark A Gluc. A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and cognition. vol 74. issue 2. 2011-06-30. PMID:20728258. |
in particular, the model shows that simulating a loss of dopamine function in the basal ganglia module (as in pd) leads to slow acquisition learning but intact transfer generalization. |
2011-06-30 |
2023-08-12 |
Not clear |
| J Lee, C L Parish, D Tomas, M K Horn. Chronic cocaine administration reduces striatal dopamine terminal density and striatal dopamine release which leads to drug-seeking behaviour. Neuroscience. vol 174. 2011-06-21. PMID:21129449. |
drug addiction is associated with altered dopamine (da) neurotransmission in the basal ganglia. |
2011-06-21 |
2023-08-12 |
rat |
| Esther Fujimoto, Tamara J Stevenson, Chi-Bin Chien, Joshua L Bonkowsk. Identification of a dopaminergic enhancer indicates complexity in vertebrate dopamine neuron phenotype specification. Developmental biology. vol 352. issue 2. 2011-05-26. PMID:21276790. |
the dopaminergic neurons of the basal ganglia play critical roles in cns function and human disease, but specification of dopamine neuron phenotype is poorly understood in vertebrates. |
2011-05-26 |
2023-08-12 |
mouse |
| Adarsh M Kumar, Raymond L Ownby, Drenna Waldrop-Valverde, Benny Fernandez, Mahendra Kuma. Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance. Journal of neurovirology. vol 17. issue 1. 2011-05-12. PMID:21165787. |
hiv-1 enters the brain soon after the initial infection and is distributed in varying concentrations in different regions with specific affinity to the subcortical regions, particularly the basal ganglia, causing neurodegeneration of dopaminergic regions and resulting in the decreased availability of dopamine (da) in the cns. |
2011-05-12 |
2023-08-12 |
human |
| Adarsh M Kumar, Raymond L Ownby, Drenna Waldrop-Valverde, Benny Fernandez, Mahendra Kuma. Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance. Journal of neurovirology. vol 17. issue 1. 2011-05-12. PMID:21165787. |
the purpose of the present study was to investigate the relationship between the decreased availability of dopamine found in the postmortem brain regions (fronto-cortical regions, basal ganglia, caudate, putamen, globus pallidus, and substantia nigra) of individuals with hiv/aids and the antemortem level of performance (assessed as t scores) in different np functions. |
2011-05-12 |
2023-08-12 |
human |
| Paul S Frankel, Amanda J Hoonakker, Mario E Alburges, Jacob W McDougall, Lisa M McFadden, Annette E Fleckenstein, Glen R Hanso. Effect of methamphetamine self-administration on neurotensin systems of the basal ganglia. The Journal of pharmacology and experimental therapeutics. vol 336. issue 3. 2011-04-21. PMID:21131268. |
even though many of the problems associated with abuse of meth are related to its profound actions on dopamine (da) basal ganglia systems, there currently are no approved medications to treat meth addiction. |
2011-04-21 |
2023-08-12 |
rat |
| D Dardou, D Dassesse, L Cuvelier, T Deprez, M De Ryck, S N Schiffman. Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system. Brain research. vol 1367. 2011-04-15. PMID:20869353. |
altogether, our results suggest that sv2c may contribute to the regulation of neurotransmitter release and synaptic transmission in the basal ganglia including cholinergic striatal interneurons and nigro-striatal/mesolimbic dopamine neurons. |
2011-04-15 |
2023-08-12 |
mouse |
| Ming-Lei Guo, Li-Min Mao, John Q Wan. Modulation of M4 muscarinic acetylcholine receptors by interacting proteins. Neuroscience bulletin. vol 26. issue 6. 2011-04-11. PMID:21113197. |
this is critical for maintaining the acetylcholine-dopamine balance in the basal ganglia, which determines the behavioral responsiveness to dopamine stimulation by psychostimulants. |
2011-04-11 |
2023-08-12 |
Not clear |
| Leena Subramanian, John Vincent Hindle, Margaret Cecilia Jackson, David E J Linde. Dopamine boosts memory for angry faces in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 16. 2011-04-08. PMID:20960479. |
the dopamine pathways projecting to prefrontal cortex and the basal ganglia are assumed to play a major role in such emotion-cognition interactions. |
2011-04-08 |
2023-08-12 |
human |
| Timothy P Gilmour, Christopher A Lieu, Mark J Nolt, Brigitte Piallat, Milind Deogaonkar, Thyagarajan Subramania. The effects of chronic levodopa treatments on the neuronal firing properties of the subthalamic nucleus and substantia nigra reticulata in hemiparkinsonian rhesus monkeys. Experimental neurology. vol 228. issue 1. 2011-03-30. PMID:21146527. |
dopamine replacement therapy with levodopa (ld) is currently the most effective pharmacological treatment for parkinson's disease (pd), a neurodegenerative disorder characterized by dysfunction of basal ganglia electrophysiology. |
2011-03-30 |
2023-08-12 |
monkey |
| Yan Xu, Zhentao Zhang, Kairong Qin, Stella M Papa, Xuebing Ca. Quantitative autoradiographic study on receptor regulation in the basal ganglia in rat model of levodopa-induced motor complications. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 2. 2011-03-17. PMID:19399396. |
in order to study neurotransmitter receptor regulation in the basal ganglia involved in the functional changes underlying levodopa-induced motor complications, quantitative autoradiography was used to observe receptor bindings of dopamine d1 and d2, n-methyl-d-aspartate (nmda), amino-3-hydroxy-5-methylisoxazole propionic acid (ampa) and amino butyric acid (gaba) in the basal ganglia of rats that had unilateral nigrostriatal lesions and had been chronically treated with levodopa until motor complications developed. |
2011-03-17 |
2023-08-12 |
rat |
| Jean Lud Cadet, Subramaniam Jayanthi, Michael T McCoy, Genevieve Beauvais, Ning Sheng Ca. Dopamine D1 receptors, regulation of gene expression in the brain, and neurodegeneration. CNS & neurological disorders drug targets. vol 9. issue 5. 2011-03-01. PMID:20632973. |
dopamine (da), the most abundant catecholamine in the basal ganglia, participates in the regulation of motor functions and of cognitive processes such as learning and memory. |
2011-03-01 |
2023-08-12 |
Not clear |
| Melissa L Perreault, Ahmed Hasbi, Mohammed Alijaniaram, Theresa Fan, George Varghese, Paul J Fletcher, Philip Seeman, Brian F O'Dowd, Susan R Georg. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. The Journal of biological chemistry. vol 285. issue 47. 2011-02-28. PMID:20864528. |
the distribution and function of neurons coexpressing the dopamine d1 and d2 receptors in the basal ganglia and mesolimbic system are unknown. |
2011-02-28 |
2023-08-12 |
rat |