| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie A Marusich, Mahesh Darna, A George Wilson, Emily D Denehy, Amanda Ebben, Agripina G Deaciuc, Linda P Dwoskin, Michael T Bardo, Timothy W Lefever, Jenny L Wiley, Chad J Reissig, Kia J Jackso. Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats. European journal of pharmacology. vol 814. 2018-06-01. PMID:28844873. |
effects of myosmine and anatabine on dopamine release may require a fully developed dopamine system, since no effects of these tobacco alkaloids were observed during adolescence. |
2018-06-01 |
2023-08-13 |
rat |
| Cody A Siciliano, Sara R Jone. Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 9. 2018-05-09. PMID:28139678. |
although the dopamine transporter (dat) is the primary site of action for cocaine, and the dopamine system is known to mediate the reinforcing effects of cocaine, the dopaminergic variations underlying individual differences in cocaine self-administration behaviors are not fully understood. |
2018-05-09 |
2023-08-13 |
rat |
| Albert C Yang, Shih-Jen Tsa. New Targets for Schizophrenia Treatment beyond the Dopamine Hypothesis. International journal of molecular sciences. vol 18. issue 8. 2018-04-17. PMID:28771182. |
schizophrenia has been primarily associated with dopamine dysfunction, and treatments have been developed that target the dopamine pathway in the central nervous system. |
2018-04-17 |
2023-08-13 |
Not clear |
| Katherine Stuhrman West, Aaron G Roseberr. Neuropeptide-Y alters VTA dopamine neuron activity through both pre- and postsynaptic mechanisms. Journal of neurophysiology. vol 118. issue 1. 2018-04-11. PMID:28469002. |
the mesocorticolimbic dopamine system, the brain's reward system, regulates many different behaviors including food intake, food reward, and feeding-related behaviors, and there is increasing evidence that hypothalamic feeding-related neuropeptides alter dopamine neuron activity to affect feeding. |
2018-04-11 |
2023-08-13 |
mouse |
| John Pierce Wise, Jason Canno. From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models. Toxicological sciences : an official journal of the Society of Toxicology. vol 153. issue 2. 2018-03-09. PMID:27473339. |
for the first time, we show that optn is enriched in dopamine neurons in the midbrain, and its expression is modulated by rotenone treatment in vivo here, animals were sampled at time-points both prior to overt neurodegeneration and after severe behavioral deficits, where a lesion to the nigrostriatal dopamine system is present. |
2018-03-09 |
2023-08-13 |
rat |
| Ana Weidenauer, Martin Bauer, Ulrich Sauerzopf, Lucie Bartova, Nicole Praschak-Rieder, Harald H Sitte, Siegfried Kasper, Matthäus Willei. Making Sense of: Sensitization in Schizophrenia. The international journal of neuropsychopharmacology. vol 20. issue 1. 2018-02-13. PMID:27613293. |
next to robust findings of an increased dopamine synthesis capacity in schizophrenia, empirical data and neuroimaging studies support the notion that the mesolimbic dopamine system of patients with schizophrenia is more reactive compared with healthy controls. |
2018-02-13 |
2023-08-13 |
human |
| Allison M Meyers, Devry Mourra, Jeff A Beele. High fructose corn syrup induces metabolic dysregulation and altered dopamine signaling in the absence of obesity. PloS one. vol 12. issue 12. 2018-02-07. PMID:29287121. |
impaired dopamine function is associated with obesity and high fat diet, but the effect of hfcs on the dopamine system has not been investigated. |
2018-02-07 |
2023-08-13 |
mouse |
| Megan L Fitzgerald, Suham A Kassir, Mark D Underwood, Mihran J Bakalian, J John Mann, Victoria Arang. Dysregulation of Striatal Dopamine Receptor Binding in Suicide. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27402414. |
to determine whether there are alterations in the striatal dopamine system in suicide, we conducted a quantitative autoradiographic survey of dopamine transporter (dat; [ |
2018-01-19 |
2023-08-13 |
Not clear |
| Antonia Manduca, Michela Servadio, Ruth Damsteegt, Patrizia Campolongo, Louk Jmj Vanderschuren, Viviana Trezz. Dopaminergic Neurotransmission in the Nucleus Accumbens Modulates Social Play Behavior in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26860202. |
thus, functional activity in the mesolimbic dopamine pathway plays an important role in adaptive social development, whereas abnormal nac dopamine function may underlie the social impairments observed in developmental psychiatric disorders such as autism, attention deficit hyperactivity disorder or early-onset schizophrenia. |
2018-01-09 |
2023-08-13 |
rat |
| Cody A Siciliano, Jason L Locke, Tiffany A Mathews, Marcelo F Lopez, Howard C Becker, Sara R Jone. Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains. Alcohol (Fayetteville, N.Y.). vol 58. 2018-01-03. PMID:27425261. |
given that the reinforcing and rewarding effects of ethanol are thought to be in part mediated by its actions on dopamine neurotransmission, we hypothesized that alcohol-preferring c57bl/6j and alcohol-avoiding dba/2j mice would display basal differences in dopamine system function. |
2018-01-03 |
2023-08-13 |
mouse |
| Takayo Sasagawa, Noriko Horii-Hayashi, Akinori Okuda, Takashi Hashimoto, Cho Azuma, Mayumi Nish. Long-term effects of maternal separation coupled with social isolation on reward seeking and changes in dopamine D1 receptor expression in the nucleus accumbens via DNA methylation in mice. Neuroscience letters. vol 641. 2017-12-12. PMID:28111354. |
we then focused on the mesolimbic dopamine pathway associated with reward-seeking behavior and measured both mrna and protein levels of tyrosine hydroxylase (th) in the ventral tegmental area (vta) and dopamine d1 and d2 receptors in the nucleus accumbens (nac). |
2017-12-12 |
2023-08-13 |
mouse |
| T Dahoun, S V Trossbach, N J Brandon, C Korth, O D Howe. The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28140405. |
here we summarise the impact of disc1 disruption on the dopamine system in animal models, considering its effects on presynaptic dopaminergic function (tyrosine hydroxylase levels, dopamine transporter levels, dopamine levels at baseline and after amphetamine administration) and postsynaptic dopaminergic function (dopamine d1 and d2 receptor levels, dopamine receptor-binding potential and locomotor activity after amphetamine administration). |
2017-11-16 |
2023-08-13 |
Not clear |
| K D Ersche, J Acosta-Cabronero, P S Jones, H Ziauddeen, R P L van Swelm, C M M Laarakkers, R Raha-Chowdhury, G B William. Disrupted iron regulation in the brain and periphery in cocaine addiction. Translational psychiatry. vol 7. issue 2. 2017-11-16. PMID:28221362. |
stimulant drugs acutely increase dopamine neurotransmission in the brain, and chronic use leads to neuroadaptive changes in the mesolimbic dopamine system and morphological changes in basal ganglia structures. |
2017-11-16 |
2023-08-13 |
Not clear |
| Michael Verwey, Alanna Grant, Nicholas Meti, Lauren Adye-White, Angelica Torres-Berrío, Veronique Rioux, Martin Lévesque, Frederic Charron, Cecilia Flore. Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon. eNeuro. vol 3. issue 3. 2017-10-31. PMID:27419218. |
based on these data, we suggest that cdon plays an important role encoding the diversity of dopamine neurons in the midbrain, influencing both the development of the mesocortical dopamine pathway and behavioral outputs that involve this neural circuitry. |
2017-10-31 |
2023-08-13 |
mouse |
| Toshio Matsud. Psychopharmacological Studies in Mice. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 136. issue 5. 2017-04-06. PMID:27150930. |
during this period, we identified a number of novel regulatory mechanisms that control the prefrontal dopamine system through functional interaction between serotonin1a and dopamine d2 receptors or between serotonin1a and σ1 receptors. |
2017-04-06 |
2023-08-13 |
mouse |
| Daniel Vallöf, Paola Maccioni, Giancarlo Colombo, Minja Mandrapa, Julia Winsa Jörnulf, Emil Egecioglu, Jörgen A Engel, Elisabet Jerlha. The glucagon-like peptide 1 receptor agonist liraglutide attenuates the reinforcing properties of alcohol in rodents. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:26303264. |
acute liraglutide treatment suppressed the well-documented effects of alcohol on the mesolimbic dopamine system, namely alcohol-induced accumbal dopamine release and conditioned place preference in mice. |
2016-12-20 |
2023-08-13 |
mouse |
| Heather Trantham-Davidson, L Judson Chandle. Alcohol-induced alterations in dopamine modulation of prefrontal activity. Alcohol (Fayetteville, N.Y.). vol 49. issue 8. 2016-09-27. PMID:26558348. |
this review summarizes the cellular effects of acute and chronic ethanol exposure on dopamine release and dopamine receptor function in the pfc with the goal of providing greater understanding of the effects of alcohol-use disorders on the dopamine system and how this relates to deficits in the executive function of the pfc. |
2016-09-27 |
2023-08-13 |
Not clear |
| John R Mantsch, David A Baker, Douglas Funk, Anh D Lê, Yavin Shaha. Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 1. 2016-09-22. PMID:25976297. |
neuropharmacology and circuitry studies indicate the involvement of crf and noradrenaline transmission in bed nucleus of stria terminalis and central amygdala, and dopamine, crf, kappa/dynorphin, and glutamate transmission in other components of the mesocorticolimbic dopamine system (ventral tegmental area, medial prefrontal cortex, orbitofrontal cortex, and nucleus accumbens). |
2016-09-22 |
2023-08-13 |
mouse |
| In-Seon Lee, Bombi Lee, Hi-Joon Park, Håkan Olausson, Paul Enck, Younbyoung Cha. A new animal model of placebo analgesia: involvement of the dopaminergic system in reward learning. Scientific reports. vol 5. 2016-09-21. PMID:26602173. |
cue preference is mediated by reward learning via the dopamine system, whereas the expression of placebo analgesia is mediated by the dopamine and opioid systems. |
2016-09-21 |
2023-08-13 |
Not clear |
| Elizabeth N Holly, Klaus A Micze. Ventral tegmental area dopamine revisited: effects of acute and repeated stress. Psychopharmacology. vol 233. issue 2. 2016-08-08. PMID:26676983. |
understanding which dopamine neurons are activated by stress, the neural mechanisms driving the activation, and where these neurons project will provide valuable insight into how stress can promote psychiatric disorders associated with the dopamine system, such as addiction and depression. |
2016-08-08 |
2023-08-13 |
Not clear |