| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yumeng Huang, Pei Wang, Rodrigo Morales, Qi Luo, Jianfang M. Map2k5-Deficient Mice Manifest Phenotypes and Pathological Changes of Dopamine Deficiency in the Central Nervous System. Frontiers in aging neuroscience. vol 13. 2021-06-26. PMID:34168549. |
in conclusion, this is the first study demonstrating that map2k5 mutant mice displayed phenotypes by disturbing the dopamine system in the central nervous system, implicating map2k5 mutant mouse as a promising model for many dopamine related disorders. |
2021-06-26 |
2023-08-13 |
mouse |
| Mia Ericson, Lisa Ulenius, Anna Andrén, Susanne Jonsson, Louise Adermark, Bo Söderpal. Different dopamine tone in ethanol high- and low-consuming Wistar rats. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:31099157. |
changes in the mesolimbic dopamine system have been postulated as a neurobiological underpinning of excessive alcohol consumption, and recent research also suggests that the amino acid taurine plays a central role in ethanol-induced dopamine elevation. |
2021-06-24 |
2023-08-13 |
rat |
| Mary K Estes, Jasric J Bland, Kenya K Ector, Melissa J Puppa, Douglas W Powell, Deranda B Leste. A high fat western diet attenuates phasic dopamine release. Neuroscience letters. vol 756. 2021-06-22. PMID:33979702. |
drugs of abuse, however, increase nac dopamine release to a greater extent and are known to induce lasting changes on the functioning of the mesolimbic dopamine pathway. |
2021-06-22 |
2023-08-13 |
mouse |
| Masumi Akiba, Kentaro Sugimoto, Risa Aoki, Ryo Murakami, Tomoyuki Miyashita, Riho Hashimoto, Anna Hiranuma, Junji Yamauchi, Taro Ueno, Takako Morimot. Dopamine modulates the optomotor response to unreliable visual stimuli in Drosophila melanogaster. The European journal of neuroscience. vol 51. issue 3. 2021-06-21. PMID:31834948. |
first, the effects of the dopamine system on the optomotor response were investigated in mutant flies deficient in dopamine receptors d1r1 or d1r2, which are involved in the modulation of sleep-arousal in flies. |
2021-06-21 |
2023-08-13 |
drosophila_melanogaster |
| Liesbeth Reneman, Marieke van der Pluijm, Anouk Schrantee, Elsmarieke van de Giesse. Imaging of the dopamine system with focus on pharmacological MRI and neuromelanin imaging. European journal of radiology. vol 140. 2021-06-02. PMID:34004428. |
different aspects of the dopamine system can be visualized and measured with positron emission tomography (pet) and single photon emission computed tomography (spect), including dopamine receptors, dopamine transporters, and dopamine release. |
2021-06-02 |
2023-08-13 |
Not clear |
| Alyssa G Yocky, Dan P Cove. Evolution of in vivo dopamine monitoring techniques. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33278398. |
we focus on the dopamine system for two reasons: (1) the central role of dopamine neurotransmission in normal behavior and disease, and (2) dopamine neuron measurements have long been at the forefront of in vivo neural monitoring technologies. |
2021-05-24 |
2023-08-13 |
Not clear |
| Donna K Hobgoo. ABO B gene is associated with introversion personality tendancies through linkage with dopamine beta hydroxylase gene. Medical hypotheses. vol 148. 2021-05-14. PMID:33548763. |
dopamine system has been linked to the introversion-extroversion spectrum with high dopamine linked to introversion. |
2021-05-14 |
2023-08-13 |
Not clear |
| Ja-Hyun Bai. Dopaminergic Control of the Feeding Circuit. Endocrinology and metabolism (Seoul, Korea). vol 36. issue 2. 2021-05-13. PMID:33820393. |
it appears that the dopamine system exerts a critical role in the control of feeding behavior not only by the reward-related circuit, but also by contributing to the homeostatic circuit of food intake, suggesting that dopamine plays an integrative role across the converging circuitry of control of food intake by linking energy state-associated signals to reward-related behaviors. |
2021-05-13 |
2023-08-13 |
Not clear |
| Mykel A Robble, Mary E Bozsik, Daniel S Wheeler, Robert A Wheele. Learned avoidance requires VTA KOR-mediated reductions in dopamine. Neuropharmacology. vol 167. 2021-04-23. PMID:32057802. |
while the mesolimbic dopamine system is known to be essential for reward learning, the characterization of a potential pattern of dopamine signaling that guides avoidance remains unknown. |
2021-04-23 |
2023-08-13 |
rat |
| Fanny Faivre, María-José Sánchez-Catalán, Sandra Dovero, Simone Bido, Anil Joshi, Erwan Bezard, Michel Barro. Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease. Neurobiology of disease. vol 139. 2021-04-12. PMID:32087289. |
these findings illustrate the major influence that the tvta exerts on the dopamine system, modulating the motor and non-motor symptoms related to a partial loss of dopamine cells. |
2021-04-12 |
2023-08-13 |
rat |
| Francesco Traccis, Valeria Serra, Claudia Sagheddu, Mauro Congiu, Pierluigi Saba, Gabriele Giua, Paola Devoto, Roberto Frau, Joseph Francois Cheer, Miriam Meli. Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats. International journal of molecular sciences. vol 22. issue 4. 2021-04-12. PMID:33562259. |
we have previously shown that male rat offspring prenatally exposed to Δ9-tetrahydrocannabinol (thc), a rat model of pce, exhibit extensive molecular, cellular, and synaptic changes in dopamine neurons of the ventral tegmental area (vta), resulting in a susceptible mesolimbic dopamine system associated with a psychotic-like endophenotype. |
2021-04-12 |
2023-08-13 |
rat |
| Peiyu Xu, Sijie Huang, Chunyou Mao, Brian E Krumm, X Edward Zhou, Yangxia Tan, Xi-Ping Huang, Yongfeng Liu, Dan-Dan Shen, Yi Jiang, Xuekui Yu, Hualiang Jiang, Karsten Melcher, Bryan L Roth, Xi Cheng, Yan Zhang, H Eric X. Structures of the human dopamine D3 receptor-G Molecular cell. vol 81. issue 6. 2021-04-01. PMID:33548201. |
structures of the human dopamine d3 receptor-g the dopamine system, including five dopamine receptors (d1r-d5r), plays essential roles in the central nervous system (cns), and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders. |
2021-04-01 |
2023-08-13 |
human |
| Kao Chin Chen, Yen Kuang Yang, Oliver D Howes, I Hui Lee, Tzung Lieh Yeh, Nan Tsing Chiu, Po See Chen, Anthony S David, Elvira Bramo. Striatal dopamine D Psychological medicine. 2021-03-08. PMID:33682657. |
striatal dopamine d the hyper-function of the striatal dopamine system has been suggested to underlie key pathophysiological mechanisms in schizophrenia. |
2021-03-08 |
2023-08-13 |
Not clear |
| Vaibhav R Konanur, Ted M Hsu, Scott E Kanoski, Matthew R Hayes, Mitchell F Roitma. Phasic dopamine responses to a food-predictive cue are suppressed by the glucagon-like peptide-1 receptor agonist Exendin-4. Physiology & behavior. vol 215. 2021-03-04. PMID:31821815. |
activation of central receptors for glucagon-like peptide-1 (glp-1r) via long-acting agonists (e.g., exendin-4) suppresses food intake and food-directed motivated behavior, in part, through action in regions with dopamine cell bodies, terminals, and/or neural populations that directly target the mesolimbic dopamine system. |
2021-03-04 |
2023-08-13 |
rat |
| Suzanne O Nolan, Jennifer E Zachry, Amy R Johnson, Lillian J Brady, Cody A Siciliano, Erin S Calipar. Direct dopamine terminal regulation by local striatal microcircuitry. Journal of neurochemistry. vol 155. issue 5. 2021-03-02. PMID:32356315. |
understanding the complexities of local regulation of dopamine signaling is required for building comprehensive frameworks of how activity throughout the dopamine system is integrated to drive signaling and control behavior. |
2021-03-02 |
2023-08-13 |
Not clear |
| Byeong Eun Lee, Hye Yun Kim, Hyun-Jin Kim, Hyeongsun Jeong, Byung-Gyu Kim, Ha-Eun Lee, Jieun Lee, Han Byeol Kim, Seung Eun Lee, Yong Ryoul Yang, Eugene C Yi, John A Hanover, Kyungjae Myung, Pann-Ghill Suh, Taejoon Kwon, Jae-Ick Ki. O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease. Brain : a journal of neurology. vol 143. issue 12. 2021-03-01. PMID:33300544. |
these findings provide insights into the functional importance of o-glcnacylation in the dopamine system, which may be utilized to protect dopamine neurons against parkinson's disease pathology. |
2021-03-01 |
2023-08-13 |
Not clear |
| Kristina Herfert, Julia G Mannheim, Laura Kuebler, Sabina Marciano, Mario Amend, Christoph Parl, Hanna Napieczynska, Florian M Maier, Salvador Castaneda Vega, Bernd J Pichle. Quantitative Rodent Brain Receptor Imaging. Molecular imaging and biology. vol 22. issue 2. 2021-02-22. PMID:31168682. |
while several studies have focused on the dopamine system due to the availability of several pet tracers which are sensitive to dopamine release, other neurotransmitter systems have become more and more into focus and are described in this review, as well. |
2021-02-22 |
2023-08-13 |
mouse |
| Jaime N Wertman, Nicole Melong, Matthew R Stoyek, Olivia Piccolo, Stewart Langley, Benno Orr, Shelby L Steele, Babak Razaghi, Jason N Berma. The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model. eLife. vol 9. 2021-02-16. PMID:32720645. |
of these, dopamine and l-mimosine, a plant-based amino acid active in the dopamine pathway, were further investigated. |
2021-02-16 |
2023-08-13 |
human |
| Robert A McCutcheon, John H Krystal, Oliver D Howe. Dopamine and glutamate in schizophrenia: biology, symptoms and treatment. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 19. issue 1. 2021-01-10. PMID:31922684. |
pharmacological and preclinical studies implicate both systems, and in vivo imaging of the dopamine system has consistently identified elevated striatal dopamine synthesis and release capacity in schizophrenia. |
2021-01-10 |
2023-08-13 |
Not clear |
| Robert A McCutcheon, John H Krystal, Oliver D Howe. Dopamine and glutamate in schizophrenia: biology, symptoms and treatment. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 19. issue 1. 2021-01-10. PMID:31922684. |
however, while genetic influences may directly underlie glutamatergic dysfunction, few genetic risk variants directly implicate the dopamine system, indicating that aberrant dopamine signalling is likely to be predominantly due to other factors. |
2021-01-10 |
2023-08-13 |
Not clear |