| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jesper Vestlund, Aimilia Lydia Kalafateli, Erik Studer, Lars Westberg, Elisabet Jerlha. Neuromedin U induces self-grooming in socially-stimulated mice. Neuropharmacology. vol 162. 2021-01-06. PMID:31647973. |
the mesolimbic dopamine system, including accumbal dopamine d2 receptors, was identified as a crucial downstream mechanism. |
2021-01-06 |
2023-08-13 |
mouse |
| Jessica A Mollick, Hedy Kobe. Computational models of drug use and addiction: A review. Journal of abnormal psychology. vol 129. issue 6. 2021-01-06. PMID:32757599. |
brain-based models have incorporated prefrontal cortex, basal ganglia, and the dopamine system, based on the effects of drugs on dopamine, motivation, and executive control circuits. |
2021-01-06 |
2023-08-13 |
human |
| Molly A Kwiatkowski, Zackary A Cope, Maria L Lavadia, Chuck J A van de Cappelle, Davide Dulcis, Jared W Youn. Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression. Scientific reports. vol 10. issue 1. 2020-12-07. PMID:32576854. |
a dysfunctional dopamine system is implicated in most psychiatric disorders, and genetic polymorphisms reducing expression of the dopamine transporter (dat) are associated with some conditions. |
2020-12-07 |
2023-08-13 |
mouse |
| D R Belov, E V Efimova, Z S Fesenko, K A Antonova, S F Kolodyazhny, A M Lakstygal, R R Gainetdino. Putative Trace-Amine Associated Receptor 5 (TAAR5) Agonist α-NETA Increases Electrocorticogram Gamma-Rhythm in Freely Moving Rats. Cellular and molecular neurobiology. vol 40. issue 2. 2020-11-18. PMID:31385135. |
to evaluate potential modulatory influence of a specific receptor for trace amines trace amine-associated receptor 5 (taar5) on the dopamine system, we used hplc measurements of dopamine and its metabolites in the mouse striatum following administration of the putative taar5 agonist α-neta. |
2020-11-18 |
2023-08-13 |
mouse |
| Ing-Mari Dohrn, Goran Papenberg, Elisabeth Winkler, Anna-Karin Welme. Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. The international journal of behavioral nutrition and physical activity. vol 17. issue 1. 2020-11-18. PMID:32448293. |
informed by animal and human data linking the dopamine system to motivation and reward processes, we investigated the associations between variations in dopamine genes and objectively measured physical activity and sedentary behaviour. |
2020-11-18 |
2023-08-13 |
human |
| Knud Larsen, Jamal Momeni, Leila Farajzadeh, Henrik Callesen, Christian Bendixe. Molecular characterization and analysis of the porcine Biochimie open. vol 3. 2020-10-01. PMID:29450128. |
nurr1 plays an important role in nigrostriatal dopamine neuron development and is therefore implicated in the pathogenesis of neurodegenerative diseases linked to the dopamine system of the midbrain. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kimberly C Thibeault, Munir Gunes Kutlu, Christina Sanders, Erin S Calipar. Cell-type and projection-specific dopaminergic encoding of aversive stimuli in addiction. Brain research. vol 1713. 2020-07-20. PMID:30580012. |
because the initial reinforcing effects of drugs are dependent on increases in dopamine in reward-related brain regions such as the mesolimbic dopamine pathway, a large focus of addiction research has centered on the dysregulation of this system and its control of positive reinforcement and motivation. |
2020-07-20 |
2023-08-13 |
Not clear |
| Stefanos Stagkourakis, Johan Dunevall, Zahra Taleat, Andrew G Ewing, Christian Broberge. Dopamine Release Dynamics in the Tuberoinfundibular Dopamine System. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 21. 2020-06-12. PMID:30782976. |
dopamine release dynamics in the tuberoinfundibular dopamine system. |
2020-06-12 |
2023-08-13 |
mouse |
| Heather E Soder, Troy A Webber, Marina A Bornovalova, Jong Y Park, Geoffrey F Pott. A test of dopamine hyper- and hyposensitivity in alcohol use. Addictive behaviors. vol 90. 2020-06-01. PMID:30530298. |
while dopamine hyposensitivity is common among chronic alcohol users, these data provide preliminary evidence that hypersensitivity of the dopamine system may underlie increased alcohol use in those who have not yet developed a chronic alcohol use disorder. |
2020-06-01 |
2023-08-13 |
human |
| Akanksha Mishra, Sonu Singh, Virendra Tiwari, Swati Chaturvedi, M Wahajuddin, Shubha Shukl. Dopamine receptor activation mitigates mitochondrial dysfunction and oxidative stress to enhance dopaminergic neurogenesis in 6-OHDA lesioned rats: A role of Wnt signalling. Neurochemistry international. vol 129. 2020-06-01. PMID:31078578. |
dopamine system regulates different aspects of behavioural phenotypes such as motor control, reward, anxiety and depression via acting on dopamine receptors (d1-d5). |
2020-06-01 |
2023-08-13 |
rat |
| Aimilia Lydia Kalafateli, Daniel Vallöf, Elisabet Jerlha. Activation of amylin receptors attenuates alcohol-mediated behaviours in rodents. Addiction biology. vol 24. issue 3. 2020-05-18. PMID:29405517. |
we showed that acute sct administration attenuated the established effects of alcohol on the mesolimbic dopamine system, particularly alcohol-induced locomotor stimulation and accumbal dopamine release. |
2020-05-18 |
2023-08-13 |
mouse |
| Elyssa B Margolis, Anushree N Karkhani. Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion. Neurochemistry international. vol 129. 2020-05-11. PMID:31301327. |
the dopamine system, through its contributions to reinforcement learning, is also involved in processing of aversive stimuli, and kor control of dopamine in the context of aversive behavioral states has been intensely studied. |
2020-05-11 |
2023-08-13 |
Not clear |
| Jeffrey M Hoyt, David J Perkel, Christine V Portfor. Dopamine Acts via D2-Like Receptors to Modulate Auditory Responses in the Inferior Colliculus. eNeuro. vol 6. issue 5. 2020-05-08. PMID:31548368. |
however, it was previously unknown which dopamine receptors are involved in modulating neuronal responses, and whether the observed preponderance of depressive effects reflects the endogenous dopamine system in the ic. |
2020-05-08 |
2023-08-13 |
mouse |
| E V Kur'yanova, V O Stupin, A V Tryasuchev, D L Teply. Effects of Blockage of Peripheral Choline, Serotonin, and Dopamine Receptors on Heart Rhythm Variability in Rats under Conditions of Stimulation of Neurotransmitter Systems. Bulletin of experimental biology and medicine. vol 168. issue 2. 2020-05-05. PMID:31776959. |
under conditions of serotoninergic system stimulation, the blockade of serotonin receptors was followed by a significant hr acceleration without changes in heart rhythm variability; blockade of dopamine receptors (sulpiride, 1 mg/kg) induced hr acceleration and increase in the amplitude of lf- and vlf-waves; blockade of dopamine receptors under conditions of dopamine system stimulation was followed by a significant increase in hr and a decrease in the amplitude of all waves of the heart rhythm variability. |
2020-05-05 |
2023-08-13 |
rat |
| Julian Rössler, Lui Unterassner, Thomas Wyss, Helene Haker, Peter Brugger, Wulf Rössler, Diana Wotrub. Schizotypal Traits are Linked to Dopamine-Induced Striato-Cortical Decoupling: A Randomized Double-Blind Placebo-Controlled Study. Schizophrenia bulletin. vol 45. issue 3. 2020-04-20. PMID:29878280. |
the dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis. |
2020-04-20 |
2023-08-13 |
human |
| Jesús Ramírez-Bermúdez, Ivan Perez-Neri, Sergio Montes, Francisco Nente, Marisol Ramirez-Abascal, Roger Carrillo-Mezo, Rodrigo Pérez-Esparza, Jose Luis Soto-Hernandez, Mariana Espinola-Nadurille, Leo Bayliss, Jose De Jesus Flores Rivera, Camilo Rio. Dopaminergic Hyperactivity in Neurological Patients with Delirium. Archives of medical research. vol 50. issue 8. 2020-04-20. PMID:32018069. |
the assessment of the dopamine system is particularly relevant, as dopamine antagonists are the most used drugs in delirium. |
2020-04-20 |
2023-08-13 |
Not clear |
| Xiao H Wang, Christopher L Souders, Priscilla Xavier, Xiao Y Li, Bing Yan, Christopher J Martyniu. The pyrethroid esfenvalerate induces hypoactivity and decreases dopamine transporter expression in embryonic/larval zebrafish (Danio rerio). Chemosphere. vol 243. 2020-04-06. PMID:31995874. |
based on evidence that dopamine regulates behavior and studies showing that other pyrethroids affect dopamine system, we measured transcripts involved in dopaminergic signaling. |
2020-04-06 |
2023-08-13 |
zebrafish |
| Claire E Stelly, Graham C Haug, Kaitlyn M Fonzi, Miriam A Garcia, Sean C Tritley, Alexa P Magnon, Maria Alicia P Ramos, Matthew J Wana. Pattern of dopamine signaling during aversive events predicts active avoidance learning. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 27. 2020-03-30. PMID:31209016. |
the mesolimbic dopamine system contributes to behaviors elicited by aversive stimuli, although it is unclear if the heterogeneity in active avoidance learning is explained by differences in dopamine transmission. |
2020-03-30 |
2023-08-13 |
Not clear |
| Thomas A Stalnaker, James D Howard, Yuji K Takahashi, Samuel J Gershman, Thorsten Kahnt, Geoffrey Schoenbau. Dopamine neuron ensembles signal the content of sensory prediction errors. eLife. vol 8. 2020-03-11. PMID:31674910. |
these data, combined with causal evidence that dopamine transients support sensory-based associative learning, suggest that the dopamine system signals a multidimensional prediction error. |
2020-03-11 |
2023-08-13 |
human |
| Earnest S Kim, K Matthew Latta. Context-Dependent and Context-Independent Effects of D1 Receptor Antagonism in the Basolateral and Central Amygdala during Cocaine Self-Administration. eNeuro. vol 6. issue 4. 2020-03-06. PMID:31358512. |
one way that drugs of abuse perturb the dopamine system is by triggering large amounts of extracellular dopamine to efflux into limbic regions. |
2020-03-06 |
2023-08-13 |
rat |