| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elisabet Jerlhag, Emil Egecioglu, Suzanne L Dickson, Jörgen A Enge. Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system. Addiction biology. vol 16. issue 1. 2011-04-25. PMID:20579004. |
finally the effects of peripheral ghrelin on locomotor stimulation and accumbal dopamine release were blocked by intra-vta administration of a ghs-r1a antagonist (bim28163), indicating that ghs-r1a signalling within the vta is required for the ghrelin-induced activation of the mesolimbic dopamine system. |
2011-04-25 |
2023-08-12 |
Not clear |
| Kenneth Blum, Amanda Lih-Chuan Chen, Eric R Braverman, David E Comings, Thomas J H Chen, Vanessa Arcuri, Seth H Blum, Bernard W Downs, Roger L Waite, Alison Notaro, Joel Lubar, Lonna Williams, Thomas J Prihoda, Tomas Palomo, Marlene Oscar-Berma. Attention-deficit-hyperactivity disorder and reward deficiency syndrome. Neuropsychiatric disease and treatment. vol 4. issue 5. 2011-04-21. PMID:19183781. |
a consensus of the literature suggests that when there is a dysfunction in the "brain reward cascade," especially in the dopamine system, causing a low or hypo-dopaminergic trait, the brain may require dopamine for individuals to avoid unpleasant feelings. |
2011-04-21 |
2023-08-12 |
Not clear |
| Suresh Babu Rangasamy, Katherine Soderstrom, Roy A E Bakay, Jeffrey H Kordowe. Neurotrophic factor therapy for Parkinson's disease. Progress in brain research. vol 184. 2011-01-21. PMID:20887879. |
experimental studies in animal models suggest that members of neurotrophin family and gdnf family of ligands (gfls) have the potent ability to protect degenerating dopamine neurons as well as promote regeneration of the nigrostriatal dopamine system. |
2011-01-21 |
2023-08-12 |
Not clear |
| Zivjena Vucetic, Teresa M Reye. Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity. Wiley interdisciplinary reviews. Systems biology and medicine. vol 2. issue 5. 2011-01-12. PMID:20836049. |
the interaction of dopamine with peripheral and central indices of nutritional status (e.g., leptin, ghrelin, neuropeptide y), and the susceptibility of the dopamine system to prenatal insults will be discussed. |
2011-01-12 |
2023-08-12 |
Not clear |
| Ariel B Brown, Joseph Biederman, Eve M Valera, Alysa E Doyle, George Bush, Thomas Spencer, Michael C Monuteaux, Eric Mick, Susan Whitfield-Gabrieli, Nikos Makris, Peter S LaViolette, Marlene Oscar-Berman, Stephen V Faraone, Larry J Seidma. Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 2. 2010-12-20. PMID:19676101. |
although attention-deficit/hyperactivity disorder (adhd) is associated both with brain alterations in attention and executive function (ef) circuitry and with genetic variations within the dopamine system (including the dopamine transporter gene [slc6a3]), few studies have directly investigated how genetic variations are linked to brain alterations. |
2010-12-20 |
2023-08-12 |
human |
| Maarten Loos, Jorn Staal, Anton N M Schoffelmeer, August B Smit, Sabine Spijker, Tommy Patti. Inhibitory control and response latency differences between C57BL/6J and DBA/2J mice in a Go/No-Go and 5-choice serial reaction time task and strain-specific responsivity to amphetamine. Behavioural brain research. vol 214. issue 2. 2010-11-16. PMID:20580749. |
furthermore, we extended previous reports on differences in the brain dopamine system of dba/2j and c57bl/6j mice, by showing differential gene expression levels of three dopamine receptors (drd1, drd4 and drd5) in the mpfc. |
2010-11-16 |
2023-08-12 |
mouse |
| Shunsuke Yagi, Etsuji Yoshikawa, Masami Futatsubashi, Masamichi Yokokura, Yujiro Yoshihara, Tatsuo Torizuka, Yasuomi Ouch. Progression from unilateral to bilateral parkinsonism in early Parkinson disease: implication of mesocortical dopamine dysfunction by PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 51. issue 8. 2010-09-01. PMID:20660377. |
here, we examined in vivo changes in the brain dopaminergic system using pet with a dopamine transporter radiotracer, (11)c-2-b-carbomethoxy-3b-(4-fluorophenyl) tropane ((11)c-cft), to elucidate the pathophysiologic characteristics of the dopamine system in early converters. |
2010-09-01 |
2023-08-12 |
Not clear |
| S D Hood, J P Potokar, S J C Davies, D A Hince, K Morris, K M Seddon, D J Nutt, S V Argyropoulo. Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants. Journal of psychopharmacology (Oxford, England). vol 24. issue 5. 2010-08-18. PMID:18838500. |
there appears to be instability of the dopamine system under behavioural stress in social anxiety subjects that is only partly rectified by successful treatment with an ssri, which may induce a desensitisation of postsynaptic dopamine d(3) receptors. |
2010-08-18 |
2023-08-12 |
human |
| Peipei Chau, Helga Höifödt-Lidö, Elin Löf, Bo Söderpalm, Mia Ericso. Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate. Alcoholism, clinical and experimental research. vol 34. issue 1. 2010-08-10. PMID:19860809. |
we have previously demonstrated that strychnine-sensitive glycine receptors (glyrs) in the nucleus accumbens (nac) and nicotinic acetylcholine receptors (nachrs) in the ventral tegmental area are involved in mediating ethanol (etoh)-induced elevation of dopamine in the rat mesolimbic dopamine system. |
2010-08-10 |
2023-08-12 |
rat |
| Alex Pine, Tamara Shiner, Ben Seymour, Raymond J Dola. Dopamine, time, and impulsivity in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592211. |
thus our findings reveal a novel mechanism by which dopamine influences human decision-making that can account for behavioral aberrations associated with a hyperfunctioning dopamine system. |
2010-07-22 |
2023-08-12 |
human |
| Stéphanie Vuillermot, Liz Weber, Joram Feldon, Urs Meye. A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107055. |
early interventions targeting the developing dopamine system may open new avenues for a successful attenuation or even prevention of psychotic disorders following neurodevelopmental disruption of dopamine functions. |
2010-07-08 |
2023-08-12 |
mouse |
| M Melis, M Pisti. Endocannabinoid signaling in midbrain dopamine neurons: more than physiology? Current neuropharmacology. vol 5. issue 4. 2010-06-10. PMID:19305743. |
since dopamine dysfunctions underlie diverse neuropsychiatric disorders including schizophrenia, psychoses, and drug addiction, the importance of better understanding the correlation between an unbalanced endocannabinoid signal and the dopamine system is even greater. |
2010-06-10 |
2023-08-12 |
Not clear |
| Dominic Thibault, Christian Kortleven, Caroline Fasano, Gregory Dal Bo, Louis-Eric Trudea. [Recent discoveries on the function and plasticity of central dopamine pathways]. Medecine sciences : M/S. vol 26. issue 2. 2010-06-08. PMID:20188048. |
recent work has unveiled novel and surprising properties of dopamine neurons and of other key players involved in regulating the dopamine system. |
2010-06-08 |
2023-08-12 |
Not clear |
| Dara K Shahrokh, Tie-Yuan Zhang, Josie Diorio, Alain Gratton, Michael J Meane. Oxytocin-dopamine interactions mediate variations in maternal behavior in the rat. Endocrinology. vol 151. issue 5. 2010-06-08. PMID:20228171. |
these studies reveal a direct effect of oxytocin on dopamine release within the mesocorticolimbic dopamine system and are consistent with previous reports of oxytocin-dopamine interactions in the establishment and maintenance of social bonds. |
2010-06-08 |
2023-08-12 |
rat |
| Simon Cervenka, J Petter Gustavsson, Christer Halldin, Lars Fard. Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability. NeuroImage. vol 50. issue 1. 2010-05-03. PMID:20004254. |
animal research has demonstrated a role for the dopamine system in social behaviour, and recent molecular imaging studies have shown a negative correlation between dopamine d2-receptor binding in the striatum and social desirability. |
2010-05-03 |
2023-08-12 |
human |
| Limin Liu, Yong Wang, Bo Li, Jun Jia, Zuoli Sun, Jinming Zhang, Jiahe Tian, Xiaomin Wan. Evaluation of nigrostriatal damage and its change over weeks in a rat model of Parkinson's disease: small animal positron emission tomography studies with [(11)C]beta-CFT. Nuclear medicine and biology. vol 36. issue 8. 2010-02-03. PMID:19875050. |
since dopamine transporter (dat) is a protein located presynaptically on dopaminergic nerve terminals, radioligands that bind to these sites are promising radiopharmaceuticals for evaluation of the integrity of the dopamine system. |
2010-02-03 |
2023-08-12 |
rat |
| Milan Joksimovic, Angela Anderegg, Anil Roy, Laura Campochiaro, Beth Yun, Raja Kittappa, Ronald McKay, Rajeshwar Awatraman. Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 45. 2010-01-06. PMID:19850875. |
the distinct functions of the dopamine system are carried out by neuroanatomically discrete subgroups of dopamine neurons, which differ in gene expression, axonal projections, and susceptibility in pd. |
2010-01-06 |
2023-08-12 |
Not clear |
| Roy A Wis. Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction. Trends in neurosciences. vol 32. issue 10. 2009-12-03. PMID:19758714. |
forebrain dopamine circuitry has traditionally been studied by two largely independent specialist groups: students of parkinson's disease who study the nigrostriatal dopamine system that originates in the substantia nigra (sn), and students of motivation and addiction who study the role of the mesolimbic and mesocortical dopamine systems that originate in the ventral tegmental area (vta). |
2009-12-03 |
2023-08-12 |
Not clear |
| E Hedlund, T Perlman. Neuronal cell replacement in Parkinson's disease. Journal of internal medicine. vol 266. issue 4. 2009-12-01. PMID:19765180. |
transplantation of foetal dopamine neurons into the striatum of parkinson's disease patients can provide restoration of the dopamine system and alleviate motor deficits. |
2009-12-01 |
2023-08-12 |
Not clear |
| A Guyon, D Skrzydelski, I De Giry, C Rovère, G Conductier, J M Trocello, V Daugé, P Kitabgi, W Rostène, J L Nahon, S Mélik Parsadaniant. Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19477239. |
long term exposure to the chemokine ccl2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release. |
2009-11-10 |
2023-08-12 |
rat |