| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew J Wanat, Ingo Willuhn, Jeremy J Clark, Paul E M Phillip. Phasic dopamine release in appetitive behaviors and drug addiction. Current drug abuse reviews. vol 2. issue 2. 2009-10-16. PMID:19630749. |
in this review, we synthesize the known drug-dependent changes to the dopamine system along with the established functions of phasic dopamine release in order to provide a framework for conceptualizing the role of phasic dopamine release in drug addiction. |
2009-10-16 |
2023-08-12 |
Not clear |
| Anitha P Govind, Paul Vezina, William N Gree. Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19540212. |
mounting evidence suggests that the addictive effects of nicotine, like other drugs of abuse, occur through interactions with its receptors in the mesolimbic dopamine system, particularly ventral tegmental area (vta) neurons, where nicotinic receptors act to modulate the release of dopamine. |
2009-09-21 |
2023-08-12 |
Not clear |
| Fu-Wen Zhou, Ying Jin, Shannon G Matta, Ming Xu, Fu-Ming Zho. An ultra-short dopamine pathway regulates basal ganglia output. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 33. 2009-09-11. PMID:19692618. |
together, our findings indicate that dendritically released dopamine tonically excites snr gaba neurons via d(1)-d(5) receptor coactivation that enhances constitutively active trpc3 channels, forming an ultra-short substantia nigra pars compacta --> snr dopamine pathway that regulates the firing intensity and pattern of these basal ganglia output neurons. |
2009-09-11 |
2023-08-12 |
mouse |
| Lubica Kubíková, Pavel Výboh, Lubor Kostá. Kinetics and pharmacology of the D1- and D2-like dopamine receptors in Japanese quail brain. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19330447. |
although the avian brain dopamine system and its functions have been studied much less than the mammalian one, there is an increasing interest in the role of dopamine and its receptors in a wide variety of motor, cognitive and emotional functions in birds with implications for basic research, medicine or agriculture. |
2009-08-19 |
2023-08-12 |
Not clear |
| Paul J Meyer, Charles K Meshul, Tamara J Phillip. Ethanol- and cocaine-induced locomotion are genetically related to increases in accumbal dopamine. Genes, brain, and behavior. vol 8. issue 3. 2009-07-14. PMID:19220481. |
neuroanatomical research suggests that interactions between dopamine and glutamate within the mesolimbic dopamine system are involved in both drug-induced locomotor stimulation and addiction. |
2009-07-14 |
2023-08-12 |
mouse |
| B Söderpalm, E Löf, M Ericso. Mechanistic studies of ethanol's interaction with the mesolimbic dopamine reward system. Pharmacopsychiatry. vol 42 Suppl 1. 2009-07-01. PMID:19434560. |
the proposed neurocircuitry, has implications for understanding ethanol conditioned dopamine activation, chronic effects of ethanol on the mesolimbic dopamine system and the overall role/importance of dopamine and the nucleus accumbens for the reinforcing effects of ethanol. |
2009-07-01 |
2023-08-12 |
Not clear |
| Christine Stelzel, Ulrike Basten, Christian Montag, Martin Reuter, Christian J Fiebac. Effects of dopamine-related gene-gene interactions on working memory component processes. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19291230. |
in the present study we used a molecular genetic approach to test whether the optimal activity of the dopamine system for different component processes of working memory is additionally related to the availability of dopamine d2 receptors. |
2009-06-09 |
2023-08-12 |
human |
| Nuria Flames, Oliver Hober. Gene regulatory logic of dopamine neuron differentiation. Nature. vol 458. issue 7240. 2009-05-29. PMID:19287374. |
the common denominator of all dopamine neurons is the expression of dopamine pathway genes, which code for a set of phylogenetically conserved proteins involved in dopamine synthesis and transport. |
2009-05-29 |
2023-08-12 |
mouse |
| Nuria Flames, Oliver Hober. Gene regulatory logic of dopamine neuron differentiation. Nature. vol 458. issue 7240. 2009-05-29. PMID:19287374. |
gene regulatory mechanisms that result in the direct activation of dopamine pathway genes and thereby ultimately determine the identity of dopamine neurons are poorly understood in all systems studied so far. |
2009-05-29 |
2023-08-12 |
mouse |
| Nuria Flames, Oliver Hober. Gene regulatory logic of dopamine neuron differentiation. Nature. vol 458. issue 7240. 2009-05-29. PMID:19287374. |
here we show that a simple cis-regulatory element, the dopamine (da) motif, controls the expression of all dopamine pathway genes in all dopaminergic cell types in caenorhabditis elegans. |
2009-05-29 |
2023-08-12 |
mouse |
| Nuria Flames, Oliver Hober. Gene regulatory logic of dopamine neuron differentiation. Nature. vol 458. issue 7240. 2009-05-29. PMID:19287374. |
vertebrate dopamine pathway genes also contain phylogenetically conserved da motifs that can be activated by the mouse ets transcription factor etv1 (also known as er81), and a specific class of dopamine neurons fails to differentiate in mice lacking etv1. |
2009-05-29 |
2023-08-12 |
mouse |
| Jeff A Beeler, Zhen Fang Huang Cao, Mazen A Kheirbek, Xiaoxi Zhuan. Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 5. 2009-05-07. PMID:18704092. |
using a naturally occurring mutant mouse line, aphakia, that lacks a nigrostriatal dopamine pathway but retains an intact mesoaccumbens pathway, we show that the locomotor activating effects of cocaine, including locomotor sensitization, are dependent on an intact nigrostriatal dopamine projection. |
2009-05-07 |
2023-08-12 |
mouse |
| Roy A Wise, Bin Wang, Zhi-Bing Yo. Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one. vol 3. issue 8. 2008-12-18. PMID:18682722. |
intravenous injections of cocaine hcl are habit-forming because, among their many actions, they elevate extracellular dopamine levels in the terminal fields of the mesocorticolimbic dopamine system. |
2008-12-18 |
2023-08-12 |
rat |
| Roy A Wise, Bin Wang, Zhi-Bing Yo. Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one. vol 3. issue 8. 2008-12-18. PMID:18682722. |
to explore the contribution of peripheral effects of cocaine to the early activation of the dopamine system, we used brain microdialysis to measure the effects of cocaine methiodide (mi)--a cocaine analogue that does not cross the blood brain barrier--on glutamate (excitatory) input to the dopamine cells. |
2008-12-18 |
2023-08-12 |
rat |
| Jaime M Hatcher, Kristin C Delea, Jason R Richardson, Kurt D Pennell, Gary W Mille. Disruption of dopamine transport by DDT and its metabolites. Neurotoxicology. vol 29. issue 4. 2008-11-05. PMID:18533268. |
thus, we report that in vitro effects of ddt and its metabolites on components of the dopamine system do not translate into neurotoxicological outcomes in orally exposed mice and ddt appears to have less dopamine toxicity when compared to dieldrin. |
2008-11-05 |
2023-08-12 |
mouse |
| Murray Hong, Karim Mukhida, Ivar Mende. GDNF therapy for Parkinson's disease. Expert review of neurotherapeutics. vol 8. issue 7. 2008-10-01. PMID:18590482. |
experimental studies suggest that gdnf has the ability to protect degenerating dopamine neurons in pd as well as promote regeneration of the nigrostriatal dopamine system. |
2008-10-01 |
2023-08-12 |
Not clear |
| Pu-Yuan Chang, Chia-Hsin Chuang, Jin-Chung Chen, Che-Se Tun. Behavioral and biochemical effects of amperozide and serotonin agents on nigrostriatal and mesolimbic dopamine systems. The Chinese journal of physiology. vol 51. issue 2. 2008-09-08. PMID:18666714. |
overall, we conclude that the modulatory role of amperozide on forebrain dopamine system requires not only 5-ht2/d2 antagonistic but also the blockade of dopamine transporter. |
2008-09-08 |
2023-08-12 |
rat |
| Brenda M Geiger, Gerald G Behr, Lauren E Frank, Angela D Caldera-Siu, Margery C Beinfeld, Efi G Kokkotou, Emmanuel N Potho. Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 22. issue 8. 2008-09-03. PMID:18477764. |
this phenotype was associated with a 50% reduction in basal extracellular dopamine, as measured by a microdialysis probe in the nucleus accumbens, a projection site of the mesolimbic dopamine system that has been implicated in food reward. |
2008-09-03 |
2023-08-12 |
rat |
| Vanessa L Cropley, Masahiro Fujita, William Bara-Jimenez, Amira K Brown, Xiang-Yang Zhang, Janet Sangare, Peter Herscovitch, Victor W Pike, Mark Hallett, Pradeep J Nathan, Robert B Inni. Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPA. Psychiatry research. vol 163. issue 2. 2008-08-22. PMID:18504119. |
this study examined the dopamine system within the frontostriatal circuitry with positron emission tomography (pet) to investigate pre- and post-synaptic dopamine function in relation to the executive processes in pd. |
2008-08-22 |
2023-08-12 |
Not clear |
| Li-Li Liu, Bao-Min Li, Jie Yang, Yu-Wei Wan. Does dopaminergic reward system contribute to explaining comorbidity obesity and ADHD? Medical hypotheses. vol 70. issue 6. 2008-08-13. PMID:18158220. |
in the present article, we proposed that the dopamine system and implicate dopamine genes contribute to explaining the association between adhd and obesity. |
2008-08-13 |
2023-08-12 |
Not clear |