All Relations between 5-ht system and serotonin

Publication Sentence Publish Date Extraction Date Species
Junchao Tong, Jeffrey H Meyer, Isabelle Boileau, Lee-Cyn Ang, Paul J Fletcher, Yoshiaki Furukawa, Stephen J Kis. Serotonin transporter protein in autopsied brain of chronic users of cocaine. Psychopharmacology. vol 237. issue 9. 2020-12-23. PMID:32494974. the long-held speculation that the brain serotonin system mediates some behavioral effects of the psychostimulant cocaine is supported in part by the high affinity of cocaine for the serotonin transporter (sert) and by reports that the serotonin transporter (sert), estimated by sert binding, is increased in brain of human chronic cocaine users. 2020-12-23 2023-08-13 human
Vincent Beliveau, Brice Ozenne, Stephen Strother, Douglas N Greve, Claus Svarer, Gitte Moos Knudsen, Melanie Gan. The structure of the serotonin system: A PET imaging study. NeuroImage. vol 205. 2020-12-18. PMID:31600591. we first outline issues with an existing parcellation of the 5-ht system, and present an alternative parcellation derived from brain mr- and high-resolution pet images of five different 5-ht targets from 210 healthy controls. 2020-12-18 2023-08-13 human
Vincent Beliveau, Brice Ozenne, Stephen Strother, Douglas N Greve, Claus Svarer, Gitte Moos Knudsen, Melanie Gan. The structure of the serotonin system: A PET imaging study. NeuroImage. vol 205. 2020-12-18. PMID:31600591. the parcellation derived here represents a characterization of the 5-ht system which is more stable and explains the underlying 5-ht molecular imaging data better than other atlases, and may hence be more sensitive to capture region-specific changes modulated by 5-ht. 2020-12-18 2023-08-13 human
Michelle M Solleveld, Anouk Schrantee, Judith R Homberg, Paul J Lucassen, Liesbeth Renema. The influence of age-of-onset of antidepressant use on the acute CBF response to a citalopram challenge; a pharmacological MRI study. Psychiatry research. Neuroimaging. vol 303. 2020-12-14. PMID:32592855. therefore, we investigated whether effects of selective serotonin reuptake inhibitor (ssri) treatment on the serotonin system are modulated by age. 2020-12-14 2023-08-13 Not clear
Michael Bade. Inhibition of serotonin synthesis: A novel therapeutic paradigm. Pharmacology & therapeutics. vol 205. 2020-12-10. PMID:31629717. this duality of the serotonin system is enforced by the blood-brain barrier which is impermeable for serotonin. 2020-12-10 2023-08-13 mouse
Paul G Hatini, Kathryn G Common. Serotonin abnormalities in Dravet syndrome mice before and after the age of seizure onset. Brain research. vol 1724. 2020-10-29. PMID:31445030. to further understand the role of serotonin in this disorder, in this study we examined the state of the endogenous serotonin system in an scn1a 2020-10-29 2023-08-13 mouse
Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. we focus on data obtained from three categories of genetically engineered mouse models: (1) mice with altered central 5-ht levels from embryonic stages, (2) mice with deletion of 5-ht receptors from embryonic stages, and (3) mice with altered central 5-ht system exclusively in adulthood. 2020-10-01 2023-08-13 mouse
Kempei Matsuoka, Kiyoe Kato, Tetsuya Takao, Mutsumi Ogawa, Yukie Ishii, Fumiko Shimizu, Junichi Masuda, Akikazu Takad. Concentrations of various tryptophan metabolites are higher in patients with diabetes mellitus than in healthy aged male adults. Diabetology international. vol 8. issue 1. 2020-10-01. PMID:30603309. in the serotonin pathway, when the level of tryptophan is low, the conversion of serotonin to 5-hydroxyindoleacetic acid appears to be accelerated. 2020-10-01 2023-08-13 human
Faranak Vahid-Ansari, Min Zhang, Amin Zahrai, Paul R Alber. Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31114473. since ssris enhance 5-ht, in this review we discuss new findings on the circuitry, development and function of the 5-ht system in modulating behavior, and on how 5-ht neuronal activity is regulated. 2020-10-01 2023-08-13 mouse
Sahar El Aidy, Anouschka S Ramsteijn, Francisco Dini-Andreote, Roel van Eijk, Danielle J Houwing, Joana F Salles, Jocelien D A Olivie. Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28824378. alterations in 5-ht transmission have been linked to pathological symptoms in both intestinal and psychiatric disorders and selective 5-ht transporter (5-htt) inhibitors, affecting the 5-ht system by blocking the 5-ht transporter (5-htt) have been successfully used to treat cns- and intestinal disorders. 2020-09-30 2023-08-13 rat
Gina Griffioen, Granville J Matheson, Simon Cervenka, Lars Farde, Jacqueline Bor. Serotonin 5-HT PeerJ. vol 6. 2020-09-30. PMID:30479884. serotonin 5-ht a putative relationship between markers for the serotonin system and the personality scale self-transcendence (st) and its subscale spiritual acceptance (sa) has been demonstrated in a previous pet study of 5-ht 2020-09-30 2023-08-13 Not clear
Joanna S. Fowler, Gene Jack Wang, Nora D. Volkow, John Ieni, Jean Logan, Naomi Pappas, Stephen L. Dewe. PET Studies of the Effect of the Antidepressant Drugs Nefazodone or Paroxetine on [11C]Raclopride Binding in Human Brain. Clinical positron imaging : official journal of the Institute for Clinical P.E.T. vol 2. issue 4. 2020-09-29. PMID:14516531. this and other reports in the literature indicate that different drugs that affect the serotonin system do not produce consistent and predictable changes in [11c]raclopride binding and that a full understanding of their actions on serotonin and the associated changes in dopamine requires further investigation. 2020-09-29 2023-08-12 human
Yong Xu, Lei Ma, Wei Jiang, Yuhong Li, Gang Wang, Rena L. Study of Sex Differences in Duloxetine Efficacy for Depression in Transgenic Mouse Models. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:29163055. the endogenous estrogen level alters 5-ht system in female mainly, while both da and 5-ht metabolisms were regulated by endogenous estrogen levels after duloxetine administration. 2020-09-29 2023-08-13 mouse
Kai Lin Cham, Tomoko Soga, Ishwar S Parha. Expression of RING Finger Protein 38 in Serotonergic Neurons in the Brain of Nile Tilapia, Frontiers in neuroanatomy. vol 12. 2020-09-29. PMID:30574074. therefore, to gain insight into the role of rnf38 in the central 5-ht system, we identified the neuroanatomical location of 5-ht positive cells and investigated the relationship between rnf38 and the 5-ht system in the brain of the nile tilapia, 2020-09-29 2023-08-13 Not clear
Reem Rafik Alolaby, Poonnada Jiraanont, Blythe Durbin-Johnson, Mittal Jasoliya, Hiu-Tung Tang, Randi Hagerman, Flora Tasson. Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder. Frontiers in genetics. vol 11. 2020-09-28. PMID:32346385. hence, genotypes for 41 subjects (20 on placebo and 21 on sertraline) were determined for several genes involved in the serotonin pathway including the serotonin transporter-linked polymorphic region ( 2020-09-28 2023-08-13 human
Wikrom Wongpaiboonwattana, Oradawan Plong-On, Areerat Hnoonual, Pornprot Limpraser. Significant associations between 5-hydroxytryptaminetransporter-linked promoter region polymorphisms of the serotonin transporter (solute carrier family 6 member 4) gene and Thai patients with autism spectrum disorder. Medicine. vol 99. issue 36. 2020-09-24. PMID:32899028. hyperserotoninemia has been reported in some autistic patients, and several studies have demonstrated an association between 5-hydroxytryptamine-transporter-linked promoter region (5-httlpr) polymorphisms and rs25531 single nucleotide polymorphism in the serotonin transporter gene (solute carrier family 6 member 4; slc6a4) and asd, indicating a possible involvement of the serotonin system in the etiology of asd.to explore this situation further, a case-control association study of 5-httlpr and rs25531 polymorphisms on thai asd patients was conducted. 2020-09-24 2023-08-13 Not clear
Domenico R Caputo, Samuel C Robson, Inge Werner, Alex T For. Complete transcriptome assembly and annotation of a critically important amphipod species in freshwater ecotoxicological risk assessment: Gammarus fossarum. Environment international. vol 137. 2020-09-10. PMID:32028177. an inferior number of hits was found when running a blast analysis of both d. melanogaster and crustacea mrna sequences encoding serotonin receptors available in genbank against the total assembly, compared to other serotonin pathway components. 2020-09-10 2023-08-13 drosophila_melanogaster
Alexander Baxter, Elizabeth K Wood, Christina S Barr, Daniel B Kay, Stephen J Suomi, J Dee Higle. Maternal neglect and the serotonin system are associated with daytime sleep in infant rhesus monkeys. Development and psychopathology. vol 32. issue 1. 2020-08-10. PMID:30712526. serotonin transporter genotype and concentrations of cerebrospinal fluid 5-hydroxyindoleacetic acid (5-hiaa) were used as markers of central serotonin system functioning. 2020-08-10 2023-08-13 human
Masamichi Yokokura, Tatsuhiro Terada, Tomoyasu Bunai, Kyoko Nakaizumi, Yasuhiko Kato, Etsuji Yoshikawa, Masami Futatsubashi, Katsuaki Suzuki, Hidenori Yamasue, Yasuomi Ouch. Alterations in serotonin transporter and body image-related cognition in anorexia nervosa. NeuroImage. Clinical. vol 23. 2020-08-06. PMID:31491815. a recent report proposed that body image distortion (bid), a core symptom of an, may relate to abnormalities of the serotonin system, especially the serotonin transporter (5htt). 2020-08-06 2023-08-13 human
Jens H van Dalfsen, C Rob Marku. The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and the sleep-promoting effects of tryptophan: A randomized placebo-controlled crossover study. Journal of psychopharmacology (Oxford, England). vol 33. issue 8. 2020-07-27. PMID:31237183. the low-expressive short (s) allele of a functional polymorphism (5-httlpr) within the serotonin (5-hydroxytriptamine; 5-ht) transporter gene (slc6a4) has been associated with a reduced functioning of the brain 5-ht system relative to the long (l) allele. 2020-07-27 2023-08-13 Not clear