| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katarzyna Wicha-Komsta, Robert Skibiński, Tomasz Kocki, Waldemar A Turski, Łukasz Komst. HPLC Gradient Retention of Tryptophan and its Metabolites on Three Stationary Phases in Context of Lipophilicity Assessment. Journal of chromatographic science. vol 59. issue 1. 2021-05-03. PMID:33107556. |
this paper is a continuation of lipophilicity research on 14 compounds (tryptophan, kynurenine pathway products, auxin pathway products, serotonin pathway products, tryptamine, as well as two synthetic auxin analogs): indole-2-acetic acid sodium salt (iaa), serotonin, 5-hydroxy-l-tryptophan, tryptamine, l-tryptophan, l-kynurenine (kyn), kynurenic acid (kya), 3-hydroxy-dl-kynurenine, naphtyl-1-acetamide, indole-3-propionic acid (ipa), naphthalene-1-acetic acid (naa), indole-3-butyric acid (iba), indole-3-pyruvic acid (ipv), as well as melatonin. |
2021-05-03 |
2023-08-13 |
Not clear |
| József Bódis, Endre Sulyok, Ákos Várnagy, Miklós Koppán, Gábor Kovács . Investigations of follicular fluid biomarkers in patients undergoing Orvosi hetilap. vol 162. issue 14. 2021-04-02. PMID:33784245. |
it was confirmed that the autocrine/paracrine serotonin system is functional already at the earliest stage of development and both maternal serum and follicular fluid serotonin levels were positively related to the number of mature oocytes (β = 0.447, p = 0.015 and β = 0.443, p = 0.016, respectively) and clinical pregnancy (β = 1.028, p = 0.047). |
2021-04-02 |
2023-08-13 |
Not clear |
| Rajapillai L I Pillai, Elizabeth A Bartlett, Mala R Ananth, Chencan Zhu, Jie Yang, Greg Hajcak, Ramin V Parsey, Christine DeLorenz. Examining the underpinnings of loudness dependence of auditory evoked potentials with positron emission tomography. NeuroImage. vol 213. 2021-02-15. PMID:32169543. |
to examine ldaep's relationship with the serotonin system, we performed pet using serotonin-1a (5-ht |
2021-02-15 |
2023-08-13 |
Not clear |
| Philippe De Deurwaerdère, Giuseppe Di Giovann. Serotonin in Health and Disease. International journal of molecular sciences. vol 21. issue 10. 2021-02-12. PMID:32429111. |
the recent progress made on the function and dysfunction of the 5-ht system will certainly increase the understanding of the widespread role of 5-ht ultimately leading to better apprehend its targeting in human diseases. |
2021-02-12 |
2023-08-13 |
human |
| Ana M Martins, Andreia Ascenso, Helena Margarida Ribeiro, Joana Mart. Current and Future Therapies for Psoriasis with a Focus on Serotonergic Drugs. Molecular neurobiology. vol 57. issue 5. 2021-02-03. PMID:32062841. |
finally, we discuss the role of the serotonin system in psoriasis, and summarize what is known about the effects of antidepressants, in particular specific serotonin reuptake inhibitors, on the physical symptoms of this disease. |
2021-02-03 |
2023-08-13 |
Not clear |
| Karin Hrovatin, Tanja Kunej, Vita Dolža. Genetic variability of serotonin pathway associated with schizophrenia onset, progression, and treatment. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 183. issue 2. 2021-01-04. PMID:31674148. |
genes associated with sz are present on all levels of serotonin pathway: serotonin synthesis, transport, receptor binding, intracellular signaling, and reuptake; however, regulatory genes are poorly researched. |
2021-01-04 |
2023-08-13 |
Not clear |
| Karin Hrovatin, Tanja Kunej, Vita Dolža. Genetic variability of serotonin pathway associated with schizophrenia onset, progression, and treatment. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 183. issue 2. 2021-01-04. PMID:31674148. |
the analysis of reported serotonin pathway-sz associations revealed lack of information about certain serotonin pathway genes potentially associated with sz. |
2021-01-04 |
2023-08-13 |
Not clear |
| Junchao Tong, Jeffrey H Meyer, Isabelle Boileau, Lee-Cyn Ang, Paul J Fletcher, Yoshiaki Furukawa, Stephen J Kis. Serotonin transporter protein in autopsied brain of chronic users of cocaine. Psychopharmacology. vol 237. issue 9. 2020-12-23. PMID:32494974. |
the long-held speculation that the brain serotonin system mediates some behavioral effects of the psychostimulant cocaine is supported in part by the high affinity of cocaine for the serotonin transporter (sert) and by reports that the serotonin transporter (sert), estimated by sert binding, is increased in brain of human chronic cocaine users. |
2020-12-23 |
2023-08-13 |
human |
| Vincent Beliveau, Brice Ozenne, Stephen Strother, Douglas N Greve, Claus Svarer, Gitte Moos Knudsen, Melanie Gan. The structure of the serotonin system: A PET imaging study. NeuroImage. vol 205. 2020-12-18. PMID:31600591. |
we first outline issues with an existing parcellation of the 5-ht system, and present an alternative parcellation derived from brain mr- and high-resolution pet images of five different 5-ht targets from 210 healthy controls. |
2020-12-18 |
2023-08-13 |
human |
| Vincent Beliveau, Brice Ozenne, Stephen Strother, Douglas N Greve, Claus Svarer, Gitte Moos Knudsen, Melanie Gan. The structure of the serotonin system: A PET imaging study. NeuroImage. vol 205. 2020-12-18. PMID:31600591. |
the parcellation derived here represents a characterization of the 5-ht system which is more stable and explains the underlying 5-ht molecular imaging data better than other atlases, and may hence be more sensitive to capture region-specific changes modulated by 5-ht. |
2020-12-18 |
2023-08-13 |
human |
| Michelle M Solleveld, Anouk Schrantee, Judith R Homberg, Paul J Lucassen, Liesbeth Renema. The influence of age-of-onset of antidepressant use on the acute CBF response to a citalopram challenge; a pharmacological MRI study. Psychiatry research. Neuroimaging. vol 303. 2020-12-14. PMID:32592855. |
therefore, we investigated whether effects of selective serotonin reuptake inhibitor (ssri) treatment on the serotonin system are modulated by age. |
2020-12-14 |
2023-08-13 |
Not clear |
| Michael Bade. Inhibition of serotonin synthesis: A novel therapeutic paradigm. Pharmacology & therapeutics. vol 205. 2020-12-10. PMID:31629717. |
this duality of the serotonin system is enforced by the blood-brain barrier which is impermeable for serotonin. |
2020-12-10 |
2023-08-13 |
mouse |
| Paul G Hatini, Kathryn G Common. Serotonin abnormalities in Dravet syndrome mice before and after the age of seizure onset. Brain research. vol 1724. 2020-10-29. PMID:31445030. |
to further understand the role of serotonin in this disorder, in this study we examined the state of the endogenous serotonin system in an scn1a |
2020-10-29 |
2023-08-13 |
mouse |
| Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. |
we focus on data obtained from three categories of genetically engineered mouse models: (1) mice with altered central 5-ht levels from embryonic stages, (2) mice with deletion of 5-ht receptors from embryonic stages, and (3) mice with altered central 5-ht system exclusively in adulthood. |
2020-10-01 |
2023-08-13 |
mouse |
| Kempei Matsuoka, Kiyoe Kato, Tetsuya Takao, Mutsumi Ogawa, Yukie Ishii, Fumiko Shimizu, Junichi Masuda, Akikazu Takad. Concentrations of various tryptophan metabolites are higher in patients with diabetes mellitus than in healthy aged male adults. Diabetology international. vol 8. issue 1. 2020-10-01. PMID:30603309. |
in the serotonin pathway, when the level of tryptophan is low, the conversion of serotonin to 5-hydroxyindoleacetic acid appears to be accelerated. |
2020-10-01 |
2023-08-13 |
human |
| Faranak Vahid-Ansari, Min Zhang, Amin Zahrai, Paul R Alber. Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31114473. |
since ssris enhance 5-ht, in this review we discuss new findings on the circuitry, development and function of the 5-ht system in modulating behavior, and on how 5-ht neuronal activity is regulated. |
2020-10-01 |
2023-08-13 |
mouse |
| Sahar El Aidy, Anouschka S Ramsteijn, Francisco Dini-Andreote, Roel van Eijk, Danielle J Houwing, Joana F Salles, Jocelien D A Olivie. Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28824378. |
alterations in 5-ht transmission have been linked to pathological symptoms in both intestinal and psychiatric disorders and selective 5-ht transporter (5-htt) inhibitors, affecting the 5-ht system by blocking the 5-ht transporter (5-htt) have been successfully used to treat cns- and intestinal disorders. |
2020-09-30 |
2023-08-13 |
rat |
| Gina Griffioen, Granville J Matheson, Simon Cervenka, Lars Farde, Jacqueline Bor. Serotonin 5-HT PeerJ. vol 6. 2020-09-30. PMID:30479884. |
serotonin 5-ht a putative relationship between markers for the serotonin system and the personality scale self-transcendence (st) and its subscale spiritual acceptance (sa) has been demonstrated in a previous pet study of 5-ht |
2020-09-30 |
2023-08-13 |
Not clear |
| Joanna S. Fowler, Gene Jack Wang, Nora D. Volkow, John Ieni, Jean Logan, Naomi Pappas, Stephen L. Dewe. PET Studies of the Effect of the Antidepressant Drugs Nefazodone or Paroxetine on [11C]Raclopride Binding in Human Brain. Clinical positron imaging : official journal of the Institute for Clinical P.E.T. vol 2. issue 4. 2020-09-29. PMID:14516531. |
this and other reports in the literature indicate that different drugs that affect the serotonin system do not produce consistent and predictable changes in [11c]raclopride binding and that a full understanding of their actions on serotonin and the associated changes in dopamine requires further investigation. |
2020-09-29 |
2023-08-12 |
human |
| Yong Xu, Lei Ma, Wei Jiang, Yuhong Li, Gang Wang, Rena L. Study of Sex Differences in Duloxetine Efficacy for Depression in Transgenic Mouse Models. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:29163055. |
the endogenous estrogen level alters 5-ht system in female mainly, while both da and 5-ht metabolisms were regulated by endogenous estrogen levels after duloxetine administration. |
2020-09-29 |
2023-08-13 |
mouse |